[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"protein-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:protein-disease":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100424263","proteomics-study-of-mild-cognitive-impairment-and-alzheimers-disease-100424263",false,"NCT04804618","Proteomics Study of Mild Cognitive Impairment and Alzheimer's Disease","Exploring Research on Early Warning Indicators of Protein in Patients With Mild Cognitive Impairment and Alzheimer's Disease","Inclusion Criteria:\n\n1. Older than 55-year-old，male or female.\n2. patients meet the diagnosis of mild cognitive impairment (MCI) or Alzheimer's disease(AD) or whose family members were diagnoed with AD\n3. Complete self-rating scale for memory impairment (AD-8 scale)\n4. Those who agree to participate in clinical research and sign informed consent.\n\nExclusion Criteria:\n\n1. Patients with acute cardiovascular and cerebrovascular diseases, acute infections (pneumonia, urinary tract infection, oral infection, digestive tract infection), severe renal dysfunction, and uremia;\n2. Pregnant or lactating women;",true,"ALL","55 Years",{"count":20,"type":21},650,"ESTIMATED","OBSERVATIONAL","This study intends to adopt standardized and rigorous cross-sectional research, collect biological specimens (including blood, feces, urine, saliva and tongue coating) from eligible subjects, and use liquid chromatography\u002Fmass spectrometry (LC-MS\u002FMS) technology to explore early warning indicators of protein in patients with mild cognitive impairment and Alzheimer's disease",[25,26],"Alzheimer Disease, Early Onset","Protein; Disease",[28,29,30],"Alzheimer Disease","biomarker","protein","RECRUITING","2022-11-14",{"date":34,"type":35},"2022-11-15","ACTUAL",{"date":37,"type":35},"2021-06-01",{"date":39,"type":21},"2026-06-30",{"name":41,"class":42},"Guangzhou University of Traditional Chinese Medicine","OTHER"]