[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"psychological-well-being\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:psychological-well-being":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,35,0,25,[9,50,83,123,157,181,210,239,266,296,323,354,380,414,439,467,490,530,578,605,643,668,692,713,734],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100053351","the-effect-of-web-based-compassion-focused-structured-writing-programs-on-well-being-in-midwives-working-in-delivery-rooms-100053351",false,"NCT07699887","The Effect of Web-Based Compassion-Focused Structured Writing Programs on Well-Being in Midwives Working in Delivery Rooms","The Effect of Web-Based Compassion-Focused Writing Program and Reflective Writing Program on Psychological Outcomes in Midwives Working in Delivery Rooms: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Working as a midwife in a delivery room between November 1, 2025, and February 15, 2027\n2. Native Turkish speaker\n3. Female\n4. Aged between 18-65 years\n5. Having at least a bachelor's degree in midwifery\n6. Having at least three years of delivery room experience\n7. No diagnosed psychological or psychiatric disorder\n8. Having the technical infrastructure to use a web-based program\n9. Ability to use a smartphone, tablet, or computer\n10. Voluntary agreement to participate in the study\n\nExclusion Criteria:\n\n1. Not working in a delivery room during the specified dates\n2. Not a native Turkish speaker\n3. Under 18 or over 65 years of age\n4. Male\n5. Changing clinical unit during the study\n6. Not completing all five intervention sessions\n7. Working less than 40 hours per week in the delivery room due to leave or reassignment\n8. Voluntary withdrawal from the study at any stage",true,"FEMALE","18 Years","65 Years",{"count":22,"type":23},90,"ESTIMATED","INTERVENTIONAL",[26],"NA","This randomized controlled trial aims to compare the effects of a web-based compassion-focused writing program and a reflective writing program on psychological well-being, self-compassion, postpartum trauma-related stress symptoms, and post-traumatic growth in midwives working in delivery rooms.",[29,30,31],"Psychological Well-being","Secondary Traumatic Stress","Occupational Stress",[33,34,35,36,37],"Compassion-focused writing","Reflective writing","Midwife","Psychological well-being","Trauma","NOT_YET_RECRUITING","2026-07-07",{"date":41,"type":42},"2026-07-13","ACTUAL",{"date":44,"type":23},"2026-10-01",{"date":46,"type":23},"2027-02-15",{"name":48,"class":49},"Mersin University","OTHER",{"id":51,"slug":52,"hasResults":12,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":24,"phases":59,"briefSummary":60,"conditions":61,"keywords":66,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":82},"100641063","the-effect-of-pre-breastfeeding-breathing-exercises-on-maternal-anxiety-well-being-and-infant-stress-in-mothers-whose-infants-are-in-the-neonatal-intensive-care-unit-100641063","NCT07634445","The Effect of Pre-Breastfeeding Breathing Exercises on Maternal Anxiety, Well-being, and Infant Stress in Mothers Whose Infants Are in the Neonatal Intensive Care Unit","The Effect of Pre-Breastfeeding Breathing Exercises on Maternal Anxiety, Well-being, and Infant Stress in Mothers Whose Infants Are in the Neonatal Intensive Care Unit: A Radicalized Controlled Study","Inclusion Criteria:\n\n* Ability to communicate verbally,\n* Being 18 years of age or older,\n* Having a baby in the neonatal intensive care unit,\n* Breastfeeding.\n\nExclusion Criteria:\n\n* Having a psychiatric diagnosis according to medical records,\n* The mother having a definite health problem in the postpartum period that prevents breastfeeding (heart disease, etc.),\n* The study being terminated due to the newborn being discharged from the hospital,\n* Incomplete data collection.",{"count":58,"type":23},70,[26],"Aim: This study was conducted to examine the effects of breathing exercises on maternal anxiety, well-being, and infant stress.\n\nMaterials and Methods: The research was initiated in a hospital in eastern Turkey between November 2024 and November 2026, after obtaining ethical committee and institutional approvals. The study population consisted of mothers whose babies were hospitalized in the neonatal intensive care unit (NICU) of that hospital.The generally available G\\*Power 3.1.9.7 for Windows software was used to calculate the sample size. Similar literature studies were referenced when determining the sample size of the research (Shamsdanesh et al., 2023). Furthermore, after the research is completed, a post-hoc power analysis will be performed on the main dependent variable, maternal anxiety level (MAL), to determine the power of the study (approximately 35 experimental, 35 control). The aim of the research is to ensure that the resulting sample size has sufficient statistical power to reveal the effect being examined. The research data is collected using a Demographic Information Form, prepared by the researcher through a literature review, the State and Trait Anxiety Inventory, the Psychological Well-being Scale, and the Neonatal Stress Scale. Mothers perform this exercise three times a day for two days (days 1 and 2), under the supervision of a researcher. The four-square breathing exercise is a non-pharmacological pain reliever that has been shown to be beneficial in conditions other than pain. Each breathing exercise lasts 5-10 minutes. Mothers in the experimental group are given a questionnaire before the start of the study and after the exercise on days 1 and 2. Mothers in the control group are given only a questionnaire before the start of the study, at the end of day 1, and at the end of day 2. Mothers in the control group do not perform the four-square breathing exercise and receive routine hospital care. At the end of both days, mothers in the control group who wish to practice the breathing exercise are given the opportunity to do so.",[62,29,63,64,65],"Anxiety","Stress","Breath Exercise","Newborn",[67,68,69,70,71],"newborn","anxiety","stress","breathing exercise","psychological well-being","RECRUITING","2026-06-16",{"date":75,"type":42},"2026-06-18",{"date":77,"type":42},"2024-12-10",{"date":79,"type":23},"2026-11",{"name":81,"class":49},"Inonu University",1,{"id":84,"slug":85,"hasResults":12,"nctId":86,"briefTitle":87,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":17,"sex":90,"minAge":4,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":24,"phases":93,"briefSummary":94,"conditions":95,"keywords":104,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":82},"100634675","choice-and-autonomy-in-learning-mindfulness-for-pediatric-residents-100634675","NCT07542769","Choice and Autonomy in Learning Mindfulness for Pediatric Residents","CALM-PR","Inclusion Criteria:\n\n* Current categorical pediatrics residents at Northwestern University.\n* Preliminary pediatrics residents who intend to continue in pediatrics.\n* Willing and able to provide informed consent.\n\nExclusion Criteria:\n\n\\- None; all pediatric residents meeting inclusion criteria are eligible.","ALL",{"count":92,"type":23},42,[26],"This study is a pilot clinical trial designed to evaluate a flexible, online mindfulness program for pediatric residents. Medical training can be stressful, and although mindfulness programs are often offered to support well-being, many are either in-person or follow a fixed format that may not fit individual schedules or preferences. This study will test a digital mindfulness program called Wakeful, which allows participants to complete the course at their own pace. Participants will be randomly assigned to one of two groups: one group will be able to choose the length of their mindfulness program (3, 5, or 7 weeks), while the other group will be assigned a program length without a choice. The goal is to understand whether giving participants a choice improves how often they use the program, how satisfied they are with it, and whether they complete it. The main outcomes of this study focus on how participants interact with the program, including how many sessions they complete, how often they practice mindfulness on their own, and how useful and relevant they find the program. The study will also look at overall satisfaction and how many participants drop out before finishing. In addition, the study will explore whether participants report changes in mindfulness and compassion for others, although it is not designed to determine clinical improvements in mental health. By understanding how pediatric residents engage with different program formats, this study aims to inform the design of more flexible and user-centered digital wellness programs that better fit into demanding medical training environments.",[96,97,98,99,100,101,102,103],"Program Engagement","Treatment Adherence and Compliance","Mindfulness","Self-Compassion","Physician Burnout","Psychological Well-Being","Meditation","Meditation Training",[98,102,105,106,107,108,109,97,110,96,111,112,99,113],"Digital Health Intervention","Internet-Based Intervention","Physician Well-Being","Graduate Medical Education","Pediatric Residency","Patient Acceptance of Health Care","User Engagement","Pilot Projects","Compassion","2026-05-21",{"date":116,"type":42},"2026-05-26",{"date":118,"type":42},"2026-04-13",{"date":120,"type":23},"2027-05-01",{"name":122,"class":49},"Northwestern University",{"id":124,"slug":125,"hasResults":12,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":129,"eligibilityCriteria":130,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":131,"targetDuration":4,"studyType":24,"phases":133,"briefSummary":135,"conditions":136,"keywords":140,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":82},"100634944","phase-1-yoga-for-black-and-brown-women-who-have-experienced-abuse-from-an-intimate-partner-100634944","NCT07546266","Yoga for Black and Brown Women Who Have Experienced Abuse From an Intimate Partner","A Culturally Tailored, Trauma-Informed Yoga Program for Women of Color Who Have Experienced Intimate Partner Violence","SOAR","Inclusion Criteria:\n\n* Self-identify as a Woman of Color (WOC).\n* Lifetime experience of intimate partner violence (IPV)\n* Age 18 years or older.\n* Willingness to complete study procedures",{"count":132,"type":23},40,[134],"PHASE1","The goal of this clinical trial is to determine if a culturally tailored and trauma-informed yoga (CT-TIY) program improves the overall well-being of Black and Brown women who have experienced IPV. The main questions it aims to answer are:\n\n* What is the feasibility, acceptability, and safety of delivering the CT-TIY program?\n* Do participants randomized to the CT-TIY program experience increases in our primary outcome of psychological well-being relative to women randomized to an enhanced care-as-usual control condition?\n* Do participants randomized to the CT-TIY program experience improvements in our secondary outcomes of empowerment, resilience, health-related quality of life, collective self-esteem, and culturally specific coping relative to participants randomized to an enhanced care-as-usual control condition? Researchers will compare CT-TIY to enhanced care-as-usual to see if CT-TIY to determine the feasibility, acceptability, safety, as well as initial efficacy of the yoga program.\n\nParticipants randomized to the CT-TIY program will:\n\n* Have 15 weeks to complete a target of 10 CT-TIY yoga classes\n* Provide feedback on the CT-TIY program after each class they attend\n* Complete assessments at Baseline, after completing the CT-TIY program (week 16), as well as 3-months (week 27) after completing the CT-TIY program\n* Complete an exit interview where they provide feedback on their experiences in the yoga program\n\nParticipants randomized to the enhanced care-as-usual control condition will:\n\n* Receive a referral to a domestic violence provider and the Futures without Violence General Health Safety Card, designed to help women recognize how their relationship impacts their health and the lives of their children, and provides information on safety planning and hotlines for support.\n* Complete assessments at Baseline, week 16, and week 27 of the study.",[137,138,139],"Intimate Partner Violence (IPV)","Psychological Well Being","Psychological Trauma, Historical",[141,142,143,144,145,146,147],"women of color","minority health","yoga","trauma informed","sister circles","domestic violence","intimate partner violence","2026-04-22",{"date":150,"type":42},"2026-04-28",{"date":152,"type":23},"2026-05-15",{"date":154,"type":23},"2027-12-31",{"name":156,"class":49},"The University of Akron",{"id":158,"slug":159,"hasResults":12,"nctId":160,"briefTitle":161,"officialTitle":162,"acronym":4,"eligibilityCriteria":163,"healthyVolunteers":17,"sex":164,"minAge":165,"maxAge":4,"enrollmentInfo":166,"targetDuration":4,"studyType":24,"phases":168,"briefSummary":169,"conditions":170,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":4},"100635504","the-effect-of-a-breathing-and-progressive-muscle-relaxation-program-100635504","NCT07553546","THE EFFECT OF A BREATHING AND PROGRESSIVE MUSCLE RELAXATION PROGRAM","THE EFFECT OF A BREATHING AND PROGRESSIVE MUSCLE RELAXATION PROGRAM ON SLEEP QUALITY AND PSYCHOLOGICAL WELL_BEING IN UNIVERSITY ATHLETES: A NON- RANDOMIZED CONTROLLED INTERVENTION STUDY","Inclusion Criteria:\n\n* Being between the ages of 18 and 24\n* Being male\n* Currently actively participating in an American football team\n* Volunteering to participate in the study\n\nExclusion Criteria:\n\n* Use of antiepileptic, antipsychotic, antidepressant, hormonal, or hypnotic medications Not volunteering to participate in the study","MALE","18 Months",{"count":167,"type":23},60,[26],"This non-randomized controlled study evaluates a 10-week breathing and myofascial release program in university athletes. The intervention group receives structured training, while the control group receives only an informational brochure.",[171,172,29],"Breathing Exercises","PROGRESSIVE MUSCLE RELAXATION EXERCISES","2026-04-20",{"date":150,"type":42},{"date":176,"type":23},"2026-05-01",{"date":178,"type":23},"2026-07-15",{"name":180,"class":49},"Marmara University",{"id":182,"slug":183,"hasResults":12,"nctId":184,"briefTitle":185,"officialTitle":186,"acronym":4,"eligibilityCriteria":187,"healthyVolunteers":17,"sex":90,"minAge":188,"maxAge":189,"enrollmentInfo":190,"targetDuration":4,"studyType":24,"phases":192,"briefSummary":193,"conditions":194,"keywords":196,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":206,"leadSponsor":208,"locationsCount":82},"100635322","mandala-activity-for-anxiety-and-emotional-and-psychological-well-being-in-adolescents-with-siblings-with-special-needs-100635322","NCT07551180","Mandala Activity for Anxiety and Emotional and Psychological Well-Being in Adolescents With Siblings With Special Needs","Effect of a Mandala Activity on Anxiety Levels and Emotional and Psychological Well-Being in Adolescents Who Have Siblings With Special Needs: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adolescents within the predefined study age range\n* Having a sibling with special needs\n* Ability to communicate in Turkish\n* Willingness to participate in the study\n* Written informed consent from a parent or legal guardian and assent from the adolescent\n* Availability to attend the planned intervention and assessment sessions\n\nExclusion Criteria:\n\n* Having any physical, cognitive, or communication problem that would prevent participation in the mandala activity program or completion of the measurement tools\n* Not attending the planned intervention sessions\n* Withdrawal of consent\u002Fassent during the study period","10 Years","19 Years",{"count":191,"type":23},64,[26],"The purpose of this randomized controlled trial is to evaluate whether a structured mandala activity program can reduce anxiety and improve emotional and psychological well-being in adolescents who have a sibling with special needs. Adolescents in this group may experience emotional difficulties because of the demands and challenges associated with having a sibling who requires special care and support. However, supportive and accessible interventions for these adolescents are limited.\n\nIn this study, eligible participants will be randomly assigned to either an intervention group or a control group. The intervention group will participate in a structured mandala activity program, while the control group will not receive this program during the study period. Anxiety and emotional and psychological well-being will be assessed before and after the intervention using standardized measurement tools.\n\nThe main question of this study is whether participation in the mandala activity program leads to better mental well-being outcomes compared with the control group. The findings may help determine whether mandala-based activities can be used as a simple, supportive, and non-pharmacological approach for adolescents who have a sibling with special needs.",[62,195,29],"Emotional Well-being",[197,198,199,200,101,62,201],"Adolescents","Siblings with Special Needs","Mandala Activity","Emotional Well-Being","Randomized Controlled Trial",{"date":203,"type":42},"2026-04-24",{"date":205,"type":23},"2026-05-02",{"date":207,"type":23},"2026-06-30",{"name":209,"class":49},"Akdeniz University",{"id":211,"slug":212,"hasResults":12,"nctId":213,"briefTitle":214,"officialTitle":215,"acronym":4,"eligibilityCriteria":216,"healthyVolunteers":17,"sex":90,"minAge":19,"maxAge":217,"enrollmentInfo":218,"targetDuration":4,"studyType":24,"phases":219,"briefSummary":220,"conditions":221,"keywords":224,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":231,"startDateStruct":233,"completionDateStruct":235,"leadSponsor":237,"locationsCount":82},"100634079","the-effect-of-mandala-art-therapy-psychological-resilience-coping-with-cancer-colorectal-cancer-surgery-100634079","NCT07535021","The Effect of Mandala Art Therapy, Psychological Resilience, Coping With Cancer, Colorectal Cancer Surgery","The Effect of Mandala Art Therapy on Psychological Resilience and Coping With Cancer in Patients Undergoing Colorectal Cancer Surgery: a Prospective Randomized Controlled Study.","Inclusion Criteria:\n\n* To communicate,\n* Aged 18 or older,\n* Agreed to participate\n* Scheduled for colorectal cancer surgery.\n* No physical disability of the upper extremities,\n* no visual problems,\n* no history of psychotic drug use,\n* pain intensity and fatigue level ≤3 points according to VAS-10 before MST application,\n* will be hospitalized for 3 days postoperatively,\n\nExclusion Criteria:\n\n* Over 74 years old,\n* has not completed mandala art therapy application,\n* is not compliant with the application,\n* has a history of previous psychiatric diagnosis.","74 Years",{"count":58,"type":23},[26],"The aim of this study is to evaluate the effects of mandala art therapy on psychological resilience and coping with cancer in patients undergoing colorectal cancer surgery.\n\nThis study was conducted as a randomized controlled trial with a pre-test-post-test design, including intervention and control groups. The study will be conducted between January 2026 and December 2026 with patients undergoing colorectal cancer surgery. The G.power 3.1.9.7 program was used for sample size calculation. The sample size was determined as 28 individuals in each group, considering equal sample sizes in the experimental and control groups, a 95% confidence interval (type I error 5%), and statistical power of 80% (type II error 20%) with an effect size of d=0.50. However, considering a possible 20% data loss, 35 individuals will be included in each group, resulting in a total sample size of 70 individuals.\n\nSample selection will be made using sequential sampling according to inclusion criteria. Patients will then be randomly assigned to the experimental group (A) and the control group (B) using block randomization (four-block). First, 15 blocks of four, such as AABB, ABAB, ABBA, BBAA, BABA, BAAB, etc., will be prepared by the researcher and statistician. Individuals will then be divided into two groups according to the prepared list; this process will be repeated continuously until the sample size is complete.\n\nThree data collection forms were used. SPSS 22.00 software package was used for data analysis. Skewness and kurtosis analyses were performed to determine the normality of the data distribution. Frequency (n) and percentage (%) distributions were calculated to determine the sociodemographic and clinical characteristics of the participants. Independent samples t-test was used to determine the mean differences between two independent groups, dependent samples t-test was used to compare pre- and post-intervention measurements, and repeated measures one-way analysis of variance (ANOVA) was used. Cohen's d effect size was calculated to evaluate the significance of the difference between groups in terms of the intervention. The statistical significance level was accepted as p\\\u003C0.05.",[222,223,101],"Colorectal Cancer","Coping, Cognitive",[225,226,227,228,229],"colorectal cancer","cope with cancer","psychological resilience","mandala art therapy","nursing care","2026-04-10",{"date":232,"type":42},"2026-04-16",{"date":234,"type":42},"2026-01-01",{"date":236,"type":23},"2026-12",{"name":238,"class":49},"Cumhuriyet University",{"id":240,"slug":241,"hasResults":12,"nctId":242,"briefTitle":243,"officialTitle":244,"acronym":4,"eligibilityCriteria":245,"healthyVolunteers":17,"sex":90,"minAge":19,"maxAge":246,"enrollmentInfo":247,"targetDuration":4,"studyType":24,"phases":249,"briefSummary":250,"conditions":251,"keywords":253,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":257,"lastUpdatePostDateStruct":258,"startDateStruct":260,"completionDateStruct":262,"leadSponsor":264,"locationsCount":82},"100543863","the-impacts-of-mindfulness-on-psychological-wellbeing-among-nursing-students-100543863","NCT06361394","The Impacts of Mindfulness on Psychological Wellbeing Among Nursing Students","The Impacts of Mindfulness on Psychological Wellbeing and Nursing Competencies Among Nursing Students","Inclusion Criteria:\n\n* Nursing students enrolled at the participating university\n* Aged 18 years or older\n* Willing to participate in the study\n* Able to provide written informed consent\n* Enrolled in the elective course \"Mindfulness and Happiness\" for assignment to the experimental group, or not enrolled in the course for assignment to the comparison group\n\nExclusion Criteria:\n\n* Younger than 18 years\n* Unwilling or unable to provide informed consent","50 Years",{"count":248,"type":23},240,[26],"The aims of this study are to develop a mindfulness-based elective course for nursing students and to evaluate its effects on psychological well-being, including mindfulness, depression, anxiety, stress, and problematic internet use, empathy, among nursing students.",[29,98,252],"Problematic Internet Use",[254,63,62,255,98,256],"Empathy","Nursing students","Problematic internet use","2026-03-16",{"date":259,"type":42},"2026-03-18",{"date":261,"type":42},"2025-02-10",{"date":263,"type":23},"2026-12-31",{"name":265,"class":49},"Chang Gung University of Science and Technology",{"id":267,"slug":268,"hasResults":12,"nctId":269,"briefTitle":270,"officialTitle":271,"acronym":272,"eligibilityCriteria":273,"healthyVolunteers":17,"sex":90,"minAge":19,"maxAge":4,"enrollmentInfo":274,"targetDuration":4,"studyType":24,"phases":276,"briefSummary":277,"conditions":278,"keywords":281,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":286,"lastUpdatePostDateStruct":287,"startDateStruct":289,"completionDateStruct":291,"leadSponsor":293,"locationsCount":295},"100562675","self-help-plus-for-distress-in-university-students-100562675","NCT06606249","Self-Help Plus for Distress in University Students","Randomized Trial of a Brief, Transdiagnostic, Guided Self-help Intervention for University Students Who Are Behind on Their Coursework and Experience Distress","SSH+","Inclusion Criteria:\n\n* University students across all years of higher education (i.e., bachelor and masters), enrolled in any degree course, starting from the second semester of the 1st year\n* Currently behind coursework by at least 3 exams, including: exams failed, for which the obtained grade was not confirmed by the student (i.e., confirming the grade is mandatory in the Italian academic system), or postponed (i.e., not taken in the regularly scheduled period).\n* Experience significant distress as assessed by the Kessler psychological distress scale (K-10) ≥ 16.\n\nExclusion Criteria:\n\n• None",{"count":275,"type":23},210,[26],"Prrospective, multi-center, randomized controlled trial of a brief, transdiagnostic, guided self-help intervention (Self-Help Plus) for university students who experience significant distress and are behind on their coursework. The intervention will be tested in terms of efficacy and feasibility for outcomes related to distress, anxiety, depression and well-being, assessed immediately after the intervention and at 3-months follow-up.",[279,101,280,62],"Psychological Distress","Depression",[282,283,284,285],"prevention","university students","academic deceit","emotion regulation","2026-03-11",{"date":288,"type":42},"2026-03-13",{"date":290,"type":42},"2025-03-10",{"date":292,"type":23},"2027-01",{"name":294,"class":49},"University of Padova",3,{"id":297,"slug":298,"hasResults":12,"nctId":299,"briefTitle":300,"officialTitle":301,"acronym":4,"eligibilityCriteria":302,"healthyVolunteers":17,"sex":90,"minAge":19,"maxAge":4,"enrollmentInfo":303,"targetDuration":4,"studyType":24,"phases":305,"briefSummary":306,"conditions":307,"keywords":309,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":314,"lastUpdatePostDateStruct":315,"startDateStruct":317,"completionDateStruct":319,"leadSponsor":321,"locationsCount":4},"100628773","perma-based-mobile-psychological-intervention-with-and-without-telephone-support-for-university-students-100628773","NCT07466004","PERMA-Based Mobile Psychological Intervention With and Without Telephone Support for University Students","Efficacy of a Positive Psychology-Based Psychological Intervention Grounded in the PERMA Model Delivered Via Smartphone App, With and Without Telephone Multiconference Support, for the Promotion of Psychological Well-Being in University Students","Inclusion Criteria:\n\n* Being an actively enrolled university student at the University of Santiago de Compostela (USC)\n* Having access to a smartphone with an internet connection.\n\nExclusion Criteria:\n\n* Having a current diagnosis of severe psychiatric disorder, including major depressive disorder with psychotic features, bipolar disorder, schizophrenia, severe cognitive impairment, dissociative disorders, or active substance dependence\n* Having started psychological or psychopharmacological treatment within the two months prior to the study or participating in another mental health-related study\n* Having insufficient proficiency in Spanish, or presenting sensory, cognitive, or physical impairments that would prevent engagement with the intervention\n* Planning to move out of Galicia within the next 12 months.",{"count":304,"type":23},177,[26],"University students face increasing academic and psychosocial demands that place them at risk of reduced psychological well-being. Positive psychology interventions have demonstrated efficacy in promoting mental health; however, few are grounded explicitly in Seligman's PERMA model and adherence to digital interventions remains limited. This randomized controlled trial aims to evaluate the efficacy of a brief PERMA-based psychological intervention delivered via a smartphone application, with and without supplementary telephone multiconference support, compared to a waiting list control group. The intervention consists of five weekly modules targeting Positive Emotion, Engagement, Relationships, Meaning, and Accomplishment. Assessments will be conducted at baseline, post-intervention, and at six-month follow-up.",[138,308],"Mental Health Promotion",[310,311,312,313],"PERMA model","University students","Mobile intervention","Randomized controlled trial","2026-03-06",{"date":316,"type":42},"2026-03-12",{"date":318,"type":23},"2026-09-01",{"date":320,"type":23},"2029-08-31",{"name":322,"class":49},"University of Santiago de Compostela",{"id":324,"slug":325,"hasResults":12,"nctId":326,"briefTitle":327,"officialTitle":328,"acronym":329,"eligibilityCriteria":330,"healthyVolunteers":17,"sex":90,"minAge":19,"maxAge":4,"enrollmentInfo":331,"targetDuration":333,"studyType":334,"phases":4,"briefSummary":335,"conditions":336,"keywords":337,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":345,"lastUpdatePostDateStruct":346,"startDateStruct":348,"completionDateStruct":349,"leadSponsor":351,"locationsCount":82},"100626294","test-retest-reliability-of-the-wb6dim-digital-well-being-tool-a-3-day-interval-study-100626294","NCT07433764","Test-Retest Reliability of the WB6Dim Digital Well-Being Tool: A 3-Day Interval Study","Psychometric Validation of Test-Retest Reliability of the WB6Dim Digital Self-Assessment Tool for Well-Being Using a 3-Day Interval Protocol and Contamination Control","WB6Dim-TRT","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Able to read and understand French\n* Access to an internet-connected device\n* Willing to complete the WB6Dim questionnaire at T1 and T2\n* Consent to anonymous data collection for research purposes\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Unable to read or understand French",{"count":332,"type":23},500,"9 Weeks","OBSERVATIONAL","This study aims to establish the test-retest reliability of the WB6Dim digital self-assessment tool across its eight well-being dimensions, using a 3-day interval protocol designed to minimize the probability of genuine well-being changes between assessments.\n\nParticipants complete the 28-item WB6Dim questionnaire at baseline (T1) and again 3 days later (T2). A single contamination control question at T2 identifies participants who experienced a significant life event during the interval; these pairs are excluded from primary ICC analyses and retained for exploratory analyses.\n\nAn optional third assessment at 9 weeks (T3) provides preliminary exploratory data on sensitivity to change following access to a well-being program. T3 is not part of the primary design.",[138],[338,339,340,341,342,343,344],"well-being","Test-retest reliability","Intraclass correlation","Digital self-assessment","WB6Dim","Psychometric validation","Workplace well-being","2026-02-19",{"date":347,"type":42},"2026-02-25",{"date":345,"type":42},{"date":350,"type":23},"2026-05-09",{"name":352,"class":353},"Clover Link","INDUSTRY",{"id":355,"slug":356,"hasResults":12,"nctId":357,"briefTitle":358,"officialTitle":359,"acronym":4,"eligibilityCriteria":360,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":361,"enrollmentInfo":362,"targetDuration":4,"studyType":24,"phases":363,"briefSummary":364,"conditions":365,"keywords":368,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":372,"lastUpdatePostDateStruct":373,"startDateStruct":375,"completionDateStruct":377,"leadSponsor":378,"locationsCount":82},"100621369","effects-of-mobilization-and-caffeine-after-cesarean-100621369","NCT07369726","Effects of Mobilization and Caffeine After Cesarean","The Effect of Early Post-Cesarean Mobilization and Caffeine Consumption on Bowel Motility, Pain, and Psychological Well-being: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Being between 18 and 35 years of age,\n2. Women who underwent cesarean delivery under spinal anesthesia,\n3. Having a post-cesarean pain level of 4 or higher,\n4. Being able to understand and write Turkish and communicate effectively with researchers.\n\nExclusion Criteria:\n\n1. Women who underwent emergency cesarean delivery,\n2. Those with pregnancy complications (preeclampsia, placenta previa, etc.),\n3. Those with a history of chronic gastrointestinal disease (e.g., irritable bowel syndrome, Crohn's disease, ulcerative colitis),\n4. Those with sensitivity or allergy to caffeine,\n5. Those with a history of chronic pain syndrome or dependence on analgesics,\n6. Regular coffee drinkers (≥2 cups per day),\n7. Intraoperative complications such as bowel or bladder injury,\n\ni) Those who cannot comply with the study protocol or complete the follow-up process.\n\nRemoval Criteria:\n\n1. Participants are excluded from the study under the following conditions:\n2. During surgery If complications occur (e.g., bladder or bowel injury, excessive bleeding),\n3. Postoperative complications requiring admission to the intensive care unit (ICU) for the mother or newborn,\n4. Development of severe postoperative nausea, vomiting, or intolerance to oral intake,\n5. Inability to consume or refusal to consume coffee according to the study protocol,\n6. Withdrawal of consent by the participant at any point during the study,\n7. Failure to comply with surgical procedures or loss of follow-up,\n8. Development of medical conditions during follow-up that may affect study results (e.g., acute infections, neurological disorders).","35 Years",{"count":167,"type":23},[26],"This study Maims to assess bowel motility, pain and psychological well-being in women in the post-cesarean period by mobilizing them early and encouraging them to consume coffee.",[366,367,101],"Gastrointestinal Motility","Postoperative Pain",[369,370,101,371],"gastrointestinal motility","postoperatif pain","Early Ambulation","2026-02-05",{"date":374,"type":42},"2026-02-09",{"date":376,"type":42},"2025-11-25",{"date":176,"type":23},{"name":379,"class":49},"KTO Karatay University",{"id":381,"slug":382,"hasResults":12,"nctId":383,"briefTitle":384,"officialTitle":385,"acronym":386,"eligibilityCriteria":387,"healthyVolunteers":12,"sex":90,"minAge":19,"maxAge":4,"enrollmentInfo":388,"targetDuration":389,"studyType":334,"phases":4,"briefSummary":390,"conditions":391,"keywords":396,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":406,"lastUpdatePostDateStruct":407,"startDateStruct":409,"completionDateStruct":411,"leadSponsor":412,"locationsCount":82},"100611495","psychological-well-being-depression-and-health-related-quality-of-life-in-adults-with-type-2-diabetes-a-cross-sectional-study-100611495","NCT07241325","Psychological Well-Being, Depression, and Health-Related Quality of Life in Adults With Type 2 Diabetes: A Cross-Sectional Study","A Cross-Sectional Observational Study to Evaluate Psychological Well-Being, Depression, and Health-Related Quality of Life and Their Demographic and Clinical Correlates in Adults With Type 2 Diabetes Attending an Outpatient Metabolic Clinic","PWDQ-T2D","Inclusion Criteria:\n\n1. Adults aged 18 years or older with full legal capacity.\n2. Clinically diagnosed with Type 2 Diabetes Mellitus and receiving ongoing outpatient care.\n3. Able to read and understand Chinese questionnaires and complete self-administered forms.\n4. Understand the study purpose and procedures and provide written informed consent.\n\nExclusion Criteria:\n\n1. Presence of major psychiatric disorders (e.g., schizophrenia, bipolar disorder, major depressive disorder).\n2. Moderate to severe cognitive impairment or dementia, as assessed by the clinical physician, making it impossible to complete the questionnaires.\n3. Currently experiencing acute diabetic complications (e.g., diabetic ketoacidosis, hyperosmolar hyperglycemic state) or hospitalization.\n4. Severe language or other communication barriers preventing expression of consent or understanding of study content.",{"count":332,"type":23},"1 Day","This prospective cross-sectional observational study aims to explore the relationships among psychological well-being, depression, and quality of life in patients with type 2 diabetes attending the outpatient metabolic clinic at National Taiwan University Hospital. The study will collect data using standardized instruments, including the EQ-5D Health-Related Quality of Life Questionnaire, the PHQ-9 Depression Scale, and the Shalom Scale of Psychological Well-Being, along with demographic and clinical variables such as age, sex, education, body mass index, HbA1c, disease duration, and psychosocial support indicators. Descriptive statistics, Pearson correlation analyses, ANOVA, and multiple linear regression modeling will be performed to identify factors associated with psychological well-being. The findings are expected to provide evidence-based insights to inform tailored interventions and improve the mental health and quality of life of patients with type 2 diabetes.",[392,393,394,29,395],"Type 2 Diabetes Mellitus (T2DM)","Health-related Quality of Life","Depressive Symptoms","Spiritual Well-being",[397,101,280,398,399,400,401,402,403,404,405],"Type 2 Diabetes Mellitus","PHQ-9","EQ-5D-5L","Shalom Scale","Spiritual Well-Being","Psychosocial Support","Cross-Sectional","Observational","Taiwan","2026-01-26",{"date":408,"type":42},"2026-01-28",{"date":410,"type":42},"2025-09-19",{"date":44,"type":23},{"name":413,"class":49},"National Taiwan University Hospital",{"id":415,"slug":416,"hasResults":12,"nctId":417,"briefTitle":418,"officialTitle":418,"acronym":4,"eligibilityCriteria":419,"healthyVolunteers":17,"sex":90,"minAge":19,"maxAge":420,"enrollmentInfo":421,"targetDuration":4,"studyType":24,"phases":423,"briefSummary":424,"conditions":425,"keywords":427,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":430,"lastUpdatePostDateStruct":431,"startDateStruct":433,"completionDateStruct":435,"leadSponsor":437,"locationsCount":82},"100619591","development-of-the-online-mindfulness-based-intervention-mind-space-application-for-thai-university-students-phase-ii-100619591","NCT07346612","Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II","Inclusion Criteria: the researchers will specifically recruit volunteers who:\n\n1. are current studying in years 1-4 of undergraduate programs\n2. can read, speak, and write in Thai\n3. be risk of the mental health problem (score higher than 6 on the General Health Questionnaire (GHQ-28))\n4. have no history of learning disorders (ADHD, other specific learning disorders)\n5. have no psychiatric disorders (schizophrenia, adjustment disorders, delusion disorders, and substance use disorders)\n6. have no meditation experience within the past 6 months\n\nExclusion Criteria: the researchers will exclude the volunteers who;\n\n1. have a limitation for mindful movement (hearing loss, blindness, and movement limitations)\n2. uncomfortable or feel distress and cannot participate in each mindfulness-based intervention session","25 Years",{"count":422,"type":23},450,[26],"Development of the online mindfulness-based intervention (MFU-mindful Application for Thai university students: Phase II\n\nObjectives:\n\nPhase I: (October 2025 to September 2026)\n\n1. To develop the mindfulness-based intervention (Mind Space application) for Thai university students.\n2. To test the feasibility of the mindfulness-based intervention (Mind space Application) for Thai university students.\n3. To determine the effect size of mindfulness-based intervention (Mind space Application) on mental health outcomes for Thai university students: A pilot study. Phase II: (October 2026 to December 2026)\n\n1\\. To examine the effects of mindfulness-base intervention (Mindspace Application) on mental health outcomes for Thai university students For this research project, investigators will develop the mindfulness-based intervention (Mindspace application) based on mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) by encouraging participants to pay attention to their present thoughts, emotions, feelings, and behaviors without judgment. This attention will help them learn the relationship between their thoughts, emotions, and behaviors and their mental health outcomes (mindfulness, stress, anxiety, and depression), though. mindfulness practice (body scan, sitting meditation, and mindful movement) using an online application). Furthermore, investigators will teach participants how to shape their thoughts and manage their wandering minds and negative and irritable thoughts. Finally, participants will learn how to become an individual with reasonable flexibility and positive thoughts.\n\nSettings: the researchers plan to conduct the program in three universities in Northern Thailand.\n\nPopulation and sample:\n\nPopulation: Thai university students who are between years 1 and 4 (undergraduate).\n\nSample:\n\nPhase I: Mae Fah Luang University, Phayao University, and Utraradit University students who are studying during the Fall semester, year 2026. Investigators will specifically recruit volunteers who:\n\nInclusion criteria:\n\n1. are current studying in years 1-4 of undergraduate programs\n2. can read, speak, and write in Thai\n3. be risk of the mental health problem (score higher than 6 on the General Health Questionnaire (GHQ-28)\n4. have no history of learning disorders (ADHD, other specific learning disorders)\n5. have no psychiatric disorders (schizophrenia, adjustment disorders, delusion disorders, and substance use disorders)\n6. have no meditation experience within the past 6 months\n\nExclusion criteria:\n\n1. have a limitation for mindful movement (hearing loss, blindness, and movement limitations)\n2. They may feel uncomfortable or distressed and may not be able to participate in each mindfulness-based intervention session.\n\nConceptual frameworks. For this research project, the investigators will develop and refine an online mindfulness-based intervention, the Mind Space Application, grounded in the principles of Mindfulness-Based Stress Reduction (MBSR; Kabat-Zinn, 2003) and Mindfulness-Based Cognitive Therapy (MBCT; Segal et al., 2002). The program is designed to cultivate nonjudgmental awareness of thoughts, feelings, emotions, and behaviors among university students (Kabat-Zinn, 2003). In addition, it aims to enhance participants' understanding of the interrelationships among cognitions, emotions, affective experiences, and behaviors that contribute to psychological distress, including stress, anxiety, and depressive symptoms.\n\nThe intervention incorporates core mindfulness practices delivered via an online application, including body scan exercises, sitting meditation, and mindfulness-based movement for relaxation. Furthermore, participants will be guided to develop cognitive awareness and adaptive responses to internal and external stressors, with particular emphasis on recognizing and managing automatic thoughts (wandering mind), negative thoughts, and irrational or maladaptive cognitions. Through this process, participants are encouraged to cultivate more rational, flexible, and positive thinking patterns.\n\nThe researchers anticipate that this program will enhance mindfulness skills and, in turn, contribute to reductions in stress, anxiety, and depressive symptoms among the study participants.\n\nThe effectiveness of the Mind Space application will be examined across both short-term and long-term periods. Short-term effects will be assessed at baseline and immediately post-intervention (8 weeks), while long-term effectiveness will be evaluated at a 6-month follow-up. Outcomes in the intervention group will be compared with those in a control group. The primary outcome variables include mental health indicators-stress, anxiety, and depressive symptoms-as well as levels of mindfulness among Thai university students. Data will be analyzed using a one-way repeated-measures multivariate analysis of variance (MANOVA).",[426,138,98],"University Students",[283,428,429],"depression","psychological well being","2026-01-07",{"date":432,"type":42},"2026-01-16",{"date":434,"type":23},"2026-02-01",{"date":436,"type":23},"2027-09-30",{"name":438,"class":49},"Mae Fah Luang University",{"id":440,"slug":441,"hasResults":12,"nctId":442,"briefTitle":443,"officialTitle":444,"acronym":4,"eligibilityCriteria":445,"healthyVolunteers":17,"sex":90,"minAge":4,"maxAge":4,"enrollmentInfo":446,"targetDuration":4,"studyType":24,"phases":448,"briefSummary":449,"conditions":450,"keywords":453,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":458,"lastUpdatePostDateStruct":459,"startDateStruct":461,"completionDateStruct":463,"leadSponsor":465,"locationsCount":82},"100618867","the-effectiveness-of-three-good-things-on-gratitude-and-psychological-well-being-among-nursing-students-100618867","NCT07337200","The Effectiveness of Three Good Things on Gratitude and Psychological Well-being Among Nursing Students","The Effectiveness of Daily Three Good Thing Intervention on Gratitude and Psychological Well-being Among Indonesian Nursing Students: Solomon Four-Group Design","Inclusion Criteria:\n\n* Active first- and second-year students in the D-III Nursing Program at Subang State Polytechnic.\n* Willing to participate in the study by signing an informed consent form.\n* Able to use Google Forms online for the intervention.\n\nExclusion Criteria:\n\n* Students who are on academic leave.\n* Students who did not complete the daily intervention until the end in groups 1 and 3.",{"count":447,"type":23},277,[26],"The goal of this clinical trial is to learn if the daily Three Good Thing intervention can prevent negative mental health outcomes like stress and burnou, and promote Gratitude and Psychological Wellbeing in undergraduate Nursing Students.\n\nThe main questions it aims to answer are:\n\nDoes the daily Three Good Things intervention effective in promoting gratitude and psychological wellbeing among nursing students?\n\nResearchers will compare four different arms from Solomon Four Group Design to see if the increase in Gratitude and Psychological Wellbeing scores is significantly greater in the groups that received the 3GT intervention.\n\nParticipants will be randomly assigned to one of the four groups, and those in the intervention groups will:\n\n1. Complete a pre-test questionnaire (for some groups) on their current level of Gratitude and Psychological Wellbeing.\n2. Perform the Three Good Things (3GT) intervention by writing down three positive things that happened each day for 7 consecutive days.\n3. Complete a post-test questionnaire to measure the final level of Gratitude and Psychological Wellbeing.",[451,452,29],"Nursing Student","Gratitude",[454,452,36,455,255,456,457],"Three Good Things","Daily intervention","Solomon Four Group Design","Positive psychology","2026-01-06",{"date":460,"type":42},"2026-01-13",{"date":462,"type":23},"2025-12-23",{"date":464,"type":23},"2026-03-25",{"name":466,"class":49},"Kaohsiung Medical University",{"id":468,"slug":469,"hasResults":12,"nctId":470,"briefTitle":471,"officialTitle":472,"acronym":4,"eligibilityCriteria":473,"healthyVolunteers":12,"sex":90,"minAge":19,"maxAge":4,"enrollmentInfo":474,"targetDuration":4,"studyType":24,"phases":475,"briefSummary":476,"conditions":477,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":481,"lastUpdatePostDateStruct":482,"startDateStruct":484,"completionDateStruct":486,"leadSponsor":488,"locationsCount":82},"100611383","phase-1-a-robot-assisted-tailored-activity-programme-for-people-with-dementia-and-their-caregivers-100611383","NCT07239869","A Robot-assisted Tailored Activity Programme for People With Dementia and Their Caregivers","An AI Robot-assisted Tailored Activity Programme for Improving the Physical Inactivity of People With Dementia and Their Informal Caregivers","Inclusion Criteria for people with dementia:\n\n* mild to moderate stage dementia at a standardized mini-mental state examination score (MMSE) higher than 10;\n* be able to walk independently;\n* being physically inactive (categorized as \"low\u002Finactive\" by the International Physical Activity Questionnaire);\n* free from other medical\u002Ffunctional conditions that would limit physical activity.\n\nExclusion Criteria for people with dementia:\n\n* high risk of falling (Berg Balance Scale \\\u003C45);\n* not be suitable for doing physical activity as recommended by the primary care physician;\n* currently involved in another interventional study involving physical exercise;\n* had acute hospitalization \\>3 times in the past year.\n\nInclusion Criteria for caregivers:\n\n* primary informal caregivers who reside with the of the person with dementia;\n* have provided care for more than six months;\n* have no intention to send the care recipient to nursing homes in the next six months;\n* being physically inactive;\n* use a smartphone.\n\nExclusion Criteria for caregivers:\n\n* caregivers with unstable physical or mental conditions;\n* cannot communicate logically;\n* not suitable for doing physical activity as recommended by a primary care physician.",{"count":167,"type":23},[134],"To assess the feasibility and preliminary efficacy of the tailored activity programme on improving the physical inactivity of the caregiving dyads.",[478,479,480,138],"Dementia","Caregiver","Physical Activity","2025-12-10",{"date":483,"type":42},"2025-12-18",{"date":485,"type":42},"2025-09-01",{"date":487,"type":23},"2026-08-31",{"name":489,"class":49},"The Hong Kong Polytechnic University",{"id":491,"slug":492,"hasResults":12,"nctId":493,"briefTitle":494,"officialTitle":495,"acronym":496,"eligibilityCriteria":497,"healthyVolunteers":12,"sex":90,"minAge":498,"maxAge":499,"enrollmentInfo":500,"targetDuration":4,"studyType":24,"phases":502,"briefSummary":503,"conditions":504,"keywords":514,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":522,"lastUpdatePostDateStruct":523,"startDateStruct":525,"completionDateStruct":527,"leadSponsor":528,"locationsCount":82},"100579744","culturally-adapted-i-cbt-for-farsidari-speaking-migrants-100579744","NCT06828276","Culturally Adapted i-CBT for Farsi\u002FDari Speaking Migrants","Culturally and Language-Adapted i-CBT for Common Mental Health Problems: A Randomized Controlled Study With Farsi\u002FDari-Speaking Migrants","i-CBT","Inclusion Criteria:\n\n* Between the ages of 15 and 29.\n* A score above the cut-off 1.75 on HSCL-25\n* Has a refugee or migrant background\n* Has a good and stable internet connection\n* Has access to a computer, tablet or smartphone\n* Is fluent in reading and writing Arabic\n* Has the ability to dedicate time to take part in the intervention for 6-10 weeks.\n\nExclusion Criteria:\n\n* Is suffering from a severe mental illness, such as psychosis or severe depression.\n* Is suffering from substance abuse\n* Is undergoing a psychological treatment\n* Has a high risk of suicide","15 Years","29 Years",{"count":501,"type":23},128,[26],"The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues among Farsi\u002FDari-speaking youth migrants and refugees. Investigator hypothesizes that there will be a significant decrease in psychological symptoms after participants receive the intervention compared to a control group.",[394,505,506,507,508,509,63,138,510,511,512,513],"Anxiety Symptoms","Grief","Psychological Trauma","Insomnia","Resilience","Marital Relationship","Wellbeing","Common Mental Health Problems","Rumination",[515,516,517,518,36,519,520,509,521],"Refugee","Cognitive behavioral therapy","Psychological problems","Persian speaking","Youth","Mental problems","Asylum seeker","2025-12-05",{"date":524,"type":42},"2025-12-12",{"date":526,"type":42},"2025-03-25",{"date":263,"type":23},{"name":529,"class":49},"Karolinska Institutet",{"id":531,"slug":532,"hasResults":12,"nctId":533,"briefTitle":534,"officialTitle":535,"acronym":536,"eligibilityCriteria":537,"healthyVolunteers":17,"sex":90,"minAge":420,"maxAge":538,"enrollmentInfo":539,"targetDuration":4,"studyType":24,"phases":541,"briefSummary":542,"conditions":543,"keywords":549,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":568,"lastUpdatePostDateStruct":569,"startDateStruct":571,"completionDateStruct":573,"leadSponsor":575,"locationsCount":577},"100609887","foundational-programs-to-combat-clinician-stress-100609887","NCT07220421","Foundational Programs to Combat Clinician Stress","Evaluate Foundational Wellness Programs to Help Reduce Clinician Burnout and Improve Professional Fulfilment in Health Care Professionals.","FACCTS","Inclusion Criteria:\n\n* 25-70 years of age,\n* UPHS or MGH clinician (physician, APP, CRNP, PA, psychologist),\n* Access to smart phone and internet,\n* Ability to give informed consent,\n* Interested in wearing an Oura ring and being part of a study to evaluate breath and meditation-derived exercises,\n* Willing to do relaxation exercise every day for 4 weeks.\n\nExclusion Criteria:\n\n* Currently maintaining a regular\u002Fdaily mind-body program practice (eg. meditation, yoga or breathing techniques),\n* Atrial fibrillation,\n* Pacemaker\u002Fdefibrillator,\n* Untreated or severe obstructive sleep apnea (AHI\\>=30),\n* History of diaphragm paralysis,\n* Unable or unwilling to complete the workshop,\n* Severe chronic obstructive pulmonary disease (COPD),\n* Severe valvular heart disease,\n* Prior or planned chest\u002Fabdominal or nasal\u002Ffacial surgery within 6 months,\n* Severe psychiatric illness (e.g. schizophrenia, schizoaffective disorder, bipolar disorder), active substance use, seizure disorder or major somatic illness (uncontrolled hypertension, lung disease, liver disease, cancer or heart disease).","70 Years",{"count":540,"type":23},180,[26],"This is a prospective, randomized, controlled clinical trial in which clinicians from University of Pennsylvania Health Systems (UPHS) including Penn Medicine- Lancaster General Health (LGH) and Massachusetts General Hospital (MGH) are offered a well-known program to help reduce clinician burnout: Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation Intervention.",[544,545,546,101,547,548],"Burnout, Professional","Stress, Psychological","Stress, Physiological","Mind-Body Therapies","Work Related Stress",[550,551,552,553,554,555,556,557,558,280,62,559,560,509,561,562,563,564,565,566,567],"Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation","Stress Reduction","Healthcare Professional Burnout","Workplace Wellbeing","Work Life Balance","Physician","Healthcare Provider","Cognitive Performance","Cognitive Attention","Sleep","Heart Rate Variability","Social Connection","Self-Valuation","Professional Fulfilment","Medical Errors","Physician Turnover","Healthcare Economics","Occupational Burnout","2025-10-21",{"date":570,"type":42},"2025-10-23",{"date":572,"type":42},"2025-09-15",{"date":574,"type":23},"2026-05",{"name":576,"class":49},"Lancaster General Hospital",6,{"id":579,"slug":580,"hasResults":12,"nctId":581,"briefTitle":582,"officialTitle":583,"acronym":4,"eligibilityCriteria":584,"healthyVolunteers":12,"sex":90,"minAge":19,"maxAge":20,"enrollmentInfo":585,"targetDuration":4,"studyType":24,"phases":587,"briefSummary":588,"conditions":589,"keywords":591,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":597,"lastUpdatePostDateStruct":598,"startDateStruct":600,"completionDateStruct":602,"leadSponsor":603,"locationsCount":82},"100564129","perfectionism-and-daily-coping-and-emotion-regulation-processes-a-trial-of-two-explanatory-feedback-interventions-100564129","NCT06625151","Perfectionism and Daily Coping and Emotion Regulation Processes: A Trial of Two Explanatory Feedback Interventions","Perfectionism and Daily Stress, Coping, and Well-Being: Testing an Explanatory Feedback Intervention","Individuals potentially interested in participating will be prescreened for levels of SC perfectionism and negative and positive mood.\n\nInclusion Criteria:\n\n* Included in the study will be students who score 0.5 standard deviation above the mean score on two or more of four brief \\[4- or 5-item\\] measures of SC perfectionism (DEQ self-criticism, FMPS concern over mistakes, HMPS socially prescribed perfectionism, and APS-R discrepancy) for previous student samples\n\nExclusion Criteria:\n\n* Individuals who meet the criteria for a diagnosis of depression or anxiety disorders and who do not have concomitant mental health care will be excluded from the study.\n* Participants will be excluded if they fail to complete any of the Time 1 measures, or seven days of the daily diary procedure.",{"count":586,"type":23},200,[26],"Over the past three decades, perfectionism has received increasing theoretical and empirical attention as a cognitive-personality factor that increases vulnerability to a wide range of psychological problems, including depression and anxiety. Although mediators and moderators of the link between perfectionism and well-being have been identified, the direct clinical utility of these findings has not been a focus. The Perfectionism and Coping Processes Model - Explanatory Feedback Intervention (PCPM-EFI) draws on previous findings and individually analyzes participant responses to perfectionism measures and online daily questionnaires of stress, coping, and mood over 7 days. The EFI provides an individualized slideshow presentation that is delivered in a single 45-60 minute session by a student research assistant to address how stress and coping patterns trigger and maintain negative affect and (lower) positive affect in the participant's daily life. A recent waitlist controlled feasibility trial compared the PCPM-EFI condition with a waitlist control condition over 4 weeks in 176 university students with higher SC perfectionism, with individualized feedback delivered one-on-one by student trainees in-person or remotely through videoconferencing. The feasibility of the individualized analyses of each participant's daily data was supported by identifying daily trigger patterns, maintenance tendencies, strengths, common triggers, and best targets for reducing negative mood and increasing positive mood across several stressors for each participant. Participant ratings indicated that the comprehensive feedback was coherent and functional. Participants in the EFI condition, compared to those in the control condition, reported increases in empowerment, coping self-efficacy, and problem-focused coping, as well as decreases in depressive and anxious symptoms. Between-group effect sizes were moderate-to-large. There were reliable improvements in empowerment and depressive symptoms for 56% and 36%, respectively, of participants in the EFI condition. These findings demonstrate the broad applicability, conceptual utility, and effectiveness of the PCPM-EFI for self-critical perfectionistic individuals. Given these promising findings, research is needed to examine the utility of customizing daily emotion regulation findings, and the complementary effects of providing meaningful feedback on well-being.\n\nThe present study will build on the promising findings of the PCPM-EFI by using a 7-day daily diary methodology to test a complementary EFI on perfectionism and emotion regulation processes (e.g., self-compassion, mindfulness, experiential avoidance, rumination, reappraisal) delivered online through videoconferencing in a sample of university students with higher self-critical perfectionism. Based on the Perfectionism and Emotion Regulation Processes Model (PERPM), the PERPM-EFI follows the same structure as the PCPM-EFI to provide individualized analyses drawn from previous findings. The results of a pilot study of 12 university students with higher SC perfectionism suggest that the PERPM-EFI is broadly applicable, conceptually useful, and effective. Specifically, despite the small sample size, participants reported increases in empowerment, mindfulness, self-compassion, and emotional self-awareness, as well as decreases in depressive and anxious symptoms. The present study will use a randomized control design to examine whether the PCPM-EFI plus PERPM-EFI can better improve well-being, relative to providing no feedback, the PERPM-EFI alone, or PCPM-EFI alone in the context of a 4-week longitudinal study with three time points in a sample of 180 university students. The four conditions will be: (a) waitlist control condition, (b) PCPM-EFI, (c) PERPM-EFI, and (d) PCPM-EFI plus PERPM-EFI. It is hypothesized that all three EFI conditions will yield better outcomes than the waitlist control condition. It is also hypothesized that the combined PCPM-EFI plus PERPM-EFI condition will be superior to the PCPM-EFI condition and PERPM-EFI condition on empowerment (primary outcome) and secondary symptom outcomes (i.e., depressive symptoms, anxious symptoms, negative affect, positive affect). It is also expected that participants in the PCPM-EFI plus PERPM-EFI condition and PCPM-EFI condition will exhibit larger increases in coping self-efficacy and problem-focused coping than participants in the PERPM-EFI condition. On the other hand, it is hypothesized that participants in the PCPM-EFI plus PERPM-EFI condition and PERPM-EFI condition will exhibit larger increases in self-compassion, mindfulness, and emotional self-awareness than participants in the PCPM-EFI condition. If the feedback interventions are shown to be efficacious, the interventions could be offered to universities, work places, clinical settings, and other organizations.",[590,29,426],"Perfectionism",[590,63,592,593,594,595,596],"Coping","Emotion Regulation","Mood","Daily Diary","Feedback Intervention","2025-09-22",{"date":599,"type":42},"2025-09-23",{"date":601,"type":42},"2024-10-23",{"date":236,"type":23},{"name":604,"class":49},"McGill University",{"id":606,"slug":607,"hasResults":12,"nctId":608,"briefTitle":609,"officialTitle":610,"acronym":4,"eligibilityCriteria":611,"healthyVolunteers":12,"sex":18,"minAge":612,"maxAge":613,"enrollmentInfo":614,"targetDuration":4,"studyType":24,"phases":616,"briefSummary":617,"conditions":618,"keywords":624,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":633,"lastUpdatePostDateStruct":634,"startDateStruct":636,"completionDateStruct":638,"leadSponsor":640,"locationsCount":642},"100589168","contemplative-practice-for-well-being-and-self-deconstruction-in-women-100589168","NCT06950905","Contemplative Practice for Well-being and Self-Deconstruction in Women","Effectiveness of a Contemplative Practice on Psychological Well-Being, Self-Deconstruction, Body Image, Body Acceptance, and Compassion in Women","Inclusion Criteria:\n\n* Sex assigned female at birth and self-identifies as a woman\n* Aged between 30 and 60 years\n* Spanish nationality, or residency in Spain for more than 5 years\n* Fluent in Spanish\n* At least one month of experience with meditation or mindfulness practices, with a regular practice of more than 15 minutes per session\n* Provides informed consent\n\nExclusion Criteria:\n\n* Indicators of eating disorders (ED) or mental health deterioration, determined by the following cut-off points: SCOFF ≥ 2 and PHQ-9 ≥ 10\n* Formal diagnosis of an eating disorder or any psychiatric condition\n* Substance use disorder\n* History of neurological disease diagnosis\n* Participant's decision to withdraw from the study at any point","30 Years","60 Years",{"count":615,"type":23},122,[26],"This randomized controlled trial aims to evaluate the effectiveness of a contemplative practice called Feeding Your Demons (FYD), based on a secular adaptation of Tibetan Buddhism, in improving psychological well-being, body image, body acceptance, compassion, and self-deconstruction in adult women. Participants will be randomly assigned to either FYD or an active control group practicing mindfulness meditation. Psychological variables will be assessed before and after the intervention, and at a six-month follow-up. Additionally, a qualitative exploration will be conducted through interviews with a subgroup of participants.",[619,620,621,113,622,623,102,29],"Mental Health","Self Concept","Body Dissatisfaction","Self-Perception","Mindfulness Meditation",[625,626,627,628,102,113,629,630,631,632,71],"Feeding Your Demons","Self-Deconstruction","Selflessness","Contemplative Practices","Body Image","Women's Mental Health","Randomized Controlled Trial (RCT)","mindfulness","2025-09-09",{"date":635,"type":42},"2025-09-10",{"date":637,"type":42},"2025-06-18",{"date":639,"type":23},"2028-06-30",{"name":641,"class":49},"Hospital Miguel Servet",2,{"id":644,"slug":645,"hasResults":12,"nctId":646,"briefTitle":647,"officialTitle":647,"acronym":4,"eligibilityCriteria":648,"healthyVolunteers":12,"sex":90,"minAge":19,"maxAge":4,"enrollmentInfo":649,"targetDuration":4,"studyType":24,"phases":651,"briefSummary":652,"conditions":653,"keywords":656,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":660,"lastUpdatePostDateStruct":661,"startDateStruct":663,"completionDateStruct":665,"leadSponsor":667,"locationsCount":82},"100604299","interventions-to-promote-well-being-and-social-relationships-among-university-students-100604299","NCT07147712","Interventions to Promote Well-being and Social Relationships Among University Students","Inclusion Criteria:\n\n* University students regularly enrolled at the University of Padua\n* Aged 18 years or older\n* Able to understand and complete the questionnaires in Italian or English\n* Residing in Padova or its province during the study period\n* Providing informed consent for participation\n\nExclusion Criteria:\n\n* Presence of severe psychological conditions requiring immediate or specialized clinical care, as identified during the initial screening interview\n* Inability or unavailability to attend group sessions for the full 6-week duration",{"count":650,"type":23},50,[26],"This study evaluates the impact of a psychological group intervention aimed at promoting well-being and social connectedness among university students. The intervention is part of the UNIST-HEALTH (PRO-BEN) initiative and targets students enrolled at the University of Padua. Participants will be randomly assigned to either an intervention group or a waitlist control group. The intervention consists of six weekly group sessions focused on psychoeducation and experiential activities designed to enhance the quality of social relationships, reduce loneliness, and improve psychological well-being. Assessments will be conducted at baseline, post-intervention, and at a four-week follow-up.",[654,138,655],"Loneliness","Social Relationship",[283,657,658,659],"well being","social relationships","socialization","2025-08-21",{"date":662,"type":42},"2025-08-29",{"date":664,"type":42},"2025-05-01",{"date":666,"type":23},"2025-12-31",{"name":294,"class":49},{"id":669,"slug":670,"hasResults":12,"nctId":671,"briefTitle":672,"officialTitle":673,"acronym":674,"eligibilityCriteria":675,"healthyVolunteers":17,"sex":90,"minAge":19,"maxAge":4,"enrollmentInfo":676,"targetDuration":4,"studyType":24,"phases":678,"briefSummary":679,"conditions":680,"keywords":682,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":684,"lastUpdatePostDateStruct":685,"startDateStruct":687,"completionDateStruct":689,"leadSponsor":690,"locationsCount":4},"100602074","the-young-ambassadors-supporting-caregivers-program-100602074","NCT07118774","The Young Ambassadors Supporting Caregivers Program","The Effect of the Young Ambassadors Supporting Caregivers (YASC) Program: A Dual Randomized Controlled Trial","YASC","Volunteer Recruitment and Eligibility\n\nThis study will recruit university students in Hong Kong as youth volunteers. Eligible participants must meet the following criteria:\n\n1. Aged 18-35 years;\n2. Willing to complete training and commit to at least 2 hours of volunteer service per week for 6 weeks;\n3. No self-reported major physical or mental health conditions, including cognitive impairment;\n4. Limited prior formal volunteering experience (≤4 engagements in the past year).\n\nOlder Adult Caregiver Recruitment and Eligibility\n\nWe will recruit community-dwelling Chinese adults in Hong Kong who provide care for older adults. Eligible caregivers must:\n\n1. Be aged 50 years or older;\n2. Consent to interact with youth volunteers at least four times during the intervention;\n3. Report no major physical or mental health conditions, including cognitive impairment; and\n4. Have resided with and provided care for an older adult (aged 65+) for a minimum of one year.",{"count":677,"type":23},120,[26],"This RCT will provide preliminary evidence on effective training for young adult volunteers to support older adult caregivers, addressing Hong Kong's aging crisis and caregiver burden. The objectives of this study include:\n\n1. To examine the feasibility and acceptability of the interventions in Hong Kong's cultural context.\n2. To evaluate the effects of three trainings (mindfulness\u002Fcompassion, caregiving skills, communication skills) on young adult volunteers' preparedness for caregiving, meaning of life, and civic engagement.\n3. To assess the impact of volunteer services on caregivers' depression, anxiety, and caregiver burden.",[29,681],"Caregiver Burden of Caregivers",[683],"volunteer","2025-08-05",{"date":686,"type":42},"2025-08-12",{"date":688,"type":23},"2025-10-01",{"date":207,"type":23},{"name":691,"class":49},"The University of Hong Kong",{"id":693,"slug":694,"hasResults":12,"nctId":695,"briefTitle":696,"officialTitle":697,"acronym":4,"eligibilityCriteria":698,"healthyVolunteers":12,"sex":90,"minAge":19,"maxAge":20,"enrollmentInfo":699,"targetDuration":4,"studyType":334,"phases":4,"briefSummary":701,"conditions":702,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":706,"lastUpdatePostDateStruct":707,"startDateStruct":708,"completionDateStruct":710,"leadSponsor":711,"locationsCount":82},"100586945","brain-function-and-psychological-changes-related-to-cell-therapy-for-autoimmune-hemolytic-anemia-100586945","NCT06921980","Brain Function and Psychological Changes Related to Cell Therapy for Autoimmune Hemolytic Anemia","Brain Function and Psychological Assessment in Patients With Autoimmune Hemolytic Anemia Undergoing Cell Therapy","Inclusion Criteria:\n\n* Diagnosis of AIHA\n* Subjects will receive cell therapy such as CAR T-cell therapy\n* Male or female, aged 18-65 years\n* Willing and able to comply with the requirements for this study and written informed consent\n\nExclusion Criteria:\n\n* History of psychiatric illness\n* History of severe brain disease\n* Subjects that the investigator believes have other reasons that make them unsuitable for inclusion in this study",{"count":700,"type":23},20,"Cell therapy is an innovative treatment with significant efficacy in hematologic and certain autoimmune diseases. Although it offers potential benefits for autoimmune hemolytic anemia (AIHA), it may result in cognitive and other potential impairments, which can adversely affect patients' cognition and behavior.\n\nBrain function and psychological assessment are essential for the early detection of potential impairments, allowing timely interventions to prevent complications and ensure patient safety. This study aims to comprehensively evaluate the physical and psychological impacts of cell therapy on AIHA patients to develop safer and more effective treatment strategies that enhance their quality of life.",[703,704,705,101],"CAR T-cell Therapy","Autoimmune Hemolytic Anemia","Brain Function","2025-07-31",{"date":684,"type":42},{"date":709,"type":42},"2025-02-25",{"date":263,"type":23},{"name":712,"class":49},"Institute of Hematology & Blood Diseases Hospital, China",{"id":714,"slug":715,"hasResults":12,"nctId":716,"briefTitle":717,"officialTitle":718,"acronym":4,"eligibilityCriteria":719,"healthyVolunteers":17,"sex":90,"minAge":188,"maxAge":361,"enrollmentInfo":720,"targetDuration":4,"studyType":24,"phases":722,"briefSummary":723,"conditions":724,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":726,"lastUpdatePostDateStruct":727,"startDateStruct":729,"completionDateStruct":731,"leadSponsor":733,"locationsCount":82},"100590779","just-act-for-student-well-being-100590779","NCT06971861","Just ACT for Student Well-being","Just ACT: School-Based Program Using Acceptance and Commitment Therapy (ACT) to Promote Student Well-being","Inclusion Criteria:\n\n* age of 35 years or below\n* fluency in oral and written Chinese\n\nExclusion Criteria:\n\n* active or current history of psychosis, bipolar disorder, or personality disorder\n* active or current report of suicidal attempts\n* active or current suicidal ideations for more than half the days\n* any history of intellectual deficits",{"count":721,"type":23},96,[26],"Most psychological conditions start developing during adolescent years. This makes adolescence an ideal and critical window for prevention efforts that help enhance stress management and mental health among the younger generations. This pilot study aims to develop a brief prevention program that focuses on youths' well-being and living as guided by their personal values.",[725,29],"Acceptance and Commitment Therapy","2025-07-29",{"date":728,"type":42},"2025-08-01",{"date":730,"type":42},"2025-06-04",{"date":732,"type":23},"2028-10-21",{"name":691,"class":49},{"id":735,"slug":736,"hasResults":12,"nctId":737,"briefTitle":738,"officialTitle":738,"acronym":4,"eligibilityCriteria":739,"healthyVolunteers":12,"sex":90,"minAge":740,"maxAge":741,"enrollmentInfo":742,"targetDuration":4,"studyType":24,"phases":744,"briefSummary":745,"conditions":746,"keywords":748,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":751,"lastUpdatePostDateStruct":752,"startDateStruct":754,"completionDateStruct":756,"leadSponsor":758,"locationsCount":82},"100596805","bridging-the-divide-a-pioneering-culturally-specific-mentoring-intervention-to-increase-support-for-at-risk-youth-100596805","NCT07050251","Bridging the Divide: A Pioneering Culturally-Specific Mentoring Intervention to Increase Support for At-Risk Youth","Inclusion Criteria:\n\n* actively enrolled in the partnering community organization (e.g., Boys and Girls Clubs)\n* Participants and their caregivers must be able to provide informed assent\u002Fconsent in English. Parental Consent: Participants must have parental or guardian consent to participate in the study.\n* Self-identifies as a racial-ethnic minority (i.e., Black\u002FAfrican American, Hispanic, etc.)\n\nExclusion Criteria:\n\n* Current participation in another mentoring program: To avoid confounding the results, youth currently involved in other mentoring or structured socio-emotional support programs will be excluded.\n* Severe cognitive or developmental disabilities: The study will exclude participants with mental impairments that prevent meaningful engagement in focus groups or intervention activities.","12 Years","16 Years",{"count":743,"type":23},30,[26],"The purpose of this study is to assess the feasibility, acceptability, and effectiveness of a culturally-specific mentoring intervention to improve socio-emotional skills, psychological well-being, and social support among at-risk youth and to evaluate the proposed mentoring intervention's impact on academic outcomes, social behavior, and caregiver perceptions of social-emotional competencies. Additionally, it seeks to gather stakeholder feedback to refine the intervention further.",[747,101],"Socio-emotional Well-being",[749,750],"at risk youth","Boys and Girls Clubs","2025-06-25",{"date":753,"type":42},"2025-07-03",{"date":755,"type":23},"2025-06-27",{"date":757,"type":23},"2025-08-15",{"name":759,"class":49},"The University of Texas Health Science Center, Houston"]