[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postoperative-hypoxemia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postoperative-hypoxemia":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,40,68,86,107,125],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100634896","effect-of-lateral-versus-supine-positions-on-postoperative-hypoxemia-100634896",false,"NCT07545642","Effect of Lateral Versus Supine Positions on Postoperative Hypoxemia","Effect of Lateral Versus Supine Positions on Postoperative Hypoxemia in Patients Undergoing Painless Gastroscopy and Colonoscopy: A Prospective Randomized Controlled Study","Inclusion Criteria:\n\n1. Age ≥ 18 years.\n2. Both sexes.\n3. American Society of Anesthesiologists (ASA) physical status classification I-III.\n4. Scheduled for combined painless esophagogastroduodenoscopy\u002Fcolonoscopy or either of the two procedures.\n5. Ability to understand the study protocol and provide written informed consent.\n6. A broad set of inclusion criteria was adopted to enroll a patient population that better reflects routine clinical practice. The study aimed to enhance the generalizability of the findings by including patients with various comorbidities, such as preprocedural hypoxemia (room-air SpO₂ ≤ 90%), history of pulmonary surgery, obstructive sleep apnea (OSA), and other pulmonary conditions (including asthma, COPD, chronic bronchitis, emphysema, and pulmonary bullae).\n\nExclusion Criteria:\n\n1. Severe cardiovascular or cerebrovascular diseases.\n2. Pregnant patients.\n3. History of hypersensitivity to ciprofol.\n\nWithdrawal Criteria:\n\n1. Endotracheal intubation required during the procedure.\n2. Voluntary withdrawal requested by the patient or their legal representative.","ALL","18 Years",{"count":19,"type":20},960,"ESTIMATED","INTERVENTIONAL",[23],"NA","Using prospective real-world data, this study aims to determine whether the lateral decubitus position reduces the incidence of post-procedure hypoxemia in patients undergoing painless gastroscopy\u002Fcolonoscopy, thereby providing a simple, non-invasive, and low-cost optimization strategy for clinical practice.",[26],"Postoperative Hypoxemia","RECRUITING","2026-06-22",{"date":30,"type":31},"2026-06-24","ACTUAL",{"date":33,"type":31},"2026-04-22",{"date":35,"type":20},"2026-07-30",{"name":37,"class":38},"General Hospital of Ningxia Medical University","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":4},"100642290","transnasal-microstream-etco2-reduces-hypoxemia-during-emergence-in-aged-post-abdomen-surgery-100642290","NCT07652385","Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen Surgery","Effect of Transnasal Microstream Capnography on Incidence of Hypoxemia During Emergence From General Anesthesia in Elderly Patients After Abdominal Surgery: A Prospective Randomised Controlled Trial","Inclusion Criteria:\n\n* Age 65-80 years;\n* ASA physical status I-III;\n* BMI 18-30 kg\u002Fm²;\n* Participants scheduled for elective laparoscopic surgery under general anesthesia with endotracheal intubation;\n* Willing to participate in the study and provide written informed consent\n\nExclusion Criteria:\n\n* Patients with nasal bleeding, nasal mucosal injury, nasal cavity occupancy, or other conditions that preclude transnasal carbon dioxide monitoring;\n* Patients undergoing emergency surgery;\n* Participants requiring postoperative assisted ventilation via endotracheal intubation or tracheostomy;\n* Presence of any disease or condition that may cause abnormal end-tidal carbon dioxide waveforms or abnormal baseline pulse oximetry (e.g., congenital heart disease or chronic lung disease);\n* Severe cardiac insufficiency (≤4 Metabolic Equivalents \\[MetS\\]);\n* Severe renal insufficiency (acute kidney injury \\[AKI\\] or chronic kidney disease \\[CKD\\] stage 4 or higher);\n* Severe hepatic insufficiency (Child-Pugh class C or worse);\n* Allergy to study medications;\n* Daily alcohol intake ≥60 grams;\n* History of psychiatric disorders such as depression, severe central nervous system depression, Parkinson's disease, basal ganglion lesions, schizophrenia, epilepsy, Alzheimer's disease;\n* Participation in another related clinical study within the past 3 months.",true,"65 Years","80 Years",{"count":51,"type":20},324,[23],"This prospective, randomized controlled study aims to investigate whether transnasal microstream end-tidal carbon dioxide (EtCO₂) monitoring in the post-anesthesia care unit (PACU) reduces the incidence of postoperative hypoxemia in elderly patients (65-80 years, ASA I-III, BMI 18-30 kg\u002Fm²) undergoing elective laparoscopic surgery under general anesthesia with endotracheal intubation. A total of 324 patients will be randomized 1:1 to either the control group (standard SpO₂ monitoring and clinical observation with oxygen delivery at 2 L\u002Fmin via sampling line) or the experimental group (same oxygen delivery plus continuous real-time transnasal microstream EtCO₂ monitoring). The primary outcome is the incidence of hypoxemia (SpO₂ \\\u003C 90% for \\>15 seconds) after extubation in the PACU. Secondary outcomes include severe hypoxemia (SpO₂ \\\u003C 85%), lowest SpO₂ during PACU stay, vital signs at specified time points, PACU length of stay, and other adverse events. Statistical analysis will use chi-square or Fisher's exact test for the primary outcome, with a sample size calculated to detect a reduction in hypoxemia from 33% (control) to 18% (experimental group) (α=0.05, power=80%, plus 20% dropout).",[55,56,26,57],"Elderly Patients","Laparoscopic Surgery","Capnography","NOT_YET_RECRUITING","2026-06-16",{"date":61,"type":31},"2026-06-17",{"date":63,"type":20},"2026-07-01",{"date":65,"type":20},"2028-10-01",{"name":67,"class":38},"Jianbo Wu",{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":21,"phases":76,"briefSummary":77,"conditions":78,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":39},"100641503","effect-of-different-body-positions-on-hypoxemia-during-recovery-in-patients-undergoing-painless-gastroscopy-and-colonoscopy-100641503","NCT07587970","Effect of Different Body Positions on Hypoxemia During Recovery in Patients Undergoing Painless Gastroscopy and Colonoscopy","Effects of Lateral Decubitus Head-up Position, Supine Head-up Position, and Standard Lateral Decubitus Position on Hypoxemia During Recovery in Patients Undergoing Painless Gastroscopy and Colonoscopy: A Multicenter, Three-arm Randomized Controlled Trial",{"count":75,"type":20},1617,[23],"Through a multicenter, three-arm randomized controlled trial design, this study aimed to compare the effects of three positioning strategies-side-lying with elevated head position, supine with elevated head position, and standard side-lying position-on the incidence of hypoxemia during the recovery phase in patients undergoing painless gastroscopy and colonoscopy. The goal was to provide clinicians with a simple, non-invasive, and cost-effective optimization strategy.",[26],"2026-06-15",{"date":61,"type":31},{"date":82,"type":31},"2026-05-08",{"date":84,"type":20},"2027-01-31",{"name":37,"class":38},{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":93,"targetDuration":4,"studyType":95,"phases":4,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":39},"100623819","postoperative-spofio-ratio-and-analgesic-methods-in-laparoscopic-surgery-100623819","NCT07401589","Postoperative SpO₂\u002FFiO₂ Ratio and Analgesic Methods in Laparoscopic Surgery","Association of Postoperative SpO₂\u002FFiO₂ Ratio With Body Mass Index, STOP-BANG Score, and Analgesic Methods in Patients Undergoing Laparoscopic Surgery in Reverse Trendelenburg Position","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patients who provide written informed consent\n* ASA physical status I-III\n* Patients undergoing elective laparoscopic cholecystectomy\n* Surgery performed in the reverse Trendelenburg position (30°)\n* Expected operative duration \\\u003C 3 hours\n* Exclusion Criteria:\n* Age \\\u003C 18 years\n* Refusal or inability to provide informed consent\n* ASA physical status IV or higher\n* Known chronic respiratory diseases (e.g., asthma, COPD)\n* Severe cardiac failure (NYHA class III-IV) or advanced cardiovascular disease\n* Emergency surgery\n* Preoperative oxygen supplementation or baseline SpO₂ \\\u003C 90%\n* Prolonged intubation or perioperative respiratory complications\n* Requirement for postoperative noninvasive ventilation or intensive care unit admission\n* Missing SpO₂ or FiO₂ data preventing calculation of the SpO₂\u002FFiO₂ ratio",{"count":94,"type":20},100,"OBSERVATIONAL","This prospective observational study aims to evaluate the association between postoperative oxygenation, assessed by the SpO₂\u002FFiO₂ ratio, and body mass index (BMI), STOP-BANG score, and postoperative analgesic methods in patients undergoing elective laparoscopic cholecystectomy in the reverse Trendelenburg position. Postoperative SpO₂ and FiO₂ values will be recorded within the first postoperative hour, and the SpO₂\u002FFiO₂ ratio will be calculated. Analgesic techniques applied as part of routine clinical practice will be documented. The study does not involve any additional intervention beyond standard care. The findings are expected to contribute to a better understanding of factors associated with early postoperative oxygenation and hypoxemia risk.",[26],"2026-02-03",{"date":100,"type":31},"2026-02-10",{"date":102,"type":20},"2026-02-15",{"date":104,"type":20},"2026-03-31",{"name":106,"class":38},"Istinye University",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":114,"targetDuration":4,"studyType":95,"phases":4,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":122,"leadSponsor":124,"locationsCount":39},"100619398","preoperative-rox-index-for-predicting-early-postoperative-hypoxemia-in-ent-surgery-100619398","NCT07344103","Preoperative ROX Index for Predicting Early Postoperative Hypoxemia in ENT Surgery","Association of the Preoperative ROX Index With Early Postoperative Hypoxemia in Adult Patients Undergoing Elective Septorhinoplasty and Endoscopic Sinus Surgery: A Prospective Observational Study","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Scheduled for elective septorhinoplasty or endoscopic sinus surgery\n* Undergoing surgery under general anesthesia\n* Ability to undergo preoperative measurement of oxygen saturation and respiratory rate on room air\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 years or \\>65 years\n* ASA physical status III or higher\n* Known severe cardiopulmonary disease (e.g., advanced chronic obstructive pulmonary disease, pulmonary hypertension, severe heart failure)\n* Active respiratory tract infection in the preoperative period\n* Body mass index (BMI) \\>35 kg\u002Fm²\n* Requirement for long-term supplemental oxygen therapy\n* Refusal or inability to provide informed consent",{"count":115,"type":20},80,"Early postoperative hypoxemia is a frequent complication after elective ear, nose, and throat (ENT) surgery and may adversely affect recovery in the post-anesthesia care unit (PACU). Simple and non-invasive preoperative tools to identify patients at risk for early postoperative hypoxemia are limited.\n\nThe ROX index, calculated using oxygen saturation, fraction of inspired oxygen, and respiratory rate, is an easily applicable bedside parameter that has been shown to predict respiratory deterioration in various clinical settings. However, its predictive value in the preoperative period for patients undergoing elective ENT surgery has not been well established.\n\nThis prospective observational study aims to evaluate the association between the preoperative ROX index measured on room air and early postoperative hypoxemia in adult patients undergoing elective septorhinoplasty or endoscopic sinus surgery under general anesthesia. Early postoperative hypoxemia will be defined as oxygen saturation below 92% or the need for supplemental oxygen at a flow rate of 4 L\u002Fmin or higher within the first 30 minutes after PACU admission. The predictive performance of the ROX index will be assessed using receiver operating characteristic (ROC) analysis.",[26],"2026-01-15",{"date":120,"type":31},"2026-01-20",{"date":118,"type":20},{"date":123,"type":20},"2026-04-01",{"name":106,"class":38},{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":130,"acronym":4,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":132,"targetDuration":4,"studyType":21,"phases":134,"briefSummary":135,"conditions":136,"keywords":138,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":148,"locationsCount":4},"100605384","effect-of-postural-changes-on-postoperative-hypoxemia-100605384","NCT07161817","Effect of Postural Changes on Postoperative Hypoxemia","Effect of Semirecumbent and Lateral Positioning on Postoperative Hypoxemia : a Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18 or above and 80 or below who received general anesthesia and intubation\n\nExclusion Criteria:\n\nInclusion criteria:\n\n\\- Patients aged 18 years and above, and 80 years and below, who received general anesthesia and intubation;\n\nExclusion criteria:\n\n* Presence of hypotension or bradycardia upon entering the anesthesia recovery room;\n* Preoperative hypoxemia;\n* Surgical procedures where body position adjustment is not possible or is prohibited due to the nature of the surgery;\n* Surgical procedures involving severe cardiovascular or cerebrovascular diseases, severe pulmonary diseases, intracranial hypertension, etc.;\n* Intubation more than 3 times.",{"count":133,"type":20},1200,[23],"The goal of this clinical trial is to learn which positioning strategy works better to prevent postoperative hypoxemia in surgical patients: semirecumbent positioning or lateral positioning. It will also learn about the safety and effectiveness of these two positioning approaches. The main questions it aims to answer are:\n\nDoes semirecumbent positioning reduce the incidence of postoperative hypoxemia more effectively than lateral positioning? Does lateral positioning reduce the incidence of postoperative hypoxemia more effectively than semirecumbent positioning? What are the differences in patient comfort and recovery outcomes between these two positioning strategies? Researchers will compare semirecumbent positioning directly to lateral positioning to see which approach is more effective in preventing postoperative hypoxemia.\n\nParticipants will:\n\nBe randomly assigned to either semirecumbent positioning or lateral positioning after surgery Have their oxygen levels and breathing monitored regularly during the postoperative period Receive standard post-surgical care with their assigned positioning strategy Be assessed for comfort levels and any positioning-related complications Have their recovery progress tracked throughout their hospital stay.",[26,137],"Position Differences",[139,140,141],"Lateral positioning","Hypoxemia","Semirecumbent positioning","2026-01-13",{"date":144,"type":31},"2026-01-14",{"date":146,"type":20},"2026-02-01",{"date":65,"type":20},{"name":149,"class":38},"Yuhu Ma"]