[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"quality-improvement\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:quality-improvement":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,12,0,[8,42,76,104,134,181,205,226,253,281,309,347],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100624994","enhancing-operational-efficiency-in-eye-care-services-100624994",false,"NCT07416864","Enhancing Operational Efficiency in Eye Care Services","Enhancing Operational Efficiency in Eye Care Services: A Mixed-Methods Operational Research Study in a Tertiary Care Eye Hospital","Inclusion Criteria:\n\n* All patients undergoing pre-planned elective procedures in the unit listed on appointment basis.\n* Eligibility: Enrolment criteria: any patient undergoing any planned procedure is included on daily basis\n\nExclusion criteria:\n\n* Patients undergoing emergency procedures.\n* Data for patients whose procedures were cancelled\u002Fpostponed\n* Any other patients undergoing procedures under the free eye camps","ALL","85 Years",{"count":19,"type":20},400,"ESTIMATED","INTERVENTIONAL",[23],"NA","Pushpagiri Vitreo Retina Institute (PVRI) based in Secunderabad is a tertiary care eye hospital providing specialty eye care services since 2007. Over 15-20 preplanned surgical\u002Fclinical procedures are conducted for patients requiring care on a daily basis. They range from simple cataract surgeries or injections to detailed specialty surgeries including Vitreo-retina, glaucoma, pediatric eye care and muscular conditions of the eye. All procedures are elective procedures and are pre-planned. The current study aims to improve hospital efficiency and reduce the total appointment time for patients. The current study aims to reduce patient overall waiting time by 15-25% by introducing simple patient identification tools to help streamline all planned procedures.",[26,27,28],"Quality Improvement","Appointments and Schedules","Operations Research Workflow","RECRUITING","2026-04-29",{"date":32,"type":33},"2026-05-05","ACTUAL",{"date":35,"type":33},"2026-03-01",{"date":37,"type":20},"2026-12",{"name":39,"class":40},"Seva Canada Society","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":41},"100634385","optimizing-early-nutrition-management-of-extremely-andor-very-preterm-infants-100634385","NCT07538999","Optimizing Early Nutrition Management of Extremely and\u002For Very Preterm Infants","Optimizing Early Nutrition Management of Extremely and\u002For Very Preterm Infants Based on Best Clinical Practice: a Real Word Study","Inclusion Criteria for intervention group:\n\n* (1) Admitted to the Neonatal Department of Children's Hospital of Fudan University during the study period.\n* (2) Preterm infants with a gestational age \\\u003C 32 weeks or a birth weight \\\u003C 1500 g.\n* (3) Admitted to the study center within 24 hours after birth.\n* (4) Obtained informed consent from family members. Exclusion Criteria for intervention group\n* (1) Newborns with severe congenital diseases, severe congenital malformations, chromosomal abnormalities, or genetic metabolic diseases.\n* (2) Death or discharge within two weeks after birth.\n\nInclusion Criteria for control group:\n\n* (1) Admitted to the Neonatal Department of Children's Hospital of Fudan University from January 2025 to December 2025.\n* (2) Preterm infants with a gestational age \\\u003C 32 weeks or a birth weight \\\u003C 1500 g.\n* (3) Admitted to the study center within 24 hours after birth. Exclusion Criteria for control group\n* (1) Newborns with severe congenital diseases, severe congenital malformations, chromosomal abnormalities, or genetic metabolic diseases.\n* (2) Death or discharge within two weeks after birth.","1 Day",{"count":51,"type":20},200,[23],"A clinical quality improvement bundle on early nutrition supplementation is developed to improving the clinical outcomes (including growth, organ function, and neurodevelopment outcomes) of extremely and\u002For very preterm infants. This bundle consists of three aspects: individualized and precise human milk feeding, early enteral zinc supplementation, and routine parenteral carnitine supplementation.",[55,26,56],"Nutrition Intervention","Preterm Infant",[58,59,60,61,62,63,64,65],"preterm infants","nutrition","bundle","zinc supplementation","carnitine supplementation","growth","outcomes","human milk feeding","NOT_YET_RECRUITING","2026-04-13",{"date":69,"type":33},"2026-04-20",{"date":71,"type":20},"2026-04-01",{"date":73,"type":20},"2029-12-31",{"name":75,"class":40},"Children's Hospital of Fudan University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":21,"phases":87,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":41},"100470535","patients-and-families-improving-safety-in-hospitals-by-actively-reporting-experiences-100470535","NCT05407129","Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences","Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences (I-SHARE)","I-SHARE","Inclusion Criteria:\n\n* Patient\u002FFamily\u002FCaregiver who has been hospitalized on the study unit during the study period (within the past 24 hours) or hospital employee who works at the study sites\n* Participants speaking all languages are eligible\n\nExclusion Criteria:\n\n* Admitted awaiting inpatient psychiatric placement\n* In state custody\n* Admitted for greater than 24 hours\n* Same day discharge\n* Covid positive\n* Previously enrolled in I-SHARE\n* Airborne illness precautions",true,{"count":86,"type":20},656,[23],"Hospitals ineffectively examine the safety of their processes by relying on voluntary incident reporting (VIR) by clinical staff who are overworked and afraid to report. VIR captures only 1-10% of events, excludes patients and families, and underdetects events in vulnerable groups like patients with language barriers. Patients and families are vigilant partners in care who are adept at identifying errors and AEs. Failing to actively include patients and families in safety reporting and instead relying on flawed VIR presents an important missed opportunity to improve safety. To improve hospital safety, there is a critical need to coproduce (create in partnership with families) effective systems to identify uncaptured errors. Without this information, hospitals are impeded in their ability to improve patient safety. In partnership with diverse families, nurses, physicians, and hospital leaders, investigators created a multicomponent communication intervention to engage families of hospitalized children in safety reporting. The intervention includes 3 elements: (1) a multilingual mobile (email, text, and QR-code) reporting tool prompting families to share concerns and suggestions about safety, (2) family\u002Fstaff education, and (3) a process for sharing family reports with the unit and hospital so systemic issues can be addressed.",[90,91,92,93,94,26],"Family Reported Errors and Adverse Events","Health Disparities","Family Safety Reporting","Patient Safety","Voluntary Incident Reporting","2026-03-22",{"date":97,"type":33},"2026-03-24",{"date":99,"type":33},"2023-04-13",{"date":101,"type":20},"2028-10-28",{"name":103,"class":40},"Boston Children's Hospital",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":16,"minAge":111,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":21,"phases":114,"briefSummary":115,"conditions":116,"keywords":121,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":130,"leadSponsor":132,"locationsCount":41},"100626096","british-columbia-prescriber-feedback-program---antimicrobial-resistance-100626096","NCT07431190","British Columbia Prescriber Feedback Program - Antimicrobial Resistance","Building a National Framework to Combat Antimicrobial Resistance in Primary Care (CANBuild-AMR): Study Protocol for an Impact Evaluation of the British Columbia Prescriber Feedback Program","Practitioner Inclusion Criteria:\n\nRegistered in 2024 with the BC Medical Services Plan (MSP) with:\n\n* A valid MSP billing number;\n* Status of Salaried, Private Practice, Temporary Licence, or Post Graduate;\n* Prescribed \\>100 dispensed medications in 2024.\n\nExclusion Criteria:\n\n* Previously opted out of the Therapeutics Initiative Portrait program\n\nPatient Exclusion Criteria:\n\n* Age \\\u003C18 years at time of oral antibiotic dispensation;\n* Received PharmaCare benefits through the Palliative Care program at any time during the baseline or study period;\n* Hospitalized within 1 week prior to an antibiotic prescription at any time during the baseline or study period;\n* On chronic suppressive antibiotic therapy (≥90 days' supply of any antibiotic dispensed) during the baseline or study period","18 Years",{"count":113,"type":20},7626,[23],"The goal of this study is to evaluate an educational intervention that aims to reduce the number of unnecessary antibiotics prescribed by family physicians and nurse practitioners in British Columbia, Canada.\n\nThe intervention materials include a confidential personalized prescribing \"portrait\" and an evidence-based educational summary (therapeutics letter), accompanied by an introduction letter.\n\nThe main research questions are:\n\n1. Will the intervention lead to a reduction in the overall number of antibiotics prescriptions started?\n2. Will the intervention lead to a reduction in the proportion of antibiotics prescribed that are likely unnecessary, especially prescriptions for upper respiratory tract infections, acute bronchitis, acute sinusitis?\n\nResearchers will conduct an intervention study with family physicians and nurse practitioners in British Columbia, Canada. Participant clinicians will be randomly assigned to one of two groups. The Early Group will consist of 80% of the participants and will receive the intervention (prescribing portrait, evidence summary, and introduction letter) at the start of the study. The Delayed Group will consist of 20% of participants and will receive the intervention about nine months later. This study design allows most practitioners to receive the intervention early while still allowing time to compare the two groups to assess the impact. To estimate the impact of the intervention, researchers will use administrative health data to compare the prescribing of the Early Group with prescribing of the Delayed Group.",[26,117,118,119,120],"Feedback","Prescribing","Antibiotics","Antimicrobial Drug Resistance",[122,123,124,119,125],"Randomized controlled trial","Prescribing feedback","Quality improvement","Antimicrobial resistance","2026-02-17",{"date":128,"type":33},"2026-02-24",{"date":126,"type":20},{"date":131,"type":20},"2028-11-30",{"name":133,"class":40},"University of British Columbia",{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":142,"targetDuration":4,"studyType":21,"phases":144,"briefSummary":145,"conditions":146,"keywords":160,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":41},"100620350","enhancing-mental-and-physical-health-of-women-veterans-30-100620350","NCT07356479","Enhancing Mental and Physical Health of Women Veterans 3.0","Enhancing Mental and Physical Health of Women Through Engagement and Retention (EMPOWER) 3.0 (QUE 25-015)","EMPOWER","Inclusion Criteria:\n\n* This study is recruiting VA sites - not individual patients.\n* Prior to randomization, the study team will work with sites to ensure they have met the preconditions necessary to enroll in the study, which includes VISN, regional and\u002For facility level leadership support for participation.\n\nExclusion Criteria:\n\n* N\u002FA",{"count":143,"type":20},18,[23],"Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able to use those services. Furthermore, few VA improvement efforts have focused on women Veterans' health and health care in midlife. The EMPOWER QUERI 3.0 Program is a cluster randomized type 3 hybrid implementation-effectiveness trial testing two strategies designed to support implementation and sustainment of evidence-based practices for women Veterans in at least 18 VA facilities from 4 regions.",[147,148,149,150,151,152,153,154,155,156,157,158,159,26],"Cardiovascular Diseases","Overweight","Obesity","Hypertension","Cholesterol","Diabetes Mellitus","Prediabetic State","Menopause","Cognitive Behavioral Therapy","Primary Health Care","Stress Disorders, Post-Traumatic","Prevention","Implementation Science",[161,148,149,150,151,152,153,154,155,156,157,158,162,26,163,164,165,166,167,168,169,170],"Cardiovascular diseases","Implementation science","Women","Veterans","Patient Participation","Patient Satisfaction","Patient Preference","Physicians, Primary Care","Physicians, Women","Health Behavior","2026-01-12",{"date":173,"type":33},"2026-01-21",{"date":175,"type":20},"2026-10-01",{"date":177,"type":20},"2031-09-30",{"name":179,"class":180},"VA Office of Research and Development","FED",{"id":182,"slug":183,"hasResults":11,"nctId":184,"briefTitle":185,"officialTitle":186,"acronym":4,"eligibilityCriteria":187,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":188,"targetDuration":4,"studyType":21,"phases":190,"briefSummary":191,"conditions":192,"keywords":196,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":197,"lastUpdatePostDateStruct":198,"startDateStruct":200,"completionDateStruct":202,"leadSponsor":204,"locationsCount":41},"100617380","impact-evaluation-of-the-therapeutic-initiatives-prescribing-portrait-and-therapeutics-letter-on-opioid-use-by-dentists-100617380","NCT07317869","Impact Evaluation of the Therapeutic Initiative's Prescribing Portrait and Therapeutics Letter on Opioid Use by Dentists","Impact Evaluation of the Therapeutic Initiative's Prescribing Portrait and Therapeutics Letter on Opioid Use by Dentists for Dental Pain","Inclusion Criteria:\n\nDentists will be eligible to receive an individual prescribing Portrait if they meet all of the following criteria:\n\n* Registered with the British Columbia Medical Services Plan (MSP) as being in active practice;\n* Have a valid mailing address in British Columbia; and\n* Issued ≥10 prescriptions dispensed at community pharmacies between January 5, 2025 and January 5, 2026, as identified in PharmaNet claims data.\n\nPatients will be eligible for inclusion if they meet all of the following criteria:\n\n* Received an opioid prescription from an eligible dentist during the study period (January 6, 2026 to January 6, 2027);\n* The opioid prescription was issued by a dentist; and\n* Were continuously enrolled in the British Columbia Medical Services Plan (MSP) during the 12 months prior to the opioid prescription.\n\nExclusion Criteria:\n\nPatients will be excluded if they meet any of the following criteria:\n\n* Had a medication dispensed under Plan P in the 12 months prior to the opioid prescription; or\n* Filled a prescription for opioid agonist therapy (OAT) within 180 days prior to the opioid prescription.",{"count":189,"type":20},3498,[23],"The aim of this study is to estimate the impact of providing personalized prescribing data and educational materials on opioid prescribing to dentists in British Columbia, Canada.\n\nThe main research questions are:\n\n1. What is the impact of an intervention on the use of opioids for dental pain? The intervention includes a personalized prescribing report (a \"Portrait\"), brief educational summary, and patient education materials; and\n2. Does the impact of the intervention increase when dentists are also invited to attend facilitated audit-and-feedback group sessions and to develop a practice improvement plan? Using administrative health data, the prescribing of those in different combinations of materials in the Early Group will be compared to those in the Delayed Group to estimate the impact of the materials on prescribing by the dentists.",[193,26,194,195],"Clinical Audit","Opioid","Dentistry",[122,123,124,194],"2026-01-05",{"date":199,"type":33},"2026-01-08",{"date":201,"type":20},"2026-01-06",{"date":203,"type":20},"2028-01-31",{"name":133,"class":40},{"id":206,"slug":207,"hasResults":11,"nctId":208,"briefTitle":209,"officialTitle":210,"acronym":4,"eligibilityCriteria":211,"healthyVolunteers":11,"sex":16,"minAge":111,"maxAge":4,"enrollmentInfo":212,"targetDuration":4,"studyType":213,"phases":4,"briefSummary":214,"conditions":215,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":217,"lastUpdatePostDateStruct":218,"startDateStruct":220,"completionDateStruct":222,"leadSponsor":224,"locationsCount":41},"100428072","introduction-of-an-operating-room-black-box-to-identify-analyse-and-prevent-errors-in-the-vascular-hybrid-room-100428072","NCT04854278","Introduction of an Operating Room Black Box to Identify, Analyse and Prevent Errors in the Vascular Hybrid Room","Development of Strategies to Identify, Analyse and Prevent Errors in the Vascular Hybrid Room - an Inter-professional Approach to Enhance Technical and Non-technical Performance and to Improve Patient Safety","Inclusion Criteria:\n\n* Patients undergoing elective (planned more than 48 hours) endovascular procedures.\n* Symptomatic aortic-iliac-femoral-popliteal-below the knee atherosclerotic stenotic or occlusive disease (PVI)\n* Endovascular exclusion of thoracic aortic, infrarenal abdominal aortic and\u002For iliac aneurysm repair (EVAR)\n\nExclusion Criteria:\n\n* No consent of patient\n* No consent of all endovascular team members\n* Emergency procedure (planned \\\u003C 48h before)\n* Endovascular procedure not treating atherosclerotic aortic-iliac-femoral-popliteal-below the knee disease or aortic-iliac aneurysm",{"count":19,"type":20},"OBSERVATIONAL","The \"OR Black box\", an inclusive multiport data capturing system has been developed and successfully used for detailed analysis of laparoscopic surgical procedures. A pilot study has shown that this system can be successfully installed in the hybrid room at Ghent University Hospital and used for detailed analysis of intra-operative errors and radiation safety issues in endovascular procedures.\n\nSecondary analysis of pilot study data via direct video coding assessed the relationship between leadership style of the surgeon and team behavior and possible fluctuations during surgery.\n\nThis novel approach allows a prospective objective assessment of human and environmental factors as well as measurement of errors, events and outcomes. In this study, the aim is to use the acquired knowledge to characterize a chain of events, identify high-risk interventions and identify areas for improvement, both on an organizational, team or individual level.\n\nHypothesis: non-technical skills, environmental factors and teamwork in the hybrid room correlate with surgical technical performance and error rates. Furthermore, we hypothesize that incidents and adverse events can be tracked to a chain of errors that is influenced by technical and non-technical skills as well as environmental factors.",[93,216,26],"Endovascular Procedures","2025-12-15",{"date":219,"type":33},"2025-12-22",{"date":221,"type":33},"2019-02-19",{"date":223,"type":20},"2027-12-31",{"name":225,"class":40},"University Ghent",{"id":227,"slug":228,"hasResults":11,"nctId":229,"briefTitle":230,"officialTitle":231,"acronym":4,"eligibilityCriteria":232,"healthyVolunteers":84,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":233,"targetDuration":4,"studyType":21,"phases":235,"briefSummary":236,"conditions":237,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":245,"startDateStruct":247,"completionDateStruct":249,"leadSponsor":251,"locationsCount":41},"100522674","multicenter-clinical-translational-study-of-icu-no-crbsi-based-on-improvement-science-100522674","NCT06085690","Multicenter Clinical Translational Study of \"ICU-NO CRBSI\" Based on Improvement Science","A Multicenter Clinical Translational Study of \"ICU-NO CRBSI\" Based on Improvement Science in China","Inclusion Criteria:\n\n* ICU stay over 48 hours\n* CVC was placed for more than 24 hours\n\nExclusion Criteria:\n\n* Pregnant patients\n* Patients with a history of CRBSI infection\n* Patients with central venous catheterization were brought in from other hospitals",{"count":234,"type":20},8050,[23],"The goal of this type of study is to construct the continuous quality promotion project \"ICU-NO CRBSI(Catheter-Related Bloodstream Infection , CRBSI)\" based on improvement science, and to verify its effect in the prevention of central venous catheter-related bloodstream infection and continuous quality improvement in ICU ( Intensive Care Unit , ICU) through multi-center implementation and two rounds of improvement.\n\nThe main question\\[s\\] it aims to answer are:\n\nWhat is the incidence of catheter-related bloodstream infection in the ICU of participating units? How compliant are health care providers in the ICU with evidence-based sensory control practices for the prevention of catheter-associated bloodstream infection?\n\nParticipants will be provided with the hospital's routine CVC (Central Venous Catheter ,CVC) care practices and CVC quality improvement measures based on evidence-based guidelines What technical and cultural support is needed to implement quality and safety improvement measures?",[238,239,240,241,242,243,26],"CRBSI - Catheter Related Bloodstream Infection","Evidence-based Nursing Practice","Central Venous Catheter Related Bloodstream Infection","Central Venous Catheter Associated Bloodstream Infection","Central Line Infection","CLABSI - Central Line Associated Bloodstream Infection","2025-11-14",{"date":246,"type":33},"2025-11-17",{"date":248,"type":33},"2023-09-04",{"date":250,"type":20},"2025-12-31",{"name":252,"class":40},"Fudan University",{"id":254,"slug":255,"hasResults":11,"nctId":256,"briefTitle":257,"officialTitle":258,"acronym":4,"eligibilityCriteria":259,"healthyVolunteers":11,"sex":16,"minAge":260,"maxAge":4,"enrollmentInfo":261,"targetDuration":4,"studyType":21,"phases":263,"briefSummary":264,"conditions":265,"keywords":270,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":272,"lastUpdatePostDateStruct":273,"startDateStruct":275,"completionDateStruct":277,"leadSponsor":279,"locationsCount":41},"100378717","chips-vte-study-in-hospitalized-patients-to-prevent-hospital-acquired-venous-thromboembolism-100378717","NCT04211181","CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism","Effect on Thromboprophylaxis Among Hospitalized Patients Using a System-wide Multifaceted Quality Improvement Intervention: Rationale and Design for a Multicenter Cluster Randomized Clinical Trial in China","Inclusion Criteria:\n\n1. Aged ≥14 years\n2. Have an expected hospital stay ≥72 hours for medical and\u002For surgical treatment\n3. Written informed consent\n\nExclusion Criteria:\n\n1. Inability to be followed-up at until 3 months after randomization\n2. Have participated in similar trials or are undergoing other clinical trials\n3. Refuse or are unable to give informed consent\n4. VTE identified on CTPA or lower extremity vein ultrasound at or any time before enrollment\n5. Requiring a full dose of anticoagulant treatment (e.g., recent VTE, atrial fibrillation).","14 Years",{"count":262,"type":20},5800,[23],"Although pharmacologic and mechanical methods to prevent VTE are safe, effective, cost-effective, and advocated by authoritative guidelines,many studies continue to demonstrate that these preventive methods are significantly underutilized, especially in China.A number of quality improvements (QI) program have been established in several countries or hospitals.However,no exit effective protocol has been demonstrated well enough or adequate to drive breakthrough levels of improvement. A reliable and practical QI that can support hospitals or physicians in China is warranted.To evaluate the multifaceted quality improvement intervention effect in clinical setting, we will conduct a cluster-randomized clinical trial among China PUlmonary Thromboembolism REgistry Study (CURES) group, aiming to test whether it's applicable to real-world practice in China.\n\nA multicenter, two-arms, open-label clinical trial has been designed to determine whether the system-wide multifaceted intervention could increase the rate of at-risk participants who received prophylaxis (RP) and decrease the incidence of any hospital-associated VTE in 90 days during and after hospital admission. .Selected hospital will be regarded as a cluster and randomized into interventional or control group.In interventional group, eligible hospitalized patients will receive a variety of the multifaceted quality improvement(QI) interventions since admitted in hospital.In control group, patients will receive no more than common recommended care or an existing policy.The primary outcomes are the proportion of appropriate prophylaxis in hospitalized patients and the incidence of HA-VTE in 90 days after hospital admission.",[266,267,268,269,26],"Venous Thromboembolic Disease","Pulmonary Embolism","Venous Thromboembolism","Deep Venous Thrombosis",[124,268,271],"Hospital Associated-VTE","2025-09-11",{"date":274,"type":33},"2025-09-17",{"date":276,"type":33},"2025-08-01",{"date":278,"type":20},"2026-12-31",{"name":280,"class":40},"China-Japan Friendship Hospital",{"id":282,"slug":283,"hasResults":11,"nctId":284,"briefTitle":285,"officialTitle":286,"acronym":4,"eligibilityCriteria":287,"healthyVolunteers":11,"sex":288,"minAge":4,"maxAge":4,"enrollmentInfo":289,"targetDuration":4,"studyType":213,"phases":4,"briefSummary":291,"conditions":292,"keywords":296,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":300,"lastUpdatePostDateStruct":301,"startDateStruct":303,"completionDateStruct":305,"leadSponsor":307,"locationsCount":41},"100570029","the-impact-of-fasting-duration-on-quality-of-recovery-after-cesarean-section-100570029","NCT06701929","The Impact of Fasting Duration on Quality of Recovery After Cesarean Section","How Fasting Duration Before Cesarean Section Affects the Quality of Recovery Score (ObsQoR-11)","Inclusion Criteria:\n\n* Presenting for elective c-section under spinal anesthesia\n\nExclusion Criteria:\n\n* Unable to communicate in French or English\n* Urgent c-section\n* Planned general anesthesia","FEMALE",{"count":290,"type":20},100,"This study will evaluate the effect of fasting duration and elective c-section start time on the overall quality of recovery. Patients will be seen 24 hours after surgery to answer 11 questions on their overall recovery after surgery. Several factors will be tracked to determine their effect on recovery, with the primary variable of interesting",[26,293,294,295],"Quality of Recovery From Anaesthesia","Cesarean Section","Fasting ( 6H for Solid ; 2H for Clear Fluid )",[297,298,299],"Quality of Recovery","cesarean section","fasting duration","2025-08-27",{"date":302,"type":33},"2025-09-04",{"date":304,"type":33},"2025-03-18",{"date":306,"type":20},"2026-06-01",{"name":308,"class":40},"Jewish General Hospital",{"id":310,"slug":311,"hasResults":11,"nctId":312,"briefTitle":313,"officialTitle":314,"acronym":315,"eligibilityCriteria":316,"healthyVolunteers":11,"sex":16,"minAge":111,"maxAge":4,"enrollmentInfo":317,"targetDuration":4,"studyType":213,"phases":4,"briefSummary":319,"conditions":320,"keywords":328,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":338,"lastUpdatePostDateStruct":339,"startDateStruct":341,"completionDateStruct":343,"leadSponsor":345,"locationsCount":41},"100572802","national-emergency-bariatric-surgery-audit-100572802","NCT06738004","National Emergency Bariatric Surgery Audit","A National Multi-centre Prospective Audit of Unplanned Surgical and Endoscopic Interventions in Patients Who Have Undergone Bariatric Surgery in the UK or Abroad","NEBSA","Inclusion Criteria:\n\n* Admissions from i) the emergency department, clinic, urgent care or primary care to the bariatric surgical team as an emergency; ii) from an inpatient team as an urgent referral; iii) a return to theatre following an elective bariatric procedure; iv) another hospital via patient transfer to a specialised unit.\n* Participants undergoing any intervention or procedure to treat or diagnose bariatric complications, (e.g., OGDs, interventional radiology, surgery, supplemental enteral or parenteral nutrition).\n\nExclusion Criteria:\n\n* age \\\u003C18 years old\n* have a length of stay \\\u003C24 hrs.\n* initial diagnosis of BSE is changed or if their readmission is found to be unrelated to previous bariatric surgery.",{"count":318,"type":20},500,"The goal of this observational study is to investigate the incidence, management, and outcomes of complications following bariatric surgery in patients in the United Kingdom. The main questions it aims to answer are:\n\n* What is the prevalence of unplanned interventions due to complications following bariatric surgery in the UK?\n* What are the current practices for managing these complications, and how do they impact patient outcomes?\n\nParticipants will:\n\nBe identified from hospitals treating patients presenting with complications following bariatric surgery.\n\nHave their data collected regarding demographics, surgical history, complications, treatments, and outcomes.\n\nResearchers will compare different management strategies and their impact on patient outcomes, with the aim of identifying best practices to improve emergency bariatric care and factors leading to patients attending as an emergency.",[321,322,323,324,325,26,326,327],"Bariatric Surgery","Postoperative Complications","Emergencies","Surgical Procedures, Operative","Outcome Assessment (Health Care)","Morbidity","Mortality",[329,330,331,332,333,334,335,124,336,337],"Bariatric surgery","Emergency complications","National audit","Surgical outcomes","Management strategies","United Kingdom","Patient safety","Morbidity and mortality","Postoperative complications","2024-12-12",{"date":340,"type":33},"2024-12-17",{"date":342,"type":33},"2023-11-09",{"date":344,"type":20},"2025-12-09",{"name":346,"class":40},"Bedfordshire Hospitals NHS Foundation Trust",{"id":348,"slug":349,"hasResults":11,"nctId":350,"briefTitle":351,"officialTitle":352,"acronym":353,"eligibilityCriteria":354,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":355,"targetDuration":4,"studyType":21,"phases":357,"briefSummary":358,"conditions":359,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":361,"lastUpdatePostDateStruct":362,"startDateStruct":364,"completionDateStruct":366,"leadSponsor":368,"locationsCount":41},"100570888","study-to-evaluate-the-impact-of-the-recovery-pathway-on-postoperative-leght-of-stay-in-coronary-artery-bypass-surgery-100570888","NCT06713096","Study to Evaluate the Impact of the Recovery Pathway on Postoperative Leght of Stay in Coronary Artery Bypass Surgery","Prospective and Randomized Study to Evaluate the Impact of the Recovery Pathway on Postoperative Leght of Stay in Coronary Artery Bypass Surgery","KAMAY","Inclusion Criteria:\n\n* Adult patients (\\>18 years old)\n* Undergoing isolated coronary artery bypass grafting (CABG) with elective or urgent status\n* Signed informed consent form (ICF)\n\nExclusion Criteria:\n\n* Emergency patients\n* Severe ventricular dysfunction (ejection fraction \\\u003C30%)\n* Renal impairment (creatinine clearance \\\u003C30 mL\u002Fmin)\n* Atrial fibrillation or need for oral anticoagulation\n* Moderate-to-severe anemia (hematocrit \\\u003C32%)\n* STS risk score \\>4%\n* Patient and\u002For family disagreement with the protocol\n* Failure to sign the informed consent form",{"count":356,"type":20},128,[23],"This randomized and prospective trial aims to evaluate the implementation of a rapid recovery protocol for coronary artery bypass grafting (CABG) in a hospital serving patients from the Brazilian Unified Health System (Sistema Único de Saúde - SUS). The study will compare outcomes between two groups: patients receiving care under the rapid recovery protocol and those following the standard institutional care.\n\nPrimary Objective:\n\nCompare postoperative hospital stay between the rapid recovery group and the usual care group.\n\nSecondary Objectives:\n\nAssess morbidity and mortality between both groups.\n\nEvaluate patient satisfaction using validated tools.\n\nAnalyze incremental costs associated with both approaches.\n\nAssess healthcare teams' learning progression regarding the protocol (Kirkpatrick method).\n\nEvaluate adherence to rapid recovery protocol metrics by healthcare teams.\n\nMeasure changes in patient safety culture among healthcare professionals.\n\nHypothesis:\n\nThe null hypothesis assumes no difference in hospital stay between the two groups. The alternative hypothesis suggests that the rapid recovery protocol will reduce hospital stay compared to the standard care. Previous findings from Mejia et al. (2022) indicated a 40% reduction in postoperative hospital stay (from 13 to 7.8 days) for cardiac surgery patients under a rapid recovery protocol at the Heart Institute (InCor HCFMUSP).\n\nThis trial will provide critical insights into the applicability of enhanced recovery after surgery (ERAS) principles in cardiac surgery within the context of public healthcare, aiming to improve outcomes and optimize resource use.",[360,26],"Enhanced Recovery After Surgery","2024-11-26",{"date":363,"type":33},"2024-12-03",{"date":365,"type":33},"2021-11-25",{"date":367,"type":20},"2025-12",{"name":369,"class":40},"University of Sao Paulo General Hospital"]