[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"prolonged-weaning\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:prolonged-weaning":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100598144","regional-ventilation-evaluation-during-neuro-injury-weaning-study-100598144",false,"NCT07067671","Regional Ventilation Evaluation During Neuro-injury Weaning Study","Evaluation of Regional Ventilation in Neuro-injured Patients Undergoing Weaning From Mechanical Ventilation","ReVENtS","Inclusion Criteria:\n\n* Age 18 or older\n* Hospitalized in intensive care for an acute brain injury.\n* Mechanical ventilation for more than 48 hours.\n* Ventilator withdrawal planned in the next few days\n* Social security coverage\n\nExclusion Criteria:\n\n* Pregnancy\n* Moribund patient \u002F decision to stop treatment\n* Patient under state medical aid","ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","OBSERVATIONAL","This study evaluates changes in regional lung ventilation using thoracic electrical impedance tomography (EIT) during the weaning process from mechanical ventilation in ICU patients with acute brain injury. It aims to identify predictive EIT patterns related to extubation outcomes.",[25,26,27,28,29,30],"Acute Brain Injury","Mechanical Ventilation","Prolonged Weaning","Traumatic Brain Injury","Hypoxic-Ischemic Brain Injury","Intracerebral Hemorrhage",[32,33,34,35,36,37,38,39,40,41],"Electrical Impedance Tomography","Ventilator Weaning","Neurocritical Care","ICU Monitoring","Spontaneous Breathing Trial","Extubation Failure","Respiratory Mechanics","PulmoVista","EIT","Brain-Injured Patients","NOT_YET_RECRUITING","2026-02-18",{"date":45,"type":46},"2026-02-19","ACTUAL",{"date":48,"type":21},"2026-03",{"date":50,"type":21},"2028-03",{"name":52,"class":53},"Assistance Publique - Hôpitaux de Paris","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":69,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":4},"100530378","impact-of-the-nature-and-interface-of-the-tracheostomy-cannula-on-dyspnea-in-patients-weaning-from-artificial-ventilation-in-weaning-unit-100530378","NCT06185998","Impact of the Nature and Interface of the Tracheostomy Cannula on Dyspnea in Patients Weaning From Artificial Ventilation in Weaning Unit","DYSTRACH","Inclusion Criteria:\n\n* Patient aged 18 years or older\n* Patient admitted to SRPR with respiratory and hemodynamic stability\n* Patient with a tracheostomy tube\n* Deflated balloon for more than 6 hours per day\n* Able to tolerate at least 1 hour on cap and phonation valve (deflated balloon)\n* Able to remain at least 3 consecutive hours without ventilation\n* Patient with at least one non-zero dyspnea numerical rating scale (NRS) score in the 72 hours preceding inclusion\n* Able to respond to self-administered questionnaires on dyspnea\n* Patients affiliated with a social security system or beneficiaries of such a system (excluding State Medical Assistance)\n* Patients who have given their informed consent\n* No significant expected changes in the administration of anxiolytic and analgesic treatments with anti-dyspneic properties within 2 days\n\nExclusion Criteria:\n\n* Pregnant women (verified by a blood or urine test during hospitalization for all women of childbearing age)\n* Patients deprived of liberty or under legal protection (guardianship or curatorship)\n* Patients unable to consent to the research\n* Contraindication to the use of a 7 mm tracheostomy tube\n* Patient presenting the combination of major swallowing disorders and excessive salivary secretion making the deflation of the tracheostomy tube balloon",{"count":63,"type":21},76,"INTERVENTIONAL",[66],"NA","This trial aims to assess dyspnea intensity in tracheostomized patients undergoing prolonged artificial ventilation weaning. The primary outcome is dyspnea measured by the Visual Analogue Scale (VAS-Dyspnea). A comparison between low-pressure balloon tracheostomy cannula and plated balloon cannula and four interfaces (Cap, ventilator, phonation valve, or filter) are tested. The secondary outcomes including Multidimensional Dyspnea Profile, pain, anxiety VAS, and tolerance under different interfaces. The multicenter, cross-over study involves 76 patients over 25 months, each serving as their own control. Cap is always evaluated first but the order of the three interfaces (ventilator, phonation valve, or filter) and type of cannula are chosen by randomization. The study is conducted in three weaning centers (SRPR units) at Pitié-Salpêtrière, Bligny, and Forcilles.",[27],[70,71,72],"prolonged weaning","tracheostomy","dyspnea","2024-07-18",{"date":75,"type":46},"2024-07-19",{"date":77,"type":21},"2024-09",{"date":79,"type":21},"2026-10",{"name":52,"class":53}]