[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pre-exposure-prophylaxis-prep\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pre-exposure-prophylaxis-prep":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100566913","peer-led-community-based-prep-delivery-among-youth-in-brazil-100566913",false,"NCT06661356","Peer-led Community-based PrEP Delivery Among Youth in Brazil","Determining the Impact of Peer-led Community-based PrEP Delivery Among Youth in Brazil: A Randomized Controlled Trial","COMPrEP","Eligibility Criteria:\n\n* Aged 15-24 years\n* Candidate for HIV prevention\n* Sexually active\n* Not currently using PrEP\n* Willing to discuss oral PrEP\n* Agree to be randomized to either intervention or standard care arm\n\nExclusion Criteria:\n\n* HIV positive test result\n* Not currently sexually active\n* Currently using PrEP",true,"ALL","15 Years","24 Years",{"count":22,"type":23},1400,"ESTIMATED","INTERVENTIONAL",[26],"NA","The goal of this project is to conduct a series of studies to refine, test, and understand experiences with a peer-led community-based intervention in which youth will be integrated into health care teams and trained to deliver HIV pre-exposure prophylaxis (PrEP) to their peers. The study team will conduct a randomized trial to determine if peer delivery of PrEP to youth aged 15-24 in Brazil will increase PrEP uptake, persistence, and adherence compared to standard PrEP care provided in health facilities.",[29,30],"Pre-Exposure Prophylaxis (PrEP)","HIV",[32,33,30,34,35],"PrEP","Pre-Exposure Prophylaxis","Peer lay workers","Youth","NOT_YET_RECRUITING","2026-03-03",{"date":39,"type":40},"2026-03-05","ACTUAL",{"date":42,"type":23},"2026-10",{"date":44,"type":23},"2029-08",{"name":46,"class":47},"University of Alabama at Birmingham","OTHER",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":17,"sex":18,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":24,"phases":58,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":83},"100570663","filling-gaps-in-the-hiv-pre-exposure-prophylaxis-cascade-through-counseling-100570663","NCT06710171","Filling Gaps in the HIV Pre-exposure Prophylaxis Cascade Through Counseling","Filling Gaps in the PrEP Cascade: User-centered Counseling About HIV Pre-exposure Prophylaxis and Linkage to Care for Gay, Bisexual and Other Men Who Have Sex with Men","Eligible participants at the provider level ('provider-participants') will be nurses, nurse practitioners, counselors and physicians working at sexual health clinics, public health clinics and primary care practices, with or without experience giving PrEP counseling.\n\n1A. Inclusion criteria for provider-participants:\n\n* For practicing health-care professionals, hold a valid license to practice in Ontario (this includes resident physicians)\n* Anticipate encountering a minimum of five PrEP-eligible GBM and TGNC eligible for PrEP in the three months after enrolling in the study\n\n  1B. Exclusion criteria for provider-participants\n* Anticipate to stop working at their current practice site before the end of the study\n\n  2A. Inclusion criteria for user-participants\n* Be \\> 19 years of age\n* Self-identify as a gender different from cisgender woman\n* Be presenting to their provider for sexual health\u002FHIV testing or any other services\n* Not having used PrEP in the three months prior to enrollment\n* Having clinical indication for PrEP as per the Canadian PrEP guideline (i.e.: -\n* Report having condomless anal sex with a man in the preceding 6 months plus any of the following: syphilis in the past year, rectal gonorrhea, LGV or chlamydia in the past year, use of PEP at least twice, ongoing sexual relationship with a person living with HIV with detectable viral load, or HIRI-MSM score \\> 11 if available).\n\n  2B. Exclusion criteria for user-participants\n* User-participants who have already received an invitation to participate in the study and declined will not be included since that means they would have received the intervention or the control in the past.\n* Users who request getting on PrEP due to high self-perceived risk despite not meeting the clinical criteria specified above, will not be included.\n* Not being able to communicate in English","19 Years",{"count":57,"type":23},200,[26],"This study s objective is to test the acceptability and feasibility of a guide to facilitate counseling about HIV prevention, focusing on HIV pre-exposure prophylaxis (PrEP). PrEP is a medication taken by HIV-negative persons to avoid an HIV infection.\n\nHealthcare providers (including but not limited to physicians and nurses) who see gay, bisexual and other men who have sex with men (GBM) will be randomly assigned to completing a short online training versus continuing their usual activities.\n\nThe online training consists of modules containing brief information about PrEP, and about how to address concerns and difficulties that GBM face to get PrEP and to take care of their sexual health.\n\nThe investigators will ask healthcare providers to answer questionnaires before and after the research activities take place, and a member of the research team will interview some of them at the end.\n\nEvery time a healthcare provider has a counseling session with a GBM, they will facilitate putting a research coordinator in touch with the person receiving the counseling. Those GBM will also be asked to fill out questionnaires.\n\nThese activities will take place in the province of Ontario, Canada.",[29,61,62],"Counseling","Sexual and Gender Minorities",[64,65,66,67,68,69,70,71,72,73],"gay","men who have sex with men","bisexual","HIV PrEP","Pre-exposure prophylaxis","primary care","counseling","pilot trial","HIV prevention","sexual health","2024-11-25",{"date":76,"type":40},"2024-11-29",{"date":78,"type":23},"2025-01",{"date":80,"type":23},"2025-03",{"name":82,"class":47},"Unity Health Toronto",1]