[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"prosthesis-survival\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:prosthesis-survival":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100634790","evaluation-of-5-year-survival-and-clinical-outcomes-in-patients-undergoing-total-knee-arthroplasty-with-a-polyethylene-tibial-component-100634790",false,"NCT07544264","Evaluation of 5-year Survival and Clinical Outcomes in Patients Undergoing Total Knee Arthroplasty With a Polyethylene Tibial Component","ALLPOLY-TKA","Inclusion Criteria:\n\n1. Male and female subjects aged ≥50 and ≤85 years who are candidates for primary cemented total knee arthroplasty based on physical examination and medical history, including a diagnosis of severe knee pain and disability due to at least one of the following conditions:\n\n   1. Primary or secondary osteoarthritis\n   2. Collagen disorders and\u002For avascular necrosis of the femoral condyle\n   3. Moderate valgus, varus, or flexion deformities (Hip-Knee-Ankle angle within ±15°).\n2. Patients who provide consent and are able to complete the scheduled study procedures and follow-up assessments.\n3. Patients who sign the informed consent approved by the Ethics Committee.\n\nExclusion Criteria:\n\n1. Patients under 50 years of age and over 85 years of age;\n2. Diagnosis of rheumatoid arthritis;\n3. Patients with a contralateral joint prosthesis on the same side;\n4. Coronal plane deformity with a Hip-Knee-Ankle (HKA) angle greater than 15 degrees in varus or valgus.","ALL","50 Years","85 Years",{"count":20,"type":21},78,"ESTIMATED","INTERVENTIONAL",[24],"NA","Total knee arthroplasty (TKA) is one of the most successful procedures in orthopedic surgery for treating advanced knee osteoarthritis, providing pain relief, functional recovery, and improved quality of life. Advances in implant design and materials have further enhanced joint kinematics and patient satisfaction.\n\nAn aging population has increased the number of elderly patients with comorbidities, potentially affecting surgical outcomes and implant longevity. Polyethylene has long been used in knee prostheses; early all-polyethylene tibial components were abandoned due to high wear and failure rates, in favor of metal-backed designs, which became the gold standard.\n\nRecently, highly cross-linked ultra-high-molecular-weight polyethylene (UHMWPE) has renewed interest in all-polyethylene tibial components, although their use remains limited. These implants offer potential advantages, including elimination of locking mechanism failures, reduced backside wear, lower costs, and possibly better load distribution.\n\nEvidence from registries, systematic reviews, and meta-analyses shows that 15-year survival of all-polyethylene tibial components is comparable or even superior to metal-backed designs, with no significant differences in clinical-functional outcomes. Additionally, all-poly components are significantly less expensive.\n\nGiven these findings, increasing their use and evaluating outcomes in Italy is warranted. The aim of the present study is to assess implant survival of the Link Symphoknee prosthesis with an all-polyethylene tibial component, along with clinical-functional outcomes and post-discharge readmission rates in patients treated at the Rizzoli Orthopaedic Institute.",[27,28],"Prosthesis Survival","Arthropathy of Knee","RECRUITING","2026-06-22",{"date":32,"type":33},"2026-06-23","ACTUAL",{"date":35,"type":33},"2026-05-13",{"date":37,"type":21},"2032-10",{"name":39,"class":40},"Istituto Ortopedico Rizzoli","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":57,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":69},"100415358","clinical-and-functional-outcome-of-the-mobilelink-acetabular-cup-system-in-the-short--mid--and-longterm-follow-up-100415358","NCT04688593","Clinical and Functional Outcome of the MobileLink Acetabular Cup System in the Short-, Mid-, and Longterm Follow-up","Inclusion Criteria:\n\n* Implantation of a MobileLink acetabular cup system and a femoral stem manufactured by Waldemar Link\n* Age ≥ 18 years\n* Fully signed patient informed cons\n\nExclusion Criteria:\n\n* Revisions\n* Body Mass Index (BMI) ≥ 40 kg\u002Fm²\n* Patient who is foreseeable not able to understand the study and the study-related circumstances\n* Patients who is foreseeable non-compliant to the treatment and the follow-ups\n* Pregnant or breast-feeding women\n* Prisoner","18 Years",{"count":50,"type":21},520,"OBSERVATIONAL","The implantation of artificial hip joints is one of the most frequently performed surgeries. Normally, patients are very satisfied with the results.\n\nThe MobileLink hip prosthesis system is a CE marked medical device. This means the the safety and performance of the prosthesis ist approved. Aim of the study is to collect clinical data about the outcome of the MobileLink hip prosthesis system under routine condition and to determine the satisfaction of the patients.",[54,55,27,56],"Osteoarthritis, Hip","Hip Osteoarthritis","Prosthesis Failure",[58],"MobileLink","2024-01-24",{"date":61,"type":33},"2024-01-25",{"date":63,"type":33},"2021-05-04",{"date":65,"type":21},"2036-01",{"name":67,"class":68},"Waldemar Link GmbH & Co. KG","INDUSTRY",2,{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":78,"targetDuration":80,"studyType":51,"phases":4,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":41},"100436197","patient-reported-outcome-measures-in-patient-underwent-total-hip-and-knee-arthroplasty-100436197","NCT04960098","Patient-reported Outcome Measures in Patient Underwent Total Hip and Knee Arthroplasty","Patient-Reported Outcome Measures in Patient Underwent Total Hip and Knee Arthroplasty in Galeazzi Orthopaedic Institute Milano","Inclusion Criteria:\n\n* male and female\n* age more than 18\n* patient underwent hip or knee arthroplasty\n\nExclusion Criteria:\n\n* age less than 18\n* comorbidity that can results in the difficulty to come back for the follow up",true,{"count":79,"type":21},5816,"10 Years","Registry of Galeazzi Orthopedic Institute: provides for the regular and systematic collection of all data (clinical and some PROMs) obtained from patients undergoing hip and knee arthroplasty to which questionnaires are proposed investigating the specific functional sphere of the joints undergoing surgery (Knee injuryOsteoarthritisOutcomeScore (KOOS-PS) and Hip injuryOsteoarthritisOutcomeScore (HOOS-PS) but also the sphere of general health (ShortForm health survey-12 (SF-12) and VisualAnalogueScale (VAS)) , in addition, of course, to the satisfaction rate.",[55,83,27],"Knee Osteoarthritis","2021-07-13",{"date":86,"type":33},"2021-07-19",{"date":88,"type":33},"2016-01-12",{"date":90,"type":21},"2050-12-31",{"name":92,"class":40},"I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio"]