[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pudendal-neuralgia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pudendal-neuralgia":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,47,70,92,117,144,164],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100620321","conventional-versus-high-voltage-long-duration-pulsed-radiofrequency-of-the-pudendal-nerve-100620321",false,"NCT07356102","Conventional Versus High-Voltage Long-Duration Pulsed Radiofrequency of the Pudendal Nerve","Comparing Conventional and High-Voltage Long-Duration Pulsed Radiofrequency Applied to the Pudendal Nerve in the Treatment of Pudendal Neuralgia: A Randomized Controlled Trial","Inclusion Criteria\n\n* Adults aged 18 years or older\n* Diagnosis of pudendal neuralgia according to the Nantes diagnostic criteria\n* Followed at the Algology (Pain Medicine) outpatient clinic\n* Chronic pudendal neuralgia refractory to conservative treatment or intolerance to conservative therapies\n* Not using neuropathic pain medications, or on a stable dose for at least 3 months prior to enrollment\n* Ability to comply with study procedures and follow-up visits\n* Ability to understand the study information and provide written informed consent\n\nExclusion Criteria\n\n* Presence of pelvic organic pathologies that may cause pudendal pain\n* Pain limited only to the coccygeal, gluteal, or lower abdominal regions\n* Patients with purely paroxysmal pain, isolated pruritus, or imaging findings that fully explain symptoms\n* History of malignancy or autoimmune disease\n* Previous surgery that may have altered the anatomy of the pudendal nerve region\n* Pregnancy or suspected pregnancy\n* Presence of a cardiac pacemaker or implanted electrical device\n* Use of anticoagulant therapy or presence of uncorrectable coagulation disorders\n* Active systemic infection or infection at the injection site\n* Known hypersensitivity to metals\n* Inability or unwillingness to provide informed consent","ALL","18 Years",{"count":19,"type":20},38,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study is a single-center, prospective, randomized controlled trial evaluating two types of pulsed radiofrequency (PRF) treatment for patients with pudendal neuralgia. Pudendal neuralgia is a chronic neuropathic pain affecting the perineum and pelvic area, often causing significant discomfort and reduced quality of life.\n\nPatients will be randomly assigned to receive either conventional PRF or high-voltage long-duration PRF applied to the pudendal nerve. The study aims to compare the clinical effectiveness, pain relief, and safety of the two treatment approaches. Participants will be monitored for pain improvement, functional outcomes, and any treatment-related side effects.\n\nThe study follows standard clinical procedures and all treatments are performed under sterile conditions with proper monitoring to ensure patient safety.",[26],"Pudendal Neuralgia",[26,28,29,30,31,32,33],"Pudendal Nerve","Pulsed Radiofrequency","PRF","Conventional PRF","High-Voltage Long-Duration PRF","Chronic Pelvic Pain","RECRUITING","2026-01-21",{"date":37,"type":38},"2026-01-22","ACTUAL",{"date":40,"type":38},"2025-02-19",{"date":42,"type":20},"2026-12",{"name":44,"class":45},"Ankara City Hospital Bilkent","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":46},"100583139","phase-3-evaluation-of-the-efficacy-of-therapeutic-infiltrations-of-the-pudendal-nerve-performed-under-neurostimulation-on-pain-1-month-after-an-infiltration-of-local-anaesthetic-in-the-treatment-of-pudendal-neuralgia-100583139","NCT06872437","Evaluation of the Efficacy of Therapeutic Infiltrations of the Pudendal Nerve, Performed Under Neurostimulation on Pain, 1 Month After an Infiltration of Local Anaesthetic, in the Treatment of Pudendal Neuralgia.","EFFICACY OF THE USUAL TREATMENT WITH INFILTRATION OF LOCAL ANAESTHETIC IN THE TREATMENT OF PUDENDAL NEURALGIA: A RANDOMISED TRIAL COMPARED WITH A PHYSIOLOGICAL SERUM","EPHI-DACI","Inclusion Criteria:\n\n* Patient 18 years of age or older,\n* Expressed consent to participate in the study\n* Affiliated or beneficiary of a social security plan\n* With pudendal neuralgia (Nantes criteria \"modified\" Nantes criteria).\n* MRI normal or without pathology explaining the pain\n* Drug treatment failure as defined in the LOS, i.e., failure (VAS decrease \\\u003C 3) of at least one antiepileptic drug and an antidepressant whose dosages have been to the maximum possible dosage, or in whom a side effect for whom a side effect could not allow the dose to be increased to its to its maximum allowed dose.\n\nExclusion Criteria:\n\n* Patient benefiting from a legal protection measure\n* Pregnant or breastfeeding woman\n* General and\u002For local infection (fistulous or cutaneous suppuration of the anal margin) in progress\n* Known neurological pathology that may explain the pain\n* Psychiatric pathology requiring a drug treatment treatment\n* Anticoagulants or haemostasis disorders\n* Hypersensitivity to lidocaine hydrochloride, to local anesthetics\n* Recurrent porphyrias",{"count":56,"type":20},60,[58],"PHASE3","Pudendal neuralgia (PN) is a chronic nerve compression syndrome causing neuropathic pain. Treatment includes medication, infiltration and decompressive surgery. Medicinal treatment involves the use of drugs that have proved effective in other areas, such as shingles or diabetes. There is no consensus on the molecules to be used for pudendal nerve infiltration (PNTI), and less than half of patients experience short-term relief. The only risk factor for failure is the duration of pain. Our study proposes to compare the usual treatment with a placebo, as no type of infiltration has been compared with a placebo.",[26],"2025-05-16",{"date":63,"type":38},"2025-05-18",{"date":65,"type":38},"2023-12-08",{"date":67,"type":20},"2029-03-08",{"name":69,"class":45},"Groupe Hospitalier Diaconesses Croix Saint-Simon",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":79,"phases":4,"briefSummary":80,"conditions":81,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":46},"100577307","perioperative-medical-program-to-optimize-nerve-regeneration-after-robot-assisted-laparoscopic-neurolyses-of-pudendal-andor-inferior-cluneal-nerves-for-chronic-neuralgias-results-after-1-year-follow-up-100577307","NCT06796595","Perioperative Medical Program to Optimize Nerve Regeneration After Robot-assisted Laparoscopic Neurolyses of Pudendal and\u002For Inferior Cluneal Nerves for Chronic Neuralgias: Results After 1-year Follow-up","REGEN","Inclusion Criteria:\n\n* Patients over 18 years old\n* Patients presenting a pudendal and\u002For inferior cluneal neuralgias with failure of the medical treatment\n* Patient having given consent after reading the information note\n\nExclusion Criteria:\n\n* Inoperable patients (contraindications to anesthesia or surgery) surgical contraindications)\n* Person deprived of liberty or under guardianship\n* Person under court protection\n* Pregnant or breast-feeding woman\n* Minors",{"count":78,"type":20},20,"OBSERVATIONAL","Pudendal and inferior cluneal neuralgias are responsible for chronic pelvicperineal pain. These two neuralgias are associated in approximately 25% of cases. In the event of failure of first-line multimodal medical treatment, a mini-invasive robot-assisted laparoscopic decompression can be proposed. These surgeries carry the risk of neurapraxia, leading to a temporary increase in neuropathic pain and numbness in the nerve sensitive area, a motoric or neurovegetative disturbance (pudendal).",[26,82],"Neuralgia","2025-01-27",{"date":85,"type":38},"2025-01-28",{"date":87,"type":20},"2025-01-23",{"date":89,"type":20},"2027-01-31",{"name":91,"class":45},"UBOSGA",{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":99,"sex":100,"minAge":17,"maxAge":4,"enrollmentInfo":101,"targetDuration":4,"studyType":21,"phases":103,"briefSummary":105,"conditions":106,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":46},"100565598","phase-4-transvaginal-versus-fluoroscopy-guided-trans-gluteal-pudendal-nerve-block-for-pudendal-neuralgia-100565598","NCT06644261","Transvaginal Versus Fluoroscopy-guided Trans Gluteal Pudendal Nerve Block for Pudendal Neuralgia","Transvaginal Versus Fluoroscopy-guided Trans Gluteal Pudendal Nerve Block for Pudendal Neuralgia and Chronic Pelvic Pain: a Prospective, Noninferiority, Randomized Controlled Trial","Inclusion Criteria:\n\n* women \\>18 years\n* English speaking\u002Freading\n* Diagnosis of pudendal neuralgia OR chronic pelvic pain with pain in the distribution of the pudendal nerve for 3 months or longer\n* Minimum pain\u002Fbother score of 4\u002F10\n* Desire for pudendal nerve block\n\nExclusion Criteria:\n\n* Contraindication to pudendal nerve block (examples: skin or vaginal infection, bupivacaine allergy, uncorrected coagulopathy)\n* Pregnant or intending to become pregnant during the study\n* Pudendal nerve block from any route within the last 3 months\n* Major pelvic surgery within the last 3 months (examples: hysterectomy, prolapse repair, midurethral sling)\n* Neurologic disease affecting the perineum (examples: spinal cord injury, multiple sclerosis)",true,"FEMALE",{"count":102,"type":20},40,[104],"PHASE4","Chronic pain affecting the pelvic and urogenital area is a major clinical problem and can have a profound impact on quality of life and health care costs. Pelvic pain arising from entrapment or neuropathy of the pudendal nerve is known as pudendal neuralgia, which results in chronic perineal pain. This pain syndrome is difficult to diagnose and patients with pudendal neuralgia may present to providers with refractory chronic pelvic pain. Pudendal nerve infiltration or pudendal nerve block (PNB) serves as a diagnostic tool and treatment modality for patients with this condition. To date, there are no published randomized controlled trials comparing imaging-guided PNB to transvaginal finger-guided PNB. While one can assume that image-guided nerve blocks will provide better accuracy for injection and potentially better efficacy in pain relief as a result, no published data exists comparing the outcomes and efficacy between modalities.\n\nThe purpose of this prospective, non-inferiority, randomized controlled trial is to compare the efficacy of pain relief from bilateral transvaginal finger-guided pudendal nerve block versus bilateral fluoroscopy-guided trans gluteal pudendal nerve block for patients with pudendal neuralgia.",[26,107],"Chronic Pelvic Pain Syndrome","2024-12-13",{"date":110,"type":38},"2024-12-18",{"date":112,"type":38},"2024-06-27",{"date":114,"type":20},"2029-07-01",{"name":116,"class":45},"University of Louisville",{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":123,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":125,"targetDuration":4,"studyType":79,"phases":4,"briefSummary":126,"conditions":127,"keywords":128,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":46},"100560562","decompression-of-pudendal-and-inferior-cluneal-nerves-using-robot-assisted-laparoscopy-for-entrapment-neuralgias--the-x-deco-study-100560562","NCT06578767","Decompression of Pudendal and Inferior Cluneal Nerves Using Robot-assisted Laparoscopy for Entrapment Neuralgias : the X-DECO Study","Decompression of Pudendal and Inferior Cluneal Nerves Using Robot-assisted Laparoscopy for Entrapment Neuralgias: Results After 1 Year of Follow-up (the X-DECO Study)","X-DECO","Inclusion Criteria:\n\n* Patients over 18 years old\n* Patients presenting a pudendal and inferior cluneal entrapment neuralgia with 5 positive\"Nantes criteria\", and failure of the medical treatment\n* Patient having given consent after reading the information note\n\nExclusion Criteria:\n\n* Absence of any \"Nantes criteria\",\n* Patient non suitable for surgery\u002Fgeneral anesthesia",{"count":78,"type":20},"The objective of our study is to evaluate the efficacy of the laparoscopic robot-assited approach after 1 year of follow-up, on pain experience, and anxiety, depression, post-traumatic stress syndrome and quality of life.",[26],[129,130,131,132,133,134,135],"pudendal","inferior cluneal","robot","surgery","decompression","neurolysis","laparoscopy","2024-10-07",{"date":138,"type":38},"2024-10-10",{"date":140,"type":38},"2024-07-31",{"date":142,"type":20},"2025-07",{"name":91,"class":45},{"id":145,"slug":146,"hasResults":11,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":30,"eligibilityCriteria":150,"healthyVolunteers":11,"sex":100,"minAge":17,"maxAge":4,"enrollmentInfo":151,"targetDuration":4,"studyType":21,"phases":152,"briefSummary":153,"conditions":154,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":46},"100551532","combined-prf-of-the-pudendal-nerve-with-ganglion-impar-block-effectively-alleviates-pudendal-neuralgia-100551532","NCT06461312","Combined PRF of the Pudendal Nerve With Ganglion Impar Block Effectively Alleviates Pudendal Neuralgia","Combined Pulsed Radiofrequency of the Pudendal Nerve With Ganglion Impar Block Effectively Alleviates Pudendal Neuralgia","Inclusion Criteria:\n\n1. Age between 18 and 80 years old;\n2. Diagnosis of pudendal neuralgia meets the Nantes criteria. essential criteria include the following：1）Pain in the territory of the pudendal nerve；2） Pain is predominantly experienced while sitting；3) The pain does not wake the patient at night；4）Pain with no objective sensory impairment；5）Pain relieved by diagnostic pudendal nerve block；\n3. Received conservative treatment for more than 3 months, and either had poor response to conservative treatment or intolerable medication side effects.\n4. Capable of signing informed consent form.\n\nExclusion Criteria:\n\n1. Pain caused by pelvic malignant diseases or autoimmune diseases;\n2. Pain caused by pelvic surgery;\n3. Taking anticoagulant drugs or having abnormal coagulation function;\n4. Pregnancy;\n5. Systemic infectious diseases;\n6. Inability to complete scale assessments.",{"count":102,"type":20},[23],"Patients with pudendal neuralgia suffer from long-term pain, which severely affects their quality of life. Due to unclear etiology, there is a lack of specific treatment methods. The aim of this study is to evaluate the efficacy of combined pulsed radiofrequency with ganglion impar block therapy helps evaluate the effectiveness of this treatment method for pudendal neuralgia, comparing it with traditional treatments or single interventions, and providing guidance for clinical practice.",[26,29],"2024-06-11",{"date":157,"type":38},"2024-06-17",{"date":159,"type":38},"2023-05-01",{"date":161,"type":20},"2024-12-31",{"name":163,"class":45},"Peking University People's Hospital",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":171,"targetDuration":4,"studyType":79,"phases":4,"briefSummary":172,"conditions":173,"keywords":174,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":46},"100547846","targeting-the-conus-medullaris-with-ecap-controlled-closed-loop-scs-for-treatment-of-chronic-pelvic-pain-hope-trial-100547846","NCT06413277","Targeting the Conus Medullaris With ECAP-Controlled Closed-Loop SCS for Treatment of Chronic Pelvic Pain: HOPE Trial","Targeting the Conus Medullaris With ECAP-Controlled Closed-Loop SCS for the Treatment of Chronic Pelvic Pain: HOPE Trial","Inclusion Criteria:\n\n1. Subject is 18 years of age or older at the time of enrollment.\n2. Subject has a minimum Visual Analog Scale (VAS) score of 60 mm or higher (where 100 mm pain) at baseline.\n3. Subject has been diagnosed with chronic intractable pain of the trunk and\u002For limbs specifically related to pelvic\u002Fgenital\u002Fperineal\u002Fanorectal pain, which has been refractory to conservative therapy for a minimum of 6 months.\n4. Subject has pain resulting from a known injury (surgery or trauma).\n5. Subject has been clinically diagnosed with chronic pelvic pain (pain that occurs in the region of the pelvis), including diagnoses such as, but not limited to, complex regional pain syndrome (CRPS types 1 and 2), postsurgical pain, post-traumatic injury pain, interstitial cystitis\u002Fpainful bladder syndrome, post-hysterectomy pain, post-prostatectomy pain, vulvodynia, chronic ovarian pain, and pudendal neuralgia of a known cause.\n6. Subject is an appropriate candidate for the surgical procedures required in this study based on the clinical judgment of the implanting physician.\n7. Subject is willing and capable of giving informed consent.\n8. Subject is willing and able to comply with study-related requirements, procedures, and visits.\n\nExclusion Criteria:\n\n1. Subject is pregnant or nursing.\n2. Subject is involved in a malignancy or injury claim under current litigation or has pending\u002Fapproved worker's compensation claim.\n3. Subject's mechanism of pain is unknown.\n4. Suspected cause and onset of pain are more than 30 days apart.\n5. Subject has history of small fiber neuropathy, mitochondrial disease, fibromyalgia, addiction, CRPS in secondary pain area, and\u002For atypical facial pain.\n6. Subject has been diagnosed with Crohn's Disease, Irritable Bowel Syndrome, ulcerous colitis, or any other inflammatory disease that is ongoing.\n7. Subject has a medical condition or pain in other area(s), not intended to be treated with SCS, that could interfere with study procedures, as determined by the Investigator.\n8. Subject has a history of sexual abuse and\u002For sexual trauma.\n9. Subject has a history of unmanaged depression or anxiety that pre-dates the onset of symptoms.\n10. Subject is using greater than 100 MME (morphine milligram equivalents) of opioids at baseline.\n11. Subject shows evidence of an active, disruptive psychological or psychiatric disorder or other known condition significant enough to impact perception of pain, compliance of intervention, and\u002For ability to evaluate treatment outcomes.\n12. Subject has previous neuromodulation experience including SCS (Spinal Cord Stimulator) and\u002For DRG (Dorsal Root Ganglion).\n13. Subject has an existing drug pump and\u002For SCS system, or another active implantable device such as a pacemaker, deep brain stimulator, or sacral nerve stimulator.\n14. Subject is concomitantly participating in another clinical study.",{"count":78,"type":20},"The aim of the study is to evaluate the effectiveness of using ECAP (electrically evoked compound action potential)-controlled CL (closed-loop) SCS (spinal cord stimulation) to treat chronic pelvic pain by stimulating an area in the spine called the conus medullaris (the lowermost tapering extremity of the spinal cord).",[33,26],[33,26,175],"Levator Ani Syndrome","2024-05-10",{"date":178,"type":38},"2024-05-14",{"date":180,"type":38},"2024-02-05",{"date":182,"type":20},"2027-01-01",{"name":184,"class":45},"Ainsworth Institute of Pain Management"]