[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postoperative-complications-cardiopulmonary\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postoperative-complications-cardiopulmonary":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,52,78,119,149,174,205,242],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":4},"100642479","ventilation-modalities-during-transport-of-postoperative-critically-ill-patients-to-the-icu-100642479",false,"NCT07646249","VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU","VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU - A Multicenter Observational Study","VENTICRIT","Inclusion criteria\n\n* Intubated patients undergoing general anesthesia for non-cardiac surgery\n* Requirement for postoperative IMV\n* Age ≥18 years\n* Obtained informed consent Exclusion criteria\n* Patients undergoing cardiac surgery\n* Patients receiving preoperative mechanical ventilation prior to surgery.","ALL","18 Years",{"count":20,"type":21},800,"ESTIMATED","OBSERVATIONAL","Patients undergoing major non-cardiac surgery may require postoperative mechanical ventilation and transfer from the operating room to the intensive care unit (ICU). This intra-hospital transport phase is critical, as patients may experience changes in respiratory and hemodynamic status, including alterations in oxygenation, ventilation, blood pressure, and heart rate.\n\nDuring transport, ventilatory support may be provided using different strategies, including manual ventilation with a bag-valve device or mechanical ventilation with a portable ventilator. Although both approaches are commonly used in clinical practice, there is limited evidence comparing their effects on respiratory function, gas exchange, and overall physiological stability during and after transport.\n\nThis multicenter, prospective observational study aims to describe current clinical practices in ventilatory support during intra-hospital transport in adult patients undergoing non-cardiac surgery who require ICU admission. The study will also evaluate changes in vital signs, arterial blood gas parameters, and respiratory mechanics, as well as the occurrence of adverse events during transport and postoperative pulmonary complications within the first five days after surgery.\n\nNo additional interventions or procedures beyond standard clinical care will be performed. All data will be collected as part of routine clinical practice. The results of this study are expected to improve the understanding of ventilation management during transport and to identify safer and more effective strategies for critically ill postoperative patients.",[25,26,27,28,29,30],"Respiration, Artificial","Positive-Pressure Respiration","Postoperative Complications (Cardiopulmonary)","Postoperative Complications","Critical Illness","Intensive Care Units",[32,33,34,25,26,35,28,36,29,30,37,38,39],"Intra-hospital Transport","Mechanical Ventilation","Manual Ventilation","Postoperative Care","Postoperative Pulmonary Complications","Endotracheal Intubation","General Anesthesia","Non-Cardiac Surgery","NOT_YET_RECRUITING","2026-06-09",{"date":43,"type":44},"2026-06-12","ACTUAL",{"date":46,"type":21},"2026-07-01",{"date":48,"type":21},"2027-10-01",{"name":50,"class":51},"Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva","OTHER",{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100619861","bis-in-icu-interventional-study-100619861","NCT07350122","BIS in ICU Interventional Study","Effect of BIS-Guided Sedation on Clinical Outcomes in Postoperative Cardiac Surgery ICU Patients: A Prospective, Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Undergoing cardiac surgery with subsequent admission to the intensive care unit (e.g., valve surgery, coronary artery bypass grafting, aortic surgery)\n* Planned or expected duration of invasive mechanical ventilation \\> 6 hours postoperatively\n* Requirement for continuous sedation during ICU stay\n\nExclusion Criteria:\n\n* Pre-existing neurological disorders affecting consciousness or sedation assessment (e.g., severe dementia, epileptic encephalopathy).\n* Acute neurological events in the perioperative period (e.g., stroke, intracranial hemorrhage).\n* Severe hepatic dysfunction (Child-Pugh Class C).\n* Participation in another interventional study potentially affecting sedation or cognitive outcomes.\n* Pregnancy or lactation.\n* Do-not-intubate (DNI)\u002FDo-not-resuscitate (DNR) orders or documented limitation of therapy.\n* Patients in whom short-term survival is deemed unlikely due to the clinical course.",{"count":60,"type":21},144,"INTERVENTIONAL",[63],"NA","This study will test whether using a Bispectral Index (BIS) monitor to guide sedation can reduce the amount of sedative medication given to adults in the intensive care unit (ICU) after cardiac surgery. BIS is a non-invasive, EEG-based monitor that shows a number from 0-100 to reflect level of consciousness. Researchers will compare BIS-guided sedation to standard sedation guided by clinical scales (such as the Richmond Agitation-Sedation Scale, RASS).\n\nAbout 144 participants will be randomly assigned (1:1) to one of two groups at two hospitals in Austria (Medical University of Graz and Klinikum Wels-Grieskirchen). In the BIS group, clinicians will use BIS values and standard care to titrate sedation and will aim to avoid sustained BIS values below 50. In the control group, sedation will follow standard practices using clinical scales; BIS will be recorded but hidden from caregivers. The trial is open-label for treating staff; outcome assessors and data analysts will be blinded.\n\nParticipants will be in the study during their ICU sedation and mechanical ventilation period (typically more than 6 hours), with follow-up through ICU and hospital discharge. The primary outcome is the time-averaged dose of propofol (mg\u002Fkg\u002Fh) given during continuous ICU sedation until weaning (up to 72 hours). Secondary outcomes include duration of ventilation and sedation, depth of sedation measures, sedative and catecholamine doses, pulmonary infections (including ventilator-associated pneumonia), ICU and hospital length of stay, delirium, and in-hospital mortality.\n\nRisks are minimal and may include mild skin irritation from forehead electrodes. Possible benefits include improved sedation management; benefits are not guaranteed. Taking part is voluntary.",[66,29,27,67,68],"Cardiac Surgical Procedures (Postoperative Population)","Delirium - Postoperative","Pneumonia, Ventilator-Associated","2026-05-28",{"date":71,"type":44},"2026-05-29",{"date":73,"type":21},"2026-07",{"date":75,"type":21},"2027-06",{"name":77,"class":51},"Medical University of Graz",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":17,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":107,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":118},"100637012","pupillometry-in-identifying-risk-of-postoperative-opioid-induced-respiratory-depression-in-children-undergoing-tonsillectomy-100637012","NCT07573150","Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy","Pupillometry in Identifying Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy","Inclusion Criteria:\n\n* Age 3 to less than 18 years\n* Scheduled to undergo tonsillectomy with or without adenoidectomy\n* Planned postoperative recovery in a monitored clinical setting (e.g., post-anesthesia care unit)\n* Ability to obtain informed consent from parent or legal guardian and assent from the participant when developmentally appropriate\n\nExclusion Criteria:\n\n* Known neurologic or ophthalmologic conditions that may affect pupillary function\n* Use of medications known to significantly alter pupillary response outside of standard perioperative care\n* Inability to obtain adequate pupillometry measurements (e.g., due to eye injury or inability to safely perform measurement)\n* Patients not receiving opioids as part of perioperative care\n* Any condition that, in the opinion of the investigator, would interfere with study participation or data interpretation",true,"3 Years","17 Years",{"count":89,"type":21},300,"This study will evaluate whether quantitative pupillometry measurements can be used to identify children at risk for postoperative opioid-induced respiratory depression (OIRD) following tonsillectomy. Opioid-induced respiratory depression is a serious and potentially life-threatening complication that can occur after surgery, and current monitoring approaches are limited in their ability to predict which patients are at highest risk.\n\nIn this prospective observational cohort study, approximately 300 pediatric patients undergoing tonsillectomy will undergo non-invasive pupillometry measurements at defined perioperative time points, including preoperative, intraoperative, and postoperative periods. Pupillometry measurements will be collected using a commercially available, FDA-regulated infrared pupillometer. These measurements will include pupil size, constriction and dilation velocities, and latency in response to light stimulation.\n\nPupillometry data will be collected for research purposes only and will not be used to guide clinical care or treatment decisions. Standard clinical care will not be altered as part of this study. Clinical outcomes, including the occurrence of postoperative opioid-induced respiratory depression, opioid use, sedation levels, pain scores, and other postoperative events, will be recorded from the medical record.\n\nThe goal of this study is to evaluate the relationship between pupillary response patterns and the occurrence of postoperative respiratory depression, and to support the development of predictive models that may improve early identification of patients at risk for opioid-related adverse events.",[92,27,93],"Opioid-Induced Respiratory Depression","Respiratory Complications Due to Anesthesia",[95,96,97,98,99,100,101,102,103,104,105,92,106],"Sedation","Postoperative Period","Perioperative Monitoring","Pediatrics","Pupillary Light Reflex","Pupillometry","Analgesia","Anesthesia","Opioids","Hypoventilation","Oxygen Desaturation","Respiratory Depression","RECRUITING","2026-05-06",{"date":110,"type":44},"2026-05-08",{"date":112,"type":44},"2026-05-04",{"date":114,"type":21},"2027-04-30",{"name":116,"class":117},"NeurOptics Inc","INDUSTRY",2,{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":125,"eligibilityCriteria":126,"healthyVolunteers":85,"sex":17,"minAge":127,"maxAge":4,"enrollmentInfo":128,"targetDuration":130,"studyType":22,"phases":4,"briefSummary":131,"conditions":132,"keywords":133,"overallStatus":107,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":148},"100632903","preoperative-exercise-testing-and-perioperative-outcomes-100632903","NCT07519733","Preoperative Exercise Testing and Perioperative Outcomes","Submaximal Cardiopulmonary Exercise Testing in Adults Presenting for Moderate to High-risk Surgery and Perioperative Outcomes","SAMPO","Inclusion Criteria:\n\n* greater than 45 years old\n* moderate to high-risk noncardiac surgery\n* surgeon, anesthesiologist or other medical provider requested referral for preoperative high risk evaluation, or\n* revised cardiac risk index \\> or = 2, or\n* Ambiguous, low or discordant functional capacity by either the Duke Activity status index (DASI \\\u003C34) or the modified Duke Activity status index (\\\u003C or =3) or\n* Frailty Index \\>1\n\nExclusion Criteria:\n\n* Age \\\u003C45\n* Absolute contraindication to submaximal cardiopulmonary exercise testing\n* Impaired decision making capacity\n* Prisoners\n* Pregnancy\n* Severe peripheral vascular disease\n* Functional limitation precluding the performance of submaximal cardipulmonary exercise testing\n* Severe active pulmonary disease","45 Years",{"count":129,"type":21},992,"1 Year","The goal of this observational study is to learn whether results from a brief exercise test done before surgery can help identify adults who may be more likely to have problems after moderate- to high-risk noncardiac surgery. The study includes adults older than 45 years who are seen in a pre-surgical evaluation clinic and complete submaximal cardiopulmonary exercise testing, or smCPET, as part of their usual clinical care. The main questions it aims to answer are:\n\nAre smCPET measurements linked with early problems after surgery? Are smCPET measurements linked with later problems after surgery, including complications within 30 and 60 days, longer hospital stay, and death? Can smCPET add useful information to standard preoperative risk assessment? Researchers will observe and analyze information collected during routine care. No extra exercise testing or treatment will be done for research.\n\nParticipants will:\n\n* Complete routine preoperative evaluation in the Yale Pre-Surgical Evaluation Clinic.\n* Undergo smCPET if it is ordered as part of standard clinical care.\n* Allow researchers to collect information from the medical record and from the exercise test for the study repository, if they agree to participate.\n\nThe study will collect de-identified information about each participant's health before surgery, exercise test results, details about the surgery and hospital stay, and problems that happen after surgery. This may include age, sex, body mass index, other medical conditions, routine lab and imaging results, heart rate, blood pressure, oxygen levels, smCPET measures such as peak oxygen uptake, anaerobic threshold, and breathing efficiency, and early and late postoperative outcomes.\n\nResearchers will look at short-term and later outcomes after surgery. These include problems identified during the hospital stay, such as heart, lung, kidney, nerve, blood, wound, and pain-related complications, as well as complications within 30 and 60 days after surgery. Researchers will also study hospital length of stay and death after surgery.\n\nThis study is designed to help researchers understand whether a short, practical exercise test can improve the way surgical risk is assessed before an operation. Current preoperative assessment tools do not always measure how well the heart, lungs, and muscles work together during physical stress. smCPET may provide a more objective way to measure functional capacity and physiologic reserve in a busy clinic setting.\n\nThis is a single-center study based in a preoperative evaluation clinic. The study has a prospective observational cohort component and a retrospective validation component. In the prospective part, adults who meet clinic criteria and complete smCPET during routine care may be asked to join the repository. In the retrospective part, researchers may also review historical data from patients evaluated before smCPET was put into routine use to help compare outcomes and validate findings.\n\nBecause this is an observational repository study, participation does not change the care participants receive. The exercise test is done for clinical reasons, not because of the research study. The research team will not assign treatments or decide what surgery a participant has. Instead, the team will study how exercise test findings relate to outcomes that occur after surgery.\n\nThe long-term aim of this study is to improve preoperative risk assessment and help clinicians better identify patients who may need closer monitoring, more evaluation, or more support around the time of surgery. If the findings are useful, they may support broader use of brief preoperative exercise testing in adults having higher-risk noncardiac surgery.",[27],[134,135,136,137,138],"preoperative evaluation","submaximal cardiopulmonary exercise testing","major adverse cardiovascular events","preoperative risk stratification","high risk evaluation","2026-04-02",{"date":141,"type":44},"2026-04-09",{"date":143,"type":44},"2025-07-23",{"date":145,"type":21},"2028-07-30",{"name":147,"class":51},"Yale University",1,{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":156,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":158,"conditions":159,"keywords":4,"overallStatus":107,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":169,"leadSponsor":171,"locationsCount":118},"100622998","gls-in-difficult-cpb-weaning-100622998","NCT07390903","GLS in Difficult CPB Weaning","Global Longitudinal Strain as a Predictor of Difficult Separating From Cardiopulmonary Bypass","Inclusion Criteria\n\n* Age \\> 18 years.\n* Scheduled for elective cardiac surgery requiring cardiopulmonary bypass (CPB).\n* Provided written informed consent to participate.\n* Eligible surgical procedures include:\n\n  * Isolated mitral valve replacement or repair.\n  * Isolated aortic valve replacement or repair.\n  * Isolated coronary artery bypass grafting (CABG).\n  * Combined valve and CABG surgery.\n  * Multiple valve replacement or repair.\n  * Surgery involving the ascending aorta or aortic arch.\n\nExclusion Criteria\n\n* Emergency cardiac surgery.\n* Redo cardiac surgery.\n* Contraindications to transesophageal echocardiography (TEE).\n* Critical preoperative conditions, including:\n\n  * Ongoing inotropic drug therapy.\n  * Preoperative mechanical circulatory support (e.g., IABP, ECMO, VAD).\n  * Requirement for mechanical ventilation.\n  * Preoperative atrial fibrillation.",{"count":157,"type":21},213,"The goal of this observational study is to learn whether global longitudinal strain (GLS), measured by echocardiography, can predict difficulty separating from cardiopulmonary bypass (CPB) in adults undergoing elective cardiac surgery.\n\nThe main questions it aims to answer are:\n\n* Can preoperative GLS measurement predict difficult separation from CPB?\n* Are GLS values associated with outcomes such as intensive care unit (ICU) stay, hospital stay, cardiac biomarkers, or 30-day mortality?\n\nParticipants will:\n\n* Undergo standard cardiac surgery requiring CPB\n* Have echocardiographic assessments (TTE before and after surgery)\n* Have their recovery and outcomes monitored, including ICU and hospital stay, postoperative labs, and survival within 30 days",[160,161,162,163,164,27],"Cardiopulmonary Bypass","Coronary Artery Bypass","Heart Valve Diseases","Echocardiography","Intraoperative Complications","2026-02-01",{"date":167,"type":44},"2026-02-05",{"date":167,"type":21},{"date":170,"type":21},"2026-08-30",{"name":172,"class":173},"Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital","OTHER_GOV",{"id":175,"slug":176,"hasResults":11,"nctId":177,"briefTitle":178,"officialTitle":179,"acronym":180,"eligibilityCriteria":181,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":182,"targetDuration":4,"studyType":61,"phases":184,"briefSummary":185,"conditions":186,"keywords":190,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":148},"100619406","guard-ph-guided-use-of-ai-ecg-for-risk-detection-of-ph-in-surgery-guard-ph-trial-100619406","NCT07344207","GUARD-PH: Guided Use of AI-ECG for Risk Detection of PH in Surgery (GUARD-PH Trial)","A Prospective, Open-Label, Randomized Controlled Trial of an Artificial Intelligence Enabled Electrocardiography System for Preoperative Detection of Pulmonary Hypertension and Related Diseases(GUARD-PH)","GUARD-PH","Inclusion Criteria:\n\n1. Age between 18 and 80 years.\n2. Patients scheduled for non-cardiac surgery under general anesthesia.\n3. Patients who have a scheduled standard preoperative electrocardiogram (ECG).\n4. Patients capable of understanding the study and willing to provide medical records for research purposes, and who have signed the informed consent form.\n\nExclusion Criteria:\n\n1. Patients scheduled for emergency surgery.\n2. Patients who explicitly refuse to participate or withdraw consent.\n3. Patients with specific comorbidities that interfere with ECG interpretation or data collection (e.g., implanted pacemakers).",{"count":183,"type":21},1380,[63],"This study is a prospective, open-label, randomized controlled trial designed to evaluate a new artificial intelligence (AI) tool for heart monitoring. Researchers will use an AI-enabled electrocardiography (ECG) system to screen patients before they undergo surgery. The main goal is to determine if this AI system can accurately detect pulmonary hypertension and related heart diseases in the preoperative setting. The study is being conducted at Taipei Veterans General Hospital.",[187,188,27,189],"Pulmonary Hypertension (Diagnosis)","Pre-operative Assessment","Treatment Outcomes",[191,192,193,194,195],"Artificial Intelligence","Electrocardiography","AI-ECG","Preoperative Detection","Screening","2026-01-07",{"date":198,"type":44},"2026-01-15",{"date":200,"type":21},"2026-01-05",{"date":202,"type":21},"2027-01-05",{"name":204,"class":173},"Taipei Veterans General Hospital, Taiwan",{"id":206,"slug":207,"hasResults":11,"nctId":208,"briefTitle":209,"officialTitle":210,"acronym":211,"eligibilityCriteria":212,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":213,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":215,"conditions":216,"keywords":221,"overallStatus":107,"whyStopped":4,"lastUpdateSubmitDate":233,"lastUpdatePostDateStruct":234,"startDateStruct":236,"completionDateStruct":238,"leadSponsor":240,"locationsCount":148},"100594393","feasibility-study-of-novice-performed-lung-ultrasound-for-pneumothorax-detection-after-cardiac-surgery-100594393","NCT07018856","Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery","The CLEAR Vanguard Feasibility Study: Comparative Evaluation of Novice-Performed Lung Ultrasound Versus Chest X-Ray for Pneumothorax Detection Post-Chest Tube Removal in Cardiac Surgery Patients","CLEARVGRD","Inclusion Criteria:\n\n* Age 18 years or older\n* Undergoing cardiac surgery\n* Scheduled for chest and\u002For mediastinal chest tube removal in the cardiovascular intensive care unit (CVICU)\n\nExclusion Criteria:\n\n* Severe chronic lung disease that may impair lung ultrasound interpretation, including:\n* Subcutaneous emphysema\n* COPD or emphysema with FEV₁ \\\u003C 50% predicted\n* Interstitial lung disease with FEV₁ \\\u003C 75% predicted\n* Documented history of pneumothorax prior to chest tube removal requiring intervention\n* Mechanical ventilation at the time of eligibility screening\n* Inability to undergo lung ultrasound or chest X-ray (e.g., due to hemodynamic instability or positioning limitations)",{"count":214,"type":21},120,"What is the purpose of this study? This study is being done to find out if medical trainees (such as residents and fellows) can learn to use lung ultrasound to detect a collapsed lung (pneumothorax) after heart surgery.\n\nWho is participating in the study? Adults who have recently had heart surgery and are having their chest tubes removed in the intensive care unit may be able to join.\n\nWhat will happen during the study? After chest tubes are removed, a trained medical trainee will use a small ultrasound device to check the lungs at the bedside. The patient will also have a chest X-ray, which is the usual test. The results from the ultrasound will be compared to the chest X-ray and reviewed by expert doctors.\n\nWhat is the goal of the study? The goal is to see if it is possible to train medical trainees to use lung ultrasound safely and accurately in real hospital settings. The results will help plan a larger study in the future.",[217,218,219,220,27],"Pneumothorax","Cardiac Surgery","Lung Ultrasound","Chest Tube Removal",[219,222,220,218,223,224,225,226,227,228,229,230,231,232],"Pneumothorax Detection","Point-of-Care Ultrasound","Postoperative Complication","Bedside Ultrasound","Novice Sonographer","Diagnostic Accuracy","Feasibility Study","Critical Care Ultrasound","Trainee-Performed Ultrasound","Chest X-Ray","Medical Education","2025-12-17",{"date":235,"type":44},"2025-12-24",{"date":237,"type":44},"2025-09-16",{"date":239,"type":21},"2027-02",{"name":241,"class":51},"Jacobo Moreno Garijo",{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":248,"eligibilityCriteria":249,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":250,"targetDuration":252,"studyType":22,"phases":4,"briefSummary":253,"conditions":254,"keywords":256,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":267,"completionDateStruct":268,"leadSponsor":270,"locationsCount":4},"100613253","tracheal-cuff-pressure-and-postoperative-complications-a-prospective-observational-study-100613253","NCT07264179","Tracheal Cuff Pressure and Postoperative Complications: A Prospective Observational Study.","Tracheal Cuff Pressure and Postoperative Complications: Prospective Observational Study.","TCP-POC","Inclusion Criteria:\n\n* Age greater than 18 years.\n* Patients scheduled for elective procedures requiring general anesthesia and orotracheal intubation.\n\nExclusion Criteria:\n\n* Age less than 18 years.\n* Refusal to participate in the study.\n* Surgeries performed on an urgent or emergency basis.\n* Surgeries in pregnant women.\n* Cardiac surgeries.\n* Surgeries requiring single-lung ventilation.\n* Head and neck surgeries.\n* Surgeries on the cervical segment of the dorsal spine.\n* Surgeries requiring lateral or prone positioning.\n* Anticipated difficult airway (unanticipated difficult airways will be included).\n* Insufficient fasting time.\n* Surgeries in patients admitted to intensive care units.\n* Patients presenting the same symptoms included in the outcomes to be measured (pre-existing hoarseness, pain, cough, hemoptysis).\n* Tracheostomized patients or those with previous tracheobronchial segment lesions.",{"count":251,"type":21},362,"30 Days","This prospective observational study aims to identify risk factors for tracheal mucosal injuries caused by orotracheal tube use during the intraoperative period in patients undergoing elective surgeries at the Hospital de Clínicas de Porto Alegre. The study will recruit patients sequentially for elective procedures requiring general anesthesia and orotracheal intubation. Primary outcomes include symptoms such as hoarseness, pharyngolaryngeal pain, cough, and hemoptysis, assessed up to 30 days post-surgery. A risk score for tracheal injuries will be derived.",[255,27],"Tracheal Intubation",[257,258,259,260,261,262,263],"Tracheal cuff pressure","Tracheal mucosal lesions","Cough","Orotracheal tube","Postoperative hoarseness","Pharyngolaryngeal pain","Hemoptysis","2025-11-24",{"date":266,"type":44},"2025-12-04",{"date":200,"type":21},{"date":269,"type":21},"2029-04-30",{"name":271,"class":51},"Hospital de Clinicas de Porto Alegre"]