[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pregnancy-outcome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pregnancy-outcome":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,45,80,112,145,171,196,228],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100512089","real-time-continuous-glucose-monitoring-system-in-t2dm-with-pregnacy-100512089",false,"NCT05947916","Real Time Continuous Glucose Monitoring System in T2DM With Pregnacy","Effect of Real Time Continuous Glucose Monitoring System on Management of Women With Type 2 Diabetes Mellitus During Pregnancy in a Multidisciplinary Comprehensive System","Inclusion Criteria:\n\n* A clear history of type 2 diabetes, or a history of type 2 diabetes diagnosed in early pregnancy\n* Singleton gestation at 4-26 weeks, with substandard glycemic control (i.e., fasting glucose \\> 5.3 mmol\u002FL, and or 1 hour postprandial glucose \\> 7.8 mmol\u002FL, and or 2 hours postprandial glucose \\> 6.7 mmol\u002FL) after lifestyle intervention ± basal insulin therapy, as assessed by the endocrinology department. Patients who need insulin regimen with basal plus meal or insulin pump regimen.\n* Patients are willing and committed to establish and follow up in the obstetrics and gynecology departments of Peking University Third Hospital, Haidian District Hospital and Yanqing District Hospital during pregnancy, and are willing to provide information on obstetric examination and perinatal medical records if they are transferred to the hospital for special reasons for follow-up or delivery.\n* Voluntarily participate in the study, examine and follow up according to this project and sign informed consent.\n* Able to pass the screening period Adherence evaluation\n\nExclusion Criteria:\n\n* Patients with type 1 diabetes, specific type of diabetes or gestational diabetes\n* Pregnancy with severe comorbidities or diabetic complications for which obstetrics does not recommend continuation of pregnancy, including but not limited to the following: proliferative retinopathy, chronic kidney disease (eGFR less than 60 mL\u002Fmin\u002F1.73± massive proteinuria), known coronary and cerebrovascular disease, autoimmune system disease and receiving exogenous glucocorticoids or immunosuppressive therapy.\n* Patients who have been hospitalized for psychiatric treatment within 6 months prior to enrollment or are still on psychiatric medications.\n* Patients who have received other interventional studies.","FEMALE","18 Years","40 Years",{"count":20,"type":21},240,"ESTIMATED","INTERVENTIONAL",[24],"NA","The prevalence of type 2 diabetes mellitus (T2DM) in women of childbearing age is increasing rapidly, and low glucose compliance leads to an increased risk of adverse pregnancy outcomes for mothers and infants during pregnancy in women with T2DM. Real-time continuous glucose monitoring (CGM) is an important tool for glucose monitoring and patient education, as it can continuously record blood glucose throughout the day and provide real-time feedback on high and low blood glucose levels. This is a multicenter, open-label, randomized controlled clinical study to investigate the efficacy, safety, and maternal and infant pregnancy outcomes of using real-time CGM monitoring compared with conventional self-monitoring of blood glucose (SMBG) on the basis of multidisciplinary management in pregnant women with T2DM. One hundred and twenty pregnant women with T2DM in early pregnancy who were enrolled in intensive insulin therapy were randomly divided into the real-time CGM group and the conventional SMBG group. The real-time CGM intervention group wore real-time CGM for more than 50% of the pregnancy in addition to regular SMBG; the control group only performed regular SMBG. Both groups wore Medtronic iPro 2 for 3 days in early, mid and late pregnancy, and the time in the target range of blood glucose (TIR) was recorded in a blinded manner. Primary outcome: differences in TIR between the two groups of pregnant women in early, mid, and late pregnancy. Secondary outcomes included differences in glycated hemoglobin, hypoglycemia, insulin dose before delivery, pregnancy weight gain, and maternal and infant pregnancy outcomes.",[27,28,29,30,31],"Type2diabetes","Pregnancy Related","Continuous Glucose Monitoring","Time in Range","Pregnancy Outcome","RECRUITING","2026-06-30",{"date":35,"type":36},"2026-07-02","ACTUAL",{"date":38,"type":36},"2024-01-30",{"date":40,"type":21},"2026-12-31",{"name":42,"class":43},"Peking University Third Hospital","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100640472","bed-rest-with-a-short-cervix-on-preterm-birth-100640472","NCT07577388","Bed Rest With a Short Cervix on Preterm Birth","BEWISE - Bed Rest With a Short Cervix on Preterm Birth","BEWISE","Pregnant women with gestational age 20+0 to 33+6\n\n* Cervical length \\\u003C 25 mm in singleton pregnancies and \\\u003C 30 mm in multiple pregnancies\n* Above 18 years of age\n* Reads and understands Danish or English",{"count":54,"type":21},6000,[24],"Maternal AR has long been used to prevent PTB. However, definitions of AR vary widely, ranging from complete bed rest to partial limitation of physical activity for one or more hours daily.\n\nThe use of maternal AR to prevent preterm birth is largely based on observational evidence linking strenuous physical activity to an increased risk of preterm birth, and the assumption that reduced activity may decrease myometrial activity. However, the existing evidence on the clinical effects of AR remains limited and has not demonstrated a reduction in preterm birth or a delay in deliv-ery. In contrast, some studies suggest a potential increase in preterm birth following AR and instead significant adverse maternal and fetal effects.\n\nThe overall aim of this study is to compare gestational age at birth in women with a short cervix who are prescribed AR compared with women with a short cervix who are not prescribed AR (NAR).\n\nThe primary hypothesis is that NAR is non-inferior to AR in prolonging pregnancy in women with a short cervix.\n\nSecondary hypotheses are that, compared with AR, NAR is associated with higher level of physical activity, lower risk of maternal depression, and reduced risk of loss of maternal bone mineral density.\n\nThrough the BEWISE study, we wish to implement a change in the Danish national clinical practice regarding AR from recommending AR in risk groups (current practice) to no longer recommending AR as part as routine care (new practice). We will evaluate this change in clinical practice by prospectively collecting data from women both before and after implementation of the new recommendation. The transition from AR to NAR will be implemented sequentially in each Danish region using a randomised stepped-wedge (SW) cluster design, with each region constituting a cluster. The order in which regions transition is determined by randomisation. Each region will adopt the new recommendation at 3-month intervals, resulting in full national transition from AR to NAR within 12 months Eligible participants are pregnant women in gestational age 20+0 to 33+6 and cervical length \\\u003C 25 mm in singleton pregnancies and \\\u003C 30 mm in multiple pregnancies. Participants must be above 18 years of age and be able to read and understand Danish or English. There are no exclusion criteria.\n\nThe primary outcome is gestational age in days (continuous).",[58,59,60,61,62,63,31,64,65,66,67,68,69],"Preterm Birth","Cervical Insufficiency","Bed Rest","Pregnancy Complications","Immobilization","Depression, Postpartum","Infant, Premature","Uterine Cervical Incompetence","Premature Birth","Obstetric Labor, Premature","Physical Activity","Bone Density","NOT_YET_RECRUITING","2026-05-03",{"date":73,"type":36},"2026-05-11",{"date":75,"type":21},"2026-05-01",{"date":77,"type":21},"2029-05-01",{"name":79,"class":43},"Julie Glavind",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":16,"minAge":17,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":22,"phases":92,"briefSummary":93,"conditions":94,"keywords":97,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":44},"100370937","pregnancy-and-developmental-outcomes-after-transfer-of-reportedly-aneuploid-or-mosaic-embryos-100370937","NCT04109846","Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos","Transfer of Aneuploid or Mosaic Embryos Following Preimplantation Genetic Testing","TAME","Inclusion Criteria:\n\n* Available aneuploid or mosaic embryos\n* No other acceptable embryos available\n* Willing to travel to Stanford for treatment\n* English language fluency\n\nExclusion Criteria:\n\n* Use of international donor eggs or sperm not tested according to FDA guidelines.\n* Living outside the United States\n* Embryos with Triploidy are not eligible for transfer in this protocol",true,"55 Years",{"count":91,"type":21},300,[24],"To determine how often embryos reported to be abnormal by preimplantation genetic testing result in liveborn infants. To evaluate whether the pregnancies that result from these embryos are higher risk for complications and whether the resulting babies have higher risk for health or developmental issues in the first five years after birth.",[95,96,31],"Aneuploidy","Mosaicism",[98,99,100,101,102],"Preimplantation Genetic Testing for Aneuploidy","Preimplantation Genetic Screening","embryo transfer","mosaic","aneuploid","2026-04-21",{"date":105,"type":36},"2026-04-24",{"date":107,"type":36},"2019-04-11",{"date":109,"type":21},"2039-04-01",{"name":111,"class":43},"Stanford University",{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":88,"sex":16,"minAge":17,"maxAge":120,"enrollmentInfo":121,"targetDuration":4,"studyType":22,"phases":123,"briefSummary":124,"conditions":125,"keywords":130,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":143,"locationsCount":44},"100570320","physical-activity-fertility-and-spontaneous-abortion-in-danish-couples-trying-to-conceive-100570320","NCT06705712","Physical Activity, Fertility, and Spontaneous Abortion in Danish Couples Trying to Conceive","A Preconception Cohort Study of Physical Activity, Fertility, and Spontaneous Abortion - Including a Randomized Controlled Trial.","SF\u002FActivity","Inclusion Criteria:\n\n* Female\n* 18-49 years\n* In a relationship with a male partner\n* Trying to conceive\n\nExclusion Criteria:\n\n* Using birth control\n* Receiving fertility treatment\n* Have been trying to conceive for more than six months","49 Years",{"count":122,"type":21},530,[24],"Physical activity in both the preconception period and during pregnancy may enhance the probability of getting pregnant and reduce the risks of complications during pregnancy. Adults, including pregnant women without complications, are recommended to be physically active for at least 30 minutes per day to maintain physical and mental health. Nonetheless, many women reduce their level of exercise during early pregnancy.\n\nWith this project, we will test the effectiveness of receiving motivational counseling on physical activity (PA) among women trying to conceive and during the first trimester of the pregnancy if they conceive. We will further investigate whether PA is associated with fecundability, spontaneous abortion (SAB) and other birth outcomes, i.e., gestational diabetes, preeclampsia, and birth weight.",[126,127,128,129,31,61],"Fertility","Fecundability","Time-to-Pregnancy","Spontaneous Abortion",[131,132,133,126,134,135,127,136],"Exercise","Physical activity","Sedentary behaviour","Spontaneous abortion","Preconception care","Time to pregnancy","2025-01-24",{"date":139,"type":36},"2025-01-28",{"date":141,"type":36},"2025-01-01",{"date":40,"type":21},{"name":144,"class":43},"University of Aarhus",{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":88,"sex":16,"minAge":152,"maxAge":18,"enrollmentInfo":153,"targetDuration":4,"studyType":155,"phases":4,"briefSummary":156,"conditions":157,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":44},"100495605","non-invasive-imaging-technique-for-the-study-of-lordosis-in-pregnant-women-and-its-relationship-to-birth-outcome-100495605","NCT05733377","Non-invasive Imaging Technique for the Study of Lordosis in Pregnant Women and Its Relationship to Birth Outcome","Validation of a Non-invasive Image Technique for Studying Pregnant Women´s Lordosis. Relation Between Lordosis and Childbirth Outcome.","Inclusion Criteria:\n\n* pregnant women between 20 and 40 years old with a low-risk pregnancy\n\nExclusion Criteria:\n\n* Pregnant women under 20 years and over 40 years of age or with a significant lumbar pathology or with a very high-risk pregnancy or with IMC \\>35","20 Years",{"count":154,"type":21},122,"OBSERVATIONAL","The study consists of collecting measurement data of the rachis in pregnant women and the subsequent outcome of her delivery.\n\nThis will make it possible to validate a non-invasive imaging technique through software that can be used to study this anatomical curve proposing a new measurement method for the angle of lordosis.\n\nFinally, with the research data, the investigators will try to find a correlation between these variables (angle of lordosis and delivery outcome.",[31,158,159,160,161],"Biomechanics","Back Disorder","Diagnostic Imaging","Biomedical Technology","2024-11-06",{"date":164,"type":36},"2024-11-08",{"date":166,"type":36},"2022-07-15",{"date":168,"type":21},"2025-06-30",{"name":170,"class":43},"University of Alcala",{"id":172,"slug":173,"hasResults":11,"nctId":174,"briefTitle":175,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":88,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":22,"phases":179,"briefSummary":180,"conditions":181,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":44},"100506168","generation-r-next---optimaal-opgroeien-100506168","NCT05870878","Generation R Next - Optimaal Opgroeien","Inclusion Criteria:\n\nWomen and their parents:\n\n* Planning a pregnancy or early pregnancy up to \\\u003C 12 weeks\n* With the presence of at least one of the predetermined risk factors\n* Residential address in the municipality of Rotterdam and expected residential address in the municipality of Rotterdam at the birth of their child\n* Consent for participation\n\nExclusion Criteria:\n\nWomen and their partners:\n\n* Temporary or complete withdrawal from participation\n* Gestational age \\> 12+0 at study entry",{"count":178,"type":21},1750,[24],"The aim of this randomized controlled trial is to improve birth outcomes and long-term outcomes in mother and child by optimizing lifestyle,nutrition and stress experience in the preconception period and early pregnancy in women and men\n\nThe main research question that will be addressed is: Does an intervention focused on optimizing preconception and early pregnancy lifestyle, nutrition and stress improve the birth outcomes and long-term outcomes in mother and child?\n\nParticipants will receive an individual lifestyle consultation at the start of the study. Depending on their study arm, participants will receive an additional lifestyle program focused on health during preconception and early pregnancy, coping with stress and adherence to a healthy(er) lifestyle. The given advices are based on national guidelines.\n\nResearchers will compare the intervention group and control group to see if (adherence to) this lifestyle program improve birth outcomes and long-term outcomes in mother and child.",[182,183,184,185,31,61,186],"Pregnancy Early","Outcome, Adverse Birth","Lifestyle Factors","Preconception Care","Risk Reduction Behavior","2024-08-30",{"date":189,"type":36},"2024-09-04",{"date":191,"type":36},"2023-01-19",{"date":193,"type":21},"2030-11-08",{"name":195,"class":43},"Erasmus Medical Center",{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":202,"eligibilityCriteria":203,"healthyVolunteers":88,"sex":204,"minAge":4,"maxAge":4,"enrollmentInfo":205,"targetDuration":4,"studyType":155,"phases":4,"briefSummary":207,"conditions":208,"keywords":214,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":220,"startDateStruct":222,"completionDateStruct":224,"leadSponsor":226,"locationsCount":44},"100403176","gdm-and-its-consequences-in-mothers-and-offsprings-100403176","NCT04529889","GDM and Its Consequences in Mothers and Offsprings","Gestational Diabetes Mellitus and Its Consequences in Mothers and Offsprings","GDMCMO","Inclusion Criteria:\n\n1. Pregnant women diagnosed with gestational diabetes mellitus\n2. Pregnant women intended to eventually deliver in Guangzhou Women and Children's Medical Center\n3. Permanent residents or families intended to remain in Guangzhou with their child for no less than 3 years\n\nExclusion Criteria:\n\n1. Women with pre-gestational diabetes mellitus\n2. Women with chronic hypertension or kidney disease","ALL",{"count":206,"type":21},7000,"Gestational diabetes mellitus (GDM) is one of the most common disorders which occured during pregnancy. GDM is not only associated with short-term maternal and fetal adverse outcomes, but also related to a wide range of long-term consequences for both mother and child. The GDM and Its Consequences for mothers and offsprings (GDMCMO) aims to establish a cohort to follow both maternal and offsprings'short-term and long-term outcomes, including fetal malformations including congenital heart diseases, birth weight, preterm birth, caesarean section delivery, body growth and neurodevelopment after birth, obesity, type 2 diabetes and impaired insulin sensitivity and secretion, lung health and allergic diseases later in life for offspring, as well as future type 2 diabetes and cardiovascular risk factors for mother after delivery. Biological samples including blood and tissue samples of mothers and children are also collected during pregnancy and after delivery.",[209,31,210,211,212,213],"Gestational Diabetes Mellitus","Neurodevelopment","Immune Development","Childhood Obesity","Host and Microbiome",[215,216,217,218],"Hyperglycaemia","Maternal health","Children","Cohort","2023-09-11",{"date":221,"type":36},"2023-09-13",{"date":223,"type":36},"2012-02-01",{"date":225,"type":21},"2038-12-31",{"name":227,"class":43},"Guangzhou Women and Children's Medical Center",{"id":229,"slug":230,"hasResults":11,"nctId":231,"briefTitle":232,"officialTitle":233,"acronym":4,"eligibilityCriteria":234,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":235,"enrollmentInfo":236,"targetDuration":4,"studyType":155,"phases":4,"briefSummary":238,"conditions":239,"keywords":242,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":247,"startDateStruct":249,"completionDateStruct":251,"leadSponsor":253,"locationsCount":4},"100396810","maternal-health-care-and-pregnancy-outcomes-in-undocumented-migrant-women-in-norway-100396810","NCT04446949","Maternal Health Care and Pregnancy Outcomes in Undocumented Migrant Women in Norway.","Documenting the Undocumented - The Use of Maternal Health Care and Pregnancy Outcomes in Undocumented Migrant Women in Norway.","Inclusion Criteria:\n\n* No registered Norwegian identity number\n* Female\n\nExclusion Criteria:\n\n* Male","50 Years",{"count":237,"type":21},70000,"Little research on the health service utilization and the health situation of undocumented pregnant migrants has been performed previously, and it is essential to obtain more information on the services given, and to examine whether residency status is a risk factor in maternal and perinatal health among migrants.This project will give new knowledge on undocumented women seeking care at the voluntary clinics and the emergency clinics (DEGPs) in Oslo and Bergen, their health care needs, and the medical follow-up they are provided. The project will present new knowledge by showing trends in undocumented pregnant migrants care seeking compared to general trends among other migrants and Norwegian residents. It will also give new knowledge on pregnancy outcomes and perinatal health in undocumented migrants compared to foreign and Norwegian born women. This approach has not previously been used to study undocumented migrants in Norway, and there are very few similar studies in other European countries. Cause and effect relations are rarely claimed in findings from observational epidemiologic studies, however the information from three different sources (voluntary clinics, emergency clinics and Medical Birth Registry) will give an overall picture of the use of primary health care in undocumented pregnant migrants, as well as a comparative assessment of maternal outcomes in this population. The proposed research will also give important knowledge on how to conduct quantitative research in a population that is difficult to reach, and that is not commonly included in research.",[240,241,31],"Transients and Migrants","Primary Health Care",[243,244,245],"Norway","Emergency care","Medical Birth Registry","2020-06-22",{"date":248,"type":36},"2020-06-25",{"date":250,"type":21},"2021-01",{"date":252,"type":21},"2028-02",{"name":254,"class":43},"University of Oslo"]