[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postpartum-complication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postpartum-complication":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,49,78,110,144,176,206,237,272,298,322],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100641188","effects-of-scapular-posterior-tilt-exercises-and-cross-body-stretching-in-postpartum-women-with-rounded-shoulders-100641188",false,"NCT07576296","Effects of Scapular Posterior Tilt Exercises and Cross-Body Stretching in Postpartum Women With Rounded Shoulders","Comparative Effects of Scapular Posterior Tilt Exercises and Cross-Body Stretching on Breastfeeding Efficiency Latch Quality and Posture in Postpartum Women With Rounded Shoulders","Inclusion Criteria:\n\n* Mutiparous females.\n* previous cesarean section deliveries\n* Postpartum women between 2 weeks and 6 months postpartum.\n* Experiencing shoulder discomfort or poor posture\n\nExclusion Criteria:\n\n* History of recent trauma or surgery such a Arthroscopy for Impingement Syndrome, Shoulder Replacement that affecting the shoulder complex.\n* Mother with history of breast cancer and hepatitis\n* History of shoulder surgery, trauma, or musculoskeletal disorders affecting the upper back\u002Fshoulder (Trapezius muscles train, Levator scapulae and rhomboid overuse)\n* Severe postnatal complications (e.g., mastitis, postpartum depression, uncontrolled hypertension or diabetes.",true,"FEMALE","20 Years","35 Years",{"count":21,"type":22},34,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to compare the effects of scapular posterior tilt exercises and cross-body stretching on breastfeeding efficiency, latch quality, and posture in postpartum women with rounded shoulders.",[28],"Postpartum Complication",[30,31,32,33,34,35],"Female","Shoulder","Breastfeeding","Scapula","Posture","Postpartum period","RECRUITING","2026-05-04",{"date":39,"type":40},"2026-05-08","ACTUAL",{"date":42,"type":40},"2025-10-01",{"date":44,"type":22},"2026-07-01",{"name":46,"class":47},"Riphah International University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":16,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100636970","community-health-worker-assessment-for-postpartum-health-100636970","NCT07572604","Community Health Worker Assessment for Postpartum Health","Community Health Worker Assessment for Postpartum Health (CAREPATH)","CAREPATH","Inclusion Criteria:\n\n* Age 16-44 years old\n* ≤ 38 weeks pregnant\n* Ability to speak English, Spanish or Marshallese\n\nExclusion Criteria:\n\n* Type 1 diabetes on an insulin pump followed closely by endocrinology\n* Uncontrolled Type 2 diabetes\n* End stage renal disease followed closely by nephrology\n* ICU admission at any point during pregnancy or delivery hospitalization\n* Other maternal conditions requiring additional surgeries (i.e. cesarean hysterectomy or intrapartum or postpartum oophorectomy\u002Fappendectomy)\n* Incarceration\n* Mental disability limiting decision-making capacity\n* Uncontrolled chronic hypertension\n* HELLP syndrome during pregnancy\n* Sickle cell disease\n* Maternal heart condition or heart disease\n* Opioid use disorder\n* Lupus\n* Thrombophilia or blood clots\n* Other maternal conditions or complications, known during pregnancy or delivery hospitalization, requiring prolonged hospitalization postpartum","16 Years","44 Years",{"count":60,"type":22},500,[25],"The goal of this randomized controlled trial is to compare the CAREPATH intervention with standard of care on postpartum outcomes among up to 500 postpartum individuals. The CAREPATH includes 3 postpartum telehealth visits from a perinatal CHW.\n\nThe study will address the following aims:\n\nAim 1: Compare: A) CARE PATH and B) standard of care among postpartum individuals on:\n\nAim 1.A: postpartum visit completion.\n\n* Hypothesis 1.A: Patients assigned to the CARE PATH will have higher completion of their postpartum visit compared to those receiving standard of care.\n\nAim 1.B: early detection of postpartum complications.\n\n* Hypothesis 1.B: Patients assigned to the CARE PATH will be more likely to experience early detection of postpartum complications that arise compared to those receiving standard of care.\n\nAim 1.C: hospital readmission and ED visits postpartum.\n\n* Hypothesis 1.C: Patients assigned to the CARE PATH will be less likely to have hospital readmission or an ED visit compared to those receiving standard of care.\n\nAim 2: Explore the impact of A) CARE PATH and B) standard of care on reproductive life planning\u002Fcontraceptive counseling.\n\n* Hypothesis 2: Patients assigned to the CARE PATH will be more likely to report reproductive life planning\u002Fcontraceptive counseling.",[28,64],"Health Care Seeking Behavior",[66,67,68],"Postpartum visit","Postpartum care","Postpartum complications","NOT_YET_RECRUITING","2026-05-01",{"date":72,"type":40},"2026-05-07",{"date":44,"type":22},{"date":75,"type":22},"2029-08-31",{"name":77,"class":47},"University of Arkansas",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":23,"phases":89,"briefSummary":91,"conditions":92,"keywords":97,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":109},"100553123","phase-4-swift---swiss-factor-xiii-trial-in-pph-100553123","NCT06481995","SWIFT - SWIss Factor XIII Trial in PPH","Early Factor XIII Replacement in Postpartum Hemorrhage: Multi-center, Randomized, Controlled, Investigator-initiated Trial","SWIFT","Inclusion Criteria:\n\n* planned vaginal delivery\n* singleton vital pregnancy\n* gestational age at delivery \\>= 30+0 weeks\n* maternal weight at admission for delivery \\\u003C100 kg\n\nExclusion Criteria:\n\n* Antithrombotic therapy in pregnancy (therapeutic dosage) until admission for delivery (LMWH, UFH)\n* diagnosis of preeclampsia (ISSHP classification , eclampsia or HELLP syndrome),\n* known history of deep vein thrombosis or pulmonary embolism,\n* known diagnosis of bleeding disorder or thrombophilia,\n* known thrombocytopenia during second half of pregnancy with thrombocytes \\\u003C 100 G\u002FL,\n* known anemia during second half of pregnancy with Hb\\\u003C80 g\u002FL,\n* known sickle cell disease,\n* known malignant tumor(s),\n* participation in another study with investigational drug within the 30 days preceding and during the present study,\n* inability to follow the procedures of the study, e.g. due to language problems,\n* known or suspected non-compliance, drug or alcohol abuse.\n\nExclusion criteria prior randomization\n\n* Maternal fever ≥39.0°C\n* unplanned cesarean delivery is performed,\n* Measured Blood Loss remains \\\u003C 700 mL after administration of 1g tranexamic acid .\n* Postpartum hemorrhage due to occult bleeding (intra-abdominal, retroperitoneal, parametric),","18 Years",{"count":88,"type":22},988,[90],"PHASE4","The goal of this trial is to determine if postpartum blood loss can be reduced by replenishing coagulation factor XIII (FXIII) at an early stage of postpartum hemorrhage (PPH).\n\nSummary of current body of evidence:\n\n* Morbidity and mortality due to PPH is rising.\n* Current guidelines focus on replenishment of fibrinogen as an initial step in the treatment of PPH-related coagulopathy, despite non-conclusive evidence in all prospective trials.\n* Trials from other specialties demonstrate a significant impact of FXIII on perioperative bleeding complications; a previous study at the University Hospital Zurich showed that pre-partum factor XIII activity had a strong association to postpartum blood loss.\n\nTherefore, this nationwide, multi-center, randomized, controlled trial in multiple perinatal centers across Switzerland will be conducted. The goal is to determine if postpartum blood loss and PPH-related complications can be reduced by replenishing FXIII.\n\nAll participating women receive, according to the national guideline, 1g tranexamic acid (TXA) i.v. in case of PPH (measured blood loss \\[MBL\\] ≥ 500 mL) during the pre-study phase. Randomization takes place if bleeding continues and exceeds 700mL. The intervention group then receives FXIII (Fibrogammin®) according to approved dosage in addition to obstetric standard of care treatment for causes of PPH; the control group receives only standard of care treatment.",[93,94,95,96,28],"Postpartum Hemorrhage","Coagulation Disorder","Coagulation Factor Deficiency","Hemorrhage",[98,99],"Postpartum hemorrhage","coagulation factor XIII","2026-04-21",{"date":102,"type":40},"2026-04-27",{"date":104,"type":40},"2024-07-09",{"date":106,"type":22},"2028-12-31",{"name":108,"class":47},"Christian Haslinger",9,{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":23,"phases":120,"briefSummary":121,"conditions":122,"keywords":128,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":48},"100594452","u-cavit-versus-standard-of-care-for-prevention-of-atonic-postpartum-hemorrhage-after-cesarean-section-in-high-risk-women-100594452","NCT07019623","U-CaVIT Versus Standard of Care for Prevention of Atonic Postpartum Hemorrhage After Cesarean Section in High-risk Women.","Uro-catheter Vacuum-induced Uterine Tamponade (U-CaVIT) Versus Standard of Care for Prevention of Atonic Postpartum Hemorrhage After Cesarean Section in High-risk Women: a Monocentric Randomized-controlled Pilot Study.","UCaVIT Pilot","Inclusion Criteria:\n\n* Signed informed consent\n* Maternal age ≥18 years\n* Gestational age ≥30+0 weeks of pregnancy at day of delivery\n* Vital pregnancy\n* Delivery mode: planned cesarean delivery\n* High-risk patient for PPH specified by the presence of at least one of the following characteristics: Previous PPH, obesity (BMI ≥30 kg\u002Fm2), high parity (patient who has had ≥4 previous births (live or stillborn) at ≥20 weeks of gestation), very advanced maternal age ≥45 years, multiple gestation, polyhydramnios (defined as amniotic fluid index \\> 25 cm or deepest amniotic fluid pocket \\> 8 cm) at admission to delivery, suspected fetal macrosomia (estimated fetal weight ≥ 4500g)\n\nExclusion Criteria:\n\n* Insufficient language skills in German or English to understand and sign informed consent\n* Participation in another interventional study\n* Emergency cesarean section (incl. patients undergoing cesarean after failed vaginal delivery)\n* Subjects who change their delivery plan from vaginal to cesarean section in the course of hospitalization\n* Women with regular and painful contractions and women who do not have time for sufficient consideration\n* Clinical situations in which vacuum-induced uterine tamponade is unlikely to be effective or is contraindicated:\n\n  * Uterine or vaginal anomalies (genital tract congenital anomalies)\n  * Cesarean section due to placenta previa or suspected placenta accreta spectrum\n  * Suspected uterine rupture\n  * Injuries of the cervix or vagina\n  * Submucous or intramural uterine fibroids which are buldging into the uterine cavity\n  * Deep endometriosis \\[16, 17\\]\n* Planned atony-prophylaxis with oxytocin due to contraindication for carbetocin\n* Previous MMC-repair (myelomeningocele-repair)\n* Clinical diagnosis of chorioamnionitis, sepsis\n* Known allergy to silicone\n* Known and proven diagnosis of bleeding disorder or thrombophilia\n* Known thrombocytopenia during second half of pregnancy with thrombocytes \\\u003C 100 G\u002FL\n* Known anemia during second half of pregnancy with Hb\\\u003C80",{"count":119,"type":22},70,[25],"This pilot study aims to assess performance, safety and feasibility of U-CaVIT method (Uro-Catheter Vacuum Induced Tamponade), using the Rüsch® Brillant Silicone Balloon Catheter, an urological catheter, for the prevention of atonic PPH in high-risk women undergoing cesarean delivery.\n\nThe U-CaVIT method has been implemented at the Department of Obstetrics at university hospital of Zurich (USZ) due to temporary supply issues with the Bakri® Balloon Catheter. The Rüsch® Balloon Catheter is used in case of uterine atony when standard first-line uterotonic treatments have failed or in some cases as add-on therapy in non-atonic PPH. In the meantime, the use of U-CaVIT has become standard practice at the USZ for the treatment of atonic PPH, appearing to be user-friendly, clinically effective according to treating physicians, well tolerated by the treated women and cost-saving compared to the previously used Bakri® Balloon.",[123,96,28,124,125,126,127],"Postpartum Hemorrhage (Primary)","Delivery ,Complications,Maternal","Pregnancy Complications","Cesarean Delivery","Balloon",[93,129,130,131,132,133,134,135],"Delivery complications","high risk patients","Pregnancy","Balloon Catheter","Tamponade","prophylactic","Vacuum-induced tamponade","2026-04-17",{"date":138,"type":40},"2026-04-22",{"date":140,"type":40},"2025-05-28",{"date":142,"type":22},"2026-11",{"name":108,"class":47},{"id":145,"slug":146,"hasResults":11,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":4,"eligibilityCriteria":150,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":151,"enrollmentInfo":152,"targetDuration":4,"studyType":23,"phases":154,"briefSummary":155,"conditions":156,"keywords":158,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":175},"100633007","combined-effects-of-stability-oriented-breathing-exercises-and-kegels-exercises-in-postpartum-women-100633007","NCT07521085","Combined Effects Of Stability Oriented Breathing Exercises and Kegel's Exercises in Postpartum Women","Combined Effects Of Stability Oriented Breathing Exercises and Kegel's Exercises On Inter-recti Distance, Lumbopelvic Pain and Strength In Postpartum Women","Inclusion Criteria:\n\n* • Age between 18-40 years\n\n  * Postpartum duration of 42-49 days\n  * Inter-recti distance (IRD) between 3-5 cm\n  * Numeric pain scale score ≤ 6 for pain\n  * No prior physiotherapy or exercise guidance received\n\nExclusion Criteria:\n\n* • Pain during the training period\n\n  * Patients with any heart or respiratory disease including excessive coughing and sneezing\n  * Patients with any kind of pelvic or abdominal surgery\n  * Significant organ dysfunction or psychiatric illness\n  * Diagnosis of malignant tumors","40 Years",{"count":153,"type":22},60,[25],"The postpartum period often presents challenges such as increased inter-recti distance (diastasis recti), lumbopelvic pain, and reduced core strength. This study is designed as a randomized controlled trial to evaluate the combined effects of stability-oriented breathing exercises and Kegel exercises on inter-recti distance (IRD), lumbopelvic pain, and muscle strength in postpartum women. A total sample size of 66 participants per group was determined with a 10% dropout rate accounted for.\n\nThe study will use a non-probability convenience sampling technique. It will be conducted at the University of Lahore Teaching Hospital and Sehat Medical complex. Inclusion criteria include women aged 18-40 years, with a history of cesarean sections, an IRD between 3-5 cm. Outcome measures include IRD , pelvic floor muscle strength, lumbopelvic pain (measured using a 10 cm numeric pain scale). Participants will be randomly assigned to either Group A (Kegel-only) or Group B (Kegel + breathing exercises). Both groups will train three times weekly for eight weeks. All data analysis will be performed using SPSS version 27.",[28,157],"Strength",[159,160,161,162,163,164,165,166],"Breathing exercises","Core strength","Diastasis recti abdominis","Inter recti distance","Kegel exercises","Lumbopelvic pain","Postpartum women","Stability training","2026-04-02",{"date":169,"type":40},"2026-04-09",{"date":171,"type":40},"2025-08-31",{"date":173,"type":22},"2026-09",{"name":46,"class":47},2,{"id":177,"slug":178,"hasResults":11,"nctId":179,"briefTitle":180,"officialTitle":180,"acronym":181,"eligibilityCriteria":182,"healthyVolunteers":16,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":183,"targetDuration":4,"studyType":23,"phases":185,"briefSummary":186,"conditions":187,"keywords":188,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":197,"lastUpdatePostDateStruct":198,"startDateStruct":200,"completionDateStruct":202,"leadSponsor":204,"locationsCount":175},"100532864","impact-improving-maternal-postpartum-access-to-care-through-telemedicine-100532864","NCT06218355","IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine","IMPACT","Inclusion Criteria:\n\n* Postpartum women who deliver a live born infant at Parkland Hospital or Grady Health and receive postpartum care at dedicated community clinics.\n* Due to the nature of the study, all will be women, and all will be postpartum, thus of reproductive age. Postpartum women 18 years of age and older will be considered for inclusion if informed consent can be obtained.\n\nExclusion Criteria:\n\n* Postpartum women who do not deliver at Parkland Hospital or Grady Health will not receive postpartum care in the pre-specified community clinics for Parkland health systems.\n* Patients with a primary language other than English or Spanish.",{"count":184,"type":22},3500,[25],"The purpose of this study is to compare two complex, multi-component evidence-based postpartum interventions in underserved populations of lower socioeconomic status in an effort to reduce maternal morbidity and mortality.",[28],[189,190,191,192,193,194,195,196],"telemedicine","hypertension","wound infection","readmission","metritis","mastitis","maternal mortality","postpartum complications","2026-03-14",{"date":199,"type":40},"2026-03-17",{"date":201,"type":40},"2024-03-01",{"date":203,"type":22},"2028-09-01",{"name":205,"class":47},"University of Texas Southwestern Medical Center",{"id":207,"slug":208,"hasResults":11,"nctId":209,"briefTitle":210,"officialTitle":211,"acronym":212,"eligibilityCriteria":213,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":214,"enrollmentInfo":215,"targetDuration":4,"studyType":23,"phases":217,"briefSummary":218,"conditions":219,"keywords":220,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":228,"lastUpdatePostDateStruct":229,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":235,"locationsCount":48},"100537100","healing-equity-advocacy-and-respect-for-mamas-100537100","NCT06273436","Healing, Equity, Advocacy and Respect for Mamas","Comparing Standard of Care Versus a Technology-Based Approach To Reduce Postpartum Emergency Department Visits","HEAR4Mamas","Inclusion Criteria for Postpartum Women\n\n* Postpartum woman within approximately 2 weeks of delivering a baby of gestational age ≥ 26 weeks in South Carolina.\n* Aged 16-49 years old.\n* Insured by Medicaid.\n\nExclusion Criteria for Postpartum Women\n\n* Plans to relocate outside of SC anytime during the postpartum year.\n* Plans to discontinue Medicaid health insurance during the postpartum year.\n* Speaks a language other than English or Spanish.\n* Incarcerated\u002Fpending incarceration during peripartum period.\n* Currently institutionalized.\n* Enrolled in current MUSC study funded by PCORI (#Pro00123833)\n* Does not have and\u002For does not wish to use their personal cell phone for the study.\n\nInclusion Criteria for Obstetric Providers and Hospital Administrators\n\n\\- OB provider working at a delivery hospital in SC and directly involved in the care of postpartum women; or hospital administrator working in a delivery hospital in SC and job responsibilities relate to the postpartum unit.\n\nExclusion Criteria for Obstetric Providers and Hospital Administrators\n\n* Less than 1 month of HEAR 4 Mamas experience if involved in the hospital where participants are recruited from.\n* Unable or unwilling to commit to completing surveys or an interview.\n* Speaking a language other than English.","49 Years",{"count":216,"type":22},2894,[25],"The goal of the proposed research is to test the comparative effectiveness of AIM safety bundles for post-partum women delivered in-person vs. via text\u002Fphone to improve early detection of and timely care for complications during the first six weeks postpartum for women experiencing significant health disparities.",[28],[221,222,223,224,225,226,227],"AIM (Alliance for Innovation on Maternal Health) safety bundles","Randomized Controlled Trial (RCT)","Emergency Department (ED) visits","Shared Decision Making (SDM)","Patient-Reported Outcomes (PROs)","Patient Stakeholder Group (PSG)","Study Advisory Committee (SAC)","2026-02-12",{"date":230,"type":40},"2026-02-17",{"date":232,"type":40},"2024-05-28",{"date":234,"type":22},"2030-03-30",{"name":236,"class":47},"Medical University of South Carolina",{"id":238,"slug":239,"hasResults":11,"nctId":240,"briefTitle":241,"officialTitle":242,"acronym":243,"eligibilityCriteria":244,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":245,"enrollmentInfo":246,"targetDuration":4,"studyType":248,"phases":4,"briefSummary":249,"conditions":250,"keywords":254,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":266,"completionDateStruct":268,"leadSponsor":270,"locationsCount":4},"100624264","patient-reported-outcomes-in-women-with-postpartum-abdominal-wall-insufficiency-ppawis-100624264","NCT07407374","Patient-Reported Outcomes in Women With Postpartum Abdominal Wall Insufficiency (PPAWIS)","A Prospective Observational Cohort Study of Quality of Life, Body Image, and Sexual Function in Women With Postpartum Abdominal Wall Insufficiency Syndrome (PPAWIS) Using Patient-Reported Outcome Measures","EMPOWER","Inclusion Criteria:\n\n* Female, age 18-65 years\n* Postpartum status: at least 6 months after last delivery\n* Clinical diagnosis of postpartum abdominal wall insufficiency syndrome (PPAWIS), defined by abdominal wall dysfunction symptoms and\u002For significant quality-of-life impact, with supportive findings on physical examination and\u002For imaging (e.g., diastasis recti and\u002For related abdominal wall insufficiency features)\n* Receiving routine clinical care for PPAWIS at the study site (surgical)\n* Able and willing to provide informed consent and complete patient-reported outcome questionnaires at baseline and follow-up\n\nExclusion Criteria:\n\n* Current pregnancy\n* Planned pregnancy during the follow-up period (up to 12 months), if expected to interfere with outcome assessment\n* Inability to complete questionnaires due to cognitive impairment or insufficient language proficiency in the validated questionnaire language version\n* Severe uncontrolled psychiatric condition that, in the investigator's opinion, would prevent informed consent or reliable questionnaire completion\n* Participation in another interventional study that could materially affect patient-reported outcomes related to abdominal wall function during the follow-up period","65 Years",{"count":247,"type":22},30,"OBSERVATIONAL","Postpartum abdominal wall insufficiency syndrome (PPAWIS) is a multidimensional condition that may affect physical function, quality of life, body image, and sexual health in women after childbirth. Anatomical findings alone do not fully explain symptom burden or patient experience.\n\nThis prospective observational cohort study will collect validated patient-reported outcome measures (PROMs) from women with PPAWIS receiving routine care. PROMs will be assessed at baseline and during follow-up to describe symptom burden and changes over time. The study aims to improve understanding of the patient-centered impact of PPAWIS and to support development of standardized assessment pathways in clinical practice.",[251,252,28,253],"Diastasis Recti and Weakness of the Linea Alba","Abdominal Wall Defect","Abdominal Wall Anomaly",[255,256,257,258,259,260,261,262,263],"PROMs","postpartum abdominal wall insufficiency","PPAWIS","patient-reported outcomes","sexual function","women's health","core stability","quality of life","abdominal wall reconstruction","2026-02-05",{"date":228,"type":40},{"date":267,"type":22},"2026-02-20",{"date":269,"type":22},"2027-01-01",{"name":271,"class":47},"Swissmed Hospital",{"id":273,"slug":274,"hasResults":11,"nctId":275,"briefTitle":276,"officialTitle":277,"acronym":278,"eligibilityCriteria":279,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":280,"targetDuration":4,"studyType":23,"phases":281,"briefSummary":283,"conditions":284,"keywords":287,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":289,"lastUpdatePostDateStruct":290,"startDateStruct":292,"completionDateStruct":294,"leadSponsor":296,"locationsCount":48},"100481599","phase-3-safest-choice-of-antihypertensive-regimen-for-postpartum-hypertension-100481599","NCT05551104","Safest Choice of Antihypertensive Regimen for Postpartum Hypertension","Safest Choice of Antihypertensive Regimen for Postpartum Hypertension: A Randomized Control Trial (SCARPH)","SCARPH","Inclusion Criteria:\n\n* Female\n* Women who develop postpartum hypertension\\* after delivery of the placenta or chronic hypertensive postpartum women who require medication for blood pressure control.\n\n  * Postpartum hypertension requiring treatment are defined as systolic blood pressure greater than or equal to 140mmHg or diastolic blood pressure greater than or equal to 90mmHg on at least 2 occasions at least 4 hours apart, or systolic blood pressure greater than or equal to 160mmHg or diastolic blood pressure greater than 110mmHg sustained for more than 15 minutes.\n\nExclusion Criteria:\n\n* History of moderate persistent asthma, coronary artery disease, heart failure, AV heart block, pulmonary edema\n* Contraindication to either Nifedipine or Labetalol\n* HR \\\u003C60 or \\>110\n* Native language other than English or Spanish",{"count":60,"type":22},[282],"PHASE3","The purpose of this investigator-initiated randomized control trial is to determine whether oral Nifedipine versus oral Labetalol is superior in controlling high blood pressures in the postpartum period.",[28,285,286],"Maternal Hypertension","High Blood Pressure",[288],"Postpartum Hypertension","2026-02-02",{"date":291,"type":40},"2026-02-04",{"date":293,"type":40},"2023-05-08",{"date":295,"type":22},"2027-12",{"name":297,"class":47},"Loma Linda University",{"id":299,"slug":300,"hasResults":11,"nctId":301,"briefTitle":302,"officialTitle":303,"acronym":4,"eligibilityCriteria":304,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":305,"targetDuration":4,"studyType":23,"phases":307,"briefSummary":308,"conditions":309,"keywords":310,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":313,"startDateStruct":315,"completionDateStruct":317,"leadSponsor":319,"locationsCount":4},"100620104","carbetocin-vs-misoprostol-for-postpartum-hemorrhage-prevention-100620104","NCT07353281","Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention","Carbetocin Versus Misoprostol for the Prevention of Postpartum Hemorrhage After Vaginal Delivery in Women With Risk Factors: A Prospective Randomized Study","Inclusion Criteria\n\n* Women aged 18 years or older\n* Singleton pregnancy\n* Gestational age 37-42 weeks\n* Cephalic presentation\n* Vaginal delivery\n* Presence of one or more risk factors for postpartum hemorrhage, including:\n* Grand multiparity (≥5 previous deliveries)\n* History of postpartum hemorrhage\n* History of manual removal of placenta\n* Estimated fetal weight ≥4,000 grams\n* Polyhydramnios\n* Chorioamnionitis\n* Prolonged oxytocin use during labor (third augmentation cycle or more)\n* Eligible for prophylactic uterotonic therapy after delivery\n* Provided written informed consent\n\nExclusion Criteria\n\n* Multiple gestation\n* Known major fetal anomalies\n* Intrauterine fetal demise (IUFD)\n* Contraindication to vaginal delivery\n* Known hypersensitivity to carbetocin, misoprostol, or oxytocin\n* Known coagulation disorders requiring alternative management\n* Planned cesarean delivery\n* Participation in another interventional study that may affect postpartum bleeding outcomes",{"count":306,"type":22},146,[25],"Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide, particularly among women with known risk factors. Uterotonic agents are routinely administered after vaginal delivery to prevent excessive bleeding. Carbetocin, a long-acting oxytocin analogue, and misoprostol are both used for this purpose, but comparative data in high-risk vaginal deliveries remain limited.\n\nThis prospective randomized study aims to compare the effectiveness and safety of intravenous carbetocin versus rectal misoprostol for the prevention of postpartum hemorrhage in women with risk factors undergoing vaginal delivery at Galilee Medical Center. The primary outcome is the incidence of postpartum hemorrhage. Secondary outcomes include the need for additional uterotonic agents or surgical interventions, changes in hemoglobin levels, blood transfusion requirements, and maternal adverse effects.",[28,93],[311],"Postpartum hemorrhage, Carbetocin, Misoprostol, Vaginal delivery, Uterotonic agents, High-risk pregnancy","2026-01-13",{"date":314,"type":40},"2026-01-20",{"date":316,"type":22},"2026-01-31",{"date":318,"type":22},"2028-01-01",{"name":320,"class":321},"Western Galilee Hospital-Nahariya","OTHER_GOV",{"id":323,"slug":324,"hasResults":11,"nctId":325,"briefTitle":326,"officialTitle":327,"acronym":328,"eligibilityCriteria":329,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":330,"enrollmentInfo":331,"targetDuration":4,"studyType":23,"phases":333,"briefSummary":334,"conditions":335,"keywords":338,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":345,"lastUpdatePostDateStruct":346,"startDateStruct":348,"completionDateStruct":350,"leadSponsor":352,"locationsCount":354},"100580866","rhode-island---statewide-postpartum-hypertension-remote-surveillance-100580866","NCT06842875","Rhode Island - Statewide Postpartum Hypertension Remote Surveillance","Effect of a Technology-based Collaborative Model on Persistent Hypertension and Preventive Care Attendance Among Postpartum People With Hypertensive Disorders of Pregnancy","RI-SPHERES","Inclusion Criteria:\n\n* Postpartum patient aged 18 years or more at any birthing hospital in Rhode Island\n* Diagnosed during pregnancy or after delivery with hypertensive disorder of pregnant\n* English-, Spanish-, Portuguese-, or Haitian-Creole-speaking\n* Smartphone ownership\n\nExclusion Criteria:\n\n* Prior enrollment in this trial\n* Prisoners or incarcerated people\n* Inability or unwillingness to provide informed consent\n* Inability to communicate with study team, despite an interpreter","60 Years",{"count":332,"type":22},1536,[25],"This is a hybrid type 1 non-inferiority implementation effectiveness trial among postpartum patients with hypertension (N=1536) that will test the hypothesis that RI-SPHERES (a technologically enabled collaborative care model) is non-inferior to a standard self-measured blood pressure program in terms of persistent hypertension at six weeks postpartum and preventive care receipt within one year of delivery.",[336,337,28],"Hypertension in Pregnancy","Postpartum Preeclampsia",[339,340,341,342,343,344],"postpartum hypertensive disorders of pregnancy","postpartum preeclampsia","digital health","collaborative care model","population health","self-measured blood pressure","2025-06-12",{"date":347,"type":40},"2025-06-17",{"date":349,"type":40},"2025-04-15",{"date":351,"type":22},"2029-03-01",{"name":353,"class":47},"Women and Infants Hospital of Rhode Island",5]