[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"prethrem-labour\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:prethrem-labour":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100619395","the-effects-of-adjunctive-therapy-with-vaginal-tablets-lactobacillus-acidophilus-and-a-low-dose-estriol-gynoflor-to-prolong-pregnancy-time-in-preterm-labor-a-randomized-controlled-trial-100619395",false,"NCT07344064","The Effects of Adjunctive Therapy With Vaginal Tablets Lactobacillus Acidophilus and a Low Dose Estriol (Gynoflor®) to Prolong Pregnancy Time in Preterm Labor, A Randomized Controlled Trial","Inclusion Criteria\n\n\\- Pregnant women diagnosed with preterm labor or threatened preterm labor, with a gestational age between 24 and 33 weeks, who are receiving tocolytic therapy.\n\nExclusion Criteria\n\n* Age under 18 years or 35 years and older\n* Incomplete course of Gynoflor® (less than 6 days of use)\n* Presence of contraindications to tocolysis\n* Preterm premature rupture of membranes (PPROM)\n* Unable to be contacted for follow-up\n* History of allergy to probiotics or Gynoflor®\n* Multiple gestation\n* History of short cervix diagnosed between 16-24 weeks of gestation\n* History of previous preterm labor (PTL)\n* Pregnancy achieved via assisted reproductive technology (ART)\n* Presence of fetal anomaly\n* History of antepartum hemorrhage\n* Substance abuse, including cigarette smoking, alcohol, cocaine, or heroin use\n* Other causes of preterm labor such as uterine overdistension (e.g., polyhydramnios, multifetal gestation), uterine abnormalities (e.g., myoma uteri), or systemic infections, except vaginitis",true,"FEMALE","18 Years","35 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","The study aim to study The Adjunctive therapy with vaginal tablets containing Lactobacillus acidophilus KS400 and low-dose Estriol (Gynoflor®) in addition to standard tocolytic treatment administered once daily for 6 days starting the same day as tocolytic therapy, in pregnant women diagnosed with preterm labor at gestational age 24-33 weeks .Primary Outcome is the rate of pregnancy prolongation beyond 7 days after initiation of tocolytic therapy.",[27,28,29],"Threaten Preterm","Prethrem Labour","Bacterial Vaginitis",[31,32,33,34,35],"Lactobacillus","Gynoflor","Threaten preterm","Bacterial vaginitis","Probiotic","NOT_YET_RECRUITING","2026-01-07",{"date":39,"type":40},"2026-01-15","ACTUAL",{"date":42,"type":21},"2026-02",{"date":44,"type":21},"2026-10",{"name":46,"class":47},"Queen Savang Vadhana Memorial Hospital, Thailand","OTHER"]