[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"protein-energy-malnutrition\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:protein-energy-malnutrition":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,59],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":35,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":58},"100590008","brief-title-the-role-of-nutrition-in-the-rehabilitation-of-patients-with-eating-disorders-after-a-vascular-stroke-100590008",false,"NCT06961825","Brief Title: The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke.","The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke: A Randomized Controlled Trial Investigating the Effect of Protein Supplementation on Functional Recovery, Sarcopenia, Osteopenia, and Nutritional Status in Stroke Patients With Hypoalbuminemia.","Nutristroke","Inclusion Criteria:\n\n* Age range: Adults aged 18 to 85 years\n* Diagnosis: Patients diagnosed with a stroke (cerebrovascular accident) within the last 4 to 6 weeks\n* Serum albumin levels: Patients with low serum albumin levels (\\\u003C 3.5 g \u002F dL)\n* Nutritional intervention requirement: Patients who require nutritional intervention to support rehabilitation and nutrition\n* Informed consent: Patients who have completed the consent form for participation in the study and acceptance of the intervention\n\nExclusion Criteria:\n\n* Severe infections or serious cardiopulmonary conditions: Patients with severe infections or serious cardiopulmonary conditions requiring immediate medical intervention, which may affect nutrition and rehabilitation\n* Comorbidities: Patients with comorbid conditions such as renal or liver disease\n* History of stroke or neurological conditions: Patients with a history of stroke or other neurological conditions who do not meet the criteria for rehabilitation\n* Severe mental or psychological conditions: Patients with severe mental or psychological conditions who are unable to understand or consent to participation in the study","ALL","18 Years","85 Years",{"count":21,"type":22},100,"ESTIMATED","INTERVENTIONAL",[25],"NA","Brief Summary: The main objective of this thesis is to investigate the role of nutrition - specifically the administration of protein supplements (single dose and double dose) - in the rehabilitation of stroke patients with low albumin levels in relation to sarcopenia, osteopenia and functional recovery indices. The study will follow a randomized controlled trial design, incorporating clinical observation, analysis of biochemical markers, and assessment of physical and functional parameters. Participants will be randomly assigned to one of the three groups: (1) Group 1, receiving no protein supplementation (control group), (2) Group 2, receiving a single dose of protein supplement and (3) Group 3, receiving a double dose of protein supplement. The intervention will last for at least six weeks or until the biochemical markers of albumin normalize and the patient resumes regular oral intake. Biochemical assessment with be conducted through regular nutritional evaluations including measurement of serum albumin, prealbumin, C - reactive protein, creatinine, blood glucose and glycosylated hemoglobin (HbA1c), urea, electrolytes, urine albumin and additional inflammatory markers. Bone density will be assessed using DEXA, MBSR and hip measurements to determine the potential improvements resulting from the intervention. Muscle mass will be evaluated using whole - body DEXA analysis, while muscle strength and mobility will be assessed through grip strength tests and fine gait assessments. Functional recovery will be evaluated usings standardized tools for activities of daily living (Barthel Index), mental state (Geriatric Depression Scale) and quality of life (SF - 36), as well as mobility and walking tests such as the Timed Up and Go Test and 6 - Minute Walk Test. The collected data will be analyzed using appropriate statistical tools, including comparison models (ANOVA, Mann - Whitney U test) and correlation models (Pearson - Spearman). This research is expected to enhance theoretical knowledge regarding the relationship between nutrition, biochemical markers and rehabilitation outcomes in stroke patients with hypoalbuminemia. More specifically, it aims to explore the underlying mechanisms through which nutrition affects recovery - a field that remains unexplored. Additionally, the anticipated finding may contribute to the development of clinical guidelines and therapeutic approaches for the nutritional management of patients with low albumin levels, promoting personalized nutritional strategies that support effective post - stroke rehabilitation.",[28,29,30,31,32,33,34],"Stroke","Hypoalbuminemia","Sarcopenia","Osteopenia","Malnutrition (Calorie)","Protein-energy Malnutrition","Functional Decline",[36,37,38,39,40,41,42,43,44,45],"protein supplementation","nutritional intervention","albumin levels","stroke","stroke rehabilitation","eating disorders","malnutrition","nutritional assessment","sarcopenia","osteopenia","NOT_YET_RECRUITING","2025-04-29",{"date":49,"type":50},"2025-05-08","ACTUAL",{"date":52,"type":22},"2025-05-05",{"date":54,"type":22},"2030-05-05",{"name":56,"class":57},"University of Ioannina","OTHER",1,{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":4,"eligibilityCriteria":65,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":66,"enrollmentInfo":67,"targetDuration":4,"studyType":23,"phases":69,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":58},"100560387","effect-of-a-specialized-oral-supplement-on-nutritional-status-and-quality-of-life-in-non-dialysis-ckd-100560387","NCT06576479","Effect of a Specialized Oral Supplement on Nutritional Status and Quality of Life in Non-dialysis CKD","Validation of the Therapeutic Effect and Safety of a Specialized Oral Supplement on the Nutritional Status and Quality of Life in Patients with Chronic Kidney Disease Without Replacement Therapy: (Grade G3a, G3b, G4 and G5)","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Patients with diabetic kidney with eGFR \\\u003C60 ml \u002F min \u002F 1.73m2 and ≥15 ml \u002F min \u002F 1.73m2, (stage G3a, G3b and G4 respectively)\n* Patients with protein energy expenditure (defined by serum albumin \\\u003C 3.8 g\u002Fdl)\n* Patients with protein energy expenditure (defined by 24-hour recall less than a dietary protein intake \\\u003C0.6 g\u002Fkg\u002Fd or have a consumption \\\u003C25 kcal\u002Fkg\u002Fd\n* Patients who can read and write (or primary caregiver)\n* Domicile within the metropolitan area\n\nExclusion Criteria:\n\n* Previous hospitalizations in the last month\n* Patients with serious complications (chronic infection, septicemia, cancer, HIV, Alzheimer's, uncontrolled heart failure, liver failure, cerebrovascular syndrome, malabsorption syndrome, or allergy to any ingredient in the nutritional supplement)\n* Patients with actual consumption of food supplements and \u002F or keto analogues.\n\nElimination Criteria:\n\n* Failure to attend nutritional assessment and biochemical testing at baseline, 2 months, and end of the study.\n* Failure to take the supplement \\>10% (\\>12 failed doses).\n* Diagnosis of any comorbidity during the intervention period.\n* Initiation of replacement therapy.\n* Identification of adverse effects.\n* Withdrawal of voluntary participation by the patient.\n* Death.","90 Years",{"count":68,"type":22},50,[25],"Patients whit chronic kidney disease (CKD) there is a high prevalence of nutritional disorders and negative changes in body composition, which is strongly associated with an increased risk of morbidity and mortality.",[72,73],"Chronic Kidney Diseases","Protein-Energy Malnutrition",[75,76,77],"chronic kidney disease","PEW","nutrition","RECRUITING","2024-12-16",{"date":81,"type":50},"2024-12-18",{"date":83,"type":50},"2018-07-10",{"date":85,"type":22},"2025-03",{"name":87,"class":88},"NIN Institute","INDUSTRY"]