[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postoperative-pulmonary-complications\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postoperative-pulmonary-complications":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,17,0,[8,43,83,109,140,164,192,214,245,271,290,323,352,377,402,432,452],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100644915","hfnc-for-postoperative-atelectasis-after-laparoscopic-surgery-100644915",false,"NCT07676760","HFNC for Postoperative Atelectasis After Laparoscopic Surgery","The Role of High-Flow Nasal Cannula in Monitoring Postoperative Atelectasis With Lung Ultrasonography After Laparoscopic Surgery: A Prospective Observational Study","Inclusion Criteria:\n\n* Adult patients aged 18 years and older\n* Patients scheduled for elective laparoscopic surgery (general surgery, urology, gynecology)\n* Patients undergoing mechanical ventilation under general anesthesia\n* ASA physical status I-III\n* Patients providing written informed consent\n\nExclusion Criteria:\n\n* Severe or uncontrolled chronic obstructive pulmonary disease, asthma, or other chronic pulmonary diseases\n* Patients with atelectasis or pleural effusion detected on preoperative lung ultrasonography\n* Patients requiring intraoperative recruitment maneuver\n* ASA physical status IV or above\n* Patients receiving spinal or epidural anesthesia\n* Cases requiring conversion to laparoscopy or laparotomy\n* Patients refusing to participate","ALL","18 Years",{"count":19,"type":20},90,"ESTIMATED","OBSERVATIONAL","Pneumoperitoneum and Trendelenburg positioning during laparoscopic surgery promote atelectasis development, which has been reported in up to 90% of patients under general anesthesia and increases the risk of postoperative pulmonary complications. High-flow nasal cannula (HFNC) oxygen therapy may reduce post-extubation atelectasis through alveolar recruitment. This prospective observational cohort study aims to evaluate the role of HFNC in postoperative atelectasis monitored by lung ultrasonography (LUS) in patients undergoing elective laparoscopic surgery.",[24,25],"Postoperative Atelectasis","Postoperative Pulmonary Complications",[27,28,24,29,30],"High-Flow Nasal Cannula","Lung Ultrasonography","Laparoscopic Surgery","Pneumoperitoneum","NOT_YET_RECRUITING","2026-06-27",{"date":34,"type":35},"2026-06-30","ACTUAL",{"date":37,"type":20},"2026-07",{"date":39,"type":20},"2027-07",{"name":41,"class":42},"Bursa Yuksek Ihtisas Training and Research Hospital","OTHER_GOV",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":64,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":82},"100641870","brief-bronchial-suction-for-lung-collapse-during-uniportal-vats-100641870","NCT07660588","Brief Bronchial Suction for Lung Collapse During Uniportal VATS","Effect of Brief Bronchial Suction on the Quality of Non-Ventilated Lung Collapse and Time to Adequate Surgical Exposure During Uniportal Video-Assisted Thoracoscopic Surgery: a Randomized Patient- and Surgeon-Blinded Trial","Inclusion Criteria:\n\n* Age ≥ 18 years old\n* BMI ≤ 35 kg\u002Fm2\n* American Society of Anesthesiologists (ASA) physical status I to III\n* Scheduled for elective single-port video-assisted thoracoscopic surgery (VATS) at Siriraj Hospital\n* Requirement for one-lung ventilation using a double-lumen tube (DLT)\n* Surgery performed in the lateral decubitus position\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Previous thoracic surgery\n* Known or suspected severe pleural adhesions based on preoperative imaging or clinical history\n* Tracheobronchial anatomical abnormalities\n* Pulmonary bullae identified on chest radiography or computed tomography, or a history of recurrent pneumothorax\n* Forced vital capacity (FVC) \\\u003C 50% of predicted\n* Pregnancy",true,{"count":52,"type":20},100,"INTERVENTIONAL",[55],"NA","The goal of this clinical trial is to learn whether a brief suction of the airway going to the surgical lung (bronchus) can help the lung collapse faster and more completely during uniportal video-assisted thoracoscopic surgery (UVATS). This type of surgery is performed through a small incision in the chest, and good lung collapse helps the surgeon see and work safely. The main questions it aims to answer are\n\n1. Does brief bronchial suction improve the quality of lung collapse 1 minute after chest cavity is opened?\n2. Does brief bronchial suction help reach satisfactory lung collapse faster?\n\nResearchers will compare patients who receive brief bronchial suction and those who do not. This is to see if suction improves and fastens lung collapse, reduce the need for additional steps if lung is not adequately collapsed, affect inflammation, oxygenation, postoperative pulmonary complications, operative time, and the duration of one-lung ventilation. Participants will\n\n1. Undergo UVATS under general anesthesia\n2. Have a double-lumen breathing tube placed as part of the standard anesthetic care\n3. Be randomly assigned to either receive bronchial suction for one minute or receive no bronchial suction\n4. Have the surgical team assess the quality of lung collapse at different time points\n5. Have blood samples taken for interleukin-6, a marker related to inflammation, once during and once after surgery. These samples are collected through a small tube in a vein that is placed as a standard anesthetic care while the participant is under general anesthesia. No extra puncture is required for blood collection.\n6. Have information collected from the routine anesthesia and surgical records such as oxygen levels during surgery, length of surgery and lung-related complications within 7 days after surgery",[58,59,60,61,62,63,25],"Lung Collapse","One-lung Ventilation","Thoracic Anesthesia","Thoracic Surgery, Video-assisted","Double-lumen Tube","Uniportal Video Assisted Thoracic Surgery (U-VATS)",[65,66,67,68,69,70,71],"uniportal VATS","UVATS","bronchial suction","lung collapse","one-lung ventilation","double-lumen tube","thoracic anesthesia","2026-06-16",{"date":74,"type":35},"2026-06-22",{"date":76,"type":20},"2026-08",{"date":78,"type":20},"2028-07",{"name":80,"class":81},"Mahidol University","OTHER",1,{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":93,"conditions":94,"keywords":97,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":82},"100643112","mechanical-power-and-pulmonary-complications-in-cabg-surgery-100643112","NCT07639489","Mechanical Power and Pulmonary Complications in CABG Surgery","Association of Intraoperative Mechanical Power With Postoperative Pulmonary Complications and Prolonged Mechanical Ventilation in Coronary Artery Bypass Graft Surgery","MP-CABG","Inclusion Criteria:\n\n* Age 18 years or older\n* Scheduled for elective, first-time isolated CABG surgery\n* Use of cardiopulmonary bypass (CPB)\n* Intraoperative mechanical ventilation applied under general anesthesia with recordable ventilator data\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Emergency cardiac surgery\n* Off-pump CABG (without CPB)\n* Preoperative requirement for invasive mechanical ventilation\n* Advanced chronic lung disease\n* Incomplete or unreliable intraoperative ventilatory data\n* Intraoperative use of advanced non-standard support (ECMO)",{"count":92,"type":20},110,"This prospective observational study evaluates the association between intraoperative mechanical power (MP) - a composite measure of the total energy delivered to the lungs during mechanical ventilation - and postoperative pulmonary complications (PPCs) and prolonged mechanical ventilation in adult patients undergoing elective coronary artery bypass graft (CABG) surgery with cardiopulmonary bypass (CPB). Intraoperative ventilatory parameters including tidal volume, respiratory rate, airway pressures, and PEEP will be recorded and used to calculate MP and driving pressure (DP). No additional interventions will be applied beyond standard clinical care.",[25,95,96],"Coronary Artery Bypass Graft Surgery (CABG)","Prolonged Mechanical Ventilation",[98,99],"intraoperative ventilation","lung-protective ventilation","2026-06-06",{"date":102,"type":35},"2026-06-10",{"date":104,"type":20},"2026-06",{"date":106,"type":20},"2026-09",{"name":108,"class":42},"Fusun Gozen",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":53,"phases":119,"briefSummary":120,"conditions":121,"keywords":125,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":4},"100638342","mechanical-power-for-ventilatory-settings-in-operating-room-100638342","NCT07620132","Mechanical Power for Ventilatory Settings in Operating Room","Mechanical Power for Ventilatory Settings in Operating Room: a Multicenter Randomized Controlled Trial","IMPROVEIII","Inclusion Criteria:\n\n* Adult (≥ 18 years)\n* Laparoscopic or non-laparoscopic abdominal surgery\n* With an expected duration of at least 2 hours\n\nExclusion Criteria:\n\n* Patients already receiving mechanical ventilation \\> 12 hours before surgery;\n* Chronic respiratory disease requiring oxygen therapy or mechanical ventilation at home;\n* Undrained pneumothorax or subcutaneous emphysema;\n* Intracranial hypertension;\n* Patients for which death is deemed imminent and inevitable or patients with an underlying disease process with a life expectancy of less than 3 months;\n* Patients already enrolled in the IMPROVE III trial;\n* Pregnancy in progress or planned during the study period or breastfeeding women (Art. L1121-5 of the French Public Health Code);\n* Patients protected by law (Art. L1121-6 to L1121-8 of the French Public Health Code): Individuals deprived of their liberty by judicial or administrative decision, vulnerable persons, minors, adults under guardianship or curatorship;\n* Patients not covered by a French social security scheme and not benefiting from such a scheme;\n* Absence of free and informed oral consent from the patient before inclusion (except in emergency situation where the patient is unable to provide consent), or absence of written informed consent from his\u002Fher proxy if present in an emergency situation (except in life-threatening emergency, where inclusion without consent from the patient or his\u002Fher proxy is permitted), in which case consent will be obtained as soon as possible after inclusion.",{"count":118,"type":20},490,[55],"Postoperative respiratory failure (PRF) is a dreaded complication that imposes a significant burden through unplanned admission to the ICU, post discharge disability and mortality. Despite widespread implementation of intraoperative lung-protective ventilation strategies over the past decade, results remain inconsistent. Interventions targeting individual parameters like tidal volume or positive end-expiratory pressure (PEEP) have shown equivocal results. The use of high PEEP and recruitment maneuvers raises safety concerns by possible negative hemodynamic effects. Recent studies suggest that individualizing ventilation strategies based on mechanical power-a composite parameter integrating tidal volume, plateau pressure, PEEP, and ventilator frequency-may better predict and help prevent PRF, independently of patients' baseline respiratory system compliance. These studies identified this parameter as interventional targets to reduce lung injury during mechanical ventilation. However, no multicenter randomized controlled trial has been performed in the field of ventilatory settings titration during invasive mechanical ventilation in operating room.\n\nThe investigators hypothesize that a ventilation strategy aimed at decreasing mechanical power will reduce the incidence of PRF and mortality in patients undergoing abdominal surgery, compared with a standard strategy using fixed tidal volume and PEEP",[122,123,25,124],"Postoperative Respiratory Failure","Abdominal Surgery","Morality",[126,127,128,129,130],"Mechanical ventilation","Intubation","Mechanical power-guided ventilation","Laparoscopic or non-laparoscopic abdominal surgery","Intensive care unit","2026-05-26",{"date":133,"type":35},"2026-06-02",{"date":135,"type":20},"2026-06-01",{"date":137,"type":20},"2029-01-01",{"name":139,"class":81},"University Hospital, Montpellier",{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":144,"acronym":145,"eligibilityCriteria":146,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":147,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":149,"conditions":150,"keywords":151,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":82},"100499953","preventing-postoperative-pulmonary-complications-by-establishing-a-machine-learning-assisted-approach-100499953","NCT05789953","PrEventing PostoPERative Pulmonary Complications by Establishing a MachINe-learning assisTed Approach","PEPPERMINT","Inclusion Criteria:\n\n* adult patients\n* elective, surgical procedure\n* general anaesthesia\n\nExclusion Criteria:\n\n* patients younger than 18 years of age\n* outpatient surgery\n* postoperative admission to intensive care unit",{"count":148,"type":20},512,"Postoperative pulmonary complications (POPC) are common after general anaesthesia and are a major cause of increased morbidity and mortality in surgical patients. However, prevention and treatment methods for POPC that are considered effective, tie up human and technical resources. The aim of the planned research project is therefore to enable reliable identification of high-risk patients on the basis of a tailored machine learning algorithm using perioperative clinical routine data and sonographic imaging data collected in the recovery room. The randomized clinical trial will include 512 patients undergoing elective surgery in general anaesthesia. The primary outcome will be the development of POPC. The goal of the study is to detect postoperative pulmonary complications before they become clinically manifest.",[25],[152,153],"machine learning","lung ultrasound","RECRUITING","2026-05-04",{"date":157,"type":35},"2026-05-08",{"date":159,"type":35},"2023-04-25",{"date":161,"type":20},"2026-12",{"name":163,"class":81},"Britta Trautwein",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":170,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":172,"enrollmentInfo":173,"targetDuration":4,"studyType":53,"phases":175,"briefSummary":176,"conditions":177,"keywords":179,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":82},"100539510","the-effect-of-continuous-intravenous-infusion-of-lidocaine-on-ppcs-and-prognosis-in-emergency-surgical-patients-with-iai-100539510","NCT06304779","The Effect of Continuous Intravenous Infusion of Lidocaine on PPCs and Prognosis in Emergency Surgical Patients With IAI","The Effect of Continuous Intravenous Infusion of Lidocaine on Postoperative Pulmonary Complications and Prognosis in Emergency Surgical Patients With Intra-abdominal Infection","PPCs","Inclusion Criteria:\n\n* Age \\>18 years, any gender.\n* Patients suspected of digestive tract perforation or obstruction based on physical examination, confirmed by imaging, requiring emergency surgical treatment.\n* The anesthesia method is general anesthesia\n* I or the patient's family have carefully read and signed the informed consent form\n* Serum procalcitonin (PCT) at inflammatory levels or leukocytosis (\\>12×109\u002FL) or leukopenia (\\\u003C4×109\u002FL) or \\>10% naive leukocytes\n\nExclusion Criteria:\n\n* Have a history of local anesthesia drug allergy\n* Pregnant patients\n* Patients receiving renal replacement therapy\n* Patients with arrhythmias or heart failure (second or third-degree atrioventricular block or left ventricular ejection fraction（LVEF）\n* Preoperative platelet count\\\u003C80 × 109\u002FL\n* Patients who require secondary surgery for postoperative anastomotic fistula\n* Patients who have participated in other clinical studies","100 Years",{"count":174,"type":20},428,[55],"The main purpose of this study is to evaluate the impact of continuous 24-hour intravenous infusion of lidocaine on the incidence of PPCs in patients undergoing emergency laparotomy for intra-abdominal infection (IAI).The secondary objectives of this study are to assess the impact of continuous 24-hour intravenous lidocaine infusion on the proportion of patients requiring mechanical ventilation, protection of important organ function during the perioperative period, length of hospital stay, and outcomes within 30 days postoperatively.",[25,178],"Intra-abdominal Infection",[180,181,182],"intra-abdominal infection","lidocaine","postoperative pulmonary complications","2026-04-23",{"date":185,"type":35},"2026-04-29",{"date":187,"type":35},"2023-10-31",{"date":189,"type":20},"2027-11-30",{"name":191,"class":81},"Shanghai Zhongshan Hospital",{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":197,"acronym":4,"eligibilityCriteria":198,"healthyVolunteers":50,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":199,"targetDuration":4,"studyType":53,"phases":201,"briefSummary":202,"conditions":203,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":206,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":212,"locationsCount":4},"100634190","peep-strategies-and-mechanical-power-in-robotic-surgery-100634190","NCT07536464","PEEP Strategies and Mechanical Power in Robotic Surgery","Comparison of Incremental, Decremental, and Fixed PEEP Strategies on Mechanical Power and Postoperative Oxygenation in Robotic Surgery: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Age\\>= 18\n* ASA I-III\n* Elective robotic surgery\n\nExclusion Criteria:\n\n* COPD GOLD ≥2\n\n  * Restrictive lung disease\n  * BMI \\>40 kg\u002Fm²\n  * Heart failure\n  * Preoperative oxygen requirement\n  * Need for postoperative mechanical ventilation\n  * Refusal to participate",{"count":200,"type":20},120,[55],"Robotic surgery requires pneumoperitoneum and steep Trendelenburg positioning, which significantly impair respiratory mechanics and increase the risk of postoperative pulmonary complications.\n\nPositive end-expiratory pressure (PEEP) is a key determinant of lung recruitment; however, fixed PEEP strategies may not be optimal for all patients. Individualized PEEP titration strategies, including incremental and decremental approaches, may better optimize lung mechanics.\n\nThis randomized controlled trial aims to compare the effects of incremental, decremental, and fixed PEEP strategies on cumulative mechanical power (MP-AUC) and postoperative oxygenation in patients undergoing robotic surgery.",[25,204,205],"Impaired Oxygenation","Mechanical Ventilation","2026-04-11",{"date":208,"type":35},"2026-04-17",{"date":210,"type":20},"2026-04-15",{"date":34,"type":20},{"name":213,"class":81},"Ankara City Hospital Bilkent",{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":220,"eligibilityCriteria":221,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":222,"enrollmentInfo":223,"targetDuration":4,"studyType":53,"phases":225,"briefSummary":227,"conditions":228,"keywords":231,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":236,"lastUpdatePostDateStruct":237,"startDateStruct":239,"completionDateStruct":241,"leadSponsor":243,"locationsCount":82},"100631321","phase-4-perioperative-lidocaine-for-lung-protection-in-infants-undergoing-cardiac-surgery-100631321","NCT07499154","Perioperative Lidocaine for Lung Protection in Infants Undergoing Cardiac Surgery","Evaluation of the Effect of Perioperative Lidocaine Administration on Reducing Pulmonary Injury in Infants Following Cardiac Surgery: A Randomized, Placebo-Controlled, Double-Blind, Multi-center Superiority Trial.","PLICS","Inclusion Criteria:\n\n1. Infants aged 0 to 12 months.\n2. Congenital heart disease requiring corrective, non-palliative cardiac surgery with cardiopulmonary bypass.\n3. American Society of Anesthesiologists (ASA) physical status I to III.\n4. Written informed consent provided by parent(s) or legal guardian(s).\n\nExclusion Criteria:\n\n1. Multiple malformations, chromosomal abnormalities, or immunodeficiency.\n2. Known or suspected allergy to lidocaine.\n3. Concomitant continuous infusion of another local anesthetic.\n4. Conditions associated with increased risk of lidocaine accumulation or toxicity, including severe conduction block or severe bradycardia.\n5. ASA physical status IV or higher.\n6. Severe malnutrition expected to substantially impair postoperative recovery.\n7. Severe hepatic or renal dysfunction.\n8. Significant pre-existing pulmonary disease or markedly impaired preoperative pulmonary function.\n9. Central nervous system disorders that may increase susceptibility to lidocaine neurotoxicity, including epilepsy or prior central nervous system infection.\n10. Use of medications that may interact with lidocaine or constitute an exclusion, including class I or class III antiarrhythmic agents, cimetidine, or antiviral drugs, as determined by the clinical team.\n11. Current or recent participation in another interventional clinical trial in its active intervention phase.","12 Months",{"count":224,"type":20},320,[226],"PHASE4","Cardiopulmonary bypass-associated pulmonary injury is a common complication after infant cardiac surgery and may contribute to impaired oxygenation, prolonged mechanical ventilation, and longer intensive care stay. Lidocaine has anti-inflammatory and membrane-stabilizing properties and may attenuate perioperative lung injury. This investigator-initiated, randomized, placebo-controlled, double-blind trial will evaluate whether perioperative intravenous lidocaine reduces postoperative pulmonary injury in infants undergoing corrective non-palliative congenital cardiac surgery with cardiopulmonary bypass.",[229,25,230],"Congenital Heart Disease","Acute Lung Injury",[232,233,234,235],"Lidocaine","Lung injury","Infant cardiac surgery","Cardiopulmonary bypass","2026-03-23",{"date":238,"type":35},"2026-03-30",{"date":240,"type":20},"2026-04-01",{"date":242,"type":20},"2027-12-31",{"name":244,"class":81},"The Children's Hospital of Zhejiang University School of Medicine",{"id":246,"slug":247,"hasResults":11,"nctId":248,"briefTitle":249,"officialTitle":249,"acronym":4,"eligibilityCriteria":250,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":251,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":253,"conditions":254,"keywords":259,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":263,"lastUpdatePostDateStruct":264,"startDateStruct":265,"completionDateStruct":267,"leadSponsor":269,"locationsCount":82},"100630499","quality-improvement-project-to-reduce-preoperative-fasting-times-before-elective-procedures-100630499","NCT07488468","Quality Improvement Project to Reduce Preoperative Fasting Times Before Elective Procedures","Inclusion Criteria:\n\n* All patients elective surgery or intervention requiring with anesthesiology care general anesthesia, regional anesthesia, sedation, or anesthesiology stand-by\n\nExclusion Criteria:\n\n* Already sedated, intubated, and mechanically ventilated patients",{"count":252,"type":20},1000,"This single-center quality improvement project evaluates preoperative fasting times before elective procedures requiring anesthesiology care. The project aims to reduce prolonged fasting for clear fluids by implementing a local standard operating procedure (SOP) allowing patients to drink clear liquids until being called to the operating room (\"drink until called\"), supported by staff education and fasting instruction cards. Fasting times and selected perioperative outcomes will be assessed before and after implementation.",[255,256,257,25,258],"Preoperative Fasting","Perioperative Patient Comfort \u002F Quality of Care","Postoperative Nausea and Vomiting (PONV)","Delirium",[260,261,262],"Preoperative fasting","clear liquids","quality improvement","2026-03-17",{"date":236,"type":35},{"date":266,"type":35},"2026-01-30",{"date":268,"type":20},"2026-07-30",{"name":270,"class":81},"University of Giessen",{"id":272,"slug":273,"hasResults":11,"nctId":274,"briefTitle":275,"officialTitle":276,"acronym":4,"eligibilityCriteria":277,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":278,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":279,"conditions":280,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":288,"locationsCount":82},"100626100","mechanical-power-and-driving-pressure-exposure-in-laparoscopic-surgery-100626100","NCT07431242","Mechanical Power and Driving Pressure Exposure in Laparoscopic Surgery","Time-Dependent Exposure to Intraoperative Mechanical Power and Driving Pressure and Postoperative Pulmonary Outcomes in Laparoscopic Surgery","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Scheduled for elective laparoscopic abdominal surgery under general anesthesia\n* Intraoperative mechanical ventilation with volume-controlled ventilation\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Emergency surgery\n* Conversion to open surgery\n* Preoperative invasive or noninvasive mechanical ventilation\n* Intraoperative major complications requiring substantial deviation from routine ventilation management\n* Incomplete intraoperative or postoperative data\n* Refusal or inability to provide informed consent",{"count":19,"type":20},"Postoperative pulmonary complications (PPCs) remain an important cause of morbidity after abdominal surgery. Intraoperative mechanical ventilation may contribute to lung injury through the mechanical load applied to the respiratory system. Mechanical power (MP) and driving pressure (DP) have emerged as integrative parameters reflecting the total ventilatory burden delivered to the lungs.\n\nThis prospective observational study aims to evaluate the association between time-dependent exposure to intraoperative mechanical power and driving pressure and postoperative pulmonary outcomes in patients undergoing elective laparoscopic abdominal surgery. Ventilatory parameters will be recorded at predefined intervals during routine clinical care, and MP and DP will be calculated without altering clinical management. The primary objective is to assess whether longer exposure to elevated ventilatory load is associated with the development of postoperative pulmonary complications.",[25],"2026-02-18",{"date":283,"type":35},"2026-02-24",{"date":285,"type":20},"2026-02-25",{"date":287,"type":20},"2026-07-15",{"name":289,"class":81},"Istinye University",{"id":291,"slug":292,"hasResults":11,"nctId":293,"briefTitle":294,"officialTitle":295,"acronym":296,"eligibilityCriteria":297,"healthyVolunteers":11,"sex":16,"minAge":298,"maxAge":299,"enrollmentInfo":300,"targetDuration":4,"studyType":53,"phases":302,"briefSummary":303,"conditions":304,"keywords":307,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":315,"lastUpdatePostDateStruct":316,"startDateStruct":318,"completionDateStruct":320,"leadSponsor":321,"locationsCount":82},"100615588","evaluation-of-the-effect-of-perioperative-recruitment-maneuver-practice-on-lung-ultrasound-score-and-mechanical-power-in-pediatric-patients-100615588","NCT07294560","Evaluation of the Effect of Perioperative Recruitment Maneuver Practice on Lung Ultrasound Score and Mechanical Power in Pediatric Patients","Evaluation of the Effect of Perioperative Recruitment Maneuver Practice on Lung Ultrasound Score and Mechanical Power in Pediatric Patients; A Prospective Randomized Study","LUS RM PEEP","Inclusion Criteria:\n\n* Patients aged 1-14 years with\n* ASA score of 1-3\n* who had surgery in the operating rooms of Cerrahpaşa Medical Faculty during the study period\n* surgical duration was at least 2 hours\n\nExclusion Criteria:\n\n* ASA score of 4\n* defined lung disease (patients using medication due to asthma and having 2 emergency visits within 1 year)\n* prematurity (\\\u003C 36 weeks gestational age \u002F bronchopulmonary dysplasia)\n* cystic fibrosis\n* diagnosed syndromic disease\n* congenital cardiac disease\n* abnormal chest X-ray\n* chest wall deformity\n* or history of previous chest surgery","1 Year","14 Years",{"count":301,"type":20},78,[55],"Pulmonary atelectasis is common during general anesthesia and increases the risk of hypoxemia, especially in pediatric patients. PEEP and recruitment maneuvers (RM) are effective in preventing atelectasis. Lung ultrasound is practical for diagnosis. Mechanical power refers to the amount of energy delivered to the lung by the ventilator; excessive mechanical power can cause lung injury. Limiting mechanical power may reduce postoperative complications. This study aimed to determine the effectiveness of recruitment maneuvers in preventing atelectasis using lung ultrasound during the intraoperative period, to examine the relationship between lung ultrasound scores and mechanical power, and to demonstrate the effect of recruitment maneuvers on postoperative pulmonary complications. This study is based on the hypothesis that \"The recruitment maneuver reduces perioperative atelectasis and the development of related complications, and lung ultrasound can be used to detect this. The lung ultrasound score also decreases in patients with reduced mechanical force.\" It will be prospectively applied to pediatric patients aged 1-14 years who will undergo surgery in the operating rooms of Cerrahpaşa Medical Faculty.\n\nPatients included in the study will be prospectively randomized into 3 groups. The randomization performed using the sealed opaque envelope method.All patients will be ventilated in VG-Pressure guaranteed mode. Tidal volume will be calculated as 6-8 ml\u002Fkg of ideal body weight.\n\nGROUP 1: Fixed PEEP: 5 cmH2O, GROUP 2: PEEP: 5 cmH2O, 5 cycles, recruitment maneuver with plateau P\\\u003C35 cm H2O and vital capacity x2. GROUP 3: PEEP: 5 cmH2O, 5 cycles of recruitment maneuvers will be performed in the right and left lateral decubitus position before extubation with P\\\u003C35 cmH2O and vital capacity x2.\n\nLung ultrasound will be performed before induction (1), 5 minutes after intubation (2), before extubation (3), and finally 5 minutes after extubation(4). Each hemithorax will be divided into 6 regions, and lung scores will be recorded. At 5 minutes after intubation and every hour there after, PeakP, PlateauP, DeltaP, Compliance, Driving Pressures, and Mechanical Work calculations will be recorded before and after the maneuver in the group undergoing the recruitment maneuver.",[25,305,306],"Postoperative Pulmonary Atelectasis","Pediatric Surgery",[308,309,310,311,312,313,314],"recruitment maneuver","pediatric recruitment maneuver","PEEP","mechanical power","mechanical work","compliance","atelectasis","2026-02-09",{"date":317,"type":35},"2026-02-11",{"date":319,"type":20},"2026-02-15",{"date":287,"type":20},{"name":322,"class":81},"Istanbul University - Cerrahpasa",{"id":324,"slug":325,"hasResults":11,"nctId":326,"briefTitle":327,"officialTitle":327,"acronym":4,"eligibilityCriteria":328,"healthyVolunteers":50,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":329,"targetDuration":4,"studyType":53,"phases":331,"briefSummary":332,"conditions":333,"keywords":341,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":345,"lastUpdatePostDateStruct":346,"startDateStruct":347,"completionDateStruct":349,"leadSponsor":350,"locationsCount":82},"100607313","driving-pressure-during-surgeries-with-high-risk-for-postoperative-pulmonary-complications-100607313","NCT07186933","Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications","Inclusion Criteria\n\n* \\>17 years old\n* Surgery with general anesthesia \\& invasive mechanical ventilation\n* Preoperative ARISCAT score estimation \\>25\n\nExclusion Criteria:\n\n* \\\u003C18 years old\n* Preoperative ARISCAT score estimation \\\u003C26\n* Women during pregnancy or just given birth\n* Other type of anesthesia (Not general)\n* Contraindication of administration of neuromuscular blockade agents.\n* Contraindication of cease of spontaneous ventilation.\n* Mechanical ventilation without endotracheal intubation.\n* Severe heart failure \u002F Severe cardiac arrhythmia.\n* Severe emphysematous lung disease.\n* Patient denial of participation in the trial.",{"count":330,"type":20},200,[55],"The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure (ΔP), in relation to the appearance of postoperative pulmonary complications (PPCs) in adult patients who are operated and have higher risk of PPCs.\n\nThe main questions it aims to answer are:\n\n* Is MV with lower ΔP better than conventional PMV in preventing PPCs in patients with higher risk for PPCs?\n* Does MV with lower ΔP decrease hospital stay, Intensive Care Unit (ICU) need and mortality?\n* Does MV with lower ΔP suit better than PMV to lung characteristics and needs intraoperatively?\n\nResearchers will compare MV with the lowest possible Driving Pressure (ΔP) to Protective Mechanical Ventilation (PMV) to see if any of this is more protective than the other concerning PPCs.\n\nAll participants will receive perioperative MV.\n\nHalf of them will receive conventional Protective Mechanical Ventilation (PMV). This will include well known generally protective settings for mechanical ventilation of patients, concerning volumes, pressures, respiratory rate, inspiratory gases and ventilation maneuvers.\n\nThe rest of participants will be ventilated with the lowest possible Driving Pressure (ΔP). This will be similar to PMV in the chosen volumes, respiratory rate, inspiratory gases and ventilation maneuvers. However, the pressure inside lung at the end of expiration, eg Positive End Expiratory Pressure (PEEP), will be not be preset for every patient. Initially, the investigators will perform a maneuver that will quantify each individual's lung characteristics and mechanics. According to this, the investigators will find the exact PEEP that seems to suit each patients lungs most, and use this perioperatively, trying to provide lungs the best conditions every time.\n\nAfter the completion of the operation, all the patients will be screened for PPCs, via arterial blood testing and chest X ray, and the results will be statistically analyzed trying to find if any of the forementioned strategies of mechanical ventilation surpasses the other concerning PPCs appearance. PPCs include atelectasis, respiratory failure, bronchospasm, pleural effusion, pneumonia, aspiration and pneumothorax.\n\nFurthermore hospital stay, ICU need and mortality will be noted. Finally, measurements of perioperative lung pressures, volumes and derived variables will be noted and compared statistically as well.",[305,25,122,334,335,336,337,338,339,340],"Postoperative Bronchospasm","Postoperative Pleural Effusion","Postoperative Pneumothorax","Postoperative Pneumonia","Postoperative Aspiration Pneumonitis","Mechanical Power","Driving Pressure",[340,339,342,343,25,122,344],"Atelectasis","Pulmonary Complications","Elastic Power","2026-02-08",{"date":317,"type":35},{"date":348,"type":35},"2025-11-03",{"date":189,"type":20},{"name":351,"class":81},"University General Hospital of Patras",{"id":353,"slug":354,"hasResults":11,"nctId":355,"briefTitle":356,"officialTitle":357,"acronym":358,"eligibilityCriteria":359,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":360,"targetDuration":4,"studyType":53,"phases":362,"briefSummary":363,"conditions":364,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":368,"lastUpdatePostDateStruct":369,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":375,"locationsCount":4},"100619899","the-effect-of-the-5t-teach-back-method-on-respiratory-exercise-and-incentive-spirometer-training-100619899","NCT07350616","The Effect of the 5T Teach-Back Method on Respiratory Exercise and Incentive Spirometer Training","The Effect of the 5T Teach-Back Method in Respiratory Exercise and Incentive Spirometer Training on Knowledge Level, Practical Skills, Respiratory Parameters, and Patient Satisfaction: A Randomized Controlled Study","TEACH-BREATHE","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Scheduled for abdominal surgery under general anesthesia\n* Postoperative use of respiratory exercises and incentive spirometry is recommended\n* Expected postoperative hospital stay of more than 3 days\n* Able to read and write and able to communicate effectively\n* Conscious, cooperative, and oriented\n* Willing to participate voluntarily and able to provide written informed consent\n\nExclusion Criteria:\n\n* Severe neurological or cognitive impairment\n* Unstable vital signs or hemodynamic instability\n* Anticipated or required postoperative intensive care unit admission\n* Severe pain that prevents participation in education or assessments\n* Visual or communication impairments that limit participation in education",{"count":361,"type":20},76,[55],"Breathing problems after surgery are common and can lead to serious complications such as low oxygen levels, lung collapse, or pulmonary embolism. These problems increase patient risk and place an additional burden on the healthcare system. Breathing exercises and incentive spirometer use are important methods to prevent these complications. However, many patients have difficulty understanding and correctly performing these exercises when education is limited to standard verbal instructions. This randomized controlled study aims to evaluate whether the 5T Teach-Back education method improves patients' understanding, practical skills, respiratory outcomes, and satisfaction compared with standard verbal education. The study will be conducted in a university hospital and will include 76 adult patients undergoing abdominal surgery under general anesthesia. Participants will be randomly assigned to either an intervention group or a control group.\n\nPatients in the intervention group will receive preoperative breathing exercise and incentive spirometer training using the 5T Teach-Back method, which encourages patients to explain the information back in their own words and repeat the skills until they are correctly understood. Patients in the control group will receive routine verbal education provided by clinical nurses. Outcomes will be measured before surgery and again within 24-72 hours after surgery. These outcomes include patients' knowledge level, correct performance of breathing exercises and spirometer use, respiratory rate, oxygen saturation, lung function test results, and patient satisfaction with nursing care. The results of this study are expected to show whether the 5T Teach-Back method is more effective than standard education in improving postoperative respiratory care and patient satisfaction. The findings may help standardize patient education practices and support nurses in delivering more effective respiratory training before surgery.",[25,342,365,366,367],"Patient Education","Respiratory Exercises","Incentive Spirometry","2026-01-10",{"date":370,"type":35},"2026-01-20",{"date":372,"type":20},"2026-01-15",{"date":374,"type":20},"2027-01-15",{"name":376,"class":81},"Suleyman Demirel University",{"id":378,"slug":379,"hasResults":11,"nctId":380,"briefTitle":381,"officialTitle":382,"acronym":4,"eligibilityCriteria":383,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":384,"enrollmentInfo":385,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":387,"conditions":388,"keywords":391,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":393,"lastUpdatePostDateStruct":394,"startDateStruct":396,"completionDateStruct":398,"leadSponsor":400,"locationsCount":82},"100600697","the-effect-of-single-lung-ventilation-duration-on-postoperative-pulmonary-complications-in-thoracic-surgery-100600697","NCT07100860","The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery","Does Duration Matter? A Study on Single-Lung Ventilation Time and Pulmonary Complications in Thoracic Procedures","Inclusion Criteria:\n\nAge ≥18 years Undergoing thoracic surgery OLV planned during the procedure\n\nExclusion Criteria:\n\nPediatric patients Patients not requiring OLV Previous thoracic surgery","85 Years",{"count":386,"type":20},134,"This observational study investigates the relationship between the duration of single-lung ventilation (SLV) and the incidence of postoperative pulmonary complications (PPCs) such as pneumonia, pneumothorax, hemothorax, acute lung injury, and acute respiratory distress syndrome (ARDS) in adult patients undergoing thoracic surgery. A total of 134 patients aged 18-85 years, scheduled for thoracic surgery requiring SLV, will be monitored. Data including SLV duration, perioperative parameters, and postoperative pulmonary outcomes will be analyzed.",[25,389,390,305],"One Lung Ventilation","Ards",[182,392],"one lung ventilation","2025-12-10",{"date":395,"type":35},"2025-12-18",{"date":397,"type":35},"2025-01-01",{"date":399,"type":20},"2026-01-01",{"name":401,"class":81},"Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital",{"id":403,"slug":404,"hasResults":11,"nctId":405,"briefTitle":406,"officialTitle":406,"acronym":4,"eligibilityCriteria":407,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":408,"enrollmentInfo":409,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":411,"conditions":412,"keywords":415,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":424,"lastUpdatePostDateStruct":425,"startDateStruct":427,"completionDateStruct":429,"leadSponsor":430,"locationsCount":82},"100534515","postoperative-respiratory-and-activity-monitoring-100534515","NCT06239831","Postoperative Respiratory and Activity Monitoring","Inclusion Criteria:\n\n* Must be 18 or older\n* Must be undergoing abdominal surgery\n* Must be high-risk for PPCs (ARISCAT score equal to or greater than 26)\n\nExclusion Criteria:\n\n* Anyone under 18\n* Anyone not undergoing abdominal surgery\n* Anyone that is not high-risk for PPCs (ARISCAT score less than 26)","90 Years",{"count":410,"type":20},30,"This study plans to learn more about specific breathing and activity recommendations for patients after surgery. Participants will be monitored after abdominal surgery to identify what activities help them breathe better and reduce complications after surgery.",[413,414,25],"Hypoventilation","Hypoxemia",[416,417,418,419,420,421,422,182,423],"hypoventilation","postoperative activity","abdominal surgery","mobilization","predicted minute ventilation (MVPred)","accelerometer","chest monitor","surgical outcomes","2025-04-29",{"date":426,"type":35},"2025-04-30",{"date":428,"type":35},"2022-12-22",{"date":74,"type":20},{"name":431,"class":81},"University of Colorado, Denver",{"id":433,"slug":434,"hasResults":11,"nctId":435,"briefTitle":436,"officialTitle":436,"acronym":4,"eligibilityCriteria":437,"healthyVolunteers":11,"sex":16,"minAge":438,"maxAge":4,"enrollmentInfo":439,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":440,"conditions":441,"keywords":4,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":443,"lastUpdatePostDateStruct":444,"startDateStruct":446,"completionDateStruct":448,"leadSponsor":450,"locationsCount":82},"100555540","gut-microbiota-and-pulmonary-complications-after-non-cardiac-elective-surgery-in-elderly-patients-100555540","NCT06513416","Gut Microbiota and Pulmonary Complications After Non Cardiac Elective Surgery in Elderly Patients","Inclusion Criteria:\n\n1. Age: ≥ 65 years old;\n2. Surgery: Upper abdominal surgery (expected duration ≥ 2 hours);\n3. Anesthesia methods: general anesthesia, tracheal intubation;\n4. ASA classification: I-IV levels;\n5. Postoperative Pulmonary Complications Risk Score (ARISCAT): Medium to High Risk\n6. Patients or their families are able to understand the research protocol and are willing to participate in this study, providing written informed consent\n\nExclusion Criteria:\n\n1. Emergency surgery;\n2. This is the second surgery within the past month;\n3. Preoperative presence of pulmonary infection or other serious pulmonary complications\n4. Patients who have used antibiotics, probiotics, and acid suppressants within one month before surgery","65 Years",{"count":52,"type":20},"This study adopts a combination of retrospective and prospective cohort research methods to explore the composition of preoperative oropharyngeal and gut microbiota in elderly patients undergoing elective upper abdominal surgery, aiming to analyze the correlation between preoperative oropharyngeal and intestinal microbiota composition and metabolite levels and the occurrence of postoperative pulmonary complications (PPCs). The research subjects of the retrospective cohort study were participants (ClinicalTrials.gov No. NCT05679661) included in the prospective RCT on the effects of perioperative immune nutrition intervention and oral hygiene on postoperative complications in elderly patients, which was conducted at Peking Union Medical College Hospital from January 2023 to present. The prospective cohort study plans to continue enrolling elderly patients aged ≥ 65 who underwent elective upper abdominal surgery.\n\nThis study collects preoperative oropharyngeal and fecal samples, as well as preoperative plasma from patients for microbial sequencing and untargeted metabolomics analysis. The main outcome measurement is PPCs, which include pneumonia, atelectasis, and hypoxemia within 7 days after surgery. Inflammatory cells and cytokines in peripheral blood are secondary outcomes.",[442,25],"Gut Microbiota","2025-02-26",{"date":445,"type":35},"2025-02-28",{"date":447,"type":35},"2023-02-01",{"date":449,"type":20},"2025-12-31",{"name":451,"class":81},"Peking Union Medical College Hospital",{"id":453,"slug":454,"hasResults":11,"nctId":455,"briefTitle":456,"officialTitle":457,"acronym":4,"eligibilityCriteria":458,"healthyVolunteers":11,"sex":16,"minAge":459,"maxAge":460,"enrollmentInfo":461,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":463,"conditions":464,"keywords":4,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":466,"lastUpdatePostDateStruct":467,"startDateStruct":469,"completionDateStruct":471,"leadSponsor":472,"locationsCount":82},"100546578","diaphragmatic-inspiratory-amplitude-as-a-prognosticator-for-postoperative-pulmonary-complications-after-cardiac-surgery-100546578","NCT06396767","Diaphragmatic Inspiratory Amplitude as a Prognosticator for Postoperative Pulmonary Complications After Cardiac Surgery","Diaphragmatic Inspiratory Amplitude Measured by Ultrasonography as a Prognosticator for Postoperative Pulmonary Complications After Cardiac Surgery: a Prospective Observational Cohort Study","Inclusion Criteria:\n\n* All patients aged\\>18 years and undergoing elective cardiac surgery.\n\nExclusion Criteria:\n\n1. . Redo Cardiac surgery.\n2. . Pre-existing CNS disease (like Parkinson's disease) or Brain injury or Psychiatric disorder\n3. . Emergency cardiac surgery\n4. . Surgeries done via Thoracotomy approach.\n5. . Pre-surgery ICU stay\u002F on NIV\u002F on mechanical ventilation.\n6. . Pre-surgery Hemodynamic instability requiring vasopressors\u002FIABP institution.\n7. . Age\\\u003C18\n8. . Elevated hemidiaphragm before surgery on chest x ray\n9. . Pre-existing neuromuscular disorders (like myasthenia gravis etc.)\n10. . Patients planned for heart transplantation.\n11. . Patients on mechanical circulatory support preoperatively (intra-aortic balloon pump, extracorporeal membrane oxygenation, or ventricular assist device).\n12. . Inability to give consent.","19 Years","99 Years",{"count":462,"type":20},130,"Cardiac surgery is a critical intervention for a variety of cardiovascular conditions, yet it can frequently results in a spectrum of postoperative complications. Amongst various morbidities, Post-Operative Pulmonary Complications (POPCs) represent a significant clinical challenge leading to adverse outcomes like increased morbidity, mortality, and raised healthcare expenditures. The diaphragm, as the principal respiratory muscle, plays a pivotal role in maintaining pulmonary function. Diaphragmatic dysfunction (DD) in the perioperative period of Cardiac surgery has an incidence of up to 20%. Understanding the impact of DD on postoperative pulmonary function is imperative for optimizing patient care and clinical outcomes. Its occurrence has been linked to a spectrum of respiratory complications, ranging from pneumonia to difficulty in weaning from mechanical ventilation. In recent years, the advent of point-of-care ultrasonogram (POCUS) has emerged as a promising modality for real-time monitoring of DD. It offers a more accessible and feasible approach compared to traditional methods, providing immediate feedback on diaphragmatic movement, and facilitates timely intervention. Ultrasound has been used to assess Diaphragmatic Inspiratory Amplitude (DIA) (the expansion of the diaphragm when breathing). DIA has been shown to decrease in the post-operative period after cardiac surgery, which has been well-correlated with the occurrence of POPCs, however, its predictive value has not yet been studied in a cohort of cardiac surgical patients. Hence, we aim to address this gap by exploring the utility of DIA measured by ultrasonogram as a predictive tool in anticipating the occurrence of POPCs. We hypothesize that DIA can predict the occurrence of POPC in cardiac surgical patients. We will recruit 130 patients at University Hospital, London Health Science Centre, to this prospective, observational study.",[25,465],"Cardiac Surgery","2024-10-07",{"date":468,"type":35},"2024-10-09",{"date":470,"type":35},"2024-06-01",{"date":34,"type":20},{"name":473,"class":81},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's"]