[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"psychological-flexibility\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:psychological-flexibility":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,52,79,111,139,164],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":4},"100638777","comparative-effects-of-four-brief-breathwork-and-mindfulness-interventions-on-anxiety-and-psychological-flexibility-a-4-arm-rct-100638777",false,"NCT07621042","Comparative Effects of Four Brief Breathwork and Mindfulness Interventions on Anxiety and Psychological Flexibility: A 4-Arm RCT","Effect of Brief Breathwork and Mindfulness Interventions on Anxiety, Psychological Flexibility and Physiological Variables in Spanish-Speaking University Students: a Four-Arm Randomized Controlled Trial","BREATH-4","Inclusion Criteria:\n\n* Age between 18 and 65 years (inclusive)\n* Native Spanish speaker or fluent in Spanish (sufficient to understand audio instructions and complete psychometric questionnaires)\n* Stable internet access and an electronic device (smartphone, tablet, or computer)\n* Ability to provide informed consent and commitment to the 31-day protocol and 2-month follow-up\n\nExclusion Criteria:\n\n* Active diagnosis of severe or chronic respiratory disease that prevents safe performance of breathing exercises (e.g., advanced COPD, severe uncontrolled asthma, cystic fibrosis)\n* Current diagnosis of severe psychiatric disorder (e.g., psychotic spectrum disorders, acute-phase bipolar disorder, severe major depression with suicidal risk)\n* Any acute medical condition contraindicated for voluntary alteration of breathing patterns",true,"ALL","18 Years","65 Years",{"count":22,"type":23},240,"ESTIMATED","INTERVENTIONAL",[26],"NA","This four-arm, single-blind randomized controlled trial examines the effects of four brief daily 5-minute practices over 28 days on psychological flexibility and physiological variables in Spanish-speaking adults. Participants will be randomly assigned to one of four groups: Box Breathing, Cyclic Sighing, Mindfulness focused on exhalation with the syllable \"AH\", or Conscious Cyclic Sighing. Outcomes include state and trait anxiety (STAI), positive and negative affect (PANAS), psychological flexibility (MPFI-24, Psy-Flex), and physiological variables (heart rate, respiratory rate, heart rate variability). Assessments are conducted at baseline, daily during the 28-day intervention, at post-intervention (day 31), and at 2-month follow-up.",[29,30,31],"Anxiety","Psychological Flexibility","Stress",[33,34,35,36,37,38,39],"breathworks","mindfulness","box breathing","cyclic sighing","heart rate variability","randomized controlled trial","Spanish-speaking","NOT_YET_RECRUITING","2026-06-02",{"date":43,"type":44},"2026-06-04","ACTUAL",{"date":46,"type":23},"2027-01",{"date":48,"type":23},"2027-05",{"name":50,"class":51},"Valencian International University (VIU)","OTHER",{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":24,"phases":61,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":4},"100639706","positive-psychology-based-psychoeducation-for-psychological-flexibility-and-perceived-stress-in-university-students-100639706","NCT07579767","Positive Psychology Based Psychoeducation for Psychological Flexibility and Perceived Stress in University Students","The Effect of a Multi-Component Positive Psychology-Based Psychoeducation Program on Psychological Flexibility and Perceived Stress in University Students: A Controlled Pretest-Posttest Study","Inclusion Criteria:\n\n1. Being a first-year undergraduate student in the Department of Nursing at Harran University.\n2. Volunteering to participate in the study and providing informed consent.\n3. Having no reading, comprehension, or communication difficulty that would prevent completion of the data collection tools.\n4. Being 18 years of age or older.\n\nExclusion Criteria:\n\n1. Receiving regular psychotherapy or psychoeducation during the same academic period.\n2. Having participated in a structured positive psychology-based psychoeducation or intervention program within the last 6 months.\n3. Having a history of psychiatric hospitalization within the last 3 months or having an acute psychiatric crisis or instability that would make participation in the sessions inappropriate.",{"count":60,"type":23},66,[26],"This study will test whether an 8-week multi-component positive psychology-based psychoeducation program can reduce perceived stress and improve psychological flexibility among first-year undergraduate nursing students. Eligible students who provide informed consent will be randomly assigned to either an intervention group or a waitlist control group. The intervention group will attend weekly 60-75 minute psychoeducation sessions including brief psychoeducation, experiential exercises, shared reflection, and home practice assignments. The waitlist control group will continue their usual routine during the study period and will not receive any intervention before post-test assessment. Outcomes will be assessed at baseline and immediately after the 8-week program using the Perceived Stress Scale-14 and the Acceptance and Action Questionnaire-II.",[64,30],"Stress, Psychological",[66,67,68,30,69],"Positive Psychology","Psychoeducation","Perceived Stress","University Students","2026-05-05",{"date":72,"type":44},"2026-05-12",{"date":74,"type":23},"2026-05-15",{"date":76,"type":23},"2026-07-31",{"name":78,"class":51},"Harran University",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":87,"targetDuration":4,"studyType":24,"phases":89,"briefSummary":90,"conditions":91,"keywords":95,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":110},"100635966","act-based-group-therapy-and-mobile-application-intervention-for-emotional-eating-100635966","NCT07559552","ACT-Based Group Therapy and Mobile Application Intervention for Emotional Eating","The Effect of Acceptance and Commitment Therapy and a Mobile App on Emotional Eating, Emotion Regulation, and Psychological Flexibility in Overweight Individuals","ACT-EE","Inclusion Criteria:\n\n* Agreeing to participate in the study,\n* Being between 18-65 years of age,\n* Having a body mass index ≤ 25 (BMI ≤ 29.9),\n* Being able to read and write,\n* Having an iOS or Android smartphone,\n* Having internet access,\n* Having a home environment suitable for online sessions (having a computer\u002Fsmartphone, internet access at home, the patient being able to be alone in the room during the session, etc.),\n\nExclusion Criteria:\n\n* Having communication problems that would prevent the interview,\n* Having a diagnosis of a mental disorder, including an eating disorder, that would prevent participation in the study, or having concomitant serious medical conditions that could potentially jeopardize study participation.\n* Having undergone bariatric surgery. • Being on the waiting list for bariatric surgery.\n* Being pregnant, breastfeeding, or planning to become pregnant within the next 6 months.\n* Receiving therapy\u002Fcounseling for emotional eating and emotion regulation problems,\n* Using a mobile application for emotional eating and emotion regulation problems,",{"count":88,"type":23},78,[26],"This study aims to evaluate the effects of an Acceptance and Commitment Therapy (ACT)-based group therapy program, combined with an ACT-based mobile app, on emotional eating, emotion regulation, and psychological flexibility in overweight individuals. Emotional eating is a condition in which individuals frequently use eating behavior as a coping mechanism for negative emotions.\n\nParticipants will be randomly assigned to intervention groups receiving ACT-based group therapy, ACT-based group therapy combined with an ACT-based mobile app, or a control group. The intervention will last six weeks and will include structured group sessions as well as mobile-based exercises, reminders, and coping strategies.\n\nOutcome measures will include emotional eating, emotion regulation, and psychological flexibility. Assessments will be conducted at baseline, post-intervention, and during the follow-up phase. The findings of this study are expected to contribute to the development of accessible and effective interventions for emotional eating.",[92,93,94,30],"Emotional Eating","Emotion Regulation","Overweight",[96,92,93,30,97,98,99,94,100],"Acceptance and Commitment Therapy","Mobile Health (mHealth)","Mobile Application","Group Therapy","Digital Intervention","2026-04-22",{"date":103,"type":44},"2026-04-30",{"date":105,"type":23},"2026-06-15",{"date":107,"type":23},"2026-12-30",{"name":109,"class":51},"Saglik Bilimleri Universitesi",1,{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":24,"phases":119,"briefSummary":120,"conditions":121,"keywords":124,"overallStatus":129,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":110},"100626493","act-with-cf-self-help-toolkit-100626493","NCT07436351","ACT With CF Self-Help Toolkit","Inclusion Criteria:\n\n* 18 years or older\n* Existing diagnosis of cystic fibrosis\n* PHQ-9 score \\>4 or GAD-7 score \\>4\n\nExclusion Criteria:\n\n* History of suicide attempts or acute suicidal ideation on clinical assessment\n* Presence of psychotic disorder or symptoms\n* Presence of psychiatric disorders that interfere with participation in the study, judged by the study or treating clinician\n* Presence of other medical conditions that interfere with participation in the study, judged by the study or treating clinician",{"count":118,"type":23},60,[26],"Acceptance and Commitment Therapy (ACT) tailored to meet the needs of adults living with cystic fibrosis (ACT with CF) is a newer form of talk therapy that has been shown to reduce anxiety \\& depression and improve psychological flexibility, and value-based living. The investigators are now trying to find out whether a self-help version of this treatment (ACT with CF - Self Help Toolkit) is also effective in reducing anxiety and depression and improving psychological flexibility and value-based living in adults with CF.\n\nAdults with cystic fibrosis are at increased risk for anxiety and depression. This study examines whether a patient-facing therapy, ACT with CF - Self Help Toolkit can help to reduce anxiety and depression among adults with CF. This treatment can be accessed on the participant's smartphone.",[122,123,30],"Cystic Fibrosis (CF)","Depressive and Anxiety Disorders",[125,126,127,128],"cystic fibrosis","ACT","CF","chronic illness","RECRUITING","2026-02-27",{"date":132,"type":44},"2026-03-03",{"date":134,"type":44},"2026-01-20",{"date":136,"type":23},"2027-04",{"name":138,"class":51},"Thomas Jefferson University",{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":4,"eligibilityCriteria":145,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":146,"targetDuration":4,"studyType":24,"phases":148,"briefSummary":149,"conditions":150,"keywords":152,"overallStatus":129,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":110},"100619529","a-pilot-study-on-an-act-based-program-for-individuals-with-special-needs-and-their-caregivers-100619529","NCT07345806","A Pilot Study on an ACT-Based Program for Individuals With Special Needs and Their Caregivers","Promoting Wellbeing and Personal Values: A Pilot Study on a Group-Based Program for Individuals With Special Needs and Their Caregivers","Inclusion Criteria:\n\n* be at or older than 18 years old\n* understand Cantonese\n* read as well as write Chinese\n\nExclusion Criteria:\n\n* with borderline or greater intellectual deficits\n* weak language abilities\n* severe conditions related to mental, emotional, and\u002For behavioral functioning",{"count":147,"type":23},62,[26],"Parenting children with special health care needs can be stressful and weigh on the caregivers' mental health. For the individuals with special needs, the mismatch between their needs and the normative practice in the world around them can be frustrating and detrimental to their functioning. The demands and concerns to these families can be so real that it may not be sensible to examine the validity or helpfulness of the distressing thoughts or feelings but to promote psychological flexibility, which is a key to value-guided living. This pilot study explores the effects and feasibility of a group-based intervention for families of individuals with special health care needs.",[151,30],"Parenting Stress",[96,153,154],"Adults with SENs","Parents of Children with SENs","2026-01-07",{"date":157,"type":44},"2026-01-16",{"date":159,"type":44},"2025-10-14",{"date":161,"type":23},"2027-03-31",{"name":163,"class":51},"The University of Hong Kong",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":171,"targetDuration":4,"studyType":24,"phases":173,"briefSummary":174,"conditions":175,"keywords":4,"overallStatus":129,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":183,"completionDateStruct":184,"leadSponsor":186,"locationsCount":188},"100595544","acceptance-and-commitment-therapy-based-intervention-for-parents-of-a-child-with-medical-complexity-100595544","NCT07033832","Acceptance and Commitment Therapy-based Intervention for Parents of a Child With Medical Complexity","Acceptance and Commitment Therapy-based Intervention to Decrease Psychological Symptoms and Increase Psychological Flexibility for Parents of a Child With Medical Complexity: a Pilot Randomization-controlled Trial.","Inclusion Criteria:\n\n* parent of a child with medical complexity aged 1-18\n* able to communicate in Chinese and read Chinese\n* willing to participate in face-to-face activities\n\nExclusion Criteria:\n\n* a reported mental health disorder\n* engaging in other psychosocial educational programs related to stress reduction\n* inability to communicate in Cantonese",{"count":172,"type":23},30,[26],"A pilot randomized controlled trial of an Acceptance and Commitment Therapy-based intervention will be conducted to decrease psychological symptoms, while increase psychological flexibility for parents of a child with medical complexity during their difficulties.",[96,176,30,177,178,179],"Child With Medical Complexity","Randomised Controlled Trial","Depression, Anxiety","Parental Stress","2025-07-02",{"date":182,"type":44},"2025-07-08",{"date":180,"type":44},{"date":185,"type":23},"2026-06-30",{"name":187,"class":51},"The Hong Kong Polytechnic University",2]