[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postoperative-sore-throat-cough-hoarseness\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postoperative-sore-throat-cough-hoarseness":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,52,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100645133","effect-of-endotracheal-tube-cuff-pressure-management-on-postoperative-sore-throat-in-pediatric-laparoscopic-appendectomy-100645133",false,"NCT07678086","Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy","The Effect of Intraoperative Endotracheal Tube Cuff Pressure on Postoperative Sore Throat in Pediatric Patients Undergoing Laparoscopic Appendectomy: A Prospective Randomized Controlled Trial.","Inclusion Criteria:\n\n* Pediatric patients aged 6-18 years\n* Patients with ASA physical status classification I-III\n* Patients scheduled for laparoscopic appendectomy\n* Voluntary written informed consent from the patient's legal guardian\u002Fparent after being informed in detail about the purpose and method of the study..\n\nExclusion Criteria:\n\n* Patients under 6 years of age\n* Patients with ASA IV or higher\n* Patients with preoperative sore throat\n* Patients who have not completed the preoperative fasting period\n* Patients who received intraoperative nasogastric tube\n* Patients who received intraoperative N₂O\n* Patients with complicated appendicitis diagnosis\n* Patients who underwent two or more intubation attempts\n* Patients with surgery duration longer than 2 hours\n* Patients with predicted or likely airway difficulties\n* Patients who underwent conversion from intraoperative laparoscopy to laparotomy\n* Presence of tracheal pathology\n* Congenital anomalies affecting the airway\n* Presence of known upper\u002Flower respiratory tract disease\n* Patients requiring planned postoperative mechanical ventilation\n* Patients in shock\n* Patients with decompensated heart failure or respiratory failure\n* Patient or legal representative's refusal to participate in the study\n* Patients with a history of smoking","ALL","6 Years","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","Abstract Objective:\n\nThe aim of this study is to compare two different ways of adjusting the air-filled cushion (cuff) of the breathing tube used during general anesthesia in children undergoing laparoscopic appendectomy (closed surgery for appendicitis). The goal is to see if maintaining the pressure in this cushion within a safe, specific range (15-18 mmHg) helps prevent or reduce sore throat, hoarseness, and discomfort, which are common postoperative complications in children.\n\nStudy Design:\n\nThis is a prospective, randomized, controlled study. Sixty children aged 6 to 18 years scheduled for laparoscopic appendectomy will be included. Participants will be randomly assigned to two equal groups: Group A (Control Group): Breathing tube cuff pressure is adjusted using the standard \"feeling\" (finger palpation) method common in routine practice. Group B (Intervention Group): Breathing tube cuff pressure is measured throughout the surgery using a medical pressure sensor (manometer) and maintained within a safe range (15-18 mmHg). Research Questions: Does actively monitoring airway pressure reduce the number of children experiencing postoperative sore throat? Does this method reduce the severity of sore throat, cough, hoarseness, or other respiratory discomfort compared to the standard method? What will happen?\n\nDuring surgery, respiratory and heart rate measurements will be recorded every 15 minutes for all participants. After surgery, researchers will visit participants (and their parents) at 2, 6, and 24 hours postoperatively to assess the presence of sore throat, discomfort, or hoarseness. No additional medications or invasive procedures will be used for this study; only how we manage airway pressure will be compared.",[27,28,29,30],"Appendicitis Acute","Postoperative Sore Throat, Cough, Hoarseness","Airway Complications","Respiratory Complications",[32,33,34,35,36,37,38],"Endotracheal tube cuff pressure","Post-anesthetic complications","Pressure transducer","Laparoscopic appendectomy","Pediatric anesthesia","Airway management","postoperative sore throat","NOT_YET_RECRUITING","2026-06-28",{"date":42,"type":43},"2026-07-01","ACTUAL",{"date":45,"type":21},"2026-06-30",{"date":47,"type":21},"2026-08-25",{"name":49,"class":50},"Ankara Etlik City Hospital","OTHER_GOV",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":51},"100602525","phase-4-sore-throat-after-open-neck-elective-surgery-100602525","NCT07124650","Sore Throat After Open Neck Elective Surgery","Effect of Hydrocortisone and Lidocaine on Endotracheal Tube for Sore Throat and Hoarseness After Thyroid\u002FParathyroid Surgery With Neuromonitoring: A Randomized Controlled Trial","STONES","Inclusion Criteria:\n\n* Patients scheduled for elective open surgery on the thyroid\u002Fparathyroid glands with intraoperative neuromonitoring.\n* Age ≥18 years.\n* Willing and able to provide voluntary informed consent for participation in the study.\n\nExclusion Criteria:\n\n* Pregnancy (for women of childbearing potential).\n* Known allergy to hydrocortisone or lidocaine.\n* Refusal to participate in the study.",{"count":61,"type":21},764,[63],"PHASE4","This randomized clinical trial aims to evaluate the effectiveness of two medications-hydrocortisone ointment and lidocaine solution-applied to the endotracheal tube in reducing postoperative throat pain, hoarseness, and cough following thyroid or parathyroid surgery with neuromonitoring.\n\nA total of 764 adult patients undergoing elective neck surgery at Saint-Petersburg State University Hospital will be enrolled and randomly assigned to receive either a hydrocortisone-coated or lidocaine-coated endotracheal tube.\n\nOutcomes will be assessed upon awakening from anesthesia, at 24 hours, and again at 3 days postoperatively.\n\nThe findings may contribute to improving postoperative comfort and recovery for patients undergoing similar surgical procedures.",[28,66],"Thyroid and Parathyroid Surgery",[68,69,70,71,72],"Hydrocortisone","Lidocaine","Endotracheal tube","Neuromonitoring","Randomized controlled trial","RECRUITING","2026-04-06",{"date":76,"type":43},"2026-04-13",{"date":78,"type":43},"2025-09-15",{"date":80,"type":21},"2027-05",{"name":82,"class":83},"Saint Petersburg State University, Russia","OTHER",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":16,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":22,"phases":95,"briefSummary":96,"conditions":97,"keywords":101,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":4},"100596067","hyaluronic-acid-for-prevention-of-post-intubation-sore-throat-and-hoarseness-100596067","NCT07040631","Hyaluronic Acid for Prevention of Post-Intubation Sore Throat and Hoarseness","Effect of Hyaluronic Acid on Post-Intubation Sore Throat and Hoarseness in Breast Cancer Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 19 to 80 years\n* Scheduled to undergo breast cancer surgery under general anesthesia with endotracheal intubation\n* American Society of Anesthesiologists (ASA) physical status I to III\n\nExclusion Criteria:\n\n* Mallampati classification of III or higher\n* Recent upper respiratory infection or symptoms of upper airway infection\n* Pre-existing laryngeal disease or chronic respiratory conditions (e.g., asthma, chronic bronchitis)\n* Current use of systemic steroids\n* Refusal to provide informed consent\n* Determined to be unsuitable for study participation by the investigator","19 Years","80 Years",{"count":94,"type":21},92,[24],"The goal of this clinical trial is to find out whether applying Endotra Gel, a hyaluronic acid-based gel, to the endotracheal tube can help reduce sore throat and hoarseness after surgery.\n\nThese symptoms are common after general anesthesia when a endotracheal tube is placed into the trachea. They can cause discomfort and affect patient recovery.\n\nThe main questions this study aims to answer are:\n\n* Does Endotra Gel reduce the chance of having a sore throat after surgery?\n* Does it help improve hoarseness or coughing after surgery?\n\nParticipants in this study will:\n\n* Undergo general anesthesia for breast cancer surgery\n* Be randomly assigned to one of two groups:\n\n  * One group will receive Endotra Gel applied to the endotracheal tube before intubation\n  * The other group will have standard care with no gel\n* Be monitored for sore throat, hoarseness, and coughing right after surgery and on the day after surgery\n* Answer questions about their symptoms and satisfaction with their recovery The results will help researchers learn whether using Endotra Gel during intubation can improve patient comfort and reduce airway irritation after surgery.",[98,28,99,100],"Breast Cancer","Endotracheal Intubation","General Anesthesia",[102,103,104,99,105,106,107],"Postoperative Sore Throat","Hyaluronic Acid","Lubricating Gel","hoarseness","breast cancer surgery","randomized controlled trial","2025-06-24",{"date":110,"type":43},"2025-06-27",{"date":112,"type":21},"2025-06",{"date":114,"type":21},"2026-02",{"name":116,"class":83},"Pusan National University Yangsan Hospital"]