[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"proliferative-diabetic-retinopathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:proliferative-diabetic-retinopathy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100617221","new-pattern-of-retinal-laser-treatment-for-pdr-100617221",false,"NCT07315802","New Pattern of Retinal Laser Treatment for PDR","A Prospective Study on a New Pattern of Retinal Laser Treatment for Proliferative Diabetic Retinopathy (PDR)","Inclusion Criteria:\n\n1. Having given free and informed consent to take part in the study.\n2. Diabetes mellitus (DM) under stable treatment during the study, aged 18y to 70y, with no significant underlying systemic diseases (such as impaired renal function, severe cardiac disease, etc.);\n3. Clinically diagnosed PDR, with the presence of neovascularization confirmed by ultra-widefield fundus photography and widefield OCT angiography.\n\nExclusion Criteria:\n\n1. Previous treatment with PRP;\n2. Previous treatment with anti-VEGF agents or corticosteroids within 3 months;\n\n2\\. Severe cataract, massive vitreous hemorrhage, or extensive preretinal hemorrhage that makes pan retinal photocoagulation impossible; 3. Unable to tolerate argon-laser retinal treatment.; 4. Vitreous macular traction or traction retinal detachment need to be performed with vitrectomy; 5. Retinal vascular occlusion, age-related macular degeneration, retinal angioma, uveitis, glaucoma, optic neuropathy, or other ocular diseases that can lead to vitreous hemorrhage and\u002For neovascularization; 6. Other conditions that the researcher found improper to be included into this study.","ALL","18 Years","70 Years",{"count":20,"type":21},300,"ESTIMATED","INTERVENTIONAL",[24],"NA","The objective of the study is to evaluate the efficacy of a new pattern of argon-laser in treating patients with proliferative diabetic retinopathy (PDR).",[27,28],"Proliferative Diabetic Retinopathy","Photocoagulation Burn to Retina","NOT_YET_RECRUITING","2026-01-16",{"date":32,"type":33},"2026-01-20","ACTUAL",{"date":35,"type":21},"2026-01-01",{"date":37,"type":21},"2029-01-31",{"name":39,"class":40},"Eye & ENT Hospital of Fudan University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":60,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":41},"100558277","single-session-vs-multiple-session-panretinal-photocoagulation-for-treatment-of-proliferative-diabetic-retinopathy-100558277","NCT06549023","Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy","Single Session vs Multiple-Session Panretinal Photocoagulation With Navigated Laser in Proliferative Diabetic Retinopathy - The SMART-PRP Study","SMART-PRP","Inclusion Criteria:\n\n* Age \\> 18 years.\n* Patients with type 1 or type 2 Diabetes Mellitus with newly diagnosed Proliferative Diabetic Retinopathy, PDR.\n* Visual acuity ≥ 0.1 Snellen.\n* CRT of less than 300 micrometer measured by OCT without cysts in the neuroretina.\n* Clear media and adequately dilated pupil for PRP.\n\nExclusion Criteria:\n\n* Intraocular surgery within the last 4 months or planned within the next 3 months.\n* Previous or current center-involved diabetic macular edema (Ci-DME).\n* Previous PRP, intravitreal treatment (IVT), or macular laser treatment in study eye.\n* Treatment with medications known to risk macular edema.\n* Media opacity preventing adequate PRP.\n* General medical condition making office laser treatment very difficult or impossible.",{"count":51,"type":21},40,[24],"Proliferative diabetic retinopathy (PDR) is the leading cause for blindness in working-age adults. The current gold standard treatment for PDR is panretinal photocoagulation (PRP). In current clinical practice, both single-session and multiple-session PRP approaches are widely accepted and utilized. The purpose of this study is to compare the safety and effectiveness of single-session and multiple-session PRP.",[27,55,56,57,58,59],"Diabetic Retinopathy","Diabetic Retinopathy Visually Threatening","Diabetic Macular Edema","Diabetes Mellitus, Type 1","Diabetes Mellitus, Type 2",[61,62,63,64,65,66,67,68,69,70,71,72,73],"Panretinal photocoagulation (PRP)","Single-session PRP","Multiple-session PRP","Navigated laser","Navilas","Central subfield retinal thickness (CRT)","Macular volume","Optical coherence tomography (OCT)","Swept-source optical coherence tomography (SS-OCT)","Wide-field fundus imaging","OCT-angiography","Retinal oximetry","Electroretinogram (ERG)","RECRUITING","2025-11-17",{"date":77,"type":33},"2025-11-18",{"date":79,"type":33},"2025-01-01",{"date":81,"type":21},"2030-12-31",{"name":83,"class":84},"Vastra Gotaland Region","OTHER_GOV"]