[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postpartum\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postpartum":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,38,0,25,[9,52,81,105,126,152,181,210,234,270,306,329,355,381,407,431,458,481,501,534,558,580,620,651,682],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100053713","facilitated-transitions-from-postpartum-to-primary-care-coordination-for-people-with-chronic-conditions-100053713",false,"NCT06557005","Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions","Bridges to Primary Care: Transforming Postpartum Primary Care Coordination for People With Chronic Conditions","Inclusion Criteria\n\n* Receiving obstetric care at an MGH-affiliated obstetrics practice (except for the MGH HOPE Clinic, which has a unique care model that provides prenatal and postnatal care for individuals with substance use disorder, including the provision of primary care through 2+ years postpartum)\n* Pregnant with a live fetus or delivered a live-born neonate ≥24 weeks of gestation, based on the clinical estimate of gestational age\n* If postpartum, has a neonate that is currently living at the time of enrollment\n* Has one or more of the following conditions listed in the \"Problem List,\" \"Medical History,\" or clinical notes during prenatal, intrapartum, or postpartum encounters in the EHR (or in the case of BMI, the patient's anthropometric measurements):\n\n  * Chronic or essential hypertension\n  * Hypertensive disorders related to pregnancy (e.g., pre-eclampsia)\n  * Type 1 or 2 diabetes (i.e., pre-existing diabetes)\n  * Gestational diabetes\n  * Class II Obesity (pre-pregnancy body mass index ≥35 kg\u002Fm2; or if pre-pregnancy body mass index is not known, a first trimester BMI of ≥35 kg\u002Fm2)\n  * Depression or anxiety disorder\n* Has a primary care clinician listed in the patient's medical record\n* Has access to or agrees to be enrolled in the electronic health record patient portal and consents to be contacted via these modalities\n* Able to read\u002Fspeak English or Spanish language\n* Is age ≥18 years old\n\nExclusion Criteria\n\n• Any individual not meeting all inclusion criteria","FEMALE","18 Years",{"count":20,"type":21},1320,"ESTIMATED","INTERVENTIONAL",[24],"NA","The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the \\>30% of pregnant people who have or are at risk for these conditions. This study aims to increase postpartum primary care engagement, quality, and experience by strengthening postpartum transitions to primary care using a behavioral economics-informed, multi-component intervention integrated into usual inpatient postpartum care. Using a randomized controlled trial and repeated outcome assessments through administrative and survey data, this study will generate rigorous, actionable evidence to ensure primary care coordination becomes standard postpartum care practice, potentially catalyzing sustained primary care engagement throughout life.",[27,28,29,30,31,32,33],"Hypertension","Diabetes","Postpartum","Pregnancy","Anxiety","Depression","Obesity",[35,36,37,38],"Postpartum Care","Primary Care","Care Transitions","Chronic Disease","RECRUITING","2026-07-09",{"date":42,"type":43},"2026-07-13","ACTUAL",{"date":45,"type":43},"2025-05-23",{"date":47,"type":21},"2028-05-23",{"name":49,"class":50},"Massachusetts General Hospital","OTHER",1,{"id":53,"slug":54,"hasResults":12,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":17,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":51},"100625189","acute-effects-of-radiofrequency-diathermy-in-postpartum-women-with-diastasis-abdominis-100625189","NCT07419399","Acute Effects of Radiofrequency Diathermy in Postpartum Women With Diastasis Abdominis","RDPP","Inclusion Criteria:\n\n* Age between 20 and 45 years old.\n* BMI between 18.5 and 29.9 kg\u002Fmw.\n* Postpartum period between 6 months and 1 year Additionally, in the group of women with RAD, pathological RAD will be defined as an inter-rectus distance greater than 2.2 cm (measured 3 cm above the navel), according to the criteria of Beer et al. (2009)\n\nExclusion Criteria:\n\n* Previous surgeries involving the abdominal wall.\n* Cesarean deliveries.\n* Women diagnosed with chronic pain",true,"20 Years","45 Years",{"count":63,"type":21},48,[24],"This clinical trial aims to compare the immediate tissue response in postpartum women with and without rectus abdominis diastasis (RAD) after undergoing radiofrequency diathermy (RFD) treatment. The main question it seeks to answer is: Do postpartum women with and without RAD exhibit different acute tissue responses in terms of pressure pain threshold, superficial thermal sensitivity, and tissue elasticity? To determine whether there are differences in these acute tissue responses between the groups, researchers will compare RFD with a sham RFD intervention in postpartum women with and without RAD.\n\nParticipants will receive one session of either RFD or a sham RFD intervention and will complete three assessments: one at baseline and two after the intervention, one immediately afterwards and one 20 minutes afterwards.",[29,67],"Rectus Muscle Diastasis",[69,70,71],"rectus abdominis diastasis","radiofrequency diathermy","postpartum","2026-06-22",{"date":74,"type":43},"2026-06-25",{"date":76,"type":43},"2026-03-30",{"date":78,"type":21},"2029-03-30",{"name":80,"class":50},"University of Valencia",{"id":82,"slug":83,"hasResults":12,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100600948","substance-use-in-pregnant-people---optimizing-retention-in-treatment-100600948","NCT07104123","Substance Use in Pregnant People - Optimizing Retention in Treatment","Substance Use in Pregnant People - Optimizing Retention in Treatment by Maximizing Opportunities for Management","SUPPORT-MOM","Inclusion Criteria:\n\nConfirmed viable intrauterine pregnancy at any gestational age, or within three years postpartum\n\nSUD as defined in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders or clinician documentation\n\nExclusion Criteria:\n\nDecline follow-up care at study site\n\nRequire immediate hospitalization for unstable medical or psychiatric conditions making them clinically unsuitable to participate in a research study",{"count":90,"type":21},40,[24],"Substance use during pregnancy is a leading cause of maternal morbidity and mortality in the United States, with 55-80% of postpartum patients disengaging from substance use disorder (SUD) treatment within one year of delivery. Structural and social determinants of health, including housing instability, transportation barriers, and limited childcare access, further exacerbate disparities in treatment retention.\n\nThis pilot study, conducted in two specialized prenatal care clinics, evaluates the feasibility and acceptability of two integrated strategies to promote sustained engagement in recovery-oriented services during the perinatal and postpartum periods. Aim 1 implements a standardized social needs screening and referral protocol to connect patients with community-based supports. Aim 2 pilots a contingency management intervention to incentivize recovery-supportive behaviors.\n\nFindings will inform the design of a larger multi-site randomized controlled trial to evaluate the impact of these interventions on treatment retention, overdose prevention, and maternal-infant health outcomes.",[94,30,29,95],"Substance Use Disorder (SUD)","Contingency Management","2026-06-17",{"date":72,"type":43},{"date":99,"type":43},"2026-02-02",{"date":101,"type":21},"2027-09",{"name":103,"class":50},"Washington University School of Medicine",2,{"id":106,"slug":107,"hasResults":12,"nctId":108,"briefTitle":109,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":111,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":115,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":51},"100586238","novel-visual-education-tool-to-improve-recognition-and-reporting-of-postpartum-urgent-maternal-warning-signs-100586238","NCT06912776","Novel Visual Education Tool to Improve Recognition and Reporting of Postpartum Urgent Maternal Warning Signs","Inclusion Criteria:\n\n* Postpartum women\n* Nulliparity\n* Age \\>18 years of age\n* English speaking patients\n\nExclusion Criteria:\n\n* Inability to provide informed written consent\n* Refusal to participate in all study-related procedures\n* Patients not fluent in English\n* Patients with current or history of serious peripartum complications and\u002For events - such as DVT, PE, peripartum cardiomyopathy, etc. (in which the patient may have received more than standard clinical counseling)\n* Patient with comorbidities that potentially require anticoagulation i.e. coagulopathies and may be more prone to DVTs\n* Patients with uncorrected visual or hearing impairment\n* Healthcare providers (in which patients will have significant background knowledge)",{"count":90,"type":21},[24],"This study aims to create a novel visual education tool that builds on the urgent maternal warning signs identified by The Council on Patient Safety in Women's Health Care. Including effective images will improve the understanding of these grave warning signs\u002Fsymptoms, improving anatomical accuracy while remaining simplistic for patients of varying levels of health care literacy. The investigative team will be focusing on urgent warning signs pertinent to the postpartum period.",[29],[30,29,116],"nulliparus","2026-06-09",{"date":119,"type":43},"2026-06-10",{"date":121,"type":43},"2025-06-20",{"date":123,"type":21},"2027-07",{"name":125,"class":50},"Northwestern University",{"id":127,"slug":128,"hasResults":12,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":4,"eligibilityCriteria":132,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":133,"enrollmentInfo":134,"targetDuration":4,"studyType":22,"phases":136,"briefSummary":137,"conditions":138,"keywords":139,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":51},"100643227","comparative-effects-of-hypopressive-and-transverses-abdominis-focused-core-training-in-postpartum-100643227","NCT07576283","Comparative Effects of Hypopressive and Transverses Abdominis Focused Core Training in Postpartum","Comparative Effects of Hypopressive and Transverses Abdominis Focused Core Training on Urinary Incontinence, Pelvic Floor Function and Quality of Life in Postpartum","Inclusion Criteria:\n\n* Multiparous women with urinary incontinence\n* Who had undergone normal vaginal delivery\n* Free from any medical and gynecological risk factors and \u002For conditions\n* Stress urinary incontinence test is positive: Pad test\n\nExclusion Criteria:\n\n* Had neurological impairments or connective tissue disorders\n* Active urinary or vaginal infection in the past 3 months\n* Had known detrusor instability\n* Had undergone previous surgery to alleviate SUI\n* Had pelvic organ prolapse","35 Years",{"count":135,"type":21},60,[24],"The study aims to compare the effectiveness of these two core training approaches in improving urinary incontinence, pelvic floor function, and quality of life in postpartum women.",[29],[140,141,142,71,143],"urinary incontinence","pelvic floor function","quality of life","female","2026-06-08",{"date":117,"type":43},{"date":147,"type":43},"2025-10-01",{"date":149,"type":21},"2026-08-01",{"name":151,"class":50},"Riphah International University",{"id":153,"slug":154,"hasResults":12,"nctId":155,"briefTitle":156,"officialTitle":157,"acronym":4,"eligibilityCriteria":158,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":159,"targetDuration":4,"studyType":22,"phases":161,"briefSummary":162,"conditions":163,"keywords":168,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":51},"100638371","postpartum-exercise-intervention-100638371","NCT07613333","Postpartum Exercise Intervention","Influence of a Supervised Postpartum Exercise Program on Maternal Physical Activity Levels and Musculoskeletal Health","Inclusion Criteria:\n\n* 18 years of age or older\n* gave birth in the 24 months prior to study enrollment\n\nExclusion Criteria:\n\n* less than 6 weeks postpartum or not medically appropriate to engage in exercise regardless of time since childbirth (will be screened using the Get Active Questionnaire for Postpartum)\n* prescription anti-inflammatory\u002Fpain medications that are taken daily;\n* significant orthopedic conditions that would contraindicate performance of the fatigue task and participation in the exercise intervention (such as fractures, severe scoliosis, etc)\n* moderate to severe cardiovascular \\&\u002For pulmonary disease that contraindicates participation in exercise\n* neuromuscular health conditions (such as diabetes, neuropathy, multiple sclerosis, stroke, seizures, etc);\n* smoking\u002Fvaping or use of other tobacco or nicotine products (chewing tobacco, nicotine patches, nicotine gum, etc.)\n* use of any illegal drugs",{"count":160,"type":21},50,[24],"The postpartum period is associated with decreases in physical activity levels, muscular strength, muscular endurance, and pelvic floor muscle function, but little scientific evidence exists on how best to initiate and progress exercise in the postpartum period. This proposal aims to improve habitual physical activity levels, neuromuscular health (i.e., strength, fatigability, symptom burden) and overall wellbeing (i.e., decreased fear of movement, improved sleep quality, improved perception of quality of life) through participation in a weekly exercise program. This study will help to inform postpartum exercise recommendations and is novel as it allows participants to incorporate their children into the exercise routine, thus removing a primary barrier to physical activity\u002Fexercise.",[29,164,165,166,167],"Neuromuscular Adaptations","Abdominal Muscles","Pelvic Floor Dysfunctions","Physical Activity",[169,170,171],"postpartum physical activity","postpartum neuromuscular function","postpartum exercise","2026-05-21",{"date":174,"type":43},"2026-05-29",{"date":176,"type":43},"2026-02-19",{"date":178,"type":21},"2028-08",{"name":180,"class":50},"Carroll University",{"id":182,"slug":183,"hasResults":12,"nctId":184,"briefTitle":185,"officialTitle":186,"acronym":187,"eligibilityCriteria":188,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":189,"targetDuration":4,"studyType":22,"phases":191,"briefSummary":192,"conditions":193,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":201,"startDateStruct":203,"completionDateStruct":205,"leadSponsor":207,"locationsCount":104},"100626071","the-recover-study---postpartum-recovery-of-pelvic-floor-structures-and-the-impact-of-early-rehabilitation-100626071","NCT07430865","The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early Rehabilitation","The RECOVER Study - Recovery of Pelvic Floor Structure and Function After Vaginal Childbirth- a Longitudinal Cohort Study With an Embedded Pilot Trial","RECOVER","Inclusion Criteria:\n\n* Individuals (over 18 years) who delivered a single child vaginally between 37 and 41 weeks of gestation, with a birthweight of at least 2500 grams.\n\nExclusion Criteria:\n\n* Delivered via c-section\n* Multiparous with previous third- or fourth-degree tears\n* History of major urogynecological surgery\n* Known neurological disorder (e.g., stroke, multiple sclerosis) that could affect the assessment outcomes\n* Severe connective tissue disorders that could affect the assessment outcomes\n* New pregnancy of more than 6 weeks during the study period\n* Pain with vaginal penetration, tampon use, or gynecological examinations that would prevent participation in assessments\n* Visible signs for wound complications assessed via REEDA tool (redness, oedema, ecchymosis, discharge, approximation) will exclude the participants from the first ultrasound assessment and vaginal palpation.",{"count":190,"type":21},380,[24],"The goal of this observational study with an embedded pilot clinical trial is to learn how the pelvic floor recovers after vaginal childbirth and whether early individualized pelvic floor muscle training can improve recovery in people who experience pelvic floor symptoms after vaginal delivery. The main questions it aims to answer are:\n\n* How do pelvic floor muscles and surrounding tissues change and recover during the first year after vaginal childbirth?\n* How are these structural changes and their recovery related to urinary, bowel, and vaginal symptoms?\n* In participants with pelvic floor symptoms after vaginal childbirth, does early individualized pelvic floor muscle training improve symptoms and support structural recovery compared with usual care?\n\nResearchers will compare participants who receive the early pelvic floor muscle training to those receiving standard postpartum care to see if the training helps improve pelvic floor function and reduce symptoms.\n\nParticipants will:\n\nAttend clinic visits at six weeks, and six months after childbirth\n\nComplete questionnaires about urinary, bowel, and vaginal symptoms, as well as physical activity and quality of life at six weeks, and four, six months, and twelve months after childbirth\n\nUndergo clinical pelvic floor assessments, including vaginal palpation of muscle strength, tone, and perineal body stability\n\nHave ultrasound examinations of the pelvic floor to assess muscle structure, tissue integrity, and perineal body morphology\n\nFor those in the pilot trial, participate in an early, individualized pelvic floor muscle training program\n\nThis study will provide important information about how the pelvic floor heals after childbirth, how structural changes are linked to symptoms, and whether early personalized training can help prevent long-term problems.",[194,195,196,29,197,198,199,200],"Urinary Incontinence","Pelvic Organ Prolapse (POP)","Bowel Symptoms","Physiotherapy and Rehabilitation","Pelvic Floor Muscle Training","Pelvic Floor","Recovery",{"date":202,"type":43},"2026-05-27",{"date":204,"type":43},"2026-04-07",{"date":206,"type":21},"2029-12-31",{"name":208,"class":209},"Vastra Gotaland Region","OTHER_GOV",{"id":211,"slug":212,"hasResults":12,"nctId":213,"briefTitle":214,"officialTitle":215,"acronym":4,"eligibilityCriteria":216,"healthyVolunteers":12,"sex":17,"minAge":60,"maxAge":217,"enrollmentInfo":218,"targetDuration":4,"studyType":22,"phases":219,"briefSummary":220,"conditions":221,"keywords":4,"overallStatus":224,"whyStopped":4,"lastUpdateSubmitDate":225,"lastUpdatePostDateStruct":226,"startDateStruct":228,"completionDateStruct":230,"leadSponsor":232,"locationsCount":4},"100636060","online-delivered-core-stability-exercises-in-postpartum-women-100636060","NCT07560774","Online-Delivered Core Stability Exercises in Postpartum Women","Effects of Online-Delivered Core Stability Exercises on Postural Control and Trunk Endurance in Postpartum Women","Inclusion Criteria:\n\n1. singleton pregnancy;\n2. medically uncomplicated delivery;\n3. clearance from a healthcare provider to participate in low- to moderate-intensity exercise;\n4. self-reported difficulties with trunk endurance, balance, or early fatigue during daily activities.\n\nExclusion Criteria:\n\n1. unresolved obstetric complications;\n2. severe pelvic floor dysfunction requiring specialized medical management; (3) neurological or musculoskeletal conditions affecting balance\n\n(4) participation in structured core training more than once per week during the previous three months.","40 Years",{"count":90,"type":21},[24],"This study will examine a 12-week online core stability program for postpartum women, where participants will complete supervised sessions three times per week and will be compared with an education-only group. The intervention group will participate in supervised, real-time sessions via a video-conferencing platform, three times per week for 12 weeks. Exercises combine isometric and dynamic core stability tasks, progressing in difficulty over time. Dynamic postural control will be assessed using the lower quarter Y-Balance Test (YBT-LQ), while trunk endurance will be measured using the flexor endurance, extensor endurance, and side bridge tests.",[29,222,223],"Trunk Muscle Endurance","Postural Stability","NOT_YET_RECRUITING","2026-04-28",{"date":227,"type":43},"2026-05-01",{"date":229,"type":21},"2026-06-01",{"date":231,"type":21},"2027-02-01",{"name":233,"class":50},"Prince Sattam Bin Abdulaziz University",{"id":235,"slug":236,"hasResults":12,"nctId":237,"briefTitle":238,"officialTitle":239,"acronym":240,"eligibilityCriteria":241,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":242,"targetDuration":4,"studyType":244,"phases":4,"briefSummary":245,"conditions":246,"keywords":250,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":263,"completionDateStruct":265,"leadSponsor":267,"locationsCount":269},"100598171","organ-dysfunction-score-for-obstetric-patients-100598171","NCT07068022","Organ Dysfunction Score for Obstetric Patients","Development and Validation of an Obstetric Organ Dysfunction Score to Predict Mortality in Intensive Care Unit: A Multicenter, Prospective, Cohort Study","SOFA-OBS","Inclusion Criteria:\n\nAll of the following=\n\n* Pregnant (at any gestational age) or post-partum patients (at ≤3 days postpartum)\n* ≥ 18 years old\n* Requiring admission to ICU for any reason\n* Staying in the ICU for ≥ 24h\n* Giving her consent to participate. Patients will be recruited consecutively until reaching the sample size.\n\nExclusion Criteria:\n\nAny of the following=\n\n* Patients \\\u003C18 years old\n* Non-pregnant patients\n* ≥ 4 days postpartum\n* Patients or surrogates not giving consent to participate\n* ICU-LOS \\\u003C 24 h",{"count":243,"type":21},130,"OBSERVATIONAL","The goal of this observational study is to develop and evaluate an organ dysfunction score adapted to pregnancy and early puerperium (SOFA-OBS) that also incorporates a non-invasive tool to evaluate respiratory function (pulse oximeter).\n\nThe main question it aims to answer is: Does an organ dysfunction score adapted to pregnant and postpartum patients have a higher capacity to predict mortality than a non-adjusted organ dysfunction score? Participants: Patients requiring ICU (Intensive Care Units) admission, who are either pregnant or postpartum (up to 3 days after giving birth). The investigators aimed to include 130 participants.\n\nThe investigators will only collect participants' data and laboratory results that ICU doctor usually need for clinical practice. No additional interventions are required. Moreover, the investigators will evaluate if measuring participants' oxygenation through a non-invasive tool (pulse oximeter) is equally effective as measuring oxygenation by an arterial puncture.\n\nBackground: When managing severely ill patients in ICU, the investigators often use what it is called scores. Scores refer to a numerical value assigned to a patient's condition, which often predict outcome. The Sequential Organ Failure Assessment (SOFA) score is a scoring system that assess severity of organ dysfunction (in liver, kidney, blood pressure, respiratory, neurologic and platelets). It also identifies patients with severe infections (sepsis) and patients with bad outcomes.\n\nPatients undergoing pregnancy or early postpartum develop physiological changes, such us a decrease in creatinine (a laboratory test measuring kidney function) and a decrease in blood pressure during the second trimester. These changes are not considered by the SOFA score. Actually, there is not an organ dysfunction score adapted to pregnant\u002Fpostpartum patients to be used in the ICU. Moreover, a blood sample taken by arterial puncture is required to evaluate respiratory function by the SOFA score, which is a painful procedure. Instead, the investigators could evaluate respiratory function using a pulse oximeter, which measures peripheral oxygen saturation without needing an arterial puncture.\n\nPotential benefits: A SOFA-OBS would hopefully become a more precise tool than general SOFA to evaluate organ dysfunction and to predict outcome among these patients. It would also help to detect sepsis earlier and treat it promptly, which might help reducing its mortality.",[30,29,247,248,249],"Organ Dysfunction","Critical Care, Intensive Care","Sepsis",[251,30,29,252,253,254,255,256,257,258,249,259,260],"Sequential Organ Failure Assessment score","Critical care","Intensive Care Unit","Creatinine","Peripheral oxygen saturation","Hypotension","Maternal mortality","Mortality","Septic shock","Multicenter study","2026-04-22",{"date":225,"type":43},{"date":264,"type":43},"2025-10-06",{"date":266,"type":21},"2027-02-28",{"name":268,"class":50},"Daniela Vasquez",18,{"id":271,"slug":272,"hasResults":12,"nctId":273,"briefTitle":274,"officialTitle":275,"acronym":4,"eligibilityCriteria":276,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":277,"enrollmentInfo":278,"targetDuration":280,"studyType":244,"phases":4,"briefSummary":281,"conditions":282,"keywords":285,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":296,"lastUpdatePostDateStruct":297,"startDateStruct":299,"completionDateStruct":301,"leadSponsor":303,"locationsCount":51},"100576721","external-trigeminal-nerve-stimulation-for-migraine-treatment-in-pregnancy-100576721","NCT06788977","External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy","CEFALY Pregnancy Registry","Inclusion Criteria:\n\n1. Patients willing and able to provide simple consent for registry participation.\n2. Has access to email, text messages via smartphone or computer with internet access\n3. Be between the ages of 18 to 44 years at enrollment.\n4. Pregnant with one fetus\u002Fbaby at time of enrollment (singleton pregnancy)\n5. Have headaches or migraines prior to pregnancy and continued to have headaches or migraines into pregnancy OR headaches or migraines began while pregnant in the first trimester.\n6. Able to provide proof of active intrauterine pregnancy and estimated due date, via online document upload, using any of the following documents:\n\n   1. ultrasound report of current pregnancy\n   2. beta hcg lab report\n   3. a signed provider's medical documentation confirming intrauterine pregnancy with fetal heart sounds and estimated due date\n   4. a signed provider's note on a prescription sheet or physician letterhead confirming intrauterine pregnancy and estimated due date\n\nExclusion Criteria:\n\n1. Patients under the age of 18 or over the age of 44 at enrollment\n2. Not pregnant at time of enrollment\n3. Pregnant with more than one fetus\u002Fbaby at time of enrollment (multigestational pregnancy)\n4. Patients with any other condition which might preclude participation in the opinion of the patient's physician(s) or the study's principal investigator\n5. No access to email, smartphone, or computer with internet access","44 Years",{"count":279,"type":21},550,"12 Months","This online registry aims to understand the potential benefits and safety of external trigeminal nerve stimulation for the treatment of migraine in pregnant women. Women do not need to use external trigeminal nerve stimulation or any other form of migraine treatment to participate in the registry.\n\nThe main question it aims to answer is:\n\nIs external trigeminal nerve stimulation a safe and effective option for migraine treatment during and after pregnancy?\n\nThere are no required changes in migraine treatment to participate in this registry. Participants may or may not use external trigeminal nerve stimulation or any other treatment they currently use and may still participate in the registry. There are no clinic or research visits, as the registry is entirely online. Participants will be asked to complete up to six 15- 20-minute surveys over a time period of up to 12 months.",[30,283,284,29,32,31],"Migraine","Headache",[30,283,284,286,287,288,29,289,290,291,292,293,294,295],"Neuromodulation","Trigeminal Nerve Stimulation","External Trigeminal Nerve Stimulation","drug-free","medications","complementary therapy","alternative therapy","wholistic therapy","natural","non-invasive device","2026-04-13",{"date":298,"type":43},"2026-04-15",{"date":300,"type":43},"2024-11-25",{"date":302,"type":21},"2030-12",{"name":304,"class":305},"Cefaly Technology","INDUSTRY",{"id":307,"slug":308,"hasResults":12,"nctId":309,"briefTitle":310,"officialTitle":311,"acronym":4,"eligibilityCriteria":312,"healthyVolunteers":12,"sex":17,"minAge":60,"maxAge":313,"enrollmentInfo":314,"targetDuration":4,"studyType":22,"phases":315,"briefSummary":316,"conditions":317,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":320,"lastUpdatePostDateStruct":321,"startDateStruct":323,"completionDateStruct":325,"leadSponsor":327,"locationsCount":51},"100537934","telehealth-diaphragmatic-vs-pelvic-exercise-in-postpartum-pregnancy-related-pelvic-girdle-pain-100537934","NCT06284278","Telehealth: Diaphragmatic vs. Pelvic Exercise in Postpartum Pregnancy-related Pelvic Girdle Pain","Comparison of Diaphragmatic Breathing Exercise and Pelvic Stabilization Exercise in Postpartum Women With Pregnancy-related Pelvic Girdle Pain: A Real-time Telehealth-based Intervention","Inclusion Criteria:\n\n* Age between 20-65 years\n* Postpartum ≥ 3 months\n* Pain located in sacroiliac joints (i.e., pain located between the posterior iliac crest and gluteal fold)\n* Pregnancy-related cause of pelvic pain that pain occurs during pregnancy or after delivery (i.e., not traumatic or degenerative cause)\n* At least 2 positive findings of 6 pain provocation tests for pelvic pain\n* Score of Active Straight Leg Rise (ASLR) test \\> 0\n\nExclusion Criteria:\n\n* being pregnant or actively trying to get pregnant\n* having known causes of pelvic girdle pain, such as fractures and rheumatism\n* having undergone lumbar, pelvic, gynecologic or obstetric surgery\n* having current neurological symptoms and signs in lower extremities such as lumbar radiculopathy and myelopathy\n* having cancer\n* having cardiovascular disease\n* being diagnosed as having a psychiatric disease\n* active infection or infectious disease in the pelvis or abdomen\n* having experience with structured and supervised core or trunk exercise training programs.","65 Years",{"count":135,"type":21},[24],"The goal of this interventional study is to compare investigate the short-term and long-term effects of 8-week real-time telehealth-based diaphragmatic breathing exercise and pelvic stabilization exercise on pain, disability, and quality of life in postpartum women with pregnancy-related pelvic girdle pain.",[29,318,319],"Pregnancy Related","Pelvic Girdle Pain","2026-04-06",{"date":322,"type":43},"2026-04-08",{"date":324,"type":43},"2024-03-01",{"date":326,"type":21},"2026-07-31",{"name":328,"class":50},"YI-JU TSAI",{"id":330,"slug":331,"hasResults":12,"nctId":332,"briefTitle":333,"officialTitle":334,"acronym":335,"eligibilityCriteria":336,"healthyVolunteers":59,"sex":337,"minAge":18,"maxAge":4,"enrollmentInfo":338,"targetDuration":4,"studyType":244,"phases":4,"briefSummary":340,"conditions":341,"keywords":343,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":347,"lastUpdatePostDateStruct":348,"startDateStruct":349,"completionDateStruct":351,"leadSponsor":352,"locationsCount":354},"100611642","impact-of-vaccine-funding-by-the-national-health-insurance-on-vaccination-coverage-among-patients-targeted-by-current-vaccination-recommendations-and-followed-in-outpatient-consultations-100611642","NCT07243236","Impact of Vaccine Funding by the National Health Insurance on Vaccination Coverage Among Patients Targeted by Current Vaccination Recommendations and Followed in Outpatient Consultations","\"Assessment of the Impact of Vaccine Funding by the National Health Insurance on Vaccination Coverage Among Patients Targeted by Current Vaccination Recommendations and Followed in Outpatient Consultations in Ile-de-France Region in France\"\"","VAXINOVA","Inclusion Criteria:\n\nFor patients:\n\n1. For the assessment of pneumococcal coverage among patients eligible for this vaccination:\n\n   * Individuals aged 18 years or older,\n   * Individuals followed in outpatient consultations within a department and healthcare institution participating in the project;\n   * Individuals eligible for pneumococcal vaccination against according to current French recommendations,\n   * Individuals meeting the eligibility conditions and receiving care under long-term illness coverage (ALD) or benefiting from complementary universal health coverage (C2S) or state medical aid (AME).\n2. For the assessment of pertussis vaccination among pregnant women:\n\n   * Women aged 18 years or older,\n   * Women who have had at least one follow-up outpatient consultation from 20 weeks of gestation in a maternity ward participating in the project,\n   * Women in the immediate postpartum period (during their maternity stay) who have given birth to one or more live children and delivered after 36 weeks of gestation,\n   * Women who have declared their pregnancy and are covered under maternity insurance (i.e., from the first day of the sixth month of pregnancy until the 12th day after delivery).\n\nFor healthcare professionals: all vaccinating healthcare providers working in a participating department or center.\n\nExclusion Criteria:\n\n* Individuals seen in settings other than outpatient consultations (day hospital, week hospital, conventional hospitalization, International Vaccination Center).","ALL",{"count":339,"type":21},2920,"The objective of our study is to evaluate the impact of vaccine funding for patients seen in outpatient consultations within four healthcare institutions in the Ile-de-France region in France, made possible through the establishment of a tripartite agreement between the hospital group, the Île-de-France Regional Health Agency (ARS IDF), and the Primary Health Insurance Fund (CPAM).",[342,29],"Healthcare Providers",[344,345,346],"Vaccine coverage","Vaccine funding within healthcare institutions","Outpatient consultations","2026-04-02",{"date":322,"type":43},{"date":350,"type":43},"2025-11-19",{"date":123,"type":21},{"name":353,"class":50},"Assistance Publique - Hôpitaux de Paris",6,{"id":356,"slug":357,"hasResults":12,"nctId":358,"briefTitle":359,"officialTitle":360,"acronym":4,"eligibilityCriteria":361,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":362,"targetDuration":4,"studyType":22,"phases":364,"briefSummary":365,"conditions":366,"keywords":368,"overallStatus":224,"whyStopped":4,"lastUpdateSubmitDate":372,"lastUpdatePostDateStruct":373,"startDateStruct":375,"completionDateStruct":377,"leadSponsor":379,"locationsCount":51},"100627438","the-effect-of-postpartum-mandala-coloring-on-anxiety-fatigue-maternal-attachment-and-breastfeeding-self-efficacy-100627438","NCT07448636","The Effect of Postpartum Mandala Coloring on Anxiety, Fatigue, Maternal Attachment and Breastfeeding Self-efficacy","The Effect of Mandala Coloring on Anxiety, Fatigue, Maternal Attachment, and Breastfeeding Self-Efficacy in the Postpartum Period: A Randomized Controlled Experimental Study","Inclusion Criteria:\n\n* Being 18 years of age or older\n* Having had a cesarean delivery after the 37th week of gestation\n* The baby being with the mother and the mother being able to breastfeed\n* Volunteering to participate in the study\n* Having a planned cesarean section\n\nExclusion Criteria:\n\n* The mother is currently or has previously received psychiatric treatment.\n* The mother has a physical disability in her upper extremities.\n* The mother has a vision problem.\n* The newborn has a congenital anomaly.\n* The newborn experienced an obstetric complication requiring immediate hospitalization after birth (hemorrhage, infection, bladder damage, preeclampsia, etc.).\n\nCriteria for terminating the study:\n\n* The baby or mother has a medical condition requiring hospitalization within 6 weeks postpartum.\n* Communication with the mother is not possible within 6 weeks postpartum",{"count":363,"type":21},140,[24],"The aim of this study is to investigate the effects of mandala coloring on anxiety, fatigue, breastfeeding self-efficacy, and mother-infant bonding in postpartum mothers. The sample consists of women who have had a cesarean section at Kayseri City Hospital within the last year. Data will be collected using a Personal Information Form, the Postpartum Specific Anxiety Scale, the Short Form of the Breastfeeding Self-Efficacy Scale, the Chalder Fatigue Scale, and the Maternal Attachment Scale. Mothers meeting the inclusion criteria will be randomly assigned to intervention and control groups. Mothers in the intervention group will be informed that they will begin mandala coloring one week after their cesarean delivery. They will be asked to color a mandala twice a week for a total of 5 weeks, with each coloring session lasting 30 minutes. To eliminate the possibility of mothers forgetting to color the mandala, the researcher will send reminder messages twice a week starting from the end of the first week. The Personal Information Form will be collected through face-to-face interviews while the mothers are in the hospital. Mothers in the control group will receive routine hospital care and will not paint mandalas. Researchers will call all mothers at the end of weeks 1 and 2 to administer the Postpartum Specific Anxiety Scale and the Short Form of the Breastfeeding Self-Efficacy Scale, and at the end of weeks 4 and 6 to administer questions from the Postpartum Specific Anxiety Scale, Short Form of the Breastfeeding Self-Efficacy Scale, Chalder Fatigue Scale, and Maternal Attachment Scale, recording their responses.",[367,29],"Mandala Coloring",[367,71,31,369,370,371],"Fatigue","Maternal Attachment","Breastfeeding Self-Efficacy","2026-02-26",{"date":374,"type":43},"2026-03-04",{"date":376,"type":21},"2026-03-15",{"date":378,"type":21},"2026-12-31",{"name":380,"class":50},"Nuh Naci Yazgan University",{"id":382,"slug":383,"hasResults":12,"nctId":384,"briefTitle":385,"officialTitle":386,"acronym":4,"eligibilityCriteria":387,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":277,"enrollmentInfo":388,"targetDuration":4,"studyType":22,"phases":390,"briefSummary":391,"conditions":392,"keywords":393,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":398,"lastUpdatePostDateStruct":399,"startDateStruct":401,"completionDateStruct":403,"leadSponsor":405,"locationsCount":51},"100504539","mobile-application-based-exercise-intervention-for-pregnant-women-100504539","NCT05849649","Mobile Application-based Exercise Intervention for Pregnant Women","Increasing Physical Activity Through a Mobile Health Intervention Among Pregnant and Postpartum Women in a Rural Setting","Inclusion Criteria:\n\n* Age 18-44\n* Confirmed singleton viable pregnancy\n* English-Speaking (the app is currently only available in English)\n* Physician release to participate in exercise prior to study participation\n* Ownership of a smartphone\n* Patient at either Graves Gilbert Clinic or Women's Health Specialists\n* Plans to deliver at The Medical Center in Bowling Green, KY.\n\nExclusion Criteria:\n\n* Multiple gestation pregnancy\n* Inability to provide voluntary informed consent\n* Any medical condition (pregnancy-related or not) that would preclude exercise.",{"count":389,"type":21},176,[24],"The overarching goal of this randomized controlled clinical trial is to test the efficacy of the mHealth app (BumptUp) for improving physical activity levels among pregnant and postpartum women in a rural setting. Secondary outcomes include weight status, dietary intake, glucose tolerance, blood pressure, and mental health.\n\nSpecific Aim 1. Conduct an RCT (N=176) to assess the efficacy of the mHealth intervention for increasing physical activity levels during pregnancy (13-15, 23-25, and 35-37 weeks gestation) and postpartum (6 and 12 weeks) among women in a rural setting.\n\nResearch Activities: The efficacy of BumptUp® will be determined by measuring physical activity levels (via accelerometry and surveys) between women who use the mobile app (intervention) and women who use only an educational brochure (attention control).\n\nSpecific Aim 2: Assess the efficacy of the mHealth intervention on important obstetric outcomes including maternal weight status, dietary intake, glucose tolerance, blood pressure, and mental health.\n\nResearch Activities: Maternal weight status, glucose tolerance, and blood pressure values will be obtained from patient charts. Dietary intake will be assessed via the National Cancer Institute Multifactor Screener. Maternal mental health status will be measured via The Edinberg Postpartum Depression Questionnaire, Center for Epidemiological Studies Depression Scale, and the State-Trait Anxiety Inventory.",[318,29],[394,395,396,71,397],"exercise","mHealth","pregnancy","rural","2026-02-24",{"date":400,"type":43},"2026-02-27",{"date":402,"type":43},"2023-08-01",{"date":404,"type":21},"2026-06-30",{"name":406,"class":50},"Western Kentucky University",{"id":408,"slug":409,"hasResults":12,"nctId":410,"briefTitle":411,"officialTitle":412,"acronym":413,"eligibilityCriteria":414,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":415,"targetDuration":4,"studyType":22,"phases":417,"briefSummary":419,"conditions":420,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":422,"lastUpdatePostDateStruct":423,"startDateStruct":425,"completionDateStruct":427,"leadSponsor":429,"locationsCount":51},"100603722","phase-3-short-term-low-dose-low-molecular-weight-heparin-to-prevent-postpartum-thrombosis-100603722","NCT07140211","Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum Thrombosis","Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum Thrombosis: a Pragmatic, Multi-center, Open-label Randomized Controlled Study","SHINE","Inclusion Criteria: postpartum women after delivery AND ≥1 major risk factor \u002F ≥2 minor risk factors:\n\n* Major risk factors: Emergency cesarean section ; Pre-pregnancy BMI ≥35kg\u002Fm2 ; Known low-risk thrombophilia (heterozygous factor V Leiden; heterozygous G20210 prothrombin mutation) ; Pre-eclampsia ; Pre-term delivery ; Peripartum systemic infection ; Intra-uterine growth restriction ; Pregnancy loss\n* Minor risk factors: Age ≥35 years ; Pre-pregnancy BMI 30.0-34.9kg\u002Fm2 ; Current smoking ; Elective cesarean section ; Postpartum hemorrhage ; Antenatal immobility\n\nExclusion Criteria:\n\n* ≥2 doses of postpartum LMWH\n* Any indication for therapeutic anticoagulation\n* A high-risk of postpartum VTE\n* An increased bleeding risk\n* A contra-indication to heparin",{"count":416,"type":21},9200,[418],"PHASE3","The goal of this clinical trial is to evaluate the risk-benefit of a short-term treatment with a low-dose low-molecular-weight heparin (LMWH), in the postpartum period (after delivery). The main questions it aims to answer are:\n\n* compared to no treatment, does short-term postpartum LMWH modify the risk of venous thromboembolism within 90 days of delivery?\n* compared to no treatment, does short-term postpartum LMWH modify the risks of bleeding and wound complications? Participants will take low-dose LMWH for 7-10 days or no treatment, and will be followed for 90 days post-delivery.",[421,29],"Venous Thromboembolism (VTE)","2026-02-12",{"date":424,"type":43},"2026-02-17",{"date":426,"type":43},"2025-10-15",{"date":428,"type":21},"2030-08",{"name":430,"class":50},"Marc Blondon",{"id":432,"slug":433,"hasResults":12,"nctId":434,"briefTitle":435,"officialTitle":436,"acronym":437,"eligibilityCriteria":438,"healthyVolunteers":12,"sex":337,"minAge":18,"maxAge":4,"enrollmentInfo":439,"targetDuration":4,"studyType":22,"phases":441,"briefSummary":442,"conditions":443,"keywords":444,"overallStatus":224,"whyStopped":4,"lastUpdateSubmitDate":449,"lastUpdatePostDateStruct":450,"startDateStruct":452,"completionDateStruct":454,"leadSponsor":456,"locationsCount":104},"100619425","supporting-the-transition-to-parenthood-through-online-sex-and-relationship-knowledge-100619425","NCT07344454","Supporting the Transition to Parenthood Through Online Sex and Relationship Knowledge","STORK (Supporting the Transition to Parenthood Through Online Sex and Relationship Knowledge) Randomized Controlled Trial","STORK","Inclusion Criteria:\n\n* married or cohabitating romantic relationship of at least 12 months\n* one member of the couple must be currently pregnant (13-27 weeks gestation) with their first baby together (If the couple has a history of miscarriage or stillbirth, previously gave a baby up for adoption, or have other children who do not live with them, they are still eligible to participate.)\n* low-risk pregnancy\n* live in Canada, the United States, Australia, New Zealand, the Republic of Ireland, or the United Kingdom\n* able to read and understand English\n* have access to a personal e-mail account\n\nExclusion Criteria:\n\n* severe relational distress or conflict as determined by baseline measures\n* one or both partners of a couple do not complete the baseline survey - this includes cases where one or both partners do not pass at least 3\u002F5 attention checks in the baseline survey\n* instructed to avoid sexual activity from a healthcare professional",{"count":440,"type":21},268,[24],"Becoming parents exerts powerful and long-lasting effects on couples' well-being and quality of life. The transition to parenthood (TtP; pregnancy to 12-months postpartum) poses significant challenges as couples balance the task of caring for a newborn while maintaining their romantic relationship. One crucial way that couples sustain their connection is through their sexuality. Most new parents experience significant disruptions to their sexual well-being (i.e., sexual satisfaction, desire, distress), with sexual concerns such as reduced sexual frequency and lack of time and energy for sex being nearly ubiquitous. Simultaneously, most new parents lack easily accessible, reliable information on the common sexual changes associated with the TtP and there is a lack of evidence-based research aimed at helping couples navigate changes to their sexual well-being across this life transition. The investigators have identified risk (e.g., stress) and protective (e.g., intimacy) factors for couples' sexual well-being across the TtP that can be targeted in a prevention program, though no such programs exist.\n\nThe goal of this two-centre randomized controlled trial is to evaluate the efficacy of STORK (Supporting the Transition to Parenthood through Online Sex and Relationship Knowledge), a novel couple-based online program to support new parents' sexual well-being. This program comprises psychoeducation about common sexual changes as well as skills that couples can develop together to manage these changes and constitutes the first evidence-based program for new parent couples' sexual well-being. The investigators expect that, compared to a waitlist control group, couples who complete STORK will have better sexual, relational, and psychological adjustment across the transition to parenthood (from 13 to 27-weeks gestation to 12-months postpartum). Given that up to 78% of new parents report receiving little-to-no information about what to expect regarding changes to their postpartum sexual relationship, this study addresses the need for accessible, couple-based supports for this commonly challenging transition. By strengthening couples' sexual relationships, the results of this research have the potential to promote the quality of new parents' relationships, strengthening the overall well-being of their families during this critical life stage.",[30,29],[445,446,447,448],"Transition to parenthood","sexual well-being","couples","parents","2026-01-15",{"date":451,"type":43},"2026-01-16",{"date":453,"type":21},"2026-01",{"date":455,"type":21},"2029-03",{"name":457,"class":50},"Dalhousie University",{"id":459,"slug":460,"hasResults":12,"nctId":461,"briefTitle":462,"officialTitle":462,"acronym":463,"eligibilityCriteria":464,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":465,"targetDuration":4,"studyType":244,"phases":4,"briefSummary":466,"conditions":467,"keywords":469,"overallStatus":224,"whyStopped":4,"lastUpdateSubmitDate":472,"lastUpdatePostDateStruct":473,"startDateStruct":475,"completionDateStruct":476,"leadSponsor":478,"locationsCount":480},"100620389","stelo-real-time-continuous-glucose-monitor-use-postpartum-for-lifelong-optimal-wellness-100620389","NCT07356986","Stelo Real-time Continuous Glucose Monitor Use Postpartum for Lifelong Optimal Wellness","STELO-GLOW","Inclusion Criteria:\n\n* Gestational Diabetes Mellitus (GDM) diagnosis by 1- or 2-step Oral Glucose Tolerance Test (OGTT) during pregnancy or \\>= 200 mg following any glucose challenge (50g, 75g, 100g)\n* Has a smart phone compatible to support Dexcom Stelo app\n* Able to read, write, and understand English\n* Meet Stelo Glucose Biosensor Indications for Use (IFU) per approved commercial labeling\n* Willing to follow all study procedures\n\nExclusion Criteria:\n\n* Greater than 6 weeks and 6 days postpartum at enrollment\n* Preexisting Type 1 Diabetes (T1D) or Type 2 Diabetes (T2D)\n* End-stage renal failure (on dialysis)\n* Heart failure\n* Other uncontrolled high-risk condition as determined exclusionary by site investigators\n* Extensive skin changes\u002Fdiseases that preclude wearing the required system on normal skin (e.g. extensive psoriasis, recent burns or severe sunburn, extensive eczema, extensive scarring, extensive tattoos, dermatitis herpetiformis) at the proposed wear sites\n* Known severe allergy to medical-grade adhesives\n* Any condition that, in the opinion of the investigator, would interfere with their participation in the trial\n* Obesity surgery\n* Insulin use prior to discharge home from the delivery admission\n* Current participation in another postpartum Continuous Glucose Monitoring (CGM) or lifestyle intervention trial",{"count":160,"type":21},"The purpose of this prospective observational study is to gather exploratory and practical use data of the Dexcom Stelo Glucose Biosensing System (Stelo), an over-the-counter (OTC) real-time Continuous Glucose Monitoring (CGM) system among patients with Gestational Diabetes Mellitus (GDM) in their most recent pregnancy.",[468,29],"Gestational Diabetes",[470,471],"Continuous Glucose Monitoring","Postpartum Glucose Management","2026-01-12",{"date":474,"type":43},"2026-01-21",{"date":453,"type":21},{"date":477,"type":21},"2027-12",{"name":479,"class":50},"Oregon Health and Science University",3,{"id":482,"slug":483,"hasResults":12,"nctId":484,"briefTitle":485,"officialTitle":485,"acronym":4,"eligibilityCriteria":486,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":487,"targetDuration":4,"studyType":22,"phases":489,"briefSummary":490,"conditions":491,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":472,"lastUpdatePostDateStruct":493,"startDateStruct":495,"completionDateStruct":497,"leadSponsor":499,"locationsCount":51},"100608684","hope-bp-20-evaluating-the-optimal-duration-of-postpartum-remote-blood-pressure-monitoring-100608684","NCT07204756","HOPE-BP 2.0: Evaluating the Optimal Duration of Postpartum Remote Blood Pressure Monitoring","Inclusion Criteria:\n\n* 18 years or older\n* Discharged after delivery at University of Minnesota Medical Center\n* Enrolled into the HOPE-BP Program\n\nExclusion Criteria:\n\n* Ongoing antihypertensive medication use at 2 weeks (time of randomization)\n* Have a medical comorbidity that would not be clinically appropriate to randomize\n* Patients opted out of clinical research",{"count":488,"type":21},400,[24],"Postpartum remote blood pressure monitoring programs for patients with hypertensive disorders of pregnancy (HDP) are becoming part of standard postpartum management. Existing programs range in duration from 2 to 6 weeks but there has not been any evaluation as to what program duration is optimal. The primary objective of this study is to evaluate the impact of program duration on clinical outcomes for patients participating in a single institution's postpartum remote blood pressure monitoring program for patients with HDP.",[29,27,492],"Hypertensive Disorder of Pregnancy",{"date":494,"type":43},"2026-01-14",{"date":496,"type":43},"2026-01-07",{"date":498,"type":21},"2028-01-31",{"name":500,"class":50},"University of Minnesota",{"id":502,"slug":503,"hasResults":12,"nctId":504,"briefTitle":505,"officialTitle":506,"acronym":507,"eligibilityCriteria":508,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":509,"enrollmentInfo":510,"targetDuration":4,"studyType":244,"phases":4,"briefSummary":512,"conditions":513,"keywords":518,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":525,"lastUpdatePostDateStruct":526,"startDateStruct":528,"completionDateStruct":530,"leadSponsor":532,"locationsCount":51},"100613917","usability-study-of-gestational-and-postpartum-weight-management-program-100613917","NCT07272824","Usability Study of Gestational and Postpartum Weight Management Program","Usability Study of Gestational and 6 Months Postpartum Weight Management Program - Hope D","Hope-D_Use","Inclusion Criteria:\n\n* General pregnant women with prepregnancy BMI at least 30 kg\u002Fm2\n* Competence in using the digital care pathway and electronic maternity card\n\nExclusion Criteria:\n\n\\- Significant difficulty in cooperating (e.g. inadequate Finnish language skills)","50 Years",{"count":511,"type":21},30,"The principal aim of this study is to evaluate the usability of the Hope-D gestational and 6 months postpartum weight management program. We will evaluate the usability, functionality, and acceptability of the developed Hope-D weight management program that includes digital pathway for weight management, general or individual weight management plan and individual or group coaching for weight management from pregnancy to 6 months postpartum.",[30,29,514,515,516,517],"Obese Pregnant Women","Weight Management","Digital Intervention","Usability",[519,520,521,522,523,524],"Hope-D","digital pathway","Gestational weight management","Postpartum weight management","gestational weight management plan","coaching","2025-12-16",{"date":527,"type":43},"2025-12-23",{"date":529,"type":43},"2025-12-09",{"date":531,"type":21},"2026-01-31",{"name":533,"class":209},"Turku University Hospital",{"id":535,"slug":536,"hasResults":12,"nctId":537,"briefTitle":538,"officialTitle":539,"acronym":4,"eligibilityCriteria":540,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":61,"enrollmentInfo":541,"targetDuration":4,"studyType":22,"phases":542,"briefSummary":543,"conditions":544,"keywords":545,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":549,"lastUpdatePostDateStruct":550,"startDateStruct":552,"completionDateStruct":554,"leadSponsor":556,"locationsCount":51},"100615623","digital-maternal-support-tool-implementation-100615623","NCT07295015","Digital Maternal Support Tool Implementation","Digital Maternal Support Tool Implementation: Research to Inform a Statewide Postpartum App Implementation Strategy","Inclusion Criteria:\n\n* Recently delivered one or two live births at hospital recruitment site\n* 18-45 years of age\n* Can participate in English\n* Has smartphone access for at least two months (study duration)\n\nExclusion Criteria:\n\n* Did NOT recently deliver one or two live births at hospital recruitment site\n* \\\u003C18 or \\>45 years of age\n* Cannot participate in English\n* Does not have smartphone for at least two months (study duration)",{"count":135,"type":21},[24],"The goal of this trial is to learn if a smartphone app designed to provide postpartum support is acceptable to new mothers in Pennsylvania. The main questions it aims to answer are:\n\n* How easy is the app is to use?\n* Does the app meet the needs of new parents?\n* Is using the app associated with better understanding of critical postpartum symptoms?\n* Is using the app associated with endorsement of positive parenting statements?\n\nParticipants will:\n\n* Use a postpartum support app on their smartphones for 8 weeks\n* Answer survey questions about their experience",[29],[71,546,547,548],"parenting","smartphone","mobile applications","2025-12-15",{"date":551,"type":43},"2025-12-19",{"date":553,"type":43},"2025-12-01",{"date":555,"type":21},"2026-12",{"name":557,"class":50},"University of Pittsburgh",{"id":559,"slug":560,"hasResults":12,"nctId":561,"briefTitle":562,"officialTitle":563,"acronym":564,"eligibilityCriteria":565,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":566,"targetDuration":4,"studyType":22,"phases":568,"briefSummary":569,"conditions":570,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":571,"lastUpdatePostDateStruct":572,"startDateStruct":574,"completionDateStruct":576,"leadSponsor":578,"locationsCount":104},"100598064","the-pregnancy-and-postpartum-mental-health-optimization-virtual-intervention-network-100598064","NCT07066631","The Pregnancy and Postpartum Mental Health Optimization Virtual Intervention Network","The Pregnancy and Postpartum Mental Health Optimization Virtual Intervention Network (MOVIN): Randomized Controlled Trial","MOVIN","Inclusion Criteria:\n\n1. Adult (age 18 years or older)\n2. Pregnant or postpartum and living with their infant 0-6 months old. This includes all individuals who identify as women, as well as those of female sex who do not identify as women (e.g., non-binary, trans) who are the primary parent for their infant. This includes via natural birth, adoption, or surrogacy.\n3. EPDS score \\>10 at eligibility screening.\n\nExclusion Criteria:\n\n1. Active alcohol or substance use disorder, mania or psychotic disorder (as these conditions are better managed in direct specialty care).\n2. Active suicide plan or intent (as emergent hospital-based care is likely required),\n3. Plan to move out of Ontario during the study.\n4. Unable to complete relevant study procedures and measures online. For the few participants without access to devices\u002Fhome internet, we will budget for tablets\u002Fdata plans.\n5. Unable to complete study activities in English. Note that Google translate is available for the intervention platform and language lines are available for participants so that they can be served in their language of choice, however we are unable to provide translations of all study assessment and questionnaire materials that participants will need to complete during the study.\n6. No primary care clinician (required for collaborative mental health care delivery model).\n7. Currently enrolled in a collaborative mental health care model.",{"count":567,"type":21},570,[24],"Depression, anxiety, and related disorders such as post-traumatic stress and obsessive compulsive disorder affect about 20% of pregnant and postpartum people. When not treated properly, these issues negatively impact not only affected people, but also their children's health and development. Only 1 in 5 receive adequate treatment, so identifying new system-wide approaches to reliably deliver recommended care to perinatal mental health patients all is a crucial health care priority. The Pregnancy and Postpartum Mental health Optimization Virtual Intervention Network (MOVIN) is a scalable perinatal mental health platform building on the evidence-based Collaborative care delivery model. MOVIN's online platform allows patients to connect with a care coordinator to co-develop personalized treatment recommendations, in collaboration with their primary care clinician and a perinatal psychiatrist when needed; progress is tracked to re-evaluate.",[32,29,31,30],"2025-11-18",{"date":573,"type":43},"2025-11-24",{"date":575,"type":43},"2025-10-29",{"date":577,"type":21},"2029-03-31",{"name":579,"class":50},"Women's College Hospital",{"id":581,"slug":582,"hasResults":12,"nctId":583,"briefTitle":584,"officialTitle":585,"acronym":586,"eligibilityCriteria":587,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":588,"targetDuration":4,"studyType":22,"phases":589,"briefSummary":590,"conditions":591,"keywords":599,"overallStatus":224,"whyStopped":4,"lastUpdateSubmitDate":611,"lastUpdatePostDateStruct":612,"startDateStruct":614,"completionDateStruct":616,"leadSponsor":618,"locationsCount":51},"100610142","postpartum-education-via-artificial-intelligence-for-recovery-and-loneliness-a-randomized-controlled-trial-100610142","NCT07223736","Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial","Postpartum Education Via Artificial Intelligence for Recovery and Loneliness (PEARL): A Randomized Controlled Trial","PEARL","Inclusion Criteria:\n\n1. Has the capacity to provide informed consent\n2. Stated willingness to comply with all study procedures and availability for the duration of the study\n3. Postpartum persons, aged \\>18 years old\n4. Primiparous\n5. Vaginal or cesarean delivery\n6. English Speaking\n7. Internet access and proficiency of internet access\n8. Access to a smartphone\n9. Postpartum 2-6 weeks\n\nExclusion Criteria:\n\n1. Multiparous\n2. Major neonatal anomaly\n3. Delivery \\\u003C 34 weeks gestational age\n4. Intrauterine fetal demise (IUFD)\n5. Enrollment in any interfering studies\n6. Unanticipated NICU admission\n7. Discharge home without live baby\n8. Surrogates\u002Fgestational carrier\n9. Birthing individuals with baby placed for adoption\n10. Currently pregnant\n11. Psychiatric history requiring psychiatric hospitalization prior to delivery\n12. Other psychiatric conditions needing immediate attention and intervention as determined by study team and\u002For treatment team",{"count":243,"type":21},[24],"The goal of this clinical trial is to learn whether a postpartum chatbot powered by generative artificial intelligence (genAI) can help new mothers get better pelvic floor health information and feel less lonely after childbirth.\n\nThe main questions this study aims to answer are:\n\n* Does using the chatbot improve postpartum pelvic floor health knowledge?\n* Does using the chatbot help reduce feelings of loneliness during the postpartum period?\n* Does using the chatbot impact pelvic floor symptoms?\n\nResearchers will compare standard postpartum care to standard care plus the chatbot.\n\nParticipants will:\n\nBe assigned by chance (like flipping a coin) to standard postpartum care with or without access to the chatbot.\n\nIf in the chatbot group, participants will receive education and support via the chatbot over a 4-week period.\n\nBoth groups will complete questionnaires to measure their pelvic floor knowledge, pelvic floor symptoms, feelings of loneliness, depression, infant bonding, perceived social support, adverse childhood experiences, and peri-traumatic distress.\n\nThe chatbot was created by urogynecology experts in collaboration with UC San Diego computer science and biomedical informatics researchers. The chatbot is designed to give new mothers personalized, evidence-based information and support in real time.",[592,593,29,594,32,595,596,597,598],"Pelvic Floor Disorder","Loneliness","Mental Health","Peritraumatic Distress","Women","Artificial Intelligence (AI)","Chatbot",[600,71,601,602,603,604,605,606,607,608,609,610],"loneliness","pelvic floor disorder","mental health","depression","peritraumatic distress","artificial intelligence","AI","chatbot","LLM","women","large language model","2025-10-31",{"date":613,"type":43},"2025-11-03",{"date":615,"type":21},"2025-11-10",{"date":617,"type":21},"2026-11-01",{"name":619,"class":50},"University of California, San Diego",{"id":621,"slug":622,"hasResults":12,"nctId":623,"briefTitle":624,"officialTitle":625,"acronym":4,"eligibilityCriteria":626,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":627,"targetDuration":4,"studyType":244,"phases":4,"briefSummary":629,"conditions":630,"keywords":634,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":642,"lastUpdatePostDateStruct":643,"startDateStruct":645,"completionDateStruct":647,"leadSponsor":649,"locationsCount":51},"100609148","the-effect-of-crowning-time-on-levator-ani-muscle-avulsion-100609148","NCT07210788","The Effect of Crowning Time on Levator Ani Muscle Avulsion","Evaluation of Crowning Time on the Incidence of Levator Ani Muscle Avulsion","Inclusion Criteria:\n\nPrimiparous women GxT1 At term: ≥ 37+0 weeks of gestation (included) Spontaneous vaginal delivery (SVD) Cephalic presentation History of miscarriage before 20 weeks or with a fetal weight \\\u003C 350g\n\nExclusion Criteria:\n\nContraindications to vaginal delivery Assisted vaginal delivery Age under 18 years Shoulder dystocia Extensive pelvic reconstructive surgery (e.g., bladder exstrophy repair) Term intrauterine fetal demise Twin or multifetal pregnancy",{"count":628,"type":21},92,"Levator ani muscle is one of the main components of perineal muscles and plays a crucial role in urinary continence and pelvic organ support. An avulsion, detachment from its insertion, of this muscle can occur during vaginal birth. It is well known that this major injury can cause many symptoms such as urinary incontinence and pelvic organ prolapses. Some risk factors of this important injury have been identified in the literature, such as the use of forceps. However, to date, no study has evaluated the impact of the crowning of the fetal head during labor on perineal muscles, specifically the levator ani muscle avulsion. Hence, the objectives of this study are to evaluate the association i) the time of the crowning of the fetal head during labor and levator ani muscle avulsion, ii) the time of the crowning of the fetal head and urogynecological symptoms, and iii) use of episiotomy and levator ani muscle avulsion. Postpartum primiparous women will undergo a 4D transperineal ultrasound to evaluate their pelvic muscles and complete questionnaires assessing urogynecological symptoms.",[631,632,633,29],"Time of the Crowning of the Fetal Head","Levator Ani Avulsion","Labor Delivery",[635,636,637,638,639,640,641,71],"levator ani","levator ani avulsion","crowning time","crowning time of the fetal head","primiparous","singleton foetus","vertex position","2025-09-29",{"date":644,"type":43},"2025-10-07",{"date":646,"type":43},"2024-04-23",{"date":648,"type":21},"2027-02",{"name":650,"class":50},"Université de Sherbrooke",{"id":652,"slug":653,"hasResults":12,"nctId":654,"briefTitle":655,"officialTitle":656,"acronym":657,"eligibilityCriteria":658,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":509,"enrollmentInfo":659,"targetDuration":4,"studyType":22,"phases":661,"briefSummary":664,"conditions":665,"keywords":670,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":673,"lastUpdatePostDateStruct":674,"startDateStruct":676,"completionDateStruct":678,"leadSponsor":680,"locationsCount":51},"100607040","phase-1-msc-exosome-therapy-for-post-preeclampsia-endothelial-dysfunction-100607040","NCT07183384","MSC Exosome Therapy for Post-Preeclampsia Endothelial Dysfunction","The Effectiveness of Mesenchymal Stem Cell-Derived Exosome Therapy in Improving Endothelial Dysfunction in Postpartum Mothers With a History of Preeclampsia","EXITPE","Inclusion Criteria:\n\n* Postpartum\n* Confirmed diagnosis of preeclampsia in the last pregnancy\n* Postpartum period of first week and second week\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* History of chronic hypertension prior to pregnancy\n* Major cardiovascular disease history\n* Active systemic infection\n* Endothelial Injury history\n* Active smoking status including vape, alcohol, drug addiction.",{"count":660,"type":21},80,[662,663],"PHASE1","PHASE2","\\---\n\nWhy Is This Study Being Done?\n\nWomen who have preeclampsia during pregnancy face a much higher risk of heart disease later in life. Preeclampsia is a serious pregnancy condition that causes high blood pressure and damages blood vessels. Even after the baby is born, the blood vessels do not fully heal on their own, which can lead to heart problems\u002Fcardiovascular years later.\n\nThis study tests whether a new treatment called exosomes can help repair damaged blood vessels in women who had preeclampsia. Exosomes are tiny particles that come from stem cells and contain healing substances that may help blood vessels work better.\n\n\\---\n\nWhat Will Happen in This Study?\n\nThis study will include 80 women who recently gave birth and had preeclampsia during their pregnancy. Half of the women will receive the exosome treatment through an IV, and half will receive a placebo (a substance with no active treatment).\n\n\\---\n\nWhat Will Participants Need to Do?\n\nParticipants will:\n\n* Have blood tests and other health checks\n* Receive one treatment through an IV\n* Return for follow-up visits at 1 week after treatment\n* Have tests to check how well their blood vessels are working\n\nWho Can Join This Study?\n\nWomen who:\n\n* Recently gave birth (within 1-2 weeks)\n* Had preeclampsia during their last pregnancy\n* Are healthy enough to participate\n* Can give permission to join the study\n\nWhat Are the Possible Benefits and Risks?\n\nThe treatment may help repair blood vessel damage and reduce the risk of future heart disease. The exosome treatment appears to be safe based on other studies, but like any medical treatment, there may be side effects.\n\n\\---\n\nHow Long Will the Study Last?\n\nThe main treatment happens during one visit, with follow-up visits for 1 week to check on participants' health and see if the treatment is working.\n\nThis research may lead to new ways to protect women's heart health after pregnancy complications.",[666,29,667,668,669],"Preeclampsia","Endothelial Injury","Exosome Multiomics","Cell Therapy",[666,29,671,672,669],"Stem Cell","Exosome","2025-09-12",{"date":675,"type":43},"2025-09-19",{"date":677,"type":43},"2024-07-01",{"date":679,"type":21},"2026-09-01",{"name":681,"class":50},"Universitas Padjadjaran",{"id":683,"slug":684,"hasResults":12,"nctId":685,"briefTitle":686,"officialTitle":686,"acronym":4,"eligibilityCriteria":687,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":688,"targetDuration":4,"studyType":22,"phases":690,"briefSummary":691,"conditions":692,"keywords":693,"overallStatus":224,"whyStopped":4,"lastUpdateSubmitDate":701,"lastUpdatePostDateStruct":702,"startDateStruct":704,"completionDateStruct":706,"leadSponsor":707,"locationsCount":4},"100583818","effectiveness-of-a-smartphone-app-primi-to-promote-healthy-diet-and-physical-activity-after-pregnancy-in-migrant-women-100583818","NCT06881277","Effectiveness of a Smartphone App (PRIMI) to Promote Healthy Diet and Physical Activity After Pregnancy in Migrant Women","Inclusion Criteria:\n\n* First-generation migrant women\n* Given birth ≤ 6 months ago\n* Age ≥ 18 years\n* Able to receive health-related information in Arabic, Somali, English, or Swedish\n\nExclusion Criteria:\n\n* Swedish-born women\n* Age \\\u003C 18 years\n* Given birth \\> 6 months ago",{"count":689,"type":21},200,[24],"The PRIMI trial (Promoting Reproductive health In MIgrant women) is a randomized controlled trial evaluating the effectiveness of a smartphone app designed to promote a healthy diet, physical activity, and health literacy among first-generation migrant women after pregnancy. The study will recruit 200 women within six months after pregnancy and randomize them into an intervention group, receiving access to the PRIMI app for six months, or a wait-list control group. The primary outcomes are diet quality and moderate-to-vigorous physical activity, while secondary outcomes include health literacy, body mass index, self-efficacy, and self-rated health. The intervention is expected to provide accessible and culturally tailored support to improve postpartum health behaviors.",[29],[395,694,695,71,396,696,697,698,699,700],"app","randomized controlled trial","migration","migrant health","diet","physical activity","health literacy","2025-09-10",{"date":703,"type":43},"2025-09-16",{"date":705,"type":21},"2025-09-15",{"date":378,"type":21},{"name":708,"class":209},"Linkoeping University"]