[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postdural-puncture-headache\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postdural-puncture-headache":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100624523","effect-of-coffee-on-postdural-puncture-headache-after-cesarean-section-100624523",false,"NCT07410741","Effect of Coffee on Postdural Puncture Headache After Cesarean Section","The Effect of Postoperative Coffee Consumption on Postdural Puncture Headache and Analgesic Use in Women Undergoing Cesarean Section With Spinal Anesthesia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Ability to read, understand, and communicate in Turkish\n* Age ≥ 18 years\n* Undergoing cesarean section under spinal anesthesia\n* Spinal anesthesia administered in the sitting position\n* Initiation of oral intake at postoperative hour 6\n* No history of physiological discomfort related to coffee consumption based on prior experience (e.g., insomnia, palpitations, headache)\n* Ability to understand the study procedures and communicate adequately to provide informed consent\n\nExclusion Criteria:\n\n* Patients undergoing emergency cesarean section\n* Patients with a history of migraine or other types of chronic headache disorders\n* Patients in whom spinal anesthesia was converted to general anesthesia.\n* Patients whose oral intake was postponed for any reason in the postoperative period.\n* Patients with high-risk pregnancies.\n* Use of caffeine-containing analgesic medications during the postoperative period.\n* Postoperative cigarette smoking.",true,"FEMALE","18 Years",{"count":20,"type":21},82,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to investigate the effects of postoperative coffee consumption on postdural puncture headache (PDPH) and analgesic use in women undergoing cesarean section with spinal anesthesia.",[27],"Postdural Puncture Headache",[29,30,31,32,33],"Post-Dural Puncture Headache","spinal anesthesia","caffeine","cesarean section","coffee","RECRUITING","2026-02-26",{"date":37,"type":38},"2026-03-02","ACTUAL",{"date":40,"type":38},"2026-02-20",{"date":42,"type":21},"2026-12",{"name":44,"class":45},"Hacettepe University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":46},"100598775","neutrophil-to-lymphocyte-ratio-and-postdural-headache-100598775","NCT07075874","Neutrophil to Lymphocyte Ratio and Postdural Headache","Preoperative Neutrophil-to-Lymphocyte Ratio as a Predictor of Post-Dural Puncture Headache Following Cesarean Section Under Spinal Anesthesia","Inclusion Criteria:\n\n* Women aged 18 years or older\n* Underwent elective or emergency cesarean section under spinal anesthesia\n* Had complete preoperative complete blood count (CBC) data available\n* No known hematological or inflammatory disease\n* No intraoperative complications recorded\n* Medical records accessible for postoperative follow-up regarding PDPH symptoms\n\nExclusion Criteria:\n\n* Age under 18\n* Absence of preoperative complete blood count data\n* Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy\n* Platelet count \\\u003C150,000\u002Fmm³ or INR \\>1.5\n* Incomplete or missing medical records",{"count":55,"type":21},821,"OBSERVATIONAL","This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture headache (PDPH) in obstetric patients undergoing cesarean section under spinal anesthesia.",[59,27],"Preoperative Neutrophil-to-Lymphocyte Ratio (NLR)","2025-07-19",{"date":62,"type":38},"2025-07-24",{"date":64,"type":38},"2025-07-12",{"date":66,"type":21},"2025-07-17",{"name":68,"class":45},"Istinye University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":17,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":22,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":46},"100572129","phase-4-a-prospective-cohort-study-to-evaluate-the-safety-efficacy-and-usability-of-the-epizact-device-100572129","NCT06729255","A Prospective Cohort Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device","A Single Academic Center, Prospective Cohort With Retrospective Loss-of-resistance Comparator, Proof of Concept Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device for Parturients Undergoing Epidural Labor Analgesia","Inclusion Criteria:\n\n* Pregnant women requesting labor epidural analgesia\n* Women pregnant with a single baby (not twins or triplets)\n\nExclusion Criteria:\n\n* Women requesting not to have a labor epidural\n* Height less than 150 cm\n* A bleeding disorder, nerve problem, or skin infection that contraindicates receiving an epidural\n* A women receiving a combined spinal epidural (CSE) or a dural puncture epidural (DPE)\n* A history of spine surgery\n* Allergy to local anesthetics (numbing medicine) or skin cleaning solutions\n* Decisionally impaired individuals","15 Years","50 Years",{"count":79,"type":21},100,[81],"PHASE4","The purpose of the study is to learn more about a new device, the EpiZact Epidural Device, that may be helpful for reducing the likelihood of wet tap when a labor epidural is placed. When epidurals are placed correctly the needle stops just in front of the space in the body that contains cerebrospinal fluid. When the epidural is advanced a short distance further, leakage of cerebrospinal fluid can occur. This is known as a wet tap. A wet tap can result in a severe headache and at times other complications. The goal of this clinical trial is to learn if the use of the EpiZact device prevents wet taps in pregnant women receiving epidurals for relief of labor pain. The main questions this study aims to answer are:\n\n1. What the rate of wet tap with the EpiZact device?\n2. What is the rate of failed epidural placement with the EpiZact device?\n\nAll patients in the study will receive an epidural with the EpiZact device. The investigators will compare the results with patients not in the study that receive an epidural without the EpiZact device.",[27,84],"Epidural Analgesia, Obstetric",[86,87,88],"EpiZact","Wet Tap","unintentional dural puncture","NOT_YET_RECRUITING","2025-02-11",{"date":92,"type":38},"2025-02-14",{"date":94,"type":21},"2025-03-15",{"date":96,"type":21},"2026-12-31",{"name":98,"class":45},"Oregon Health and Science University"]