[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"procedural-sedation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:procedural-sedation":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,85],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100642696","personalized-music-dreaming-during-propofol-sedation-100642696",false,"NCT07638072","Personalized Music, Dreaming During Propofol Sedation","Personalized Music Increases Dreaming During Propofol Sedation: A Randomized Trial Comparing Preferred Music, Matched Non-preferred Music, and Silence","Inclusion Criteria:\n\n* Adults aged 19 years or older.\n* Scheduled to undergo an elective procedure under spinal anesthesia or peripheral nerve block with intravenous propofol sedation.\n* American Society of Anesthesiologists physical status I to III.\n* Able to provide written informed consent.\n* Able to wear closed-back headphones during the study period.\n* Able to complete postoperative interviews and study questionnaires.\n\nExclusion Criteria:\n\n* Planned general anesthesia.\n* Severe hearing impairment that would interfere with the auditory intervention.\n* Major psychiatric instability or condition that may interfere with study participation or dream assessment.\n* Expected significant intraoperative bleeding.\n* Inability to complete the required postoperative interviews or questionnaires.\n* Contraindication to propofol or other study sedative agents.\n* Refusal or withdrawal of informed consent.",true,"ALL","19 Years",{"count":20,"type":21},300,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized clinical trial will evaluate whether music delivered through closed-back headphones during intravenous propofol sedation affects dreaming and the overall sedation experience. Adults scheduled for elective procedures under spinal anesthesia or peripheral nerve block with propofol sedation will be randomly assigned to one of three groups: patient-selected preferred music, matched non-preferred music, or silence with identical headphones.\n\nThe main purpose of the study is to determine whether listening to music increases the occurrence of dream recall compared with silence, and whether personally preferred music makes recalled dreams more pleasant than matched non-preferred music. Dream recall and dream pleasantness will be assessed after recovery using a standardized interview. The study will also evaluate dream content, patient satisfaction, sedative and opioid requirements, hemodynamic variability, postoperative pain, nausea and vomiting, recovery time, and adverse events.\n\nThis study is intended to determine whether a simple, low-cost headphone-based music intervention can improve patient-centered quality of propofol sedation without compromising safety.",[27,28],"Procedural Sedation","Dreams",[30,31,32,33,34,35],"Propofol","Sedation","Music","Dreaming","Auditory Stimulation","Patient Experience","RECRUITING","2026-06-24",{"date":39,"type":40},"2026-06-26","ACTUAL",{"date":37,"type":40},{"date":43,"type":21},"2026-08-30",{"name":45,"class":46},"Wonkwang University Hospital","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":66,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":47},"100611048","anesthesia-management-in-endovascular-therapy-for-ischemic-stroke---2-100611048","NCT07235514","Anesthesia Management in Endovascular Therapy for Ischemic Stroke - 2","General Anesthesia Versus Procedural Sedation in Endovascular Therapy for Anterior Circulation Large Vessel Occlusion Stroke: A Multicenter Prospective Randomized Trial","AMETIS 2","Inclusion Criteria:\n\n* Age ≥18 years\n* Acute ischemic stroke with an occlusion of the intracranial internal carotid artery and\u002For the proximal middle cerebral artery (M1-M2) with or without association of extracranial occlusion of the cervical internal carotid artery (tandem lesion)\n* Eligible for mechanical thrombectomy according to international guidelines\n* Informed and signed consent of patient, or if he is unable to consent the consent of patient's relative or emergency procedure in the absence of relative\n* National health insurance\n\nExclusion Criteria:\n\n* Coma or altered vigilance defined as a score ≥ 2 on the level of consciousness 1A subscale of the NIHSS\n* Premorbid disability defined as a mRS \\> 2\n* Posterior circulation stroke\n* Associated cerebral hemorrhage\n* Stroke complicating another acute illness or postoperative stroke\n* Emesis at arrival in angiosuite\n* Allergy to anesthetic medication\n* Pregnant or breast-feeding women\n* Adult under the protection of the law","18 Years",{"count":58,"type":21},958,[24],"The goal of this clinical trial is to learn what is the best anesthetic management in participants with severe stroke that require a medical intervention called mechanical thrombectomy (MT) done to open the occluded brain vessel.\n\nThe main question it aims to answer is:\n\n• Is general anesthesia (GA) better than procedural sedation (PS) for improving functional performance and decrease dependance in daily life 3 months after stroke?\n\nGA (a non-arousable state induced by anesthetic medications that require respiratory assistance) or PS (a state of reduced arousal induced by lesser dose of anesthetic medications that do not require respiratory assistance) are both used for MT. GA enables strict immobility that could facilitate the conduct of MT but lessen blood pressure and blood flow in the brain. PS provides less drop in blood pressure but MT could be more difficult due to possible movement and breathing may be decreased.\n\nResearchers will compare GA with PS to see which one is better for MT success and for the functional consequences of stroke.\n\nParticipants will be treated with GA or PS for the intervention of MT and will be followed by researchers during their hospital stay and asked by a telephone interview how is their functional status 3 months after stroke.",[62,63,64,27,65],"Ischemic Stroke","Anterior Cerebral Circulation","General Anesthesia","Thrombectomy",[67,68,69,70,71,72,73,74],"Ischemic stroke","anterior circulation","mechanical thrombectomy","anesthetic strategy","general anesthesia","procedural sedation","functional outcome","large vessel occlusion stroke","NOT_YET_RECRUITING","2025-11-17",{"date":78,"type":40},"2025-11-19",{"date":80,"type":21},"2025-12-01",{"date":82,"type":21},"2029-03-01",{"name":84,"class":46},"University Hospital, Clermont-Ferrand",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":22,"phases":94,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":47},"100609358","phase-4-remimazolam-vs-propofol-in-laser-burn-cases-100609358","NCT07213544","Remimazolam vs Propofol in Laser Burn Cases","Comparison of Remimazolam Versus Propofol for Monitored Anesthetic Care in Elective Fractional Ablative CO₂ Laser","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Undergoing both outpatient Session #1 and Session #2 of fractional ablative CO2 laser therapy\n\nExclusion Criteria:\n\n* History of previous fractional ablative laser therapy for burn scar\n* Procedure expected to last longer than 30 minutes\n* Allergy such as dextran 40 or contraindication to either of the study drugs\n* Pregnant and\u002For breastfeeding\n* Subjects who are unable to or choose not to give informed consent",{"count":93,"type":21},136,[95],"PHASE4","This randomized, single-blind, crossover study compares remimazolam and propofol for monitored anesthetic care during fractional ablative CO₂ laser therapy for burn scars. The primary aim is to assess incidence of respiratory depression, defined as a need for advanced airway maneuvers (jaw thrust\u002Fchin lift, insertion of oral or nasal airway, or bag mask ventilation), and hypopnea (respiratory rate \\\u003C 8).",[98,99,27],"Burn Scar","Hypertrophic Scarring",{"date":101,"type":40},"2025-11-20",{"date":103,"type":40},"2025-11-12",{"date":105,"type":21},"2027-01-01",{"name":107,"class":46},"Medical University of South Carolina"]