[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"preoperative-rehabilitation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:preoperative-rehabilitation":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100417430","multicomponent-prehabilitation-and-outcomes-in-elderly-patients-with-frailty-100417430",false,"NCT04715581","Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty","Effect of Multicomponent Prehabilitation on Early and Long-term Outcomes in Elderly Patients With Frailty After Digestive Surgery for Cancer: A Randomized-controlled Study","Inclusion criteria:\n\n1. Age ≥65 years but \\\u003C90 years;\n2. Scheduled to undergo major surgery for digestive cancer with an expected duration of 2 hours and longer, including cancers of esophagus, stomach, small intestine, colon, rectum, pancreas, liver, and biliary tract;\n3. Clinical Frailty Scale ≥5;\n4. Provide written informed consent.\n\nExclusion Criteria:\n\n1. Preoperative history of schizophrenia, epilepsy, Parkinsonism, or myasthenia gravis;\n2. Inability to communicate due to coma, profound dementia, or language barrier;\n3. Inability to participate in preoperative rehabilitation due to paralysis, fracture or other movement disorder;\n4. Inability to take oral diet due to preoperative gastrointestinal disease or other disease;\n5. Severe heart dysfunction (left ventricular ejection fraction \\\u003C30% or New York Heart Association classification IV), severe hepatic dysfunction (Child-Pugh class C), severe renal dysfunction (undergoing dialysis before surgery), or American Society of Anesthesiologists classification of grade 4 or higher;\n6. Other reasons that are considered unsuitable for study participation.","ALL","65 Years","89 Years",{"count":20,"type":21},540,"ESTIMATED","INTERVENTIONAL",[24],"NA","The study is designed to investigate the effect of a multicomponent prehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.",[27,28,29,30,31,32],"Old Age; Debility","Digestive Cancer","Surgery","Preoperative Rehabilitation","Nutrition Therapy","Outcomes",[34,35,36,37,38,39],"older patients","frailty","digestive cancer","prehabilitation","nutrition therapy","outcomes","RECRUITING","2025-07-29",{"date":43,"type":44},"2025-07-31","ACTUAL",{"date":46,"type":44},"2021-11-25",{"date":48,"type":21},"2028-12",{"name":50,"class":51},"Peking University First Hospital","OTHER"]