[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"preventing-propofol-pain-on-injection\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:preventing-propofol-pain-on-injection":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100601884","comparative-efficacy-of-iv-parecoxib-vs-lidocaine-in-reducing-propofol-injection-pain-100601884",false,"NCT07116304","Comparative Efficacy of IV Parecoxib vs Lidocaine in Reducing Propofol Injection Pain","Comparative Efficacy of Intravenous Parecoxib Versus Lidocaine in Reducing Propofol Injection Pain: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patients, ≥18 years\n* ASA grading I-II\n* Patients undergoing elective surgical procedures across all surgical specialties.\n* Can speak Arabic or English\n\nExclusion Criteria:\n\n* Difficulty in communicating.\n* Liver Cirrhosis patients\n* Renal failure or creatinine clearance (CrCl) ≤ 10umol\u002FL,\n* Known Lidocaine, parecoxib and\u002For propofol allergy.\n* patients who are not using propofol for an induction.\n* Any known contraindication to propofol, parecoxib or lidocaine. (this will include renal failure or cirrhosis of the liver as noted above)\n* Patients refusing to be involved in the study.\n* ASA(American society of anaesthesia) grading 3-6.\n* Any patient that IV access cannot be established in the dorsum of the hand.\n* Pregnant women.\n* Patients with chronic pain disorders.\n* Patients who received any form of analgesia within the last hour.",true,"ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","Propofol is the most popular IV anaesthetic agent used for induction, however one of its known side effects is causing pain on injection, the gold standard method in preventing this pain is using lidocaine prior to injecting propofol. multiple drugs have been investigated to reduce the aforementioned pain, however there has been no study comparing lidocaine to parecoxib, an NSAID.",[27],"Preventing Propofol Pain on Injection",[29,30,31,32,33],"randomised controlled trial","parecoxib","propofol","NSAIDs","pain on injection","NOT_YET_RECRUITING","2025-08-08",{"date":37,"type":38},"2025-08-11","ACTUAL",{"date":40,"type":21},"2025-08-01",{"date":42,"type":21},"2026-12-30",{"name":44,"class":45},"Oman Medical Speciality Board","OTHER_GOV"]