[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pregnancy-complicated-by-cardiovascular-disorders-as-postpartum-condition-delivered-during-previous-episode\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pregnancy-complicated-by-cardiovascular-disorders-as-postpartum-condition-delivered-during-previous-episode":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100614121","pregnancy-and-fibrin-clot-properties-100614121",false,"NCT07275476","Pregnancy and Fibrin Clot Properties","Fibrin Clot Properties and Thrombin Generation in Pregnancy Women With and Without Obstetric Complications.","Inclusion Criteria:\n\nI. age 18-40 years; II. natural conception (without assisted reproductive techniques).\n\nExclusion Criteria:\n\nI. use of hormonal therapy (i.e., oral contraceptives, progestogens) within 3 months before or during pregnancy; II. use of anticoagulants oral\u002Fsubcutaneous within 3 months before or during pregnancy; III. increased risk factors of VTE (i.e., obesity - body mass index \\>30 kg\u002Fm2; smoking) or history of VTE; IV. Concomitant diseases, i.e: severe hypertension, diabetes mellitus, autoimmune diseases (i.e., systemic lupus erythematosus, antiphospholipid syndrome); V. congenital or acquired thrombophilia (i.e., mutation factor V Leiden, prothrombin mutation).",true,"FEMALE","18 Years","40 Years",{"count":21,"type":22},100,"ESTIMATED","OBSERVATIONAL","1. The structure of fibrin clot and thrombin generation may vary between trimesters of pregnancy.\n2. Unfavorably altered fibrin clot properties along with enhanced thrombin generation may lead to the development of complications during pregnancy such as TE and hypertensive disorders.\n3. The application of machine learning techniques may help to identify previously undetected phenotypes with increased risk of TE and hypertensive disorders during pregnancy.",[26,27,28],"Fibrin Blood Clot","Pregnancy","Pregnancy Complicated by Cardiovascular Disorders as Postpartum Condition, Delivered During Previous Episode",[30,31,32],"fibrinolysis","fibrin clot","thrombin generation","RECRUITING","2025-11-28",{"date":36,"type":37},"2025-12-10","ACTUAL",{"date":34,"type":37},{"date":40,"type":22},"2027-12",{"name":42,"class":43},"Jagiellonian University","OTHER"]