[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"primary-ciliary-dyskinesia-pcd\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:primary-ciliary-dyskinesia-pcd":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,77,104],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100633791","developing-resource-interventions-for-healthcare-professionals-and-patients-to-improve-knowledge-about-fertility-in-primary-ciliary-dyskinesia-100633791",false,"NCT07531277","Developing Resource Interventions for Healthcare Professionals and Patients to Improve Knowledge About Fertility in Primary Ciliary Dyskinesia","REproductive Health in PRimary Ciliary Dyskinesia: Developing User-informed Clinical and Educational Resources (REPRoDUCE)","REPRoDUCE","Inclusion Criteria:\n\n1. Aged 18 years or older\n2. 'Highly likely' or confirmed diagnosis of Primary Ciliary dyskinesia, or being a healthcare professional, or representative from a stakeholder group e.g. patient led charity\n3. Able to understand and willing to sign the informed participant consent prior to participation\n\nExclusion Criteria:\n\n1. Unwilling to participate in the study\n2. Not meeting inclusion criteria\n3. Unable to understand or unwilling to sign the informed participant consent prior to participation","ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","This project will involve working with people with PCD and medical professionals to develop resources that will help patients and the people providing their care to better understand fertility and pregnancy safety in people with this condition.",[27,28,29,30],"Primary Ciliary Dyskinesia (PCD)","Fertility","Pregnancy","Health Information Exchange","NOT_YET_RECRUITING","2026-04-08",{"date":34,"type":35},"2026-04-15","ACTUAL",{"date":37,"type":21},"2026-04-01",{"date":39,"type":21},"2029-03-31",{"name":41,"class":42},"University of Southampton","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100621866","digital-physiotherapy-for-pediatric-chronic-suppurative-lung-diseases-100621866","NCT07376187","Digital Physiotherapy for Pediatric Chronic Suppurative Lung Diseases","Digital Physiotherapy Services in the Management of Pediatric Chronic Suppurative Lung Diseases: A Randomized Controlled Trial","Inclusion Criteria\n\n* children aged 6 to 12 years old\n* clinically stable with an absence of pulmonary exacerbation four weeks prior to the study's recruitment\n* adherence to attend regular medical follow-up from a pediatric pulmonologist every three months\n\nExclusion Criteria:\n\n* Cystic fibrosis\n* Immunodeficiency or asthma as their primary condition\n* Clinical evidence of cardiovascular, neuromuscular, metastatic, or psychiatric comorbidities, and neuromuscular or musculoskeletal impairments that affect mobility and the ability to follow instructions\n* Medical history of lung transplant\n* Participation in other rehabilitation programs, or attendance at regular physiotherapy ACTs sessions (\\>10 sessions in a 3-month period)\n* Lack access to the internet (e.g., no smartphone, tablet, or laptop)\n* Inability to use technological devices","6 Years","12 Years",{"count":53,"type":21},32,[24],"This is a prospective, single-center, two-arm (1:1), assessor-blinded, randomized controlled clinical trial that will be conducted in collaboration with the outpatient clinic of the third Pediatric Pulmonology Unit, \"Attikon\" University Hospital of Athens in Greece. The aim of the study is to investigate the effects of applying digital physiotherapy services in the management of specific clinical outcomes in children with chronic suppurative lung diseases, other than cystic fibrosis. The research question is whether airway clearance techniques and exercise training that are performed remotely using digital health services (DHSs) can improve functional and exercise capacity, as well as compliance with ACTs, compared to usual care. The intervention program includes airway clearance techniques (ACTs), as well as aerobic and strengthening exercises that can be implemented easily in an online setting at home with minimal equipment. The duration of the program will be 12 weeks, and the prescribed weekly regimen will consist of 50-minute remote sessions: two synchronous, supervised sessions conducted via the Vsee platform, and a minimum of one asynchronous, unsupervised session. Children will be encouraged to maintain daily adherence to the exercise protocol.",[57,58,27,59],"Chronic Suppurative Lung Disease","Protracted Bacterial Bronchitis","Non Cystic Fibrosis Bronchiectasis",[61,62,63,64,65,66],"chronic suppurative lung diseases","digital health services","pediatric","physiotherapy","remote","website","2026-01-28",{"date":69,"type":35},"2026-01-30",{"date":71,"type":21},"2026-05-01",{"date":73,"type":21},"2028-08-31",{"name":75,"class":42},"University of Thessaly",1,{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":84,"phases":4,"briefSummary":85,"conditions":86,"keywords":87,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":76},"100620433","a-qualitative-study-investigating-the-lived-experiences-and-impact-of-reproductive-issues-in-adults-with-primary-ciliary-dyskinesia-100620433","NCT07357558","A Qualitative Study Investigating the Lived Experiences and Impact of Reproductive Issues in Adults With Primary Ciliary Dyskinesia","Inclusion Criteria:\n\n* Lives in United Kingdom\n* 'likely' or 'confirmed' diagnosis of PCD\n* able and willing to sign the consent form\n\nExclusion Criteria:\n\n* unwilling to participate in the study\n* not meeting inclusion criteria",{"count":20,"type":21},"OBSERVATIONAL","Study involving undertaking research interviews with adults who have primary ciliary dyskinesia in the UK about their views and experiences of fertility, pregnancy and parenthood",[27],[88,89,90,91,92,93],"fertility","pregnancy","reproduction","parenthood","qualitative","interviews","RECRUITING","2026-01-21",{"date":97,"type":35},"2026-01-22",{"date":99,"type":35},"2025-09-02",{"date":101,"type":21},"2026-07-31",{"name":103,"class":42},"University Hospital Southampton NHS Foundation Trust",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":110,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":112,"targetDuration":114,"studyType":84,"phases":4,"briefSummary":115,"conditions":116,"keywords":117,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":127},"100241294","international-primary-ciliary-dyskinesia-pcd-registry-100241294","NCT02419365","International Primary Ciliary Dyskinesia (PCD) Registry","International Prospective Primary Ciliary Dyskinesia (PCD) Registry for Systematic Data Collection on Incidence, Clinical Presentation, Treatment and Course of the Disease","PCDregistry","Inclusion Criteria\n\nPatients of any age who fulfil the diagnostic criteria below are eligible:\n\nClinical presentation consistent with PCD and consistent findings specific for PCD in at least two of the following methods:\n\nhigh frequency video microscopic finding transmission electron microscopy finding immunofluorescence finding low nasal NO concentration\u002Fproduction demonstration of biallelic disease-causing mutations by genotyping\n\nGiven the complexity of diagnosing PCD, it is anticipated that not all patients will meet these definite diagnostic criteria. Therefore, individuals with typical clinical symptoms and only one abnormal diagnostic test are also eligible to enter the registry. These cases usually are considered to have a possible PCD diagnosis with exceptions made on an individual basis.\n\nExclusion Criteria Failure or unwillingness to give written informed consent. Missing qualification to perform legal acts or insufficient cognitive ability to give informed consent. A second disease is no exclusion criteria for including data in the PCD-Registry, especially since it is one of the fundamental goals, to learn about co-morbidities.",{"count":113,"type":21},2000,"20 Years","The purpose of the international prospective PCD Patient Registry is to systematically measure, survey and compare different aspects of PCD manifestation, course and treatment, to provide data for epidemiological research and to identify special patient groups suitable for multi-center trials.\n\nThis International PCD Registry is also part of the European Reference Network ERN-LUNG. We follow the recommendations of the EU Expert Committee on Rare Diseases (EUCERD), which recommend an international interoperability of registries and databases to pool and exchange knowledge and data on rare diseases.",[27],[27],"2022-11-25",{"date":120,"type":35},"2022-11-28",{"date":122,"type":4},"2014-01",{"date":124,"type":21},"2030-12",{"name":126,"class":42},"University Hospital Muenster",2]