[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"proximal-gastric-adenocarcinoma\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:proximal-gastric-adenocarcinoma":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100478806","proximal-gastrectomy-anterior-anastomosis-with-pyloroplasty-versus-esophagogastric-anastomosis-for-gastric-cancer-100478806",false,"NCT05514769","Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer","Inclusion Criteria:\n\n1. Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages.\n2. Eastern Cooperative Oncology Group performance status of 0 or 1.\n3. Adequate organ function.\n\nExclusion Criteria:\n\n1. Patients had distant metastasis.\n2. oesophageal invasion of more than 3 cm.\n3. Borrmann type 4 or large (more than 8 cm) type 3 carcinoma.\n4. Previous chemotherapy or radiation therapy for any other malignancies.","ALL","18 Years","85 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","This research is designed to compare proximal gastrectomy anterior anastomosis with pyloroplasty with esophagogastric anastomosis for gastric cancer. Gastroesophageal reflux disease, postoperative quality of life, short term outcomes, and long term outcomes will be compared.",[26,27,28],"Proximal Gastric Adenocarcinoma","Gastric Cancer","Gastroesophageal Reflux Disease","RECRUITING","2026-03-29",{"date":32,"type":33},"2026-03-31","ACTUAL",{"date":35,"type":33},"2021-01-01",{"date":37,"type":20},"2027-12-31",{"name":39,"class":40},"Nanchong Central Hospital","OTHER_GOV",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":4},"100520873","protocol-for-comparing-the-efficacy-of-three-reconstruction-methods-of-the-digestive-tract-after-proximal-gastrectomy-100520873","NCT06062225","Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract After Proximal Gastrectomy","Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract (Kamikawa Versus Single-Tract Jejunal Interposition Versus SOFY Reconstruction) After Proximal Gastrectomy","Inclusion Criteria:\n\n* Age between 20-75 years old, male or female;\n* Pathological diagnosis of preoperative endoscopic biopsy: the tumor is located in the upper 1\u002F3 of the stomach (including the esophagogastric junction), and the clinical staging of gastric cancer： Ia and Ib (T1N0M0, T1N1M0, and T2N0M0) (14) according to the eighth edition of the AJCC (15);\n* No distant metastasis observed on preoperative chest radiograph, abdominal ultrasound or upper abdominal CT;\n* ASA grade 1-3;\n* Patients without contraindications to surgery;\n* Patients and their families voluntarily signing the informed consent form and participating in the study;\n\nExclusion Criteria:\n\n* Patients diagnosed with primary tumors or distant metastasis;\n* Patients whose tumor is located in the greater curvature side of the stomach;\n* Patients with coagulation dysfunction which could not be corrected;\n* Patients who were diagnosed with viral hepatitis and cirrhosis;\n* Patients who were diagnosed with diabetes mellitus, uncontrolled or controlled with insulin;\n* Patients with organ failure such as heart, lung, liver, brain, kidney failure;\n* Patients with ascites or cachexia preoperatively in poor general conditions;\n* Patients diagnosed with immunodeficiency, immunosuppression or autoimmune diseases (such as allogeneic bone marrow transplant, immunosuppressive drugs, SLE, etc.).\n* Patients refusing to sign the informed consent of the study;","20 Years","75 Years",{"count":52,"type":20},180,[23],"The efficacy of three different reconstruction methods after proximal gastrectomy will be investigated in this study through a prospective, multicenter, randomized controlled trial.",[26,56,57,58,59],"Gastrectomy","Anastomosis","Reflux Esophagitis","Postoperative Complications","NOT_YET_RECRUITING","2023-10-03",{"date":63,"type":33},"2023-10-05",{"date":65,"type":20},"2023-10",{"date":67,"type":20},"2026-10",{"name":69,"class":70},"Changzhi People's Hospital Affiliated to Changzhi Medical College","OTHER",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":78,"enrollmentInfo":79,"targetDuration":81,"studyType":82,"phases":4,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":41},"100480678","a-prospective-observation-registry-study-on-the-alimentary-reconstruction-after-radical-proximal-gastrectomy-100480678","NCT05539105","A Prospective Observation Registry Study on the Alimentary Reconstruction After Radical Proximal Gastrectomy","STAR-PG01","Inclusion Criteria:\n\n* Aged 18-80 years\n* Tumor located in the upper or esophagogastric junction (EGJ), and curative resection with more than 1\u002F2 remant is expected to be achievable by proximal gastrectomy with D2 lymphadenectomy (also apply to multiple primary cancers);\n* Clinical stage T1NxM0 (According to AJCC-8th TNM staging system) of the upper stomach or diameter of EGJ cancer less than 4cm with invading esophgus no more than 2cm without any distant metastasis;\n* Primary lesion is pathologically diagnosed as gastric adenocarcinoma, such as papillary adenocarcinoma, tubular adenocarcinoma, mucinous adenocarcinoma, poorly cohesive carcinoma (including signet ring cell carcinoma and other variants), and mixed adenocarcinoma;\n* Preoperative performance status (ECOG，Eastern Cooperative Oncology Group) of 0 or 1\n* Preoperative ASA (American Society of Anesthesiologists) scoring: I-III\n* Sufficient organ functions\n* Written informed consent\n\nExclusion Criteria:\n\n\\-","80 Years",{"count":80,"type":20},600,"36 Months","OBSERVATIONAL","This study is designed as a prospective, real world registry study that compare the safety and efficacy of the different construction methods after radical proximal gastrectomy.",[26,85],"Reconstruction",[87,85],"Proximal gastrectomy","2022-09-13",{"date":90,"type":33},"2022-09-14",{"date":92,"type":33},"2022-08-22",{"date":94,"type":20},"2029-12-31",{"name":96,"class":70},"Shanghai Zhongshan Hospital"]