[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"primary-spontaneous-pneumothorax\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:primary-spontaneous-pneumothorax":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100552324","impact-of-ambulatory-management-for-primary-spontaneous-pneumothorax-in-the-emergency-department-on-quality-of-life-100552324",false,"NCT06471608","Impact of Ambulatory Management for Primary Spontaneous Pneumothorax in the Emergency Department on Quality of Life","Impact of Ambulatory Management for Primary Spontaneous Pneumothorax in the Emergency Department on Quality of Life: a Randomized Clinical Trial","EFFI-PNO","Inclusion Criteria:\n\n* Patients aged 18 to 50 years presenting to the emergency department with a 1st episode of right or left primary spontaneous pneumothorax (PSP) of large abundance diagnosed by chest X-ray or CT scan defined according to British Thoracic Society (BTS) recommendations as a detachment greater than 2 cm over the entire height of the axillary line.\n* Patient living less than an hour from hospital and able to be accompanied for the first 48 hours\n* Patient able to understand the aims and risks of the research and to give informed, dated and signed consent\n* Patient with Internet access and able to complete online questionnaires\n* Patient affiliated to or benefiting from a social health insurance\n\nExclusion Criteria:\n\n* Small pneumothorax (≤ 2cm)\n* Suffocating pneumothorax defined by the presence of signs of respiratory distress or hemodynamic failure with indication for emergency exsufflation\n* Patient on emergency oxygen or long-term oxygen therapy\n* Traumatic pneumothorax\n* Secondary spontaneous pneumothorax\n* Bilateral pneumothorax\n* Associated fluid effusion\n* Risk-benefit balance unfavorable to outpatient treatment (comorbidities, isolated patient, difficulty understanding monitoring instructions)\n* Patient living more than one hour from hospital\n* Patients living alone or unable to be accompanied on discharge for the first 48 hours\n* Patients under legal protection\n* Pregnant or breast-feeding women\n* Patient participating in a therapeutic interventional clinical trial or in a period of exclusion linked to previous participation in a clinical trial","ALL","18 Years","50 Years",{"count":21,"type":22},386,"ESTIMATED","INTERVENTIONAL",[25],"NA","Outpatient treatment of Primary Spontaneous Pneumothorax (PSP) compared to usual inpatient management could improve quality of care and represent a more efficient, generalizable and sustainable strategy.\n\nThis multicenter, cluster-controlled, randomized interventional study with stepped wedge implementation will evaluate the impact on quality of life (between inclusion, after drain placement, and 6 months) of an ambulatory strategy for the management of large abundance primary spontaneous pneumothorax in the emergency department, compared with usual care.",[28,29,30,31],"Primary Spontaneous Pneumothorax","Quality of Life","Ambulatory Care","Chest Tube",[33,34,35,36],"Chest tube drainage","Primary spontaneous pneumothorax","Ambulatory management","Quality of life","NOT_YET_RECRUITING","2025-11-20",{"date":40,"type":41},"2025-11-26","ACTUAL",{"date":43,"type":22},"2025-12-01",{"date":45,"type":22},"2030-07",{"name":47,"class":48},"University Hospital, Strasbourg, France","OTHER",7,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100547704","early-chest-tube-removal-after-surgery-for-primary-spontaneous-pneumothorax-a-randomized-controlled-trial-100547704","NCT06411431","Early Chest Tube Removal After Surgery for Primary Spontaneous Pneumothorax: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patient undergoing video assisted thoracoscopic surgery with blebectomy\u002Fwedge resection and chemical pleurodesis for primary spontaneous pneumothorax\n* Adult patients (\\> 18 years)\n\nExclusion Criteria:\n\n* Subjects with history of chest radiation or prior ipsilateral chest surgery\n* Tuberculosis or other infectious etiology\n* Secondary spontaneous pneumothorax (COPD, cancer, cystic fibrosis, connective tissue disease, sarcoidosis, catamenial, etc.)\n* Pneumothorax due to trauma\n* Hemothorax or hydropneumothorax\n* Immunocompromised subjects: neutropenic, leukopenia, or subjects taking immunosuppressive medication such as chemotherapy, transplant medications, steroid (≥5 mg of prednisone or equivalent), etc.\n* Interstitial lung disease\n* Children (\\\u003C18)\n* Pregnant women\n* Adults unable to consent for themselves\n* Prisoners",{"count":57,"type":22},200,[25],"Video-assisted thoracoscopic surgery (VATS) with blebectomy\u002Fwedge resection plus pleurodesis is the standard of care for recurrent primary spontaneous pneumothorax (PSP) or, in certain instances, after the first episode. The chest tube from surgery is typically kept to suction until post-operative day (POD) 2 to allow for scarring of the lung to the chest to prevent recurrence. However, the scarring process takes place over a period of weeks and is there no data to support POD#2 as the best time to remove the chest tube. Also, shorter chest tube duration can lower length of stay, patient discomfort, and hospital cost.\n\nThe goal of this randomized study is to determine if early removal (POD#1) of chest tube after video-assisted thoracoscopic surgery (VATS) with blebectomy\u002Fwedge resection plus chemical pleurodesis for primary spontaneous pneumothorax (PSP):\n\n* has no worse 2-year recurrence rate compared to standard removal (POD#2)\n* will lower length of stay compared to standard removal\n* will result in less complications or re-interventions compared to standard removal\n\nParticipants will be asked to join prior to surgery. Following standard-of-care surgery, participants will be screened for randomization. If still eligible, participants will be randomized for early chest tube removal or standard removal. Early Removal will happen within 24 hours after surgery, with Standard Removal happening day 2 after surgery.\n\nParticipants will follow-up with the study team for 2 years on the following schedule:\n\n* In clinic with a chest x-ray 2 weeks after surgery\n* By phone 3 months after surgery\n* In clinic with a chest x-ray 1 year after surgery\n* In clinic with a chest x-ray 2 years after surgery",[28],"RECRUITING","2025-05-13",{"date":64,"type":41},"2025-05-16",{"date":66,"type":41},"2023-10-03",{"date":68,"type":22},"2027-12",{"name":70,"class":48},"Swedish Medical Center",1]