[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"premature-delivery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:premature-delivery":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100564922","effect-of-intelligent-intervention-strategies-on-self-efficacy-and-hospital-readiness-of-parents-of-preterm-infants-100564922",false,"NCT06635473","Effect of Intelligent Intervention Strategies on Self-efficacy and Hospital Readiness of Parents of Preterm Infants","Effect of Intelligent Intervention Strategies on Self-efficacy and Hospital Readiness of Parents of Preterm Infants: a Randomized Controlled Trial","Inclusion Criteria:\n\n1. Inclusion criteria for premature infants ① gestational age \\< 37 weeks；② Premature infants admitted to NICU；③ The duration of hospitalization is more than 5 days.\n2. Inclusion and exclusion criteria of primary caregivers of preterm infants ① Preterm infants admitted to neonatology and family caregivers of preterm infants with gestational age \\< 37 weeks. ② Family members who volunteer to undertake primary care tasks. ③ No mental disorders and can carry out normal language communication； ④ ≥18 years old, proficient in WeChat use；⑤ Informed consent has been signed.\n\nExclusion Criteria:\n\n1. Exclusion criteria for preterm infants ① intrauterine developmental retardation of preterm infants. ② Preterm infants with a history of major surgery. ③ Unplanned discharge, transfer, transfer or death of premature infants.\n2. Exclusion criteria for primary caregivers of preterm infants ① There are recent major mental trauma injuries caused by non-hospitalization factors. ② the caregiver suffers from serious diseases of the heart, brain, lung, kidney and other organs. 3. Shedding criteria: Caregivers who voluntarily asked to withdraw for various reasons during the study.","ALL","18 Years","100 Years",{"count":20,"type":21},84,"ESTIMATED","INTERVENTIONAL",[24],"NA","1. Construct intelligent management intervention plan for parents of preterm infants from hospital to family based on the medical and health system suitable for China's national conditions.\n2. Clinical randomized controlled trials were conducted to verify and evaluate the feasibility and application effect of the intervention program.",[27],"Premature Delivery","NOT_YET_RECRUITING","2024-10-08",{"date":31,"type":32},"2024-10-10","ACTUAL",{"date":34,"type":21},"2024-11-01",{"date":36,"type":21},"2025-10-31",{"name":38,"class":39},"Shantou University Medical College","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":48,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":4},"100542919","phase-4-screen-and-treat-strategy-for-vaginal-flora-abnormalities-in-pregnant-women-at-high-risk-of-preterm-birth-100542919","NCT06349122","Screen-and-treat Strategy for Vaginal Flora Abnormalities in Pregnant Women at High Risk of Preterm Birth","Screen-and-treat Strategy for Vaginal Flora Abnormalities by Multiplex Molecular Biology Using POC Technology in Pregnant Women at High Risk of Preterm Birth: A Multicentre, Randomized Study (AUTOP2)","AUTOP2","Inclusion Criteria:\n\n* Pregnant women over 18 years of age\n* Pregnant woman after 8 weeks and before 18 weeks of gestation (i.e. \\>=8 weeks and ≤ 18 weeks)\n* Woman who has understood the study process and objectives and agreed to sign an informed consent form;\n* With a history of preterm birth before 37 weeks of gestation or late miscarriage (high-risk preterm birth population) (A late miscarriage or late fetal loss mean foetal loss between 14 and 22 weeks of gestation)\n* Affiliated to a social security regimen or equivalent\n\nExclusion Criteria:\n\n* \\- Woman of legal age under legal protection;\n* Women deprived of their freedom for administrative or legal reasons;\n* Woman who has not signed a consent form\n* Nulliparous;\n* Ectopic pregnancy;\n* Non-evolutive pregnancy or IUFD\n* Multiple pregnancy\n* Serious fetal malformation identified at first trimester screening such as cardiopathy, exencephaly, anasarque, gastroschisis, omphalocele, diaphragmatic hernia, cerebral or spinal major anomaly.\n* Woman participating in any clinical trial or intent to participate in another clinical trial, which may have an impact on flora or on prematurity rate, with or without investigational product at any time during the conduct of this study\n* Woman presenting contraindications to the study treatments: Hypersensitivity to the active substance or to any of the excipients\n* Woman presenting uterine malformation ( unicornuate, bicornuate, full septate)\n* Woman with preterm birth history because of twin pregnancy\n* Woman having received anti-infective treatment in the week preceding inclusion","FEMALE",{"count":50,"type":21},1292,[52],"PHASE4","Preterm birth is an important cause of death and disabilities. Bacterial vaginosis (BV) is a common vaginal dysbiosis or abnormal microbiota, with a predominance of anaerobic bacteria with a lack of Lactobacillus, with various diagnosis methods. Often asymptomatic, BV increases the risk of preterm birth according to the gestational age at diagnosis. BV is usually diagnosed by conventional diagnosis such as Nugent score. Molecular diagnosis of BV has been demonstrated to be more reproducible, more accurate and to better define dysbiosis.\n\nThe main objective of the study is to evaluate the effectiveness of an innovative screen-and-treat strategy for vaginal flora abnormalities by molecular biology using a Point of Care multiplex technology before 18 weeks' gestation to reduce the rate of preterm birth in a population of pregnant women at high risk of preterm birth.\n\nThe hypothesis is that a strategy for screening and treating vaginal flora abnormalities and their recurrences using molecular biology in women with a history of prematurity or late-term abortion could be effective in reducing premature births by 40%.",[55,56,27],"Bacterial Vaginosis","Vaginal Dysbiosis",[58],"screen and treat strategy","2024-03-29",{"date":61,"type":32},"2024-04-05",{"date":63,"type":21},"2024-08",{"date":65,"type":21},"2028-01",{"name":67,"class":39},"Assistance Publique Hopitaux De Marseille"]