[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postoperative-gastrointestinal-dysfunction-pogd\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postoperative-gastrointestinal-dysfunction-pogd":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100603215","the-effect-of-transcutaneous-electrical-acupoint-stimulation-on-postoperative-gastrointestinal-dysfunction-after-urological-laparoscopic-surgery-100603215",false,"NCT07133620","the Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Gastrointestinal Dysfunction After Urological Laparoscopic Surgery","The Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Gastrointestinal Dysfunction After Urological Laparoscopic Surgery","Inclusion Criteria:\n\n* Age \\> 18 years\n* BMI \\\u003C 28 kg\u002Fm2\n* ASA classification is I-III grade\n* Laparoscopic urological procedures under general anesthesia, including but not limited to laparoscopic nephrectomy and laparoscopic radical prostatectomy for prostate cancer\n* Normal comprehension ability, and the patient or his\u002Fher family members can cooperate in filling out the questionnaire\n* Voluntary to sign the informed consent form\n\nExclusion Criteria:\n\n* Comprehensive assessment of severe cardiovascular, pulmonary and cerebrovascular diseases (such as severe coronary heart disease, valve diseases, respiratory failure, cerebral hemorrhage, cerebral infarction, etc.)\n* Preoperative use of analgesic and gastrointestinal motility drugs\n* TEAS contraindications (having electronic devices in the body, skin damage or infection at the stimulation site)\n* Previous history of TEAS or electro-acupuncture treatment\n* Previous history of gastrointestinal surgery, long-term gastrointestinal motility disorders and severe intestinal diseases\n* Pregnancy","ALL","18 Years",{"count":19,"type":20},112,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this clinical trial is to understand the effect of percutaneous acupoint electrical stimulation on postoperative gastrointestinal dysfunction. It will also investigate the safety of percutaneous acupoint electrical stimulation. The main questions that this trial aims to answer are:\n\nCan percutaneous acupoint electrical stimulation alleviate postoperative gastrointestinal dysfunction? Through which mechanisms do they function?\n\nParticipants will:\n\nPreoperatively, patients were either given or not given percutaneous acupoint electrical stimulation.\n\nRecord their symptoms and biological indicators within 5 days after the operation.",[26],"Postoperative Gastrointestinal Dysfunction (POGD)","RECRUITING","2026-06-22",{"date":30,"type":31},"2026-06-24","ACTUAL",{"date":33,"type":31},"2025-11-01",{"date":35,"type":20},"2026-11-30",{"name":37,"class":38},"The First Affiliated Hospital of Xiamen University","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":21,"phases":50,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":4},"100613844","phase-3-neuromuscular-blocking-agents-on-gastrointestinal-function-following-colorectal-surgery-100613844","NCT07271875","Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal Surgery","Effect of Neuromuscular Reversal With Neostigmine\u002FAtropine Versus Sugammadex on Postoperative Gastrointestinal Function Recovery Following Colorectal Surgery","Inclusion Criteria:\n\n* Age ≥ 18 years\n* American Society of Anesthesiologists (ASA) physical status classification I-III\n* Preoperative Mini-Mental State Examination (MMSE) score \\> 23\n* Patients scheduled for elective colorectal surgery under general anesthesia. Disease diagnoses include colorectal cancer, benign polyps, benign strictures, or diverticular disease.\n* Provide informed consent\n\nExclusion Criteria:\n\n* Presence of psychiatric disorders, cognitive impairment, or language communication barriers that may affect assessment compliance.\n* Body Mass Index (BMI) ≥ 35 kg\u002Fm².\n* Severe hepatic dysfunction (Child-Pugh Class C) or renal dysfunction (estimated glomerular filtration rate \\\u003C 30 ml\u002Fmin\u002F1.73m² and\u002For receiving renal replacement therapy).\n* Pre-existing severe gastrointestinal dysfunction (e.g., intestinal obstruction, active inflammatory bowel disease, severe constipation\u002Fdiarrhea); receipt of neoadjuvant therapy preoperatively; planned stoma creation surgery; or scheduled for low rectal surgery (e.g., low anterior resection, abdominoperineal resection).\n* History of neuromuscular disorders (e.g., myasthenia gravis) or malignant hyperthermia.\n* History of opioid abuse, or chronic non-surgical pain requiring long-term analgesic therapy.\n* Anticipated difficult airway, or patients planned for postoperative transfer to the intensive care unit (ICU) while intubated.\n* Contraindications to the use of neostigmine, atropine, sugammadex, or rocuronium (e.g., known drug allergy, epilepsy, unstable angina, asthma, glaucoma, uncontrolled malignant arrhythmias especially atrioventricular block, severe cardiac valve stenosis); or current use of medications that may significantly influence the effects of neuromuscular blocking agents (e.g., antibiotics such as tetracyclines, aminoglycosides, polymyxins, and clindamycin; antiepileptic drugs; lithium; certain antidepressants such as sertraline and amitriptyline).\n* Pregnant or lactating women.\n* Current participation in other clinical trials that may interfere with the results of this study.","100 Years",{"count":49,"type":20},560,[51],"PHASE3","This study is a clinical research project conducted at Xijing Hospital to compare the effects of two different neuromuscular blockade reversal strategies on the recovery of gastrointestinal (GI) function after colorectal surgery.\n\nMany patients experience slow recovery of bowel function after colorectal surgery, which can lead to discomfort, nausea, vomiting, and a longer hospital stay. This study investigates whether using one medication (sugammadex) to reverse muscle relaxants used during anesthesia leads to better and faster recovery of gastrointestinal function compared to a traditional combination of medications (neostigmine with atropine).\n\nThe study will include 560 adults scheduled for elective colorectal surgery. Participants will be randomly assigned to one of two groups to receive either:\n\nSugammadex (2 mg\u002Fkg), OR Neostigmine (30 μg\u002Fkg) + Atropine (15 μg\u002Fkg) The assigned study drug will be given by intravenous injection at the end of surgery, once measurements show the muscle relaxant is starting to wear off. The patients, surgeons, outcome assessors, and statisticians will be blinded.\n\nThe main goal is to see if more patients in one group recover their gastrointestinal function within 72 hours after surgery. Gastrointestinal recovery is strictly defined as both being able to tolerate food\u002Fdrinks without significant nausea\u002Fvomiting AND having passed gas or had a bowel movement.\n\nThe study will also compare many other important outcomes between the groups, including:\n\n1. Time to first passage of gas, first bowel movement, and first toleration of food.\n2. Pain scores and opioid pain medication use.\n3. Rates of nausea and vomiting.\n4. Overall quality of recovery and patient satisfaction.\n5. Length of hospital stay and total hospitalization costs.\n6. Occurrence of complications within 30 days after surgery.\n7. The safety of both reversal strategies will be closely monitored throughout the study by recording any adverse events.\n\nThis research aims to provide high-quality evidence to help anesthesiologists and surgeons choose the best method to reverse muscle relaxation, potentially leading to faster recovery, fewer complications, and a better overall experience for patients undergoing colorectal surgery.",[26,54,55],"Postoperative Ileus","Colorectal Surgery","NOT_YET_RECRUITING","2025-11-26",{"date":59,"type":31},"2025-12-09",{"date":61,"type":20},"2026-01-01",{"date":63,"type":20},"2027-12-31",{"name":65,"class":38},"Xijing Hospital"]