[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"psychological-intervention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:psychological-intervention":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,45,84,112,143,173],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100564016","study-of-self-help-and-support-services-for-student-mental-health-in-tertiary-institutions-100564016",false,"NCT06623682","Study of Self-Help and Support Services for Student Mental Health in Tertiary Institutions","Efficacy, Cost-effectiveness and Implementation of an Integrated Self-help and Support Services for Student Mental Health in Tertiary Institutions: JCTH+ Pragmatic Cluster RCT","Inclusion Criteria:\n\n* 18 years old or above\n* Able to read Chinese or English\n* With internet connection and able to access the internet\n* With moderate-severe GAD-7 a\u002Fo moderate-severe PHQ-9\n* studying full-time at a tertiary education institution in Hong Kong\n\nExclusion Criteria:\n\n* not able to read and understand Chinese;\n* under 18 years old;\n* not able to access the Internet or use digital devices\n* without depressive symptoms or anxiety symptoms","ALL","18 Years",{"count":19,"type":20},1684,"ESTIMATED","INTERVENTIONAL",[23],"NA","This proposed study aims to evaluate the implementation of integrating the existing services in tertiary education institutions with the JCTH+ platform. The study aims to evaluate the efficacy of JCTH+ on students' mental health outcomes as compared to service as usual, and to assess the cost-utility of the platform to determine whether the benefits of implementing the platform justify the costs associated. It is hypothesized that participants who receive integrated self-help and support services will show (H1) a greater reduction in mental health symptoms, and (H2) better mental well-being compared with participants in the control condition, i.e. service-as-usual (SAU).",[26,27,28,29],"Mental Health","Mental Well-being","Psychological Intervention","Self-care",[31,26,27,29],"Online Psychological Intervention","RECRUITING","2026-03-22",{"date":35,"type":36},"2026-03-24","ACTUAL",{"date":38,"type":36},"2024-10-09",{"date":40,"type":20},"2026-08-29",{"name":42,"class":43},"Chinese University of Hong Kong","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":66,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":83},"100605106","optical-diagnosis-of-neoplasia-using-artificial-intelligence-100605106","NCT07158203","Optical Diagnosis of Neoplasia Using Artificial Intelligence","Assistance for Optical Diagnosis of Neoplasia Using Artificial Intelligence (FAIR Study)","FAIR","Endoscopists who meet the following inclusion\u002Fexclusion criteria Inclusion criteria\n\n* Endoscopists experienced with more than 100 colonoscopies. Exclusion criteria\n* Endoscopists who are involved in the development of the protocol of the present study.\n\nInclusion and exclusion criteria for the study videos. Inclusion criteria.\n\n* Videos with a duration of 15 seconds including both WL and NBI.\n* Videos with diminutive polyps with confirmed pathology. Exclusion criteria.\n* Videos with no clear image of the polyps.\n* Videos with more than one polyp on-screen.\n* Inflammatory bowel disease\n* Polyposis\n* Hereditary colorectal disease\n* Videos which CADx cannot provide sufficient number of outputs.",true,{"count":55,"type":20},70,[23],"Computer-aided diagnosis (CADx) for colonoscopy aims to enhance optical diagnosis but often underperforms when used alongside humans due to under-reliance on AI. Psychological interventions like cognitive forcing, such as delaying CADx suggestions, may improve human-AI interaction by fostering critical assessment. However, their impact on patient-important outcomes remains unexplored.\n\nThe investigators will conduct an ex-vivo randomized study with 70 endoscopists assessing 100 polyp videos (≤5 mm) using a CADx tool (GI Genius, Medtronic). Participants will be randomized to either:\n\n* Intervention group: CADx suggestions will be shown in the last 3 seconds of the 15 second polyp video.\n* Control group: CADx suggestions will be shown in real-time throughout the playback of the 15 second polyp video.\n\nThe primary endpoint is sensitivity for high-confidence neoplasia detection, with secondary endpoints assessing endoscopists' reliance on AI.\n\nCADx systems on the market function in various ways, such as real-time, delayed, or on-demand diagnosis. Our study aims to inform users and manufacturers whether cognitive forcing through delayed CADx suggestions enhances human-AI interaction, leading to improved clinical outcomes.",[59,60,61,62,63,64,65,28],"Polyps Colorectal","Colonoscopy","Optical Biopsy","Colorectal Cancer Control and Prevention","Colorectal Cancer Screening","Behavior Change","Psychological Factors",[67,68,69,70,71,72],"behaviour","optical biopsy","colonoscopy","CADx system","colorectal polyps","psychological intervention","NOT_YET_RECRUITING","2025-08-28",{"date":76,"type":36},"2025-09-05",{"date":78,"type":20},"2025-09",{"date":80,"type":20},"2025-12",{"name":82,"class":43},"Fundacin Biomedica Galicia Sur",2,{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":21,"phases":93,"briefSummary":94,"conditions":95,"keywords":98,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":110,"locationsCount":44},"100590799","digital-mindset-intervention-for-half-marathon-performance-100590799","NCT06972121","Digital Mindset Intervention for Half Marathon Performance","The Efficacy of a Digital Mindset Intervention to Improve Race Performance, Training Outcomes, and Recovery in Recreational Half Marathon Runners: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Be aged 18 years or older\n* Be registered to run (not walk) in a 2025 half marathon in New Zealand\n* Be running their 1st, 2nd, or 3rd half marathon\n* Be able to complete the half-marathon without physical assistance or aids\n* Be able to read and understand English\n* Have regular access to email or an internet-connected device\n\nExclusion Criteria:\n\n* Have completed more than 2 half marathons in the past\n* Are currently injured or unable to complete the race unassisted\n* Are unable to complete online questionnaires independently\n* Do not have access to a device capable of receiving digital content via app or email",{"count":92,"type":20},207,[23],"The goal of this randomized controlled trial is to test whether a brief digital mindset training program can improve performance among recreational runners training for a half marathon in New Zealand in 2025. The study will recruit healthy adult participants who are registered for an upcoming half-marathon event.\n\nThe study aims to answer two main questions:\n\n1. Does the mindset training program - designed to reframe common physical symptoms like fatigue or muscle soreness as signs of progress - help more runners complete the race and improve their official times, compared to standard training advice?\n2. Does it support better training (e.g., longer peak training weeks) and faster physical recovery after the race?\n\nResearchers will compare participants who receive the mindset training program to those who receive widely followed half-marathon training content and a group who receive no study content, to see whether the mindset training leads to better half-marathon performance and training outcomes.\n\nParticipants will:\n\n* Complete a brief online survey at the start of the study\n* Receive and engage with four pieces of digital content across nine weeks before the half-marathon race (if assigned to a training group)\n* Complete a follow-up survey after the half-marathon",[96,97,28],"Healthy","Exercise",[99,97,100,101,102,103],"Mindset","Physical Activity","Sports psychology","Marathon","Performance","2025-05-21",{"date":106,"type":36},"2025-05-28",{"date":108,"type":36},"2025-05-15",{"date":78,"type":20},{"name":111,"class":43},"University of Auckland, New Zealand",{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":120,"minAge":17,"maxAge":4,"enrollmentInfo":121,"targetDuration":4,"studyType":21,"phases":123,"briefSummary":124,"conditions":125,"keywords":129,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":44},"100590295","patient-education-strategy-for-breast-cancer-patients-during-perioperative-hospitalization-stage-100590295","NCT06965556","Patient Education Strategy for Breast Cancer Patients During Perioperative Hospitalization Stage","A Prospective Study to Evaluate the Clinical Significance of Medical Humanities-based Patient Education Strategy for Breast Cancer Patients During Perioperative Hospitalization Stage","PE-CAT","Inclusion Criteria:\n\n* More than 18 years old\n* Female\n* Patient with early-stage breast cancer with preoperative pathology confirming invasive breast carcinoma or ductal carcinoma in situ\n* No clinical or imaging evidence of distant metastasis\n* Patients to receive breast surgery during hospitalizaiton (including mastectomy, breast conserving therapy, reconstrucion, etc.)\n* Be able and willing to sign the Informed Consent Form (ICF)\n\nExclusion Criteria:\n\n* Patients with locally advanced breast cancer to receive neoadjuvant therapy\n* Patients currently participating in other clinical trials, which may have impact on the participation in this trial\n* Previous history of breast cancer (patients with ipsilateral recurrence after breast sparing surgery)","FEMALE",{"count":122,"type":20},1138,[23],"Introduction Breast cancer remains a leading global health concern, with significant psychological challenges during the perioperative period. Traditional patient education focuses on disease management but often neglects emotional and cognitive needs. Perioperative inpatients are relatively stable and have the time and mental space for deeper education and psychological support. This study evaluates the clinical significance of a medical humanities-based education strategy for breast cancer patients during hospitalization, aiming to enhance psychological resilience, treatment adherence, and quality of life.\n\nMethods and Analysis This prospective, non-randomized, open-label study will include female patients with early-stage breast cancer scheduled for surgery at Fudan University Shanghai Cancer Center. Participants will be allocated to two cohorts: practical education group and mental enhanced group. The primary endpoint is psychological assessment at hospital discharge, including anxiety (GAD-7), depression (PHQ-9), and sleep quality (ISI). Secondary endpoints include the proportion of patients opting for breast-conserving procedures, incidence of postoperative complications, long-term treatment adherence (MMAS-8), patients' disease-coping resilience (CD-RISC-10), and quality of life assessment (EORTC QLQ instruments) at 12-month follow-up. Data collection and statistical analysis will be conducted using validated instruments and software, with significance set at p ≤0.05.\n\nEthics and Dissemination Approved by the FUSCC ethics committee, all participants provide informed consent. Results will be disseminated through international conferences and peer-reviewed journals. The study adheres to ethical guidelines, ensuring data confidentiality via encrypted platforms. Authors declare no conflicts of interest, supported by Shanghai Municipal Science and Technology Innovation Action Plan (24DZ2303500). Findings aim to optimize perioperative education strategies, addressing psychological and informational needs of breast cancer patients.",[126,127,128,28],"Breast Carcinoma","Patient Education","Perioperative Care",[130,131,132,72,133],"breast carcinoma","patient education","educational comic","hospitalization","2025-05-11",{"date":136,"type":36},"2025-05-13",{"date":138,"type":20},"2025-06-01",{"date":140,"type":20},"2026-10-31",{"name":142,"class":43},"Fudan University",{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":147,"acronym":148,"eligibilityCriteria":149,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":150,"targetDuration":4,"studyType":21,"phases":152,"briefSummary":153,"conditions":154,"keywords":158,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":83},"100575057","emdr-for-fear-of-cancer-recurrence-in-patients-with-familial-melanoma-a-waiting-list-control-trial-100575057","NCT06767332","EMDR for Fear of Cancer Recurrence in Patients with Familial Melanoma: a Waiting List Control Trial","FAME","Inclusion Criteria:\n\n* a score of 16 or higher on the FCRI-NL-SF\n* 18 years or older\n* diagnosed with familial melanoma\n\nExclusion Criteria:\n\n* insufficient knowledge of the Dutch language.\n* acute psychiatric disease (psychosis, suicidal ideation)\n* variable dosis of anxiolytics",{"count":151,"type":20},30,[23],"High fear of cancer recurrence (FCR) impacts patient's quality of life (QoL) and is prevalent among patients with familial melanoma. The main objective is to investigate whether EMDR is effective in treating high FCR in patients with familial melanoma. The study design is a non-blinded, randomized waiting-list controlled trial. Patients aged 18 years or older with familial melanoma can be included. Patients with high FCR will receive a maximum of 4, 90 minutes, EMDR-sessions. The main study parameter is the decrease and level of FCR measured with the Cancer Worry Scale (CWS). The secondary study parameter is quality of life, measured with the EORTC.",[155,156,157,28],"Familial Melanoma","Fear of Cancer Recurrence","Eye Movement Desensitization and Reprocessing",[159,156,155,157,160,161,162,163],"EMDR","Psychological intervention","Anxiety","Psycho-oncology","FCR","2025-01-08",{"date":166,"type":36},"2025-01-09",{"date":168,"type":36},"2023-11-01",{"date":170,"type":20},"2025-12-31",{"name":172,"class":43},"Leiden University Medical Center",{"id":174,"slug":175,"hasResults":11,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":4,"eligibilityCriteria":179,"healthyVolunteers":53,"sex":16,"minAge":180,"maxAge":4,"enrollmentInfo":181,"targetDuration":4,"studyType":21,"phases":182,"briefSummary":183,"conditions":184,"keywords":4,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":44},"100556369","an-awareness-courage-and-love-intervention-to-help-chinese-older-adults-in-the-post-pandemic-era-100556369","NCT06524206","An Awareness, Courage, and Love Intervention to Help Chinese Older Adults in the Post-pandemic Era","An Awareness, Courage, and Love Intervention to Help Chinese Older Adults in the Post-pandemic Era: A Pilot Randomised Controlled Trial","Inclusion Criteria:\n\n1. aged 60 years or older and dwelling in the community;\n2. able to communicate in Cantonese;\n3. have access to the internet and videoconferencing devices such as a mobile phone;\n4. able to give informed consent to participate.\n\nExclusion Criteria:\n\n1. severe emotional distress based on PHQ-4 screening assessment or presenting an imminent suicidal risk;\n2. known history of autism, intellectual disability, schizophrenia-spectrum disorder, bipolar disorder, Parkinson's disease, or dementia\u002Fsignificant cognitive impairment;\n3. illiterate;\n4. difficulty in communication.","60 Years",{"count":55,"type":20},[23],"The purpose of this study is to explore the potential effectiveness of a one-session online Awareness, Courage, and Love intervention for reducing loneliness, depression and anxiety symptoms, and enhancing social connectedness and subjective well-being among older adults. the study also aims to estimate the effect sizes of the Awareness, Courage, and Love intervention.",[185,186,161,187,188,28,189],"Loneliness","Depression","Social Connectedness","Subjective Well-being","Older Adults","2024-07-26",{"date":192,"type":36},"2024-07-29",{"date":194,"type":20},"2024-08",{"date":196,"type":20},"2025-03",{"name":198,"class":43},"Caritas Institute of Higher Education"]