[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"prf\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:prf":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100641906","evaluation-of-multilayered-prf-in-comparison-with-connective-tissue-graft-by-sohn-ponchos-technique-on-peri-implant-mucosal-enhancement-in-the-esthetic-zone-100641906",false,"NCT07649239","Evaluation of Multilayered PRF in Comparison With Connective Tissue Graft by Sohn Poncho's Technique on Peri-implant Mucosal Enhancement in the Esthetic Zone","Evaluation of Multilayered PRF in Comparison With Connective Tissue Graft by Sohn Poncho's Technique on Peri-implant Mucosal Enhancement in the Esthetic Zone. A Randomized Clinical Trial","-Inclusion Criteria: Patients with single bounded missing tooth in the esthetic zone Patients in the age group of 21-65 years Patients having good oral hygiene (mean plaque score of \\\u003C 25%) and with stable periodontal status.\n\n-Exclusion Criteria: Smokers patients Patients with poor maintenance of oral hygiene, as determined by a mean plaque score of ≥ 25% despite efforts by the clinician to improve oral hygiene maintenance.\n\nPatients with medically compromised conditions like uncontrolled diabetes mellitus or any systemic diseases that may result in compromised hard and soft tissue healing.",true,"ALL","20 Years","70 Years",{"count":21,"type":22},26,"ESTIMATED","INTERVENTIONAL",[25],"NA","An effective biological seal is crucial for protecting and supporting dental implants, particularly in the anterior region for the desired esthetic outcome.PRF membrane and CTG has been utilized to improve peri-implant soft tissue thickness and increase the width of keratinized tissue around dental implants. The stability of the PRF membrane is maintained by securing it with the healing abutment of the implant. While a few longitudinal studies have assessed the benefits of using PRF membrane with Sohn's Poncho technique in the posterior region, its effectiveness in the anterior region of the mouth remains to be evaluated.",[28,29,30,31,32],"Soft Tissue","Peri-Implant Health","Soft Tissue Augmentation at Dental Implants","Connective Tissue Graft","PRF","RECRUITING","2026-06-12",{"date":36,"type":37},"2026-06-16","ACTUAL",{"date":39,"type":37},"2026-01-10",{"date":41,"type":22},"2027-02-01",{"name":43,"class":44},"Gulf Medical University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":32,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":45},"100547327","topical-application-of-prf-before-radiation-therapy-100547327","NCT06406530","Topical Application of PRF Before Radiation Therapy","Topical Application of PRF in Tooth Extraction Sockets Before Radiation Therapy for Head and Neck Cancer","Inclusion Criteria:\n\n* Head and neck cancer with planed radiation therapy\n* Bilateral tooth extraction\n* Similar tooth size\n* Atraumatic tooth extractions without flap surgery\n* Patients age above 18y of age\n\nExclusion Criteria:\n\n* Prior radiation therapy in the head and neck area\n* Prior and current therapy with bisphosphonates or equivalent modern biologics\n* Patients during pregnancy or breastfeeding","18 Years","99 Years",{"count":56,"type":22},34,[25],"The primary goal of this study is to observe whether PRP promotes the wound healing before a radiation therapy or not, compared to the natural healing of a tooth extraction socket.\n\nSecondary aim is to monitore the effect on the pain perception.",[32],[32,61,62,63,64,65],"wound healing","dentistry","oral surgery","radiation therapy","cancer","2025-04-08",{"date":68,"type":37},"2025-04-11",{"date":70,"type":37},"2023-12-01",{"date":72,"type":22},"2025-09-01",{"name":74,"class":44},"University of Giessen"]