[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pseudomonas-gastrointestinal-tract-infection\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pseudomonas-gastrointestinal-tract-infection":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":36,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":5},"100289166","monocyte-profiles-in-critically-ill-patients-with-pseudomonas-aeruginosa-sepsis-100289166",false,"NCT03044223","Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis","Phenotypical Und Functional Characterization of Macrophages in Critically Ill Patients With Pseudomonas Aeruginosa Induced Sepsis","MIPSA","Inclusion Criteria:\n\n* age \\> 18 years\n* critically ill patients with sepsis\n* microbiologically proven infection with Pseudomonas aeruginosa\n\nExclusion Criteria:\n\n* life expectancy \\\u003C 24 hours\n* participation in other studies",true,"ALL","18 Years","90 Years",{"count":22,"type":23},100,"ESTIMATED","OBSERVATIONAL","The present study focuses on patients with Pseudomonas aeruginosa (PSA) sepsis. The aim of the present study is to find out whether the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype predominates in blood monocytes in critically ill patients with PSA-sepsis, and whether the severity of sepsis and outcome is associated with distinct monocyte phenotype and function.",[27,28,29,30,31,32,33,34,35],"Pseudomonas Infections","Pseudomonas Septicemia","Pseudomonas; Pneumonia","Pseudomonal Bacteraemia","Pseudomonas Urinary Tract Infection","Pseudomonas Gastrointestinal Tract Infection","Sepsis","Sepsis, Severe","Critically Ill",[37,38,39,40,41,42,43],"pseudomonas aeruginosa","critically ill patient","sepsis","monocyte","macrophage","cytokine","severity of disease","RECRUITING","2024-01-16",{"date":47,"type":48},"2024-01-17","ACTUAL",{"date":50,"type":4},"2014-08",{"date":52,"type":23},"2026-12",{"name":54,"class":55},"University of Ulm","OTHER"]