[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"preoperative-risk-assessment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:preoperative-risk-assessment":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,85],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100599679","copd-assessment-test-score-and-perioperative-risk-in-copd-100599679",false,"NCT07087626","COPD Assessment Test Score and Perioperative Risk in COPD","Prediction of Perioperative Complication Risk Using Chronic Obstructive Pulmonary Disease Assessment Test Score in Chronic Obstructive Pulmonary Disease Patients: A Prospective Cohort Study","COPD","Inclusion Criteria:\n\n* Patients aged between 40 and 70 years\n* Diagnosed with stable-stage Chronic Obstructive Pulmonary Disease (COPD) according to GOLD criteria\n* Scheduled for elective surgical intervention\n* Classified as ASA Physical Status II or III according to the American Society of Anesthesiologists (ASA)\n* Planned for postoperative follow-up and eligible for at least 72 hours of observation\n* Undergoing surgery with an expected duration of at least 150 minutes\n* Willing to participate voluntarily in the study\n\nExclusion Criteria:\n\n* Patients younger than 40 years or older than 70 years\n* History of COPD exacerbation within the past 4 weeks\n* Presence of severe cardiac failure (EF \\\u003C30%), end-stage renal disease, or active malignancy\n* Neurological disorders or cognitive impairments\n* Requirement for invasive mechanical ventilation in the preoperative period\n* Altered consciousness or any condition preventing completion of forms before anesthesia\n* Undergoing surgery with an expected duration longer than 150 minutes\n* Unwillingness to participate in the study voluntarily","ALL","40 Years","70 Years",{"count":21,"type":22},120,"ESTIMATED","3 Days","OBSERVATIONAL","The goal of this observational cohort study is to evaluate whether the COPD Assessment Test (CAT) score can predict the risk of perioperative respiratory complications in patients aged 40 to 70 years with diagnosed Chronic Obstructive Pulmonary Disease (COPD), undergoing elective surgical procedures lasting no longer than 150 minutes.\n\nThe main questions it aims to answer are:\n\n* Is there a statistically significant association between preoperative CAT scores and the incidence of intraoperative and early postoperative respiratory complications in COPD patients?\n* Can the CAT score be effectively used as a preoperative risk stratification tool to guide anesthetic and surgical decision-making?\n\nResearchers will compare two patient groups based on CAT scores: those with CAT \\\u003C10 and those with CAT ≥10 to determine whether higher CAT scores are associated with an increased incidence of perioperative respiratory complications.\n\nParticipants will:\n\n* Complete the CAT questionnaire during the preoperative evaluation\n* Undergo elective surgery with an expected duration of ≤150 minutes\n* Be monitored intraoperatively for bronchospasm, oxygen desaturation, and ventilation difficulty\n* Be monitored postoperatively (within the first 72 hours) for hypoxemia, reintubation, bronchospasm episodes, postoperative pneumonia, intensive care unit (ICU) admission, and length of hospital stay\n* Have perioperative clinical data collected and analyzed for comparative outcomes between CAT score subgroups",[15,27],"Preoperative Risk Assessment",[29,15,30,27],"COPD Assessment Test","Postoperative Respiratory Complications","RECRUITING","2026-05-28",{"date":34,"type":35},"2026-06-01","ACTUAL",{"date":37,"type":35},"2025-08-15",{"date":39,"type":22},"2027-02-01",{"name":41,"class":42},"Erzurum City Hospital","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100600684","phase-4-gastric-emptying-with-metoclopramide-in-glp-1-agonist-patients-undergoing-elective-surgery-100600684","NCT07100691","Gastric Emptying With Metoclopramide in GLP-1 Agonist Patients Undergoing Elective Surgery","Preoperative Metoclopramide to Enhance Gastric Emptying in Patients on Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss: A Randomised Controlled Trial With Ultrasound Assessment","GEM-GLP1RA","Inclusion Criteria:\n\n* Patients taking GLP-1 receptor agonists (for weight loss only)\n* Male and female patients aged 18 years or older\n* Able to provide written informed consent\n* ASA grade I-V\n* Scheduled for elective surgery with an expected overnight hospital stay\n\nExclusion Criteria:\n\n* Inability to provide informed consent\n* Presence of hiatus hernia\n* History of any gastric surgery\n* Pregnancy\n* Inability to lie in the right lateral decubitus position\n* Patients taking chronic opioids\n* Poorly controlled diabetes (HbA1c \\>69 mmol\u002Fmol)\n* Urgent or emergency surgery, including trauma\n* Diagnosis of Parkinson's disease\n* Allergy or intolerance to metoclopramide","18 Years",{"count":54,"type":22},80,"INTERVENTIONAL",[57],"PHASE4","This is a multicentre, investigator-blinded, randomised controlled trial evaluating whether the use of oral metoclopramide before surgery can reduce the amount of residual gastric content in patients who are taking glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for weight loss. These medications are known to slow down gastric emptying, which may increase the risk of pulmonary aspiration during anaesthesia. Patients will be randomly assigned to either receive metoclopramide 24 hours before surgery or continue with standard care. The primary outcome will be the presence or absence of residual gastric content on ultrasound before surgery. Secondary outcomes include nausea, vomiting, constipation, and any adverse effects of the medication.",[60,61,27,62],"Pulmonary Aspiration During Anaesthetic Induction","Gastric Emptying Time","Obesity (Disorder)",[64,65,66,67,68,69,70,71,72,73],"GLP-1 Receptor Agonist","Metoclopramide","Elective Surgery","Residual Gastric Content","Gastric Ultrasound","Aspiration Risk","Perioperative Management","Obesity Medications","Randomised Controlled Trial","Anaesthesia Safety","NOT_YET_RECRUITING","2025-08-01",{"date":77,"type":35},"2025-08-06",{"date":79,"type":22},"2025-08",{"date":81,"type":22},"2026-06",{"name":83,"class":42},"Mater Misericordiae University Hospital",2,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":93,"sex":17,"minAge":52,"maxAge":18,"enrollmentInfo":94,"targetDuration":4,"studyType":55,"phases":96,"briefSummary":98,"conditions":99,"keywords":102,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":113,"locationsCount":43},"100592051","stomach-processing-and-emptying-evaluation-with-diet-and-ultrasound-100592051","NCT06988397","Stomach Processing and Emptying Evaluation With Diet and Ultrasound","Food Type and Physical Activity Influence on Gastric Emptying Time Assessed by Ultrasound in Healthy Volunteers","SPEED-US","Inclusion Criteria:\n\n* Age between 18 and 40 years\n* Ability and willingness to provide written informed consent\n* Agreement to comply with study procedures, including pre-study dietary restrictions\n* No history of gastrointestinal disease\n* No recent abdominal surgery\n\nExclusion Criteria:\n\n* Lack of informed consent\n* Allergy or intolerance to any of the foods used in the study meals\n* Medical conditions known to delay gastric emptying, including:\n* Obesity (BMI \\> 30 kg\u002Fm²)\n* Diabetes mellitus\n* Gastroesophageal reflux disease (GERD)\n* Hiatal hernia\n* Bowel obstruction\n* Tube feeding\n* Active gastrointestinal disease\n* History of gastrointestinal surgery\n* Current pregnancy or breastfeeding\n* Use of medications affecting gastric motility (e.g., opioids, anticholinergics, GLP-1 receptor agonists)\n* Neuromuscular disorders impairing ability to remain in supine position for 6 hours or to walk for 30 minutes",true,{"count":95,"type":22},60,[97],"NA","Gastric content is a key risk factor for aspiration during anesthesia. Although standard fasting times are recommended, various factors-including GLP-1 receptor agonists,-can delay gastric emptying. Gastric ultrasound enables real-time, non-invasive assessment of gastric volume and can help tailor perioperative management. The aim of this study explores the effects of different meal types and physical activity on gastric emptying in healthy individuals.",[100,27,101],"Gastric Emptying","Healthy Volunteer Study",[103,104,105,106],"Gastric emptying","Gastric volume","Ultrasound","Gastric POCUS","2025-05-15",{"date":109,"type":35},"2025-05-23",{"date":111,"type":22},"2025-06-01",{"date":34,"type":22},{"name":114,"class":42},"Medical University of Warsaw"]