[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postinduction-hypotension\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postinduction-hypotension":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100634338","continuous-versus-bolus-norepinephrine-administration-to-treat-postinduction-hypotension-100634338",false,"NCT07538388","Continuous Versus Bolus Norepinephrine Administration to Treat Postinduction Hypotension","Continuous Versus Bolus Norepinephrine Administration to Treat Postinduction Hypotension in High-Risk Non-Cardiac Surgery Patients - The Multicenter INDUCT Trial (INDUCT-Multi)","INDUCT-Multi","Inclusion Criteria:\n\nWe will include consenting patients ≥45 years scheduled for elective non-cardiac surgery under general anesthesia with planned continuous intra-arterial blood pressure monitoring with a radial arterial catheter and with at least two of the following risk criteria for developing acute kidney injury:\n\n* Age ≥65 years\n* ASA physical status III or IV\n* Chronic arterial hypertension\n* Diabetes mellitus requiring medication\n* Intra-abdominal surgery\n* Preoperative renal insufficiency (serum creatinine ≥1.2 mg\u002FdL)\n\nExclusion Criteria:\n\n* Pregnancy\n* Cardiac arrhythmia\n* History of intracranial hemorrhage or intracranial aneurysm\n* Clinical indication for continuous norepinephrine infusion during induction of general anesthesia (e.g., severe aortic valve stenosis, coronary artery disease, or heart failure)\n* Patients who are unable to understand, read, and provide informed consent in German","ALL","45 Years",{"count":20,"type":21},446,"ESTIMATED","INTERVENTIONAL",[24],"NA","INDUCT-Multi is a multicenter randomized trial investigating whether continuous, compared to bolus, administration of norepinephrine during induction of general anesthesia reduces postinduction hypotension in high-risk non-cardiac surgery patients.",[27],"Postinduction Hypotension",[29,30,31,32,33,34],"postinduction hypotension","non-cardiac surgery","norepinephrine","bolus","hypotension","continuous","RECRUITING","2026-06-24",{"date":38,"type":39},"2026-06-29","ACTUAL",{"date":41,"type":39},"2026-05-07",{"date":43,"type":21},"2026-12",{"name":45,"class":46},"Universitätsklinikum Hamburg-Eppendorf","OTHER",4]