[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"posterior-capsule-opacification\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:posterior-capsule-opacification":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,57],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100609329","clinical-evaluation-of-low-contrast-visual-performance-and-low-light-phenomena-in-patients-with-various-intraocular-lens-implants-100609329",false,"NCT07213167","Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants","Clinical Evaluation of Low Contrast Defocus Curves, Low Light Photic Phenomena, and Dysphotopsia Profiles in Pseudophakic Patients","Inclusion Criteria:\n\n* Minimum 22 years of age\n* Bilateral pseudophakia, at least 3 months postoperative from IOL implantation, with one of the study IOL models in at least one eye.\n* Availability, willingness, and sufficient cognitive awareness to comply with examination procedures\n* Signed informed consent and HIPAA authorization or equivalent documentation necessary to comply with applicable privacy laws pertaining to medical treatment in the governing countries\n* Ability to understand and respond to a questionnaire in English\n\nExclusion Criteria:\n\n* Any clinically significant pupil abnormalities (non-reactive, fixed pupils, or abnormally shaped pupils.\n* Inability to focus or fixate for prolonged periods of time (e.g., due to strabismus, nystagmus, etc.)\n* Uncorrected distance visual acuity worse than 20\u002F25 in either eye\n* Prior corneal refractive surgery (LASIK, LASEK, RK, PRK, etc.) or intraocular surgery. Note: Prophylactic peripheral iridotomies and peripheral laser retinal repairs that, in the opinion of the investigator will not confound study outcomes are acceptable.\n* Posterior capsular opacification with grading worse than 1+\n* Ocular findings that may, in the opinion of the investigator, affect vision and\u002For contrast sensitivity","ALL","22 Years",{"count":19,"type":20},120,"ESTIMATED","1 Day","OBSERVATIONAL","The goal of this clinical investigation is to evaluate visual acuity and contrast sensitivity in low lighting conditions using several different testing devices, and measure nighttime side effects of intraocular lens (IOL) implants after cataract surgery.\n\nResearchers will compare the results for three different types of IOLs to see how each lens contributes to overall visual function, patient experience and satisfaction.\n\nParticipants will:\n\n* Complete two different questionnaires about their current vision\n* Undergo visual testing using several different devices",[25,26,27,28,29],"Dysphotopsia","Posterior Capsule Opacification","Visual Acuity","Visual Function","Contrast Sensitivity",[25,26,31,32,33,34,35,36,37,38,39,40,41,42,43],"Halometry","Manifold Vision Meter","PRVSQ","AIOLIS","TECNIS Eyhance IOL","TECNIS Symfony Optiblue IOL","TECNIS Odyssey IOL","Low Contrast","Defocus Curves","Low Light Photic Phenomena","Dysphotopsia Profiles","Pseudophakia","TECNIS 1-Piece","RECRUITING","2026-03-31",{"date":47,"type":48},"2026-04-06","ACTUAL",{"date":50,"type":48},"2025-09-24",{"date":52,"type":20},"2026-08",{"name":54,"class":55},"Dr. Daniel H. Chang, MD","OTHER",1,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":79},"100520705","ic-8-apthera-iol-new-enrollment-post-approval-study-100520705","NCT06060041","IC-8 Apthera IOL New Enrollment Post Approval Study","Inclusion Criteria:\n\n* 22 years of age or older, any race and any gender;\n* Posterior capsule opacification (PCO) requiring treatment in the IC-8 Apthera IOL eye\n* Able to comprehend and have signed a statement of informed consent;\n* Availability, willingness, ability and sufficient cognitive awareness to comply with examination procedures and study visits;\n* Clear intraocular media in both eyes;\n* Preoperative corneal astigmatism ≤1.5 D in the IC-8 Apthera IOL eye prior to IC-8 Apthera implantation;\n* Prior IC-8 Apthera IOL implantation in one eye and a monofocal\u002Fmonofocal toric IOL in the other eye in accordance with the directions for use (DFU) for each IOL.\n\nExclusion Criteria:\n\n* Pharmacologically dilated pupil size less than 7.0 mm in the IC-8 Apthera IOL eye;\n* Irregular astigmatism in either eye;\n* History of retinal disease;\n* Active or recurrent anterior segment pathology;\n* Presence of ocular abnormalities;\n* Diagnosis of dry eye in which patients are unable to maintain eye comfort or adequate vision even with dry eye treatment;\n* Previous corneal or intraocular surgery, except cataract surgery;\n* History of ocular trauma or ocular conditions expected to require retinal laser treatment or other surgical intervention;\n* Acute, chronic or uncontrolled systemic disease that would, in the opinion of the investigator, confound the outcomes of the study;\n* Patient is pregnant, plans to become pregnant, is lactating or has another condition associated with hormonal fluctuation that could lead to refractive changes and dry eye;\n* Concurrent participation or participation in any clinical trial up to 30 days prior to the first visit in the study.\n* Subjects who plan to be traveling, relocating or otherwise unavailable to attend any of the visits",{"count":64,"type":20},435,"The purpose of this study is to verify the post-market safety of the IC-8 Apthera IOL after the treatment of posterior capsular opacification (PCO), an expected complication related to IC-8 Apthera IOL implantation.",[67,68,26],"Cataract","Presbyopia","2026-01-09",{"date":71,"type":48},"2026-01-12",{"date":73,"type":48},"2023-09-08",{"date":75,"type":20},"2027-09-30",{"name":77,"class":78},"Bausch & Lomb Incorporated","INDUSTRY",14]