[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"prodromal-symptoms\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:prodromal-symptoms":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100449327","targeting-processing-speed-deficits-to-improve-social-functioning-and-lower-psychosis-risk-100449327",false,"NCT05131035","Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk","Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk in Adolescents at Clinical High Risk for Psychosis","SCORES","Inclusion Criteria:\n\n* Meet Clinical High Risk (CHR) criteria on the Structured Interview for Psychosis Risk Syndromes, defined by the presence of at least one attenuated positive symptom at a moderate to severe level\n* A score representing 0.5 SD below the mean on Animal Naming, Trails A or BACS: Symbol Coding from the MATRICS Consensus Cognitive Battery (MCCB).\n\nExclusion Criteria:\n\n* Any DSM 5 Schizophrenia-Spectrum diagnosis\n* Non-English speaking\n* Past or current history of a clinically significant central nervous system disorder (e.g., seizure disorder)\n* Estimated IQ\\\u003C70\n* Significant head injury\n* Significant substance abuse\n* Significant visual or auditory impairment.","ALL","14 Years","20 Years",{"count":21,"type":22},54,"ESTIMATED","INTERVENTIONAL",[25],"NA","This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and other psychotic disorders.",[28,29,30],"Psychosis","Prodromal Schizophrenia","Prodromal Symptoms",[32,33,34,35,36,37,38],"Clinical High Risk (CHR)","Processing Speed","Social Functioning","Social Impairment","Social Skills","Adolescents","Cognitive Remediation","RECRUITING","2025-11-19",{"date":42,"type":43},"2025-11-24","ACTUAL",{"date":45,"type":43},"2021-10-28",{"date":47,"type":22},"2026-05-31",{"name":49,"class":50},"Northwell Health","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":17,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":64,"studyType":65,"phases":4,"briefSummary":66,"conditions":67,"keywords":72,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":88},"100311328","youth-experiences-and-health-study-100311328","NCT03332966","Youth Experiences and Health Study","Youth Experiences and Health (YEAH) Study - Psychological Symptoms and Resources As Predictors of Mental Health Among Treatment-seeking Adolescents","YEAH","Inclusion Criteria:\n\nStart of care in adolescent mental health clinic\n\nExclusion Criteria:\n\nPrevious diagnosis of psychotic disorder","15 Years","18 Years",{"count":63,"type":22},1000,"5 Years","OBSERVATIONAL","This study aims to identify unusual experiences and psychiatric symptoms that indicate a heightened risk for severe mental disorders - especially psychoses. It is important to develop reliable questionnaire methods that are cost-effective in first-stage screening, leading to in-depth assessments and targeted care. However, existing psychosis-risk questionnaires are limited in content, intended for adults, and have been insufficiently tested for actual predictive value. Therefore we will collect a new, large dataset from an unselected group of adolescents entering psychiatric care in three major urban areas of Finland. Comprehensive national health care registers will be used to assess how well the selected experiences and symptoms predict the participants' mental health over the following few years.",[68,69,30,70,71],"Psychotic Disorders","Psychiatric Hospitalization","Cannabis Use","Trauma, Psychological",[73,74,75,76,77],"adolescent","outpatients","questionnaire","psychotic-like symptoms","psychosis risk","2024-09-23",{"date":80,"type":43},"2024-09-25",{"date":82,"type":43},"2019-12-01",{"date":84,"type":22},"2024-12-31",{"name":86,"class":87},"Finnish Institute for Health and Welfare","OTHER_GOV",3]