[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"progressive-muscle-relaxation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:progressive-muscle-relaxation":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,89],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100637389","the-effect-of-progressive-muscle-relaxation-and-deep-breathing-exercises-applied-to-palliative-care-cancer-patients-on-dyspnea-fatigue-and-self-care-behaviors-100637389",false,"NCT07619209","The Effect of Progressive Muscle Relaxation and Deep Breathing Exercises Applied to Palliative Care Cancer Patients on Dyspnea, Fatigue, and Self-Care Behaviors","Inclusion Criteria:\n\n* Being 18 years of age or older\n\nBeing literate (able to read and write)\n\nHaving no significant hearing or visual impairment that prevents communication or cooperation\n\nReceiving treatment in the palliative care unit\n\nHaving a confirmed medical diagnosis of cancer\n\nHaving a Glasgow Coma Scale (GCS) score of 10 or higher\n\nBeing able to communicate via telephone and SMS for post-discharge follow-up\n\nHaving a Common Terminology Criteria for Adverse Events (CTCAE) Dyspnea Classification of Grade 3 or below\n\nHaving an ECOG Performance Status Scale score of 3 or below\n\nHaving a Hemoglobin (Hb) value of 8 gm\u002FdL or higher\n\nVolunteering to participate in the study and providing informed consent\n\nExclusion Criteria:\n\n* Currently practicing or having recently practiced Progressive Muscle Relaxation (PMR) or deep breathing exercises actively\n\nHaving a primary respiratory system disease diagnosis (such as COPD, asthma, or pneumonia)\n\nHaving a medical diagnosis of dementia, agitation, or delirium\n\nReceiving Continuous Positive Airway Pressure (CPAP) or Bilevel Positive Airway Pressure (BiPAP) support\n\nBeing on active antipsychotic or sedative medical treatment\n\nHaving a Common Terminology Criteria for Adverse Events (CTCAE) Dyspnea Classification of Grade 4 or higher","ALL","18 Years",{"count":18,"type":19},90,"ESTIMATED","INTERVENTIONAL",[22],"NA","The purpose of this study is to evaluate the effects of Progressive Muscle Relaxation (PMR) exercises and deep breathing exercises on dyspnea, fatigue, and self-care behaviors among cancer patients receiving palliative care. Advanced-stage cancer patients frequently experience debilitating symptoms such as shortness of breath (dyspnea) and severe fatigue, which significantly impair their functional capacity and daily self-care activities. Participants in this study will be assigned to either a progressive muscle relaxation intervention group or a structured deep breathing exercise group. The study aims to determine whether these non-pharmacological relaxation techniques can effectively reduce the severity of dyspnea and fatigue, thereby improving the patients' overall self-care behaviors and physical comfort in a palliative care setting.",[25,26,27,28,29],"Cancer","Fatigue","Palliative Care","Progressive Muscle Relaxation","Patient",[27,31,28,32,33,34,35,36],"Cancer Patients","Deep Breathing Exercises","Dyspnea Management","Cancer-Related Fatigue","Self-Care Behaviors","Randomized Controlled Trial","RECRUITING","2026-05-30",{"date":40,"type":41},"2026-06-03","ACTUAL",{"date":43,"type":41},"2026-01-01",{"date":45,"type":19},"2026-12",{"name":47,"class":48},"Ankara University","OTHER",4,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":20,"phases":60,"briefSummary":61,"conditions":62,"keywords":73,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":86,"locationsCount":88},"100617334","vr-pmr-for-post-burn-symptoms-100617334","NCT07317271","VR-PMR for Post-Burn Symptoms","Virtual Reality-Enhanced Progressive Muscle Relaxation for Symptom Management in Burn Survivors","VIBE","Inclusion criteria are:\n\n* ≥18 years old;\n* sustained a burn injury in the last 6 months or longer;\n* Score high on at least one of the following: Insomnia severity index (ISI) score of ≥8, Brief Pain Inventory Short Form (BPI-SF) Pain severity score of ≥3, or PROMIS Itch Severity of ≥55;\n* own a smartphone or computer with reliable internet connection for online visits and survey completion;\n* able to comfortably wear goggles or headsets on face as determined by self-report.\n\nExclusion criteria:\n\n* Cognitive impairment (Mini Mental Status Exam (MMSE) \\\u003C 25);\n* history of motion sickness, photosensitivity, photoinduced seizures, and claustrophobia as determined by self-report;\n* uncorrected visual or hearing impairments as determined by self-report;\n* non-English speaker.",{"count":59,"type":19},34,[22],"The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors.\n\nThe main questions it aims to answer are:\n\n* Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR?\n* Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors?\n\nResearchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors.\n\nParticipants will:\n\n* Complete home-based sessions of VR-enhanced PMR\n* Complete home-based sessions of standard PMR\n* Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study\n* Use VR equipment provided for the intervention period (during the VR-PMR arm)",[63,64,65,66,67,68,69,70,71,72,28],"Burn","Chronic Pain Following Thermal Burn Injury","Non-Pharmacological Interventions","Virtual Reality","Sleep Disturbance","Anxiety","Depressive Symptoms","Fatigue Symptom","Pruritus","Burn Injury",[66,74,28,75,76,77,78,26,79,72],"Burn Survivors","Chronic Symptom Management","Pain","Itch","Sleep","Burns","2026-03-03",{"date":82,"type":41},"2026-03-05",{"date":84,"type":41},"2026-02-27",{"date":45,"type":19},{"name":87,"class":48},"Johns Hopkins University",1,{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":4,"eligibilityCriteria":95,"healthyVolunteers":96,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":97,"targetDuration":4,"studyType":20,"phases":99,"briefSummary":100,"conditions":101,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":88},"100599826","acute-effects-of-progressive-muscle-relaxation-on-brain-waves-100599826","NCT07089537","Acute Effects of Progressive Muscle Relaxation on Brain Waves","Acute Effects of Progressive Muscle Relaxation on Brain Waves, Heart Rate Variability, Muscle Tone, and Mental Stress","Inclusion Criteria:\n\n* Healthy adults\n* Age: 18 years and above\n* Body Mass Index (BMI) between 18 and 24\n* Able to remain in a semi-recumbent position for 2 hours\n\nExclusion Criteria:\n\n* Individuals with communication impairments or difficulty understanding instructions\n* Color vision deficiency\n* Open wounds or injuries on the scalp\n* Currently taking medications that affect cardiovascular or autonomic nervous system regulation\n* Muscle strain or pain",true,{"count":98,"type":19},32,[22],"In modern environments, stress is present regardless of age or social role. Stress does not always have negative effects; in fact, it is a necessary response for survival, known as the stress response. This response includes increased heart rate, blood pressure, blood glucose levels, and decreased alpha brainwave activity. These physiological changes are primarily regulated by the sympathetic and parasympathetic branches of the autonomic nervous system, enabling us to cope with environmental threats. However, when the stress response system becomes overwhelmed or imbalanced-whether due to accumulated chronic stress or acute stress-it may result in adverse effects on both physical and mental health.\n\nRelaxation techniques are non-pharmacological methods that promote parasympathetic nervous system activity. The goal is to reduce excessive arousal, alleviate anxiety, slow down thought processes, and relieve stress, thereby achieving relaxation in a natural way. These methods help lower blood pressure, improve circulation, relax muscles, and enhance concentration. Previous studies have demonstrated a correlation between relaxation and attention, suggesting that relaxation can improve attentional efficiency. Moreover, it is well-documented that executive function tends to decline under stress. Relaxation techniques are commonly incorporated into psychological therapies, yet they are more accessible, easier to practice, and can be conveniently performed at home.\n\nTherefore, the aim of this study is to investigate whether PMR can produce immediate relaxation effects as measured by EEG (cortical excitability), heart rate variability, and muscle tone, and whether it can improve performance under psychological stress. The goal is to further explore the potential application of PMR in healthy populations facing acute stress conditions.",[28],"2025-07-21",{"date":104,"type":41},"2025-07-28",{"date":106,"type":41},"2025-02-24",{"date":108,"type":19},"2025-12-31",{"name":110,"class":48},"Kaohsiung Medical University"]