[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"psychiatric-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:psychiatric-disorders":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,16,0,[8,48,90,114,149,170,205,241,266,292,313,343,366,390,418,443],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100561883","phase-2-gaze-contingent-music-therapy-augmentation-of-cbt-for-pediatric-anxiety-100561883",false,"NCT06595953","Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety","Phase II Efficacy Study of Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety","* INCLUSION CRITERIA:\n\nIn order to be eligible to participate in this study, an individual must meet all of the following criteria:\n\n1. Ability of subject and parent to understand the study and the willingness to assent\u002Fconsent into the study.\n2. Males and females; Age 8-17\n3. Clinician confirmed diagnosis of ongoing separation anxiety disorder, generalized anxiety disorder, or social anxiety disorder. A clinician will review a KSADS-PL DSM-5 (November 2016) (Kiddie Schedule for Affective Disorders and Schizophrenia for School Aged Children) interview, which will have occurred on Protocol 01-M-0192, to confirm diagnosis\n4. Willingness to adhere to 12 weekly in-person sessions of CBT\n5. Enrolled in Protocol 01-M-0192\n6. Subjects must speak, read and write English to be able to participate\n7. All subjects will have IQ\\>70 as assessed by a WASI or assessment by trained clinical staff which will have occurred under Protocol 01-M-0192\n\nEXCLUSION CRITERIA:\n\nAn individual who meets any of the following criteria will be excluded from participation in this study:\n\n1. Current use of any psychotropic medication\n2. Ongoing participation in another treatment or intervention study\n3. Ongoing mental health treatment outside of NIH\n4. Any mental health diagnosis aside from an anxiety disorder as determined by the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS)\n5. Any serious medical conditions\n6. Restrictions that preclude in-person attendance of therapy","ALL","8 Years","17 Years",{"count":20,"type":21},150,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","Background:\n\nAnxiety disorders are becoming more common among children and teenagers. Anxiety can lead to long-term physical and mental problems, such as depression. Treatments for anxiety disorders include medications as well as cognitive behavioral therapy (CBT); CBT is a form of talking therapy. Both approaches work in only about 50 percent of cases. A new approach, called gaze-contingent music reward therapy (GCMRT), may help.\n\nObjective:\n\nTo find out whether GCMRT combined with CBT is more effective than CBT alone.\n\nEligibility:\n\nChildren aged 8 to 17 years with separation anxiety disorder; generalized anxiety disorder; or social anxiety disorder. They must be enrolled in protocol 01-M-0192.\n\nDesign:\n\nParticipants will come to the clinic once a week for 4 weeks for CBT. Sometimes the participant will meet with the doctor alone; sometimes their parent may be present. They will do some computer-based tasks: They may be asked to push a button when a target appears; they may look at pictures of faces while the computer tracks their eye movements. Participants will take questionnaires each week. They will answer questions about their anxiety symptoms, feelings, and behavior.\n\nFor the next 8 weeks, participants will participate in both CBT and 1 of 2 types of GCMRT.\n\nGCMRT is a computer-based task. Participants will look at pictures with many faces in them; while they do this, pleasant music will play and stop playing over a 12-minute period.\n\nParticipants will have a final visit in week 13. They will take questionnaires. They will do final research tasks. Each visit lasts about 2 hours.",[27,28],"Psychiatric Disorders","Anxiety Disorders",[30,31,32,33,34],"Cognitive-behavioral therapy","Attention","Anxiety","Children","Adolescents","RECRUITING","2026-06-23",{"date":38,"type":39},"2026-06-24","ACTUAL",{"date":41,"type":39},"2024-12-04",{"date":43,"type":21},"2029-10-01",{"name":45,"class":46},"National Institute of Mental Health (NIMH)","NIH",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":47},"100643868","french-validation-of-the-recovery-assessment-scale-ras-fr-100643868","NCT07667686","French Validation of the Recovery Assessment Scale (RAS-FR)","Cross-Cultural Adaptation, French Validation, and Development of Derived Versions of the Recovery Assessment Scale (RAS) for the Assessment of Subjective Recovery in Mental Health","VAL-RAS-FR","Inclusion Criteria:\n\n* Adult patient (18 years or older)\n* Receiving psychiatric care at EPSM Metz-Jury (inpatient unit, day hospital, community mental health center \\[CMP\\], or intensive home-based psychiatric care service \\[EPSIAD\\]\u002Fpost-EPSIAD follow-up)\n* Able to understand French\n* Able to complete a self-report questionnaire independently or with assistance if needed\n* Patients under legal protection measures (guardianship or curatorship) may participate with the agreement of their legal representative, when applicable\n\nExclusion Criteria:\n\n* Major cognitive impairment\n* Severe clinical condition preventing questionnaire completion or understanding of French\n* Refusal to participate\n* Prisoner or person deprived of liberty by judicial or administrative decision","18 Years",{"count":58,"type":21},260,"OBSERVATIONAL","The VAL-RAS-FR study aims to cross-culturally adapt, validate, and develop derived versions of the Recovery Assessment Scale (RAS), an internationally used self-report measure of subjective recovery in mental health. The study will include 260 adult psychiatric patients receiving care at EPSM Metz-Jury in both inpatient and outpatient settings. Participants will complete the French version of the RAS (RAS-FR), the WHOQOL-BREF, and additional self-report questionnaires. A subgroup of participants will complete the RAS-FR again after one month to assess test-retest reliability. The study will also explore existential aspects of recovery through the development of the RAS-FR-EX (Existential Extension) and support the development of a shorter version, the RAS-FR-SF (Short Form), for clinical and research purposes.",[62,27],"Mental Health",[64,65,66,67,68,69,70,71,72,73,74,75,76,77,78],"subjective recovery","psychiatric care","psychometric validation","Recovery Assessment Scale","patient-reported outcome","mental health","RAS","mental health recovery","quality of life","WHOQOL-BREF","cross-cultural adaptation","recovery-oriented care","existential recovery","RAS-FR","French validation","NOT_YET_RECRUITING","2026-06-19",{"date":82,"type":39},"2026-06-25",{"date":84,"type":21},"2026-06",{"date":86,"type":21},"2027-09",{"name":88,"class":89},"Etablissement Public de Santé Mentale de Metz-Jury","OTHER",{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":96,"eligibilityCriteria":97,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":98,"enrollmentInfo":99,"targetDuration":4,"studyType":22,"phases":101,"briefSummary":103,"conditions":104,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":47},"100563963","effectiveness-of-the-skills-program-in-the-management-of-psychiatric-disorders-100563963","NCT06622993","Effectiveness of the SKILLS Program in the Management of Psychiatric Disorders","Effectiveness of the SKILLS Program in the Management of Psychiatric Disorders: a Pilot Randomized Controlled Trial","P-SKILLS","Inclusion Criteria:\n\n* Male or female ≥ 18 years of age\n* Have at least one diagnosis of a psychiatric disorder\n* Be able to carry out psychotherapy sessions\n* Have been on stable psychiatric medication for 30 days\n* Written informed consent obtained from the participant\n* Be affiliated to a social security scheme or equivalent\n\nExclusion Criteria:\n\n* Cognitive deficits marked by a score above the 10th percentile for one or more tests in the assessment history.\n* Persons deprived of liberty by judicial or administrative decision; Persons under legal protection: guardianship or curatorship\n* Presence of a severe depressive episode\n* Be engaged in psychotherapeutic work elsewhere\n* Presence of a state of excessive deficit, making psychotherapy impossible\n* Presence of psychic decompensation (e.g. delusions) making psychotherapy impossible","100 Years",{"count":100,"type":21},60,[102],"NA","Epidemiological studies show that one person in eight suffers from at least one psychiatric disorder. Mental health is therefore a major public health issue, and care for these disorders must continue to be improved.\n\nThe management of mental disorders has long followed the traditional categorical approach of developing a treatment for a given disorder. However, researchers have recently pointed out the limits of this approach in the field of mental health. They highlight the large number of co-morbidities, the existence of aspecific disorders and the intra-diagnostic heterogeneity of patients. These factors have led them to develop a transdiagnostic approach, which focuses on the mechanisms common to the various disorders in order to treat them at the same time and thus reduce the cost of treatment.",[27],"2026-06-11",{"date":107,"type":39},"2026-06-12",{"date":109,"type":39},"2024-11-14",{"date":111,"type":21},"2026-11",{"name":113,"class":89},"University Hospital, Tours",{"id":115,"slug":116,"hasResults":11,"nctId":117,"briefTitle":118,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":22,"phases":124,"briefSummary":125,"conditions":126,"keywords":134,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":47},"100643240","the-warm-study-is-a-pilot-study-that-aims-to-investigate-the-impact-of-environmental-factors-on-acute-and-chronic-wounds-mental-illness-and-social-factors-among-people-experiencing-housing-emergencies-in-augsburg-100643240","NCT07640672","The WARM Study is a Pilot Study That Aims to Investigate the Impact of Environmental Factors on Acute and Chronic Wounds, Mental Illness, and Social Factors Among People Experiencing Housing Emergencies in Augsburg.","Impact of Environmental Factors on Acute and Chronic Wounds, Mental Illness, and Social Factors Among People Experiencing Housing Emergencies in Augsburg","WARM","Inclusion Criteria:\n\n* Age over 18\n* Existing capacity to consent to participation in the study, which will be verified and documented by the study physicians\n* Inclusion of patients who present for wound treatment at the Johanniter-Hilfsmobil, the wound consultation hour of the Clinic for Vascular Surgery at Augsburg University Hospital and\u002For the substitution outpatient clinic of the Clinic for Psychiatry, Psychotherapy and Psychosomatics at Augsburg District Hospital\n* Written consent to participate in the study has been obtained from the test subject.\n\nExclusion Criteria:\n\n* Minderjährigkeit\n* Fehlende schriftliche Einwilligung zur Studienteilnahme\n* Instabiler somatischer Zustand der Betroffenen\n* Akute Selbst- und Fremdgefährdung",{"count":123,"type":21},100,[102],"Providing healthcare to homeless people is a key and challenging task, both for society as a whole and for medical and psychosocial professionals. It must be noted that the standard healthcare system is hardly used, or can only be used to an insufficient extent, by homeless people, and therefore does not comprehensively reach this group. One low-threshold and acceptance-oriented service outside the standard care system is the Johanniter-Hilfsmobil, which was established on June 3, 2024, as an innovative approach to healthcare for homeless people in Augsburg and will be scientifically examined in the following study.\n\nThe aim is to compare acute and chronic wounds in people experiencing housing emergencies who are treated by the Johanniter-Hilfsmobil with those of patients who attend the outpatient wound clinic at the Clinic for Vascular Surgery at Augsburg University Hospital.\n\nIn addition, a saliva test will be carried out to estimate the amount and type of substance consumed, and a survey will be conducted among drug-dependent test subjects who present themselves either via the Johanniter-Hilfsmobil or via the substitution outpatient clinic of the Clinic for Psychiatry, Psychotherapy, and Psychosomatics at Augsburg District Hospital.\n\nAnother focus of research is the quantitative and qualitative analysis of the psychosocial living situation and environmental influences on users of the Johanniter-Hilfsmobil.",[127,128,129,130,131,132,27,133],"Homeless Persons","Wound and Injuries","Chronic Wound Care","Homelessness","Environmental Health","Environmental Factors","Drug Abuse\u002FDependence",[135,136,137,138,139,140],"wound care","environmental health","wound and injuries","homeless persons","psychiatric disorders","drug abuse\u002Fdependence","2026-06-05",{"date":105,"type":39},{"date":144,"type":21},"2026-06-01",{"date":146,"type":21},"2027-12-31",{"name":148,"class":89},"University Hospital Augsburg",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":153,"acronym":4,"eligibilityCriteria":154,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":98,"enrollmentInfo":155,"targetDuration":4,"studyType":22,"phases":157,"briefSummary":158,"conditions":159,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":47},"100559501","improving-mental-health-treatment-for-individuals-in-crisis-interacting-with-the-criminal-legal-system-100559501","NCT06564948","Improving Mental Health Treatment for Individuals in Crisis Interacting With the Criminal-Legal System","Inclusion Criteria:\n\n1. Treatment as Usual (TAU) arm\n\n   1. Cambridge Health Alliance (CHA) patients from the cities other than Cambridge considered to be in the \"catchment area\" of CHA (Everett, Chelsea, Somerville, Medford, Malden, and Winthrop)\n   2. Ages 18-100\n   3. Identified as having police involvement between 2009 and 2025. Treatment as Usual patients will be identified using \"targeted limited chart review methods\" used in our prior studies, \"scraping\" clinical notes in the Electronic Health Records for criminal legal involvement. Initial Identification terms, \"police\", \"arrest\", \"court\", \"summons\", \"jail\", and \"crime\" will be used to identify candidates for police involvement, downloading the sentence in which the keyword appeared and the sentence before and after. Next, an iterative process of editing of the search terms will be conducted to remove patients with negation of the keyword (\"did not commit a crime\"), and other sentence characteristics that generate false positives (\"cardiac arrest\"). Samples of the resulting dataset will be taken, accuracy assessed by examining the surrounding sentences, leading to further iterations and repetition of the process until a high level of accuracy is achieved.\n2. FSJS arm\n\n   1. Cambridge Health Alliance patients from Cambridge\n   2. Ages 18-100\n   3. Individuals who have come into contact with the Cambridge Police Department (as identified in the FSJS data) between 2009 and 2025.\n3. FSJS+Navigator arm\n\n   1. Recruited during the study period in the CHA ED\n   2. Ages 18-100\n   3. Individuals who are brought into the Emergency Department under police supervision (excluding individuals currently incarcerated)\n\n      * involuntarily brought to the Emergency Department for psychiatric evaluation because they are considered to be a risk to themselves or others (MA Law 123(12)); or\n      * the subject of a police call for service for a mental health issue who are willingly admitted to the Emergency Department\n\nExclusion Criteria\n\n1. Treatment as Usual (TAU) arm\n\n   1. Cambridge Health Alliance patients residing in the City Cambridge are excluded from the TAU arm\n   2. Under the age of 18\n   3. Individuals with no identified criminal legal system contact during the study time period (no criminal legal involvement found in the targeted limited chart review method).\n   4. Any individual incarcerated at the Middlesex Jail\u002FPrison that has not been released by the end of the period of data collection (December 31, 2025).\n2. FSJS arm\n\n   1. Cambridge Health Alliance patients outside of Cambridge will be excluded from the FSJS arm\n   2. Under the age of 18\n   3. Any individual incarcerated at the Middlesex Jail\u002FPrison that has not been released by the end of the period of data collection (December 31, 2025)\n3. FSJS+Navigator arm\n\n   1. Under the age of 18\n   2. Any individual who becomes incarcerated during the course of the study\n   3. Individuals who enter the Emergency Department not under police supervision\n\n      * For example, individuals will be excluded who voluntarily come to the ED seeking psychiatric care because they feel they may be a risk to themselves or others\n      * Individuals brought to the ED from a jail or court ordered to the ED as an alternative to jail or prison",{"count":156,"type":21},1040,[102],"The proposed Center will leverage burgeoning real-time data linkage capabilities among health systems, Medicaid payors, and criminal legal (e.g., jail booking data, jail release data) systems, to identify individuals coming in and out of jail for suicide assessment and prevention, and to better coordinate care across these disparate systems. This Center will advance the fields of suicide prevention and criminal legal system-based mental health by solving a well-known, central problem in both fields: the inability to track and intervene with individuals moving in and out of both and often multiple systems. The goal is near-term reductions in the U.S. suicide rate.",[160,27],"Suicide Risk","2026-06-02",{"date":163,"type":39},"2026-06-04",{"date":165,"type":39},"2025-02-01",{"date":167,"type":21},"2027-09-30",{"name":169,"class":89},"Cambridge Health Alliance",{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":174,"acronym":4,"eligibilityCriteria":175,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":176,"enrollmentInfo":177,"targetDuration":4,"studyType":22,"phases":179,"briefSummary":180,"conditions":181,"keywords":188,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":4},"100631852","implementing-action-based-cognitive-remediation-for-transdiagnostic-cognitive-difficulties-in-a-tertiary-mental-health-hospital-100631852","NCT07506070","Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital","Inclusion Criteria:\n\n* Participants must have been given a diagnosis of a psychiatric disorder (such as mood anxiety, psychotic disorders, etc.\n* Participants must have reported subjective cognitive difficulties associated with their psychiatric disorder\n* Participants must be capable of providing informed consent\n* Participants must have the ability to speak and read in either English or French\n* Participants must have no changes to their medication intake (such as starting or stopping medication or changing doses) within the past month before providing consent for participation\n\nExclusion Criteria:\n\n* Participants will be excluded if they are hospitalized at the time of recruitment\n* Participants will be excluded if they have a confirmed diagnosis of an intellectual disability","60 Years",{"count":178,"type":21},160,[102],"Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning. These impairments can cause significant distress and disrupt daily functioning by preventing individuals from actively participating in school or work, maintaining healthy relationships with others, and engaging in everyday activities independently. The goal of this clinical trial is to examine if action-based cognitive remediation (ABCR) therapy, a type of cognitive training program, works to treat cognitive impairments in participants with psychiatric disorders.\n\nThe main questions it aims to answer are:\n\n* Whether the intervention will improve the thinking skills of participants with different types of psychiatric conditions\n* Whether the intervention will improve social skills and work performance\n* Can this program be easily used in a regular hospital, and do the people who take part in it find it helpful and worth their time\n* Whether the improvements from the intervention last for a long time after the training is over.\n\nResearchers will compare how much the thinking skills of participants change during an 8-week waiting period (where they get no treatment) to how much they change during the 8-week training program to see if the training makes a bigger difference in helping them think and live better.\n\nParticipants will :\n\n* Complete a series of questionnaires on memory, thinking skills, and mental health at the beginning of the study\n* Wait 8 weeks without any intervention or training\n* Complete the series of questionnaires again\n* Complete an 8-week training intervention of ABCR where they will use special computer programs to practice real-life skills and tasks like planning a meal or making an appointment\n* Complete the series of questionnaires and an additional structured interview to assess acceptability and feasibility of the intervention.\n* 3 month later, complete questionnaires for a final time.",[27,182,183,184,185,186,187],"Depression - Major Depressive Disorder","Schizophrenia and Other Psychotic Disorders","Anxiety and Mood Disorders","Bipolar and Related Disorders","PTSD - Post Traumatic Stress Disorder","Autism Spectrum Disorder",[189,190,191,27,192,193,194,195],"Transdiagnostic","Action-Based Cognitive Remediation","Cognitive Remediation Therapy","Cognitive Impairments","Cognitive Deficits","Neurocognition","Social Cognition","2026-04-15",{"date":198,"type":39},"2026-04-20",{"date":200,"type":21},"2026-05-01",{"date":202,"type":21},"2031-05-01",{"name":204,"class":89},"The Royal Ottawa Mental Health Centre",{"id":206,"slug":207,"hasResults":11,"nctId":208,"briefTitle":209,"officialTitle":209,"acronym":210,"eligibilityCriteria":211,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":212,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":214,"conditions":215,"keywords":221,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":240},"100581941","disease-biosignatures-in-alsftd-spectrum-new-impactful-biological-perspectives-beyond-clinical-approaches-100581941","NCT06856850","Disease Biosignatures in ALS\u002FFTD Spectrum: New Impactful Biological Perspectives Beyond Clinical Approaches","SPECTRALS","Inclusion Criteria:\n\n* Clinical criteria for ALS (Brooks et al., 2000; de Carvalho M., 2008), FTD (GornoTempini et al., 2011; Rascovsky et al., 2011)\n\nExclusion Criteria:\n\n* na",{"count":213,"type":21},230,"Diagnosis of ALS\u002FFTD disease spectrum is challenging because it largely relies on clinical symptoms. Identifying novel biomarkers is essential for a paradigm shift towards a more precise biological-based diagnosis. To achieve this aim, having access to proper specimens and analytical methods is crucial. Our team of experts in neurology, biology, chemistry, physics, and AI will explore ALS\u002FFTD from novel perspectives using transcriptomics, proteomics, genomics and other innovative approaches to analyzing easily accessible tissues. The seed amplification assay (SAA) will be also exploited to detect pathological TDP-43. This project aims to create disease fingerprints useful for patient stratification and monitoring of disease progression, and to evaluate the therapeutic efficacy in clinical trials, thus overcoming the limits of clinical interpretation. Discovering new biomarkers and cellular pathways will improve the diagnosis and treatment of these devastating diseases.",[216,217,218,27,219,220],"ALS (Amyotrophic Lateral Sclerosis)","FTD","Neuropathic","Idiopathic Intracranial Hypertension","Frontotemporal Dementia (FTD)",[222,223,224,225,226,227,228,229,230],"Amyotrophic lateral sclerosis","frontotemporal dementia","microbiota","miRNA","protein-NMR","TDP-43","endocytic disfunction","seed amplification assay","peripheral biomarker","2026-03-25",{"date":233,"type":39},"2026-03-30",{"date":235,"type":39},"2025-02-27",{"date":237,"type":21},"2026-08",{"name":239,"class":89},"Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta",4,{"id":242,"slug":243,"hasResults":11,"nctId":244,"briefTitle":245,"officialTitle":246,"acronym":247,"eligibilityCriteria":248,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":249,"enrollmentInfo":250,"targetDuration":4,"studyType":22,"phases":252,"briefSummary":253,"conditions":254,"keywords":255,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":257,"lastUpdatePostDateStruct":258,"startDateStruct":260,"completionDateStruct":262,"leadSponsor":264,"locationsCount":47},"100621638","virtual-reality-schema-therapy-exercises-with-parent-and-child-modes-100621638","NCT07373223","Virtual Reality Schema Therapy Exercises With Parent and Child Modes","VR-STEM: Virtual Reality Schema Therapy Exercises With Parent and Child Modes","VR-STEM","Inclusion Criteria:\n\n* 18-65 years of age\n* In treatment at a tertiary treatment facility (UCP, UMCG)\n* Whose current psychological distress is related to early life experiences as indicated by a clinician\n* Score of \\>3 on one of three schema modes on the SMI (Lobbestael et al., 2010)\n\nExclusion Criteria:\n\n* Insufficient command of the Dutch language\n* Primary diagnosis of a substance use disorder, or organic brain disease (such as dementia)\n* Unable to provide informed consent","65 Years",{"count":251,"type":21},30,[102],"The goal of this clinical trial is to develop a Virtual Reality version of a Schema Therapy exercise and test its feasibility, acceptability and potential usefulness in people with psychiatric disorders (age 18-65). The main questions the investigators aim to answer are:\n\n1. Are dialogue exercises with virtual reality mode avatars feasible, acceptable and useful?\n2. How do patients experience VR schema therapy exercises (in terms of immersion, elicited emotions, therapeutic relationship or subjective efficacy) and are the exercises potentially effective (in terms of schema mode scores, self-criticism, self-compassion and self-esteem)?\n3. In case of a potential 'effect', is this moderated by mental imagery ability?\n\nThe investigators hypothesize that 1) dialogue exercises with virtual reality mode avatars are feasible, ac-ceptable and useful according the Technology Acceptance Model (TAM; Davis, 1989); 2) patients experience high levels of immersion, elicited emotions and subjective efficacy, a strong therapeutic relationship, and show effects on schema mode scores and self-compassion and self-esteem scores; and 3) these effects are moderated by patients' mental imagery ability in such a way that patients with less mental imagery abilities benefit most.\n\nThe development of the VR version of the exercise will be done in collaboration with patients and therapists.\n\nTo test its feasibility, acceptability and potential usefulness, participants will be invited to receive one session of the exercise. During this session, they will complete some questionnaires before and after the exercise, and they will be asked about their opinions about and experiences of the exercise.",[27],[256],"Virtual Reality Schema Therapy","2026-03-24",{"date":259,"type":39},"2026-03-27",{"date":261,"type":39},"2026-02-14",{"date":263,"type":21},"2027-04-30",{"name":265,"class":89},"University Medical Center Groningen",{"id":267,"slug":268,"hasResults":11,"nctId":269,"briefTitle":270,"officialTitle":271,"acronym":4,"eligibilityCriteria":272,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":273,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":275,"conditions":276,"keywords":278,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":291},"100625067","a-multicenter-observational-study-of-lemborexant-on-insomnia-patients-with-psychiatric-disorders-100625067","NCT07417813","A Multicenter Observational Study of Lemborexant on Insomnia Patients With Psychiatric Disorders","A Multicenter, Prospective, Single-Arm, Observational Study on Effectiveness and Safety of Lemborexant on Insomnia Patients With Psychiatric Disorders","Inclusion Criteria:\n\n1. Aged 18 years and above, regardless of gender;\n2. Meet the DSM-5 diagnostic criteria for mental disorders (any type);\n3. Insomnia Severity Index (ISI) score ≥11;\n4. Have at least 7 hours of sleep time available;\n5. Able to complete the 2-month scale assessment and follow-up plan;\n6. Voluntarily sign the informed consent form;\n7. Intend to receive lemborexant treatment as judged by the clinicians\n\nExclusion Criteria:\n\n1. Mental disorder is in the acute phase as judged by clinical assessment, or the dose of other psychotropic drugs cannot be stabilized during the study;\n2. Concurrent use of ≥2 types of benzodiazepine receptor agonists (BZRAs) as insomnia treatment drugs;\n3. Previous continuous use of dual orexin receptor antagonist (DORA)-type drugs for \\>1 week;\n4. Clear suicide attempt\u002Fplan or high suicide risk as judged by the researcher;\n5. Pregnant or lactating women;\n6. Patients with narcolepsy;\n7. Patients with severe hepatic insufficiency;\n8. Currently accompanied by severe or unstable diseases of cardiovascular, respiratory, digestive and other systems;\n9. Other conditions deemed unsuitable for participation by the researcher",{"count":274,"type":21},121,"This study aims to evaluate the effectiveness and safety of lemborexant (a new dual orexin receptor antagonist) in the treatment of patients with mental disorders complicated with insomnia. The subjects are patients aged 18 years and above, who meet the DSM-5 diagnostic criteria for mental disorders and have an Insomnia Severity Index (ISI) score ≥11. They will receive lemborexant treatment for 8 weeks, with follow-up to observe the improvement of insomnia symptoms and adverse events, so as to provide real-world evidence for the clinical optimization of treatment regimens for insomnia comorbid with psychiatric disorders.",[277,27],"Insomnia",[279,27,277,280,281],"Lemborexant","Dual Orexin Receptor Antagonist","Real-World Study","2026-02-13",{"date":284,"type":39},"2026-02-18",{"date":286,"type":39},"2026-01-24",{"date":288,"type":21},"2026-12-31",{"name":290,"class":89},"Shanghai Mental Health Center",9,{"id":293,"slug":294,"hasResults":11,"nctId":295,"briefTitle":296,"officialTitle":296,"acronym":4,"eligibilityCriteria":297,"healthyVolunteers":11,"sex":298,"minAge":56,"maxAge":4,"enrollmentInfo":299,"targetDuration":4,"studyType":22,"phases":301,"briefSummary":302,"conditions":303,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":304,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":309,"leadSponsor":311,"locationsCount":4},"100605431","the-effect-of-art-therapy-on-disease-severity-and-anxiety-levels-in-inpatients-at-a-psychiatry-clinic-100605431","NCT07162428","The Effect of Art Therapy on Disease Severity and Anxiety Levels in Inpatients at a Psychiatry Clinic","Inclusion Criteria:\n\nAge 18 years or older.\n\nCurrently hospitalized in the psychiatry clinic and expected to remain hospitalized during the study period.\n\nNo medical condition such as intellectual disability or organic mental disorder that would interfere with the administration of scales and tests.\n\nA PANSS score of ≤62 (since a score of 61 is considered the remission criterion in schizophrenia, patients scoring 62 or below will be included).\n\nA score between 5-18 on the Young Mania Rating Scale.\n\nReceiving treatment in the clinic for at least 3 days.\n\nProviding verbal and\u002For written informed consent to participate in the study.\n\nExclusion Criteria:\n\nBeing in an acute psychotic episode or having severe psychotic symptoms (e.g., severe delusions, hallucinations) making the patient unsuitable for group participation.\n\nClinical conditions involving excessive agitation or homicidal risk that make group participation inappropriate.\n\nInability to actively participate in art therapy due to visual, hearing, or severe motor impairments.\n\nPatients for whom discharge is planned during the clinical course (e.g., those scheduled for discharge in less than 3 days).\n\nDiagnosis of an organic mental disorder (e.g., dementia, delirium).\n\nSevere physical illness or motor impairment preventing participation in group activities","MALE",{"count":300,"type":21},48,[102],"The aim of this study is to examine the effect of art therapy applied to inpatients in the psychiatry ward on disease severity and anxiety levels. Art therapy is considered a complementary intervention that can positively contribute to the psychiatric recovery process by facilitating the expression and regulation of an individual's emotional state.\n\nThis research will be conducted with a randomized controlled design and aims to demonstrate the effectiveness of art therapy practices within the clinical process through objective data. The originality of the study lies in the fact that art therapy will be implemented with individuals hospitalized in an acute psychiatric ward. In this respect, the study provides the opportunity to evaluate the applicability of art therapy even during crisis periods and carries the potential to make significant practice-oriented contributions to the field of mental health.",[27],"2025-09-17",{"date":306,"type":39},"2025-09-23",{"date":308,"type":21},"2025-09-15",{"date":310,"type":21},"2025-11-01",{"name":312,"class":89},"Koç University",{"id":314,"slug":315,"hasResults":11,"nctId":316,"briefTitle":317,"officialTitle":318,"acronym":319,"eligibilityCriteria":320,"healthyVolunteers":321,"sex":16,"minAge":56,"maxAge":249,"enrollmentInfo":322,"targetDuration":4,"studyType":22,"phases":324,"briefSummary":325,"conditions":326,"keywords":328,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":334,"lastUpdatePostDateStruct":335,"startDateStruct":337,"completionDateStruct":339,"leadSponsor":341,"locationsCount":4},"100605118","chewing-gum-as-a-therapeutic-intervention-for-the-management-of-hypersalivation-100605118","NCT07158359","Chewing Gum as a Therapeutic Intervention for the Management of Hypersalivation","Chewing Gum as a Therapeutic Intervention for the Management of Hypersalivation : a Pilot Study L'Utilisation du Chewing-gum Dans la Prise en Charge de l'hypersialorrhée : Une étude Pilote","Chew Daily","Inclusion Criteria:\n\n* Adults aged 18 to 65 years.\n* Hospitalized at Cadillac Hospital, either in full inpatient care or at the rehabilitation facility, excluding the UHSA.\n* Experiencing iatrogenic hypersalivation induced by psychotropic medications.\n* Salivary flow causing functional impairment for the patient, or observed by family members or healthcare providers.\n* With or without pharmacological management of hypersalivation.\n* Individuals under legal protective measures may be included.\n* Provided written informed consent prior to participation.\n\nExclusion Criteria:\n\n* Anatomical\u002Fmorphological anomaly affecting mastication\u002Fswallowing\n* Swallowing disorder of organic etiology (e.g., neurological deficit due to stroke, neurodegenerative disease, oropharyngeal surgery, etc.)\n* Known risk of aspiration with liquids\n* Patient refusal of chewing gum or inability to obtain consent (e.g., non-communicative patients)\n* Oral\u002Fdental condition preventing mastication",true,{"count":323,"type":21},46,[102],"Psychiatric disorders often require specific treatments, usually involving medications called psychotropic drugs. While effective, these medications can cause significant side effects. One of the most common is hypersalivation (excess saliva), which can make swallowing difficult and be very uncomfortable in daily life.\n\nCurrent medication-based solutions are often not very effective and may cause additional side effects. For this reason, we are exploring a different approach: using chewing gum as a form of rehabilitation.\n\nThe goal of this study is to determine whether chewing gum can help reduce excessive saliva. To do this, we will compare two groups: one that will follow a swallowing rehabilitation program including chewing gum, and another that will not.\n\nWe hope this simple, non-drug-based approach will improve the management of hypersalivation. More broadly, this research aims to highlight innovative and accessible solutions in psychiatry, showing that alternative strategies-sometimes very simple ones-can also be effective.",[327,27],"Hypersialorrhea (Excessive Salivation)",[329,330,331,332,333],"Rehabilitation","occupational therapy","pilot study","chewing gum mastication","non-pharmacological treatment","2025-08-28",{"date":336,"type":39},"2025-09-05",{"date":338,"type":21},"2025-09",{"date":340,"type":21},"2026-12",{"name":342,"class":89},"Centre Hospitalier de Cadillac",{"id":344,"slug":345,"hasResults":11,"nctId":346,"briefTitle":347,"officialTitle":347,"acronym":348,"eligibilityCriteria":349,"healthyVolunteers":11,"sex":16,"minAge":350,"maxAge":4,"enrollmentInfo":351,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":352,"conditions":353,"keywords":354,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":357,"lastUpdatePostDateStruct":358,"startDateStruct":360,"completionDateStruct":362,"leadSponsor":364,"locationsCount":47},"100594743","psychiatric-disorders-in-addiction---interest-of-screening-and-influence-on-relapse-100594743","NCT07023419","Psychiatric Disorders in Addiction - Interest of Screening and Influence on Relapse","Psyaddict","Inclusion Criteria:\n\n* Subject aged ≥16\n* Having been hospitalized in the complex withdrawal unit of the Strasbourg psychiatric clinic during the period from January 1, 2024 to November 1, 2024\n\nExclusion Criteria:\n\n* Refusal to participate in the study","16 Years",{"count":123,"type":21},"In complex detoxification hospital units, patients receive a common care system (interviews, therapeutic workshops, support for discharges, etc.). In the event of a relapse during hospitalization, i.e., a relapse into addiction, hospital care is called into question, and discharge is generally considered. A key care issue is therefore to prevent these relapses by identifying risk profiles to strengthen their management. According to studies, psychiatric diagnoses increase the risk of relapse, but the investigators do not fully understand which ones or to what extent.\n\nThe objective of this study is to analyze the influence of psychiatric diagnoses on the risk of relapse. This would allow for adapting the care of these patients to reduce this risk. The investigators are also seeking to study the value of screening questionnaires in improving the reliability of psychiatric diagnoses.",[27],[27,355,356],"Addiction","Complex detox","2025-06-17",{"date":359,"type":39},"2025-06-22",{"date":361,"type":39},"2024-12-16",{"date":363,"type":21},"2026-10-16",{"name":365,"class":89},"University Hospital, Strasbourg, France",{"id":367,"slug":368,"hasResults":11,"nctId":369,"briefTitle":370,"officialTitle":371,"acronym":372,"eligibilityCriteria":373,"healthyVolunteers":11,"sex":16,"minAge":350,"maxAge":374,"enrollmentInfo":375,"targetDuration":4,"studyType":22,"phases":377,"briefSummary":379,"conditions":380,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":381,"lastUpdatePostDateStruct":382,"startDateStruct":384,"completionDateStruct":386,"leadSponsor":388,"locationsCount":47},"100520929","phase-2-efficacy-of-melatonin-low-dose-quetiapine-or-placebo-in-patients-with-psychiatric-disorders-and-comorbid-insomnia-100520929","NCT06062953","Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients With Psychiatric Disorders and Comorbid Insomnia","Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients With Psychiatric Disorders and Comorbid Insomnia: a Randomized Clinical Trial","MEL-QUE","Inclusion Criteria:\n\n* 16 to 64 years of age\n* ICD-10 diagnosis of a current or previous mental or behavioral disorder (F20-F69, F84, F90-95)\n* For the diagnoses F84 and F90 a previous period of treatment with melatonin is required\n* For the 16-17 years old: Non-pharmacological treatment options including sleep hygiene education, weighted blanket or other gravity products have been tested with insufficient effect\n* Self-reported sleep difficulties at least three times per week in the preceding 3 months\n* Insomnia Severity Index score ≥11\n* Women of childbearing potential: negative pregnancy test at baseline and use of highly effective contraception measures\n* Informed consent\n\nExclusion Criteria:\n\n* Current treatment with melatonin or quetiapine\n* Severe somatic comorbidity\n* BMI ≥ 35 kg\u002Fm2\n* Breastfeeding\n* Alcohol and\u002For substance dependency within the last 3 months\n* Inadequate Danish language skills\n* Not able to make an informed consent\n* Increased cardiac risk as assessed by presence of cardiac risk factors, cardiac symptoms, or prolonged QT-interval at baseline ECG","64 Years",{"count":376,"type":21},255,[24,378],"PHASE3","The goal of this investigator-initiated, randomized, blinded, 3-armed placebo-controlled, pragmatic, clinical superiority trial is to examine the efficacy of melatonin or low-dose quetiapine versus placebo for treatment of insomnia in patients with psychiatric disorders. The aims of the study are:\n\n* To examine the efficacy of melatonin or low-dose quetiapine versus placebo for treatment of insomnia\n* To examine how melatonin or low-dose quetiapine affects global symptom severity, sleep quality, psychosocial functioning and subjective well-being.\n\nParticipants will receive six weeks of treatment with either melatonin, quetiapine or placebo followed by a brief taper off.",[27,277],"2025-04-21",{"date":383,"type":39},"2025-04-24",{"date":385,"type":39},"2023-09-18",{"date":387,"type":21},"2029-02-28",{"name":389,"class":89},"Lone Baandrup",{"id":391,"slug":392,"hasResults":11,"nctId":393,"briefTitle":394,"officialTitle":395,"acronym":396,"eligibilityCriteria":397,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":398,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":400,"conditions":401,"keywords":404,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":409,"lastUpdatePostDateStruct":410,"startDateStruct":412,"completionDateStruct":414,"leadSponsor":416,"locationsCount":47},"100583665","incidence-of-body-dysmorphic-disorder-bdd-in-a-population-of-patients-undergoing-orthognathic-surgery-100583665","NCT06879275","Incidence of Body Dysmorphic Disorder (BDD) in a Population of Patients Undergoing Orthognathic Surgery","Incidence of Body Dysmorphic Disorder (BDD) in a Population of Patients Undergoing Orthognathic Surgery: a Prospective Study","IBDOS","Inclusion Criteria:\n\n* Patients who are candidates for orthognathic surgery\n* Age: 18 to 50 years;\n* Informed consent\n\nExclusion Criteria:\n\n* \\- Patients diagnosed with another psychiatric pathology\n* Patients affected by syndromes involving the cervical-facial district\n* Patients affected by clefts\n* Patients affected by OSAS and candidates for orthognathic surgery for this indication\n* Patients affected by connective tissue disorders (e.g. Ehler-Danlos, scleroderma, etc.)\n* Patients candidates for orthognathic surgery due to facial trauma",{"count":399,"type":21},90,"Assessment of the incidence of Body dismorphic disorder in a population candidated to orthognathic surgery",[402,27,403],"Orthognathic Surgical Procedures","Prognathism",[405,406,407,408],"orthognatic surgery","body dismorphic disorder","prognathism","aesthetic surgery","2025-03-13",{"date":411,"type":39},"2025-03-17",{"date":413,"type":21},"2025-05-01",{"date":415,"type":21},"2030-01-01",{"name":417,"class":89},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS",{"id":419,"slug":420,"hasResults":11,"nctId":421,"briefTitle":422,"officialTitle":423,"acronym":4,"eligibilityCriteria":424,"healthyVolunteers":321,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":425,"targetDuration":4,"studyType":22,"phases":427,"briefSummary":428,"conditions":429,"keywords":430,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":434,"startDateStruct":436,"completionDateStruct":438,"leadSponsor":440,"locationsCount":442},"100481434","a-dimensional-model-for-personality-disorders-in-later-life-100481434","NCT05548946","A Dimensional Model for Personality Disorders in Later Life","Empirical Evaluation and Clinical Relevance of a Dimensional Model for Personality Disorders in Later Life","Clinical population (inpatients and outpatients)\n\nInclusion Criteria:\n\n* ONLY older adults: from the age of 65\n* Dutch speaking\n\nExclusion Criteria (as evaluated by the psychiatrists and psychologists of the participating institutions):\n\n* Severe cognitive impairment (Patients who are admitted because of cognitive impairment will be excluded from the participant pool, other than this the psychiatrists and psychologists of the participating institutions will make an evaluation of the patients' cognitive capacities)\n* Acute state of mental impairment which would interfere with the reliability of the patients' responses (for example severe psychosis), as evaluated by the psychiatrists and psychologist of the participating institutions.",{"count":426,"type":21},750,[102],"Research on personality disorders (PDs) in older adults is currently limited. This is surprising, given that PDs are also common in this age group. Moreover, PDs show high co-morbidity with other disorders (both mental and physical) and often have a negative effect on treatment. With this in mind, the conceptualization, diagnosis and treatment of PDs in older adults represents an important task for mental health care. To this end, problems with the current classification of PDs need to be tackled, as they currently complicate this task. The current DSM-5 (Diagnostic and Statistical Manual, Edition 5) (APA, 2013) categorical PD criteria are mainly based on the living conditions of younger adults and are therefore often not suited for PD diagnosis in older adults. Currently, however, a paradigm shift is taking place from a categorical to a dimensional approach of PDs. The \"Alternative Model for Personality Disorders\" (AMPD) (APA, 2013) and the approach by ICD-11 (International Classification of Diseases 11th Revision) (WHO, 2019) are examples of new, dimensional models for PDs. These models conceptualize PDs using two dimensional criteria: (1) criterion A, which captures the overall level of personality (dis)functioning and (2) criterion B which describes the PD style by pathological\u002Fmaladaptive personality traits. This paradigm shift offers the possibility to give the aging context the attention it deserves, by examining the suitability of this new dimensional conceptualization of PD among older adults.\n\nThe goal of this research is to examine whether the combined AMPD and ICD-11 dimensional approach is appropriate for use in older adults. This will be done by administering instruments capturing criterion A and B in the general population in younger (18-64) and older (65 and older) adults to evaluate their age-neutrality, as well as in a clinical sample of older (65 and older) adults, to empirically evaluate its clinical relevance in later life.",[27],[431,432,433],"Personality Psychology","Aging","Psychological Assessment",{"date":435,"type":39},"2024-12-09",{"date":437,"type":39},"2022-09-01",{"date":439,"type":21},"2025-11",{"name":441,"class":89},"Universitair Ziekenhuis Brussel",2,{"id":444,"slug":445,"hasResults":11,"nctId":446,"briefTitle":447,"officialTitle":448,"acronym":449,"eligibilityCriteria":450,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":451,"enrollmentInfo":452,"targetDuration":4,"studyType":22,"phases":453,"briefSummary":454,"conditions":455,"keywords":457,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":462,"lastUpdatePostDateStruct":463,"startDateStruct":465,"completionDateStruct":467,"leadSponsor":468,"locationsCount":47},"100398082","sleep-in-psychiatric-care-sip-a-transdiagnostic-group-based-sleep-school-as-treatment-for-comorbid-insomnia-100398082","NCT04463498","Sleep in Psychiatric Care (SIP): A Transdiagnostic Group-based Sleep-school as Treatment for Comorbid Insomnia","Sleep in Psychiatric Care: A Transdiagnostic Group-based Sleep-school as Treatment for Comorbid Insomnia","SIP","Inclusion Criteria:\n\n* Patients referred to the sleep-school at Bjørgvin DPS psychiatric hospital\n* Patients fulfilling the Diagnostic Manual for Mental Disorders (DSM-V) criteria for insomnia comorbid to moderate to severe psychiatric illness (confirmed F-diagnosis based on the International Statistical Classification of Diseases and Related Health Problems (ICD-11) diagnostic system that are used in Norway in addition to insomnia and\u002For scores of ≥19 on BDI and\u002For scores of ≥16 on BAI at the time of referral to the sleep school)\n\nExclusion Criteria:\n\n* Nightwork\n* Patients that do not fulfil the DSM-V criteria for insomnia comorbid to moderate to severe psychiatric illness (confirmed F-diagnosis based on the ICD-10 diagnostic system that are used in Norway in addition to insomnia and\u002For scores of ≥19 on BDI and\u002For scores of ≥16 on BAI at the time of referral to the sleep school)","80 Years",{"count":100,"type":21},[102],"Sleep disorders commonly co-occur with psychiatric disorders. Sleep disorders are often treated with medication or not at all in psychiatric care, although there exist a plethora of documentation of the effectiveness of sleep interventions. There is also an increase in studies showing effectiveness of sleep-interventions when the sleep disorder co-occurs with psychiatric illness. The most common and best documented treatment for insomnia is cognitive behavioral therapy for insomnia (CBTi). There is a great gap in the knowledge on how sleep disorders can be treated effectively in psychiatric care. In this project the investigators therefore seek to investigate the effect of non-pharmacological, group-based treatment in a randomized controlled trial (RCT) where sleep and psychiatric symptoms are the primary outcome measures. CBTi comprise of sleep education, sleep restriction, stimulus control and cognitive restructuring of dysfunctional thoughts about sleep.",[456,27],"Sleep Disorder; Insomnia Type",[458,459,139,460,461],"sleep disorders","insomnia","bb-glasses","group-based cognitive behavioural therapy for insomnia","2024-06-14",{"date":464,"type":39},"2024-06-18",{"date":466,"type":39},"2021-12-17",{"date":146,"type":21},{"name":469,"class":89},"Haukeland University Hospital"]