[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postoperative-pneumonia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postoperative-pneumonia":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,54,89],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100638373","effect-of-positioning-and-acbt-on-pulmonary-complications-after-cardiac-surgery-100638373",false,"NCT07612033","Effect of Positioning and ACBT on Pulmonary Complications After Cardiac Surgery","Effect of Positioning Combined With Active Cycle of Breathing Techniques on Pulmonary Complications After Cardiac Surgeries","P-ACBT","Inclusion Criteria:\n\n* Adult patients (aged from 20 years to 65 years old).\n* Undergoing elective cardiac surgery (Coronary Artery bypass Grafting (CABG) or valves surgeries) via median sternotomy.\n* Hemodynamically stable postoperatively (no high-dose vasopressor support).\n* Fully conscious and capable of following complex verbal instructions.\n\nExclusion Criteria:\n\n* • Patients undergoing emergency cardiac surgery.\n\n  * History of chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD), bronchial asthma, or bronchiectasis\n  * Pre-existing pulmonary complications (e.g., pneumonia, atelectasis, pleural effusion) prior to surgery\n  * Neuromuscular disorders affecting respiratory muscles\n  * Severe obesity (e.g., BMI ≥35 kg\u002Fm²)\n  * Cognitive impairment or inability to follow instructions\n  * Any contraindication to physiotherapy techniques (e.g., unstable sternum, severe pain not controlled)","ALL","20 Years","65 Years",{"count":21,"type":22},124,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this quasi-experimental clinical trial is to learn if position management combined with the Active Cycle of Breathing Techniques (ACBT) works to reduce postoperative pulmonary complications in adult patients undergoing elective cardiac surgery. It will also evaluate the individual effects of each technique compared to routine care.\n\nThe main questions it aims to answer are:\n\nDoes the combination of positioning and ACBT significantly lower the incidence and severity of postoperative pulmonary complications (like atelectasis, pneumonia, and respiratory failure) within the first 7 days after surgery? Does the combination of these techniques reduce the length of hospital stay compared to using each technique alone or routine care? Does the application of ACBT alone lower the rate of respiratory infections? Does position management alone improve oxygenation parameters (such as SpO\\_{2} and PaO\\_{2})?\n\nResearchers will compare four groups of patients to determine the most effective nursing approach:\n\nGroup 1 (Control Group): Participants will receive routine postoperative hospital care only.\n\nGroup 2 (ACBT Group): Participants will perform the Active Cycle of Breathing Techniques (breathing control, thoracic expansion, and huffing) three times daily for 10-15 minutes over 5 postoperative days.\n\nGroup 3 (Positioning Group): Participants will receive structured position management exclusively, shifting from head elevation (30-45) early after surgery to a semi-recumbent position (approx60) during waking hours, alongside other positions like lateral or forward-leaning as tolerated.\n\nGroup 4 (Combined Group): Participants will receive both structured position management and perform the ACBT sessions according to the same schedules.\n\nAll participants will undergo daily respiratory assessments using a standardized scoring system for 7 days post-surgery or until hospital discharge.",[28,29,30,31],"Postoperative Pulmonary Complications (PPCs)","Cardiac Surgery With Sternotomy","Atelectasis","Postoperative Pneumonia",[33,34,35,36,37,38,39,40],"Position management","Active Cycle of Breathing Techniques ACBT","Postoperative pulmonary complications (PPCs)","Cardiac surgery (Open heart surgery)","Median sternotomy","Respiratory rehabilitation","Atelectasis prevention","Nursing-driven intervention","NOT_YET_RECRUITING","2026-05-21",{"date":44,"type":45},"2026-05-28","ACTUAL",{"date":47,"type":22},"2026-06-15",{"date":49,"type":22},"2027-01-01",{"name":51,"class":52},"Assiut University","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":17,"minAge":61,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":23,"phases":64,"briefSummary":65,"conditions":66,"keywords":76,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":53},"100607313","driving-pressure-during-surgeries-with-high-risk-for-postoperative-pulmonary-complications-100607313","NCT07186933","Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications","Inclusion Criteria\n\n* \\>17 years old\n* Surgery with general anesthesia \\& invasive mechanical ventilation\n* Preoperative ARISCAT score estimation \\>25\n\nExclusion Criteria:\n\n* \\\u003C18 years old\n* Preoperative ARISCAT score estimation \\\u003C26\n* Women during pregnancy or just given birth\n* Other type of anesthesia (Not general)\n* Contraindication of administration of neuromuscular blockade agents.\n* Contraindication of cease of spontaneous ventilation.\n* Mechanical ventilation without endotracheal intubation.\n* Severe heart failure \u002F Severe cardiac arrhythmia.\n* Severe emphysematous lung disease.\n* Patient denial of participation in the trial.",true,"18 Years",{"count":63,"type":22},200,[25],"The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure (ΔP), in relation to the appearance of postoperative pulmonary complications (PPCs) in adult patients who are operated and have higher risk of PPCs.\n\nThe main questions it aims to answer are:\n\n* Is MV with lower ΔP better than conventional PMV in preventing PPCs in patients with higher risk for PPCs?\n* Does MV with lower ΔP decrease hospital stay, Intensive Care Unit (ICU) need and mortality?\n* Does MV with lower ΔP suit better than PMV to lung characteristics and needs intraoperatively?\n\nResearchers will compare MV with the lowest possible Driving Pressure (ΔP) to Protective Mechanical Ventilation (PMV) to see if any of this is more protective than the other concerning PPCs.\n\nAll participants will receive perioperative MV.\n\nHalf of them will receive conventional Protective Mechanical Ventilation (PMV). This will include well known generally protective settings for mechanical ventilation of patients, concerning volumes, pressures, respiratory rate, inspiratory gases and ventilation maneuvers.\n\nThe rest of participants will be ventilated with the lowest possible Driving Pressure (ΔP). This will be similar to PMV in the chosen volumes, respiratory rate, inspiratory gases and ventilation maneuvers. However, the pressure inside lung at the end of expiration, eg Positive End Expiratory Pressure (PEEP), will be not be preset for every patient. Initially, the investigators will perform a maneuver that will quantify each individual's lung characteristics and mechanics. According to this, the investigators will find the exact PEEP that seems to suit each patients lungs most, and use this perioperatively, trying to provide lungs the best conditions every time.\n\nAfter the completion of the operation, all the patients will be screened for PPCs, via arterial blood testing and chest X ray, and the results will be statistically analyzed trying to find if any of the forementioned strategies of mechanical ventilation surpasses the other concerning PPCs appearance. PPCs include atelectasis, respiratory failure, bronchospasm, pleural effusion, pneumonia, aspiration and pneumothorax.\n\nFurthermore hospital stay, ICU need and mortality will be noted. Finally, measurements of perioperative lung pressures, volumes and derived variables will be noted and compared statistically as well.",[67,68,69,70,71,72,31,73,74,75],"Postoperative Pulmonary Atelectasis","Postoperative Pulmonary Complications","Postoperative Respiratory Failure","Postoperative Bronchospasm","Postoperative Pleural Effusion","Postoperative Pneumothorax","Postoperative Aspiration Pneumonitis","Mechanical Power","Driving Pressure",[75,74,30,77,68,69,78],"Pulmonary Complications","Elastic Power","RECRUITING","2026-02-08",{"date":82,"type":45},"2026-02-11",{"date":84,"type":45},"2025-11-03",{"date":86,"type":22},"2027-11-30",{"name":88,"class":52},"University General Hospital of Patras",{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":4,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":17,"minAge":61,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":23,"phases":99,"briefSummary":100,"conditions":101,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":4},"100526691","intravenous-lidocaine-infusion-reduce-postoperative-pulmonary-complications-in-patients-undergoing-minimally-invasive-esophagectomy-100526691","NCT06138041","Intravenous Lidocaine Infusion Reduce Postoperative Pulmonary Complications in Patients Undergoing Minimally Invasive Esophagectomy","Effect of Intravenous Lidocaine Infusion on Postoperative Pulmonary Complications in Patients Undergoing Minimally Invasive Esophagectomy: a Double-center, Double-blind, Randomized Controlled Trial","Inclusion Criteria:\n\nPatients between 18 and 85 years of age with a recent schedule for MIE are screened for this study. Patients who show clear consciousness and ASA status I - III will be included as eligible participants.\n\nExclusion Criteria:\n\nThe exclusion criteria are as follows: patients with severe psychiatric disorders, such as schizophrenia, depression, dementia, etc.; severe hepatic insufficiency (concentration of glutamic oxaloacetic transaminase, glutamic pyruvic transaminase or bilirubin ≥2.5 times the upper limit of normal); renal impairment (creatinine clearance \\\u003C60 mL\u002Fmin); allergy to amide local anesthetics; history of seizures; presence of II\u002FIII atrioventricular block; patients with severe sinus bradycardia or sick sinus syndrome; patients with Adams-Stokes syndrome or pre-excitation syndrome; intracardiac block (e.g. complete bundle branch block, atrioventricular block); serum potassium ion concentration below 2.5 or above 5.0 mmol\u002FL; PH\\>7.55 or PH\\\u003C7.2. Patients will be discontinued if any of the following situations occur: the patient has an allergic reaction, severe cardiovascular events that cannot be managed with symptomatic treatment, and the patient is unwilling to continue the study.","85 Years",{"count":98,"type":22},770,[25],"The goal of this double-center, double-blind, randomized controlled clinical trial is to compare the effect of intravenous lidocaine infusion on postoperative pulmonary complications in patients undergoing minimally invasive esophagectomy. The main question it aims to answer are whether intravenous lidocaine reduce postoperative pulmonary complications in patients undergoing minimally invasive esophagectomy. Participants will be given intravenous lidocaine infusion in lidocaine group or placebo in control group.",[31,67,102],"Postoperative Pulmonary Edema","2024-10-20",{"date":105,"type":45},"2024-10-22",{"date":107,"type":22},"2025-02-01",{"date":109,"type":22},"2025-08-30",{"name":111,"class":52},"Sichuan Cancer Hospital and Research Institute"]