[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"posterior-crossbite\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:posterior-crossbite":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100616154","leaf-expander-versus-hyrax-expander-in-mixed-dentition-patients-with-posterior-crossbite-100616154",false,"NCT07301918","Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite.","Evaluation of the Effects of the Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite: A Randomized Clinical Trial.","Inclusion Criteria:\n\n* Male and female patients\n* Mixed dentition stage\n* Unilateral or bilateral posterior crossbite.\n* Patients in prepubertal stage with cervical vertebral maturation stage 1-3.\n* Fully erupted maxillary and mandibular permanent first molars.\n* Skeletal class I or II.\n\nExclusion Criteria:\n\n* Previous orthodontic treatment.\n* Missing teeth.\n* Inadequate oral hygiene.\n* Patients with bad oral habits.\n* Patients with medical conditions.\n* Patients with cleft lip and palate.","ALL","6 Years","12 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","Design: Two-arm parallel randomized clinical trial in mixed dentition (6-12 years).\n\nArms: (1) 9 mm, 900 g leaf expander; (2) 9 mm Hyrax expander. Follow-up: From appliance insertion → completion of intended expansion → 6-month retention.\n\nPrimary outcome: Pain perception during the first 7 days post-insertion (daily patient-reported scale).\n\nSecondary outcomes: Skeletal and dental changes on CBCT.",[27,28],"Posterior Crossbite","Maxilla; Hypoplasia",[30,31,32,33],"expander","maxillary transverse deficiency","posterior crossbite","mixed dentition","RECRUITING","2026-06-03",{"date":37,"type":38},"2026-06-04","ACTUAL",{"date":40,"type":38},"2025-10-01",{"date":42,"type":21},"2027-03",{"name":44,"class":45},"Cairo University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":18,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":75,"leadSponsor":77,"locationsCount":46},"100631401","quad-helix-vs-rme-for-posterior-cross-bite-in-egyptian-children-100631401","NCT07500194","Quad Helix vs RME for Posterior Cross-bite in Egyptian Children","Quad Helix Versus Rapid Maxillary Expanders in the Treatment of Posterior Cross-bite During Mixed Dentition in a Sample of Egyptian Children: A Randomized Clinical Study.","Expansion","Inclusion Criteria:\n\n1. Children aged 9-12 years in the mixed dentition stage\n2. Presence of posterior cross-bite due to transverse maxillary deficiency\n3. No previous history of orthodontic treatment\n4. Good oral hygiene and cooperative behavior\n5. No significant antero-posterior or vertical skeletal discrepancies\n\nExclusion Criteria:\n\n1. Patient with craniofacial anomalies\n2. Presence of systemic diseases or syndromes affecting bone metabolism\n3. Extensive dental caries or untreated periodontal disease\n4. History of trauma or surgery affecting the maxilla or mandible","9 Years",{"count":57,"type":21},20,[24],"This randomized clinical trial aims to evaluate and compare the effectiveness of the Quad Helix (QH) appliance versus Rapid Maxillary Expanders (RME) in treating posterior cross-bite in Egyptian children during the mixed dentition stage. The study will also assess patient comfort and pain levels associated with each appliance.",[27,61,62],"Maxillary Expansion","Transverse Maxillary Deficiency",[64,65,66,67,68,69],"Quad Helix","Rapid Maxillary Expansion","Posterior cross-bite","Mixed Dentition","Egyptian children","Randomized clinical trials","NOT_YET_RECRUITING","2026-03-24",{"date":73,"type":38},"2026-03-30",{"date":73,"type":21},{"date":76,"type":21},"2028-03-31",{"name":78,"class":45},"Al-Azhar University"]