[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postoperative-vomiting\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postoperative-vomiting":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,73,107],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100604648","advancing-strategies-to-optimize-the-perioperative-management-of-postoperative-nausea-and-vomiting-aspire-ponv-trial-100604648",false,"NCT07152249","Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial","ASPIRE-PONV","Adult Inclusion Criteria\n\n* Age ≥ 18 years\n* Planned surgery with general anesthesia with endotracheal intubation or laryngeal mask airway\n* Meet zero or more risk factors for PONV ( history of motion sickness or postoperative nausea and vomiting, non-smoker, female sex, duration of inhalation anesthesia greater than 1 hour, undergoing high risk surgical procedure (cholecystectomy, laparoscopy, gynecologic), and perioperative opioid use)\n\nAdult Exclusion Criteria\n\n* ASA 6 including organ procurement,\n* Patients anticipated to be transferred directly to the intensive care unit intubated,\n* Procedure types:\n\n  * Electroconvulsive therapy,\n  * Intubation only cases,\n  * labor epidurals,\n  * transesophageal echocardiography (TEE)\u002Fcardioversion,\n  * surgery duration \\\u003C 30 minutes.\n\nOperating Room Anaesthesia Provider Inclusion Criteria\n\nAny operating room anaesthesia provider of eligible patients will be included.","ALL","18 Years",{"count":19,"type":20},19480,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this prospective, unblinded, pragmatic and repeated crossover trial is to learn if clinical decision support alerts will impact postoperative nausea and vomiting (PONV) prophylaxis and reduce PONV rates in adult patients who have planned surgery with general anesthesia. The main aim is to improve PONV, establishing a scalable Clinical Decision Support (CDS) Tool for personalized PONV prevention.\n\nThe primary hypothesis is that, compared with standard care, the Anesthesia Workflow-Driven Clinical Decision Support Tool for Personalized PONV Prevention will be associated with a significant improvement in the rate of appropriate administration of PONV prophylaxis and a significant decrease in the incidence of PONV.\n\nThis study will evaluate a new clinical decision support (CDS) tool designed to improve how and when PONV prevention strategies are used. Unlike traditional tools that provide generic, one-time alerts, this new system is integrated into the electronic health record (EHR) and delivers timely, targeted reminders to anesthesia providers at key moments during a patient's surgical care-such as before surgery begins, after anesthesia is given, and before the patient wakes up. These alerts are based on each patient's individual risk for PONV and are intended to support, not replace, clinical judgment. The study will use a crossover design over 12 months, alternating between periods when the tool is active and when it is not. The goal is to determine whether this time-sensitive, workflow-integrated tool can lead to better adherence to best practices and improved patient outcomes.",[26,27],"Postoperative Nausea","Postoperative Vomiting",[29],"clinical decision support","RECRUITING","2026-01-09",{"date":33,"type":34},"2026-01-12","ACTUAL",{"date":36,"type":34},"2025-09-03",{"date":38,"type":20},"2026-09",{"name":40,"class":41},"Vanderbilt University Medical Center","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":42},"100605477","comparison-of-two-plane-blocks-used-in-open-ventral-hernia-repair-operations-100605477","NCT07163026","Comparison of Two Plane Blocks Used in Open Ventral Hernia Repair Operations","Comparison of Analgesic Efficacy of Erector Spinae Plane Block and External Oblique-Intercostal Plane Block in Patients Undergoing Open Ventral Hernia Repair","Inclusion Criteria:\n\n* Patients scheduled for open ventral hernia repair under general anesthesia\n* Patients with ASA scores (American Society of Anesthesiologists) 1 and 2\n* Patients with a body mass index between 18.5 and 34.9\n\nExclusion Criteria:\n\n* Patients scheduled for open ventral hernia repair under spinal or epidural anesthesia\n* Patients who have previously undergone spine surgery.\n* Patients with known local anesthetic allergy\n* Pregnant women\n* Mentally uncooperative patients\n* Patients with a history of chronic analgesic use","65 Years",{"count":52,"type":20},50,[23],"The aim of this study is to compare the postoperative analgesic efficacy of bilateral erector spinae plane block and bilateral external oblique-intercostal plane block in patients undergoing open ventral hernia repair.",[56,57,26,27],"Ventral Hernia","Postoperative Pain",[59,60,61],"erector spinae plane block","external oblique intercostal plane block","bupivacain","NOT_YET_RECRUITING","2025-09-14",{"date":65,"type":34},"2025-09-16",{"date":67,"type":20},"2025-09-30",{"date":69,"type":20},"2025-12-15",{"name":71,"class":72},"Ankara Ataturk Sanatorium Training and Research Hospital","OTHER_GOV",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":21,"phases":83,"briefSummary":85,"conditions":86,"keywords":90,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":106},"100573993","phase-4-intraoperative-autonomic-blockade-for-laparoscopic-cholecystectomy-100573993","NCT06753500","Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy","Intraoperative Autonomic Blockade to Prevent Early Postoperative Pain After Laparoscopic Cholecystectomy: A Double-Blind, Randomized Controlled Trial","ANB","Inclusion Criteria:\n\n* Elective or emergency laparoscopic cholecystectomy for cholelithiasis with or without cholecystitis.\n\nExclusion Criteria:\n\n* Associated biliary pathologies (e.g., biliary pancreatitis, cholangitis).\n\n  * Additional procedures, such as formal bile duct exploration. Conversion to an open approach\n  * Anesthesia or Surgical complications that require intensive care unit\n* Allergies to local anesthetics",{"count":82,"type":20},60,[84],"PHASE4","This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid). This technique aims to block the hepatic branches of the celiac plexus to improve visceral pain control and its associated clinical manifestations, reduce analgesic requirements, and lower readmission rates, thereby facilitating recovery.",[87,88,89,26,27],"Visceral Pain","Analgesia","Opioid Use",[91,92,93,94,95,96],"autonomic neural blockade,","Visceral pain","postoperative nausea","Postoperative vomiting","analgesic consumption","opioid use","2025-01-25",{"date":99,"type":34},"2025-01-28",{"date":101,"type":34},"2025-01-15",{"date":103,"type":20},"2025-11-04",{"name":105,"class":41},"Universidad Simón Bolívar",2,{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":113,"sex":16,"minAge":114,"maxAge":4,"enrollmentInfo":115,"targetDuration":4,"studyType":21,"phases":117,"briefSummary":118,"conditions":119,"keywords":120,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":42},"100548576","the-impact-of-nasogastric-tube-gastric-decompression-on-postoperative-nausea-and-vomiting-in-orthognathic-surgery-100548576","NCT06422793","The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery","Inclusion Criteria:\n\n* Patients over the age of 16 at the time of consent undergoing orthognathic surgery for the correction of dentofacial deformities at the Victoria General Hospital during the study period.\n\nOrthognathic surgery to include:\n\n1. Patients who receive single-jaw surgery (i.e. BSSO \\[Bilateral Sagittal Split Osteotomy\\] only, or LeFort only).\n2. Patients receiving double-jaw surgery (i.e. BSSO and LeFort).\n3. Patients undergoing a functional genioplasty in addition to another osteotomy (i.e. BSSO and\u002For LeFort).\n\nExclusion Criteria:\n\n* Patients will be excluded if they do not meet inclusion criteria or if they have risk factors known to directly impact PONV and\u002For cause delayed gastric emptying:\n\n  1. Patients under the age of 16 at the time of consent.\n  2. Patients contraindicated to undergo elective surgery, including pregnant patients.\n  3. Patients undergoing a functional genioplasty procedure only.\n  4. Patients taking GLP-1 receptor agonists).\n  5. Patients with known gastroparesis.",true,"16 Years",{"count":116,"type":20},92,[23],"This study will compare the incidence of postoperative nausea and vomiting during the first 24 hours following corrective jaw surgery (orthognathic surgery) in patients with and without nasogastric tube gastric decompression.",[26,27],[121,122,123],"nasogastric tube","orthognathic surgery","gastric decompression","2025-01-12",{"date":126,"type":34},"2025-01-14",{"date":128,"type":34},"2024-12-04",{"date":130,"type":20},"2025-12",{"name":132,"class":41},"Nova Scotia Health Authority"]