[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pulmonary-edema-with-heart-failure\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pulmonary-edema-with-heart-failure":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,38],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":5},"100362434","mri-assessment-of-pulmonary-edema-in-acute-heart-failure-100362434",false,"NCT03999138","MRI Assessment of Pulmonary Edema in Acute Heart Failure","MAP-AHF","Inclusion Criteria:\n\n* 18 years of age or older and willing\u002Fable to provide informed consent\n* patients being treated for acute heart failure (including those patients with both reduced and preserved ejection fraction)\n* patients receiving medical therapy for pulmonary edema by current standard of care (including oral or IV diuretics)\n* patients identified within 48 hours of initiation of medical therapy for pulmonary edema, defined as the time of first diuretic (IV or PO) or escalation of existing diuretic therapy administered within the ED or hospital\n\nExclusion Criteria:\n\n* contraindication to MRI\n* patient too critically ill\u002Funstable as per the clinical care team for transport to MRI scanner within the required scanning window\n* moderate to severe dementia","ALL","18 Years",{"count":19,"type":20},300,"ESTIMATED","OBSERVATIONAL","Researchers are testing a more accurate way to measure how much fluid is in the lungs (also called pulmonary edema, or \"increased lung water\") in people with Heart Failure (HF) using MRI (Magnetic Resonance Imaging). There is little known about the exact level of lung water in patients with AHF or how these levels change from the time of hospital admission to discharge. The purpose of this research study is to measure the lung water in patients hospitalized for HF, to determine the change in lung water over the course of hospitalization and treatment, and to find out if lung water levels can predict if patients are higher or lower risk for returning to the hospital or dying from heart failure.",[24,25],"Acute Heart Failure","Pulmonary Edema With Heart Failure","RECRUITING","2026-05-04",{"date":29,"type":30},"2026-05-08","ACTUAL",{"date":32,"type":30},"2019-01-02",{"date":34,"type":20},"2027-12-31",{"name":36,"class":37},"University of Alberta","OTHER",{"id":39,"slug":40,"hasResults":11,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":46,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":48,"conditions":49,"keywords":54,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":68},"100437231","simultaneous-cardiac-surgery-and-micronet-covered-stent-carotid-revascularization-in-high-perioperative-stroke-risk-patients-100437231","NCT04973579","Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients","SIMultaneous Urgent Cardiac Surgery and Endovascular Stroke Prevention Using the Micronet-covered CGUARD Stent in Hemodynamically Compromised Patients at Increased Peri-operative Stroke Risk: SIM-GUARD Study","SIM-GUARD","Inclusion Criteria:\n\n* Patients eligible for concomitant carotid artery stenting in conjunction with cardiac surgery based on Heart Team and NeuroVascular Team reccomendation and according to local standards of practice.\n* Signed informed consent form\n* Consent to (routinely performed in this group of patients) follow-up visits and tests performed (routinely) during long-term follow-up\n* De novo atherosclerotic lesions or neo-atherosclerosis.\n* Symptomatic patients (with a history of ipsilateral transient cerebral ischemia, stroke or amaurosis fugax within the past 6 months) with carotid artery stenosis ≥50% as assessed by NASCET angiography or\n* Asymptomatic patients with carotid artery stenosis ≥70-80% as assessed by angiography (NASCET method).\n* Coronary angiography-confirmed multivessel disease or left main stem stenosis with the symptoms of unstable angina or non-ST-segment elevation myocardial infarction.\n* Severe symptomatic valvular disease detected by echocardiography.\n\nExclusion Criteria:\n\n* Expected survival time \\\u003C1 year (e.g., cancer).\n* Renal failure with GFR \\\u003C 20 ml\u002Fmin\u002F1.73 m2 as calculated by the CKD-EPI formula\n* Women who are pregnant (pregnancy test).\n* Coagulopathies.\n* History of hypersensitivity to a contrast agent that does not respond to pharmacotherapy.\n* Total carotid artery occlusion.\n* Stent in the carotid artery that protrudes into the aortic arch.\n* Anatomic variants that preclude stent implantation.\n* Significant stenosis of the common carotid artery proximal to the target lesion.\n* Mobile atherosclerotic plaques in the aortic arch.\n* Anatomy of the coronary arteries unsuitable for bypass grafting.\n* Lack of available vascular material for grafting.\n* Porcelain aorta.",{"count":47,"type":20},50,"Prospective, single-center, clinical registry of patients with symptomatic\u002Fcritical carotid artery stenosis at risk of stroke coexisting with unstable or multivessel severe coronary artery disease and\u002For severe valvular heart disease undergoing endovascular treatment of carotid atherosclerosis using a mesh stent in combination with cardiac surgery (coronary artery bypass grafting (CABG) and\u002For valve surgery). A study involving clinical data evaluation of truly simultaneous treatment outcomes in patients deemed to require carotid revascularization at the time of surgical cardiac intervention (single-stage, simultaneous treatment). An open-label study, without randomization - a single arm study.\n\nAcademic Registry - scientific activity of the Faculty of Medicine, Collegium Medicum, Jagiellonian University and John Paul II Hospital.",[50,51,52,53,25],"Carotid Stenosis","Coronary Artery Disease","Valvular Heart Disease","Myocardial Infarction",[50,55,56,57,58],"Coronary Artery Disease, Valvular Disease","Heart Failure, Pulmonary Edema","Single Anesthesia","Simultaneous Procedure","2021-07-13",{"date":61,"type":30},"2021-07-22",{"date":63,"type":30},"2021-05-01",{"date":65,"type":20},"2027-05-01",{"name":67,"class":37},"John Paul II Hospital, Krakow",1]