[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"prosthesis-and-implant-dentistry\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:prosthesis-and-implant-dentistry":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100617207","passive-fit-of-implant-supported-complete-arch-prostheses-using-digital-workflows-100617207",false,"NCT07315620","Passive Fit of Implant-Supported Complete-Arch Prostheses Using Digital Workflows","Evaluation of Passive Fit in Implant-Supported Complete-Arch Prostheses Using Three Digital Workflows, Including an Automated AI-Assisted Protocol: A Randomized Clinical Trial","MFS03-Pdental","Inclusion Criteria:\n\n1. Adults aged 18 years or older.\n2. Patients indicated for fixed implant-supported full-arch rehabilitation in the maxilla or mandible.\n3. Presence of clinically stable, osteointegrated titanium implants suitable for prosthetic rehabilitation.\n4. Absence of clinical or radiographic signs of peri-implant disease.\n5. Ability to understand the study procedures and provide written informed consent.\n6. Willingness and ability to attend all required clinical visits and evaluations.\n\nExclusion Criteria:\n\n1. Presence of peri-implant mucositis or peri-implantitis at the time of evaluation.\n2. Implant mobility or implant positioning that prevents proper prosthetic rehabilitation.\n3. Uncontrolled systemic medical conditions that could interfere with study participation or prosthetic treatment.\n4. Cognitive, psychological, or medical conditions that limit the ability to comply with study procedures.\n5. Inability to complete the required clinical evaluations or follow the study protocol, as judged by the investigator.","ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to evaluate and compare three digital workflows for the fabrication of definitive implant-supported full-arch prostheses in adult patients requiring fixed implant rehabilitation.\n\nThe main questions it aims to answer are:\n\n* Does an automated AI-assisted digital workflow improve the passive fit of definitive full-arch implant-supported prostheses compared with manual and splint-guided alignment workflows?\n* Are there differences in marginal, geometric, mechanical, and radiographic passivity among the three digital workflows? Researchers will compare manual CBCT-STL alignment, splint-guided alignment, and automated AI-assisted CBCT-STL alignment to see if the degree of digital workflow automation affects the passive fit of definitive full-arch implant-supported prostheses.\n\nParticipants will:\n\n* Be adults (18 years and older) indicated for fixed implant-supported full-arch rehabilitation.\n* Receive a definitive, screw-retained, full-arch implant-supported prosthesis fabricated using one of the three assigned digital workflows.\n* Undergo standardized clinical and radiographic assessments at the time of definitive prosthesis placement to evaluate prosthesis passive fit.",[27],"Prosthesis and Implant Dentistry",[29,30,31,32,33,34],"Implant-Supported Prosthesis","Full-Arch Rehabilitation","Passive Fit","Digital Workflow","Computer-Aided Design and Manufacturing (CAD\u002FCAM)","AI-Assisted Workflow","RECRUITING","2026-01-08",{"date":38,"type":39},"2026-01-09","ACTUAL",{"date":41,"type":21},"2026-01-01",{"date":43,"type":21},"2027-03-01",{"name":45,"class":46},"Universidad Complutense de Madrid","OTHER"]