[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"preventive-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:preventive-therapy":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100594870","the-link-between-physical-activity-and-brain-health-in-healthy-adults-100594870",false,"NCT07025070","The Link Between Physical Activity and Brain Health in Healthy Adults","The Link Between Strength and Endurance Training and Brain Health in Healthy Adults: A Comparative Study of Former Professional Athletes and Sedentary Individuals","MINA","Inclusion Criteria:\n\n* Group A: ex-athletes and continue to perform regular physical exercise (minimum 3 days\u002Fweek of moderate-vigorous intensity).\n* Group B: sedentary individuals, (i.e., perform \\\u003C150 min of moderate intensity exercise per week or IPAQ score\\\u003C600 MET min\u002Fweek).\n* In both groups (A and B) the conditions of physical exercise or sedentary lifestyle must have been maintained for at least 6 months prior to the evaluations.\n* Not having a history of neurological or psychiatric disorder or suffering from a serious medical condition\n\nExclusion Criteria:\n\n* Medical conditions that have a high risk of associated cognitive symptoms.\n* Severe head injury with loss of consciousness within the previous 5 years.\n* Alcoholism (\\>3 alcoholic drinks per day).\n* Chronic use of anxiolytics, neuroleptics, narcotics, anticonvulsants, or sedative hypnotics.\n* Hearing or visual impairment that would preclude testing\n* History of neurological disease with clinically relevant impact on cognition (e.g. cerebrovascular disease).\n* Incidental structural brain findings with impact on cognitive impairment or survival (e.g., malignant brain tumor).\n* Presence of severe systemic disease (e.g., cancer under treatment).\n* Consumption of anabolic substances.\n* Problems understanding spoken or written Spanish.\n* Those with pacemakers or metallic implants that may interfere with the MRI.",true,"ALL","40 Years","75 Years",{"count":22,"type":23},60,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in former athletes and sedentary individuals. The main question it aims to answer is:\n\nDo former athletes have better brain structure than sedentary people? Evaluating the differences in neurodegenerative processes between competitive training and sedentary and inactivity.",[27,28,29],"Alzheimer Disease","Inactivity","Preventive Therapy",[31],"physical activity","RECRUITING","2025-06-09",{"date":35,"type":36},"2025-06-17","ACTUAL",{"date":38,"type":36},"2024-11-25",{"date":40,"type":23},"2026-09",{"name":42,"class":43},"Technical University of Madrid","OTHER"]