[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"quality-of-recovery-qor-15\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:quality-of-recovery-qor-15":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,50,79,110,138,161,200,224],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100632151","effect-of-preoperative-erector-spinae-plane-block-on-recovery-quality-time-to-return-to-daily-activities-and-postoperative-pain-scores-in-inguinal-hernia-surgery-100632151",false,"NCT07509957","Effect of Preoperative Erector Spinae Plane Block on Recovery Quality, Time to Return to Daily Activities, and Postoperative Pain Scores in Inguinal Hernia Surgery","ESPB for IHR","Inclusion Criteria:\n\n1. Patients aged between 18 and 65 years\n2. Patients scheduled to undergo open IHT surgery under spinal anesthesia (unilateral)\n3. Both male and female patients\n\nExclusion Criteria:\n\n1. Patients with coagulation disorders\n2. Patients with chronic opioid use\n3. Patients who develop intraoperative complications\n4. Patients with a preoperative Numeric Rating Scale (NRS) pain score ≥4\n5. Patients with a history of revision (recurrent) surgery\n6. Patients unable to communicate for any reason\n7. Patients who decline to participate in the study","ALL","18 Years","65 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate the effect of the erector spinae plane block (ESPB), performed after surgery, on quality of recovery, postoperative pain, and time to return to daily activities in patients undergoing open inguinal hernia repair under spinal anesthesia.\n\nPostoperative pain following inguinal hernia surgery may delay recovery and negatively affect patients' return to normal daily life. Although ESPB has been widely used as an effective analgesic technique in various surgical procedures, its effectiveness in inguinal hernia repair remains limited and not well established.\n\nIn this randomized controlled study, patients will be divided into two groups: one group will receive ESPB after surgery, while the control group will not receive any block. All patients will receive standard postoperative analgesia.\n\nQuality of recovery, acute pain scores, and analgesic consumption will be assessed within the first 24 hours after surgery, and return to daily activities will be evaluated 30 days after surgery.\n\nThe primary outcome of this study is quality of recovery assessed using the Quality of Recovery-15 (QoR-15) questionnaire. QoR-15 scores range from 0 to 150, with higher scores indicating better recovery. Scores will be recorded preoperatively and 24 hours after surgery.\n\nSecondary outcomes include postoperative pain intensity, total opioid consumption, and time to return to daily activities. Pain intensity will be assessed using the Numeric Rating Scale (NRS), where 0 indicates no pain and 10 indicates the worst pain imaginable, at 15, 30, 60, and 120 minutes, as well as 6, 12, and 24 hours after surgery.\n\nTotal opioid consumption will be determined by recording the cumulative dose of intravenous tramadol administered as rescue analgesia within the first 24 hours after surgery. Time to return to daily activities will be evaluated via telephone follow-up 30 days after surgery.",[27,28,29,30,31],"Inguinal Hernia Unilateral","Erector Spinae Plane Block","Quality of Recovery (QoR-15)","Numeric Rating Scale","Return to Daily Activity",[33,28,34,35,31,36],"Inguinal Hernia Repair","Regionel Anesthesia","Quality of Recovery","Postoperative Pain","RECRUITING","2026-07-01",{"date":40,"type":41},"2026-07-02","ACTUAL",{"date":43,"type":41},"2026-04-04",{"date":45,"type":21},"2026-07-16",{"name":47,"class":48},"Sanliurfa Education and Research Hospital","OTHER_GOV",2,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":57,"minAge":17,"maxAge":18,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":78},"100641608","subtransverse-interligamentary-block-versus-paravertebral-block-for-quality-of-recovery-after-mastectomy-100641608","NCT07647367","Subtransverse Interligamentary Block Versus Paravertebral Block for Quality of Recovery After Mastectomy","Ultrasound-Guided Subtransverse Interligamentary Plane Block Versus Thoracic Paravertebral Block for Quality of Recovery After Modified Radical Mastectomy: A Randomized Non-Inferiority Trial","Inclusion Criteria:\n\n* Adult female patients aged 18 to 65 years with American Society of Anesthesiologists (ASA) Physical Status I - III, who were scheduled for unilateral MRM surgery under general anesthesia and able to understand and complete the QoR-15 questionnaire\n\nExclusion Criteria:\n\n* • Patients declined to participate in the trial.\n\n  * History of allergy to the used local anesthetic (LA) drugs.\n  * Patients with cutaneous lesions at the needle entry point.\n  * Coagulopathy or current anticoagulant therapy contraindicating regional block.\n  * Patients with severe hepatic, renal, cardiac, or respiratory disease.\n  * Psychiatric or cognitive disorder interfering with QoR-15 assessment\n  * Chronic opioid use or chronic pain syndrome.\n  * Failed block.\n  * Morbid obesity (body mass index \\>40 kg\u002Fm2)\n  * Intraoperative major complications requiring postoperative ICU admission.\n  * Pregnancy","FEMALE",{"count":20,"type":21},[24],"This prospective randomized controlled double blinded non-inferiority study will be carried out in Tanta University Hospitals for duration of 6 months from June 2026 to December 2026 on 60 female patients scheduled for unilatral modified radical mastectomy under general anesthesia.",[29,62],"Modified Radical Mastectomy",[64,65,66],"subtransverse interligamentary plane block","modified radical mastectomy","quality of recovery","NOT_YET_RECRUITING","2026-06-14",{"date":70,"type":41},"2026-06-17",{"date":72,"type":21},"2026-06",{"date":74,"type":21},"2027-01",{"name":76,"class":77},"Tanta University","OTHER",1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":57,"minAge":17,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":89,"briefSummary":91,"conditions":92,"keywords":97,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":4},"100633586","phase-2-mag-pain---magnesium-for-postoperative-analgesia-in-the-newly-delivered-100633586","NCT07528612","MAG-PAIN - MAGnesium for Postoperative Analgesia In the Newly Delivered","Effect of Intravenous Magnesiumsulfate on Postoperative Pain in Patients Undergoing Cesarean Section: The Magnesium for Postoperative Analgesia In the Newly Delivered, The MAG-PAIN Randomized Controlled Trial.","MAG-PAIN","Inclusion Criteria:\n\n* Adult\n* Planned or non-urgent c-section in regional anesthesia\n* Ability to read, speak and understand infromation in Swedish\n* Oral and written consent\n\nExclusion Criteria:\n\n* Contraindications for spinal anesthesia\n* Moderate to severe kidney failure\n* Need of translator\n* Ongoing treatment with magnesium-infusion\n* Myastenia Gravis",{"count":88,"type":21},150,[90],"PHASE2","The study aims to investigate whether a commonly used medicine, magnesium, can help reduce pain after a Caesarean section. A total of 150 participants will be included. Their usual medical care will not change, and participation is entirely voluntary. The purpose of the study is to determine whether magnesium can improve pain relief after surgery and support faster recovery and bonding with the newborn.\n\nBefore the operation, potential participants will receive a text message containing a short questionnaire about their background and their expectations regarding postoperative pain. On the day of surgery, all patients will receive two intravenous lines as part of routine care. Those who participate in the study will be asked to rate how painful this insertion was on a scale from one to ten. The participants will then be randomly assigned to receive either magnesium or a saltwater solution through a 100 ml drip, which is administered after the baby is born. Neither participants nor the clinical staff will know which solution has been given, and no blood samples will be collected. After the procedure, participants will be asked several times about their pain level.\n\nDuring the first three days after the operation, each participant will receive one text message per day with a short questionnaire about their pain, general recovery, and early bonding with their newborn. Fourteen days after the operation, and again three months later, they will receive additional questionnaires similar to the earlier ones. Each questionnaire takes approximately five to seven minutes to complete, and no extra hospital visits are required.\n\nMagnesium can cause side effects, but the risks associated with the dose used in the study are low. The most common side effect is a brief burning sensation at the infusion site, which is not harmful. Magnesium is widely used in medical care, including in pregnant patients, and the study team considers the treatment safe. Because the medication is administered after birth, it does not affect the baby and does not increase risks during breastfeeding.\n\nAll collected information will be handled securely and confidentially. Data will be coded so that individual participants cannot be directly identified, and only the research team will have access to the key linking codes to individuals. Participants have the right to access their data, request corrections, ask for deletion of their information, or limit how their data is used. The study has been approved by the Swedish Ethical Review Authority, and results will be published in a scientific journal without identifying any participant. No financial compensation is provided, but participants are covered by the usual patient and medication insurance.\n\nTo ensure that the study is conducted correctly, authorized monitors or authorities may compare study data with medical records. These individuals must sign confidentiality agreements. By giving consent to participate, individuals allow this review. All data will be stored according to legal archiving requirements.\n\nParticipation in the study is completely voluntary. Individuals may withdraw at any time, and if they do, their collected data will be deleted. Their medical care before, during, and after the operation will not be affected by their decision to participate or withdraw.",[36,29,93,94,95,96],"Pain Prediction","Magnesium Sulfate","Pain Interference","Self-Efficacy",[98,99,100],"Postoperative pain after Caesarean section","Postoperative core outcome set for postoperative pain","NMDA-antagonism","2026-04-14",{"date":103,"type":41},"2026-04-17",{"date":105,"type":21},"2026-04-02",{"date":107,"type":21},"2028-12-31",{"name":109,"class":77},"Region Halland",{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":22,"phases":120,"briefSummary":122,"conditions":123,"keywords":128,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":131,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":49},"100607290","phase-4-perioperative-medicine-platform-trial-100607290","NCT07186634","PeRiOperative Medicine Platform Trial","Domain-Specific Appendix: OXYGEN","PROMPT","PROMPT - Inclusion Criteria:\n\n* Adult patient (≥18 years of age at time of admission)\n* Scheduled to undergo a surgical procedure involving a skin incision, with an expected duration of at least 2 hours, and a planned overnight hospital stay of at least 1 night (including, but not limited to, cardiac surgery, orthopedic surgery, obstetric, or gynecological surgery).\n\nPROMPT - Exclusion Criteria:\n\n* ASA physical status 5 (moribund, not expected to survive with or without an operation)\n* Inability to provide informed consent\n* Previous participation in PROMPT within the prior 30 days.\n\nDSA 02 - PROMPT - Exclusion Criteria:\n\n* ASA physical status 1 or 2\n* Undergoing cardiac surgery\n* Undergoing thoracic surgery if one-lung ventilation is required\n* Currently suspected or proven infection\n* Advanced lung disease requiring home oxygen therapy\n* Previous bleomycin therapy\n* Known or suspected pregnancy",{"count":119,"type":21},7800,[121],"PHASE4","Our specific aims are to investigate whether conservative (≤30%), intermediate (50%), or liberal (80%) inspired oxygen during and immediately after surgery: Aim 1: Reduces surgical site infections (SSIs or \"wound infections\") and other healthcare-associated infections (pneumonia and sepsis). Aim 2: Reduces a pooled composite of serious postoperative complications, leading to a faster and more complete recovery after surgery, and thus increases \"days alive and at home up to 30 days after surgery\" (DAH30). Primary hypothesis: Liberal (80%) oxygen concentration delivered with anesthesia in patients undergoing major surgery reduces the incidence of SSIs after surgery compared to conservative (≤30%) or intermediate (50%) oxygen concentration. Secondary hypothesis: Hyperoxia (50-80%) delivered with anesthesia in patients undergoing major surgery increases the incidence of pulmonary and other complications after surgery compared to conservative (≤30%) oxygen concentration, resulting in fewer Days At Home (DAH). PROMPT enrolls patients undergoing elective or semi-elective surgery.",[124,125,126,29,127],"Surgical Site Infection After Major Surgery","Anaesthesia","Major Complications","Quality of Life",[129,130],"Anaesthesiology, complications, oxygen, surgery","platform trial",{"date":103,"type":41},{"date":133,"type":41},"2026-04-06",{"date":135,"type":21},"2035-12",{"name":137,"class":77},"Monash University",{"id":139,"slug":140,"hasResults":11,"nctId":141,"briefTitle":142,"officialTitle":143,"acronym":4,"eligibilityCriteria":144,"healthyVolunteers":11,"sex":16,"minAge":145,"maxAge":18,"enrollmentInfo":146,"targetDuration":4,"studyType":22,"phases":148,"briefSummary":149,"conditions":150,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":156,"completionDateStruct":157,"leadSponsor":159,"locationsCount":78},"100628782","comparison-of-two-sitting-durations-during-saddle-anesthesia-on-discharge-readiness-in-perianal-surgery-100628782","NCT07466121","Comparison of Two Sitting Durations During Saddle Anesthesia on Discharge Readiness in Perianal Surgery","Comparison of Two Sitting Durations During Saddle Anesthesia on Discharge Readiness in Perianal Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patients (21-65 years), ASA I-III undergoing perianal surgery.\n\nExclusion Criteria:\n\n* Severe cardiac morbidities (impaired contractility with ejection fraction \\\u003C 40%, heart block, arrhythmias, tight valvular lesions)\n* Contraindication to neuraxial anesthesia such as coagulopathy and local infection\n* Pregnant or lactating women,\n* Allergy of any of the study drugs","21 Years",{"count":147,"type":21},62,[24],"Most minor perianal surgeries are performed as day-case procedures requiring rapid recovery and effective symptom control. Saddle block anesthesia (SBA) provides reliable perineal anesthesia with minimal hemodynamic and motor effects, promoting faster recovery than general anesthesia. However, the duration of sitting after intrathecal injection influences anesthetic spread, and the optimal sitting time to balance adequate anesthesia with early discharge remains unclear.",[151,152,29],"Saddle Block Anesthesia","Readiness of Discharge","2026-03-15",{"date":155,"type":41},"2026-03-17",{"date":153,"type":41},{"date":158,"type":21},"2026-07",{"name":160,"class":77},"Cairo University",{"id":162,"slug":163,"hasResults":11,"nctId":164,"briefTitle":165,"officialTitle":166,"acronym":4,"eligibilityCriteria":167,"healthyVolunteers":168,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":169,"targetDuration":4,"studyType":22,"phases":171,"briefSummary":172,"conditions":173,"keywords":186,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":196,"leadSponsor":198,"locationsCount":4},"100628685","feasibility-of-breathwork-intervention-with-older-adults-after-knee-surgery-100628685","NCT07464860","Feasibility of Breathwork Intervention With Older Adults After Knee Surgery","A Box Breathing Intervention and the Surgical Stress Response in Older Adults Undergoing Total Knee Arthroplasty: A Randomized Controlled Feasibility Trial","Adults aged 65 years or older of any sex, gender and ethnic background who meet the following criteria will be eligible to enroll in the present study:\n\nInclusion Criteria:\n\n* scheduled for elective TKA within the next week to two months (can be second knee, but cannot be a revision of the original knee)\n* self-reported good health, including denial of debilitating illness that may affect participation in or be potentially exacerbated by deep, controlled breathing (i.e., chronic obstructive pulmonary disorder \\[COPD\\], symptomatic or advanced heart failure, complete heart block, glaucoma, epilepsy)\n* denial of conditions that alter cortisol release or that require corticosteroid therapy (i.e., Cushing's syndrome, Addison's disease, pituitary tumors, adrenal gland tumors, asthma)\n* denial of severe psychiatric or cognitive conditions that warrant the need for a durable power of attorney (DPOA)\n* able to understand written and verbal English.\n\nExclusion Criteria:\n\n* currently taking oral, injectable, intranasal, topical, or inhaled corticosteroid medications (i.e., prednisone, hydrocortisone, dexamethasone, methylprednisolone, methylprednisolone acetate, triamcinolone, betamethasone, mometasone, fluticasone, budesonide, clobetasol)\n* do not have the technology requirements to complete data collection (i.e., participant does not have a smartphone, tablet, laptop, or desktop computer; lack of reliable internet)\n\nThe following exclusion criteria may affect participants' ability to remain in the study following enrollment:\n\n• Development of complications during surgery that require prolonged hospitalization into Postoperative Day (POD) 2 (e.g., postoperative intubation and ventilation requirements, intractable pain, intractable nausea\u002Fvomiting, signs of infection or sepsis)",true,{"count":170,"type":21},32,[24],"Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients. Older adults (≥65 years) are particularly vulnerable to postoperative complications and their associated morbidities due to the biological aging process. Older adults comprise nearly half of surgical patients worldwide, and this number is expected to increase in the next 10-20 years as the aging population continues to grow. TKA is the most common procedure undergone by older adults, and the rate of TKA procedures is also expected to rise. Despite perioperative guidelines and protocols to prevent postoperative complications, the prevalence of postoperative complications following TKA is approximately 12%. Given these statistics, millions of older adults undergoing TKA may be at risk for postoperative complications and their associated morbidities in the coming decades. Therefore, additional interventions are needed to combat postoperative complications in this population.\n\nThe body's natural response to surgery, also known as the surgical stress response (SSR), contributes to postoperative complications through complex mechanisms involving the autonomic nervous system (ANS). Increased sympathetic nervous system (SNS) activity, or the body's fight-or-flight response, causes dysregulation in feedback systems that regulate the stress response, potentially leading to poorer outcomes. Interventions, such as breathwork, that induce the parasympathetic nervous system (PNS), or the body's rest-and-digest response, have been shown to balance the ANS, regulate stress biology, and improve outcomes. This study will examine the feasibility of adding a breathwork intervention (Box Breathing), compared to an attention control, to standard perioperative care for older adults undergoing TKA. This study will also examine the proof of concept that Box Breathing, compared to an attention control, may help regulate the SSR by assessing an objective measure of stress-related biology, diurnal cortisol rhythm, and gathering self-report information on pain, anxiety, depression, and quality of recovery following TKA.",[174,175,176,177,178,179,180,181,182,183,36,184,185,29],"Surgical Stress Response","Stress Physiological","Stress Physiology","Stress Psychological","Breathing Techniques","Breathing Exercises","Hypothalamic Pituitary Adrenal","Relaxation","Relaxation Therapy","Cortisol","Postoperative Anxiety","Postoperative Depression",[174,187,188,189,179,178,190,36,184,185,35,191],"Total Knee Arthroplasty","Hypothalamic-Pituitary-Adrenal Axis","Breathwork","Postoperative Complications","Diurnal Cortisol Rhythm","2026-03-06",{"date":194,"type":41},"2026-03-11",{"date":133,"type":21},{"date":197,"type":21},"2026-09-30",{"name":199,"class":77},"University of Arizona",{"id":201,"slug":202,"hasResults":11,"nctId":203,"briefTitle":204,"officialTitle":205,"acronym":4,"eligibilityCriteria":206,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":207,"targetDuration":4,"studyType":208,"phases":4,"briefSummary":209,"conditions":210,"keywords":212,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":78},"100607885","validation-of-the-setswana-translated-quality-of-recovery-questionnaire-in-orthopaedic-patients-at-a-tertiary-hospital-in-south-africa-100607885","NCT07194369","Validation of the Setswana Translated Quality of Recovery Questionnaire in Orthopaedic Patients at a Tertiary Hospital in South Africa","Validation of the Setswana Translated Quality of Recovery Questionnaire in Orthopaedic Patients at a Tertiary Hospital in South Africa: a Cross-Sectional Observational Study","Inclusion Criteria:\n\n* Adult patients over 18 years of age\n* Scheduled elective orthopaedic surgery at Dr George Mukhari Academic Hospital\n\nExclusion Criteria:\n\n* Patients who are not fluent in Setswana\n* Patients booked for emergency surgery where a delay to surgery could be detrimental.\n* Patients where the surgery is delayed beyond 10 days of the initial assessment and pre-operative QoR-15 measurement.\n* Patients with a psychiatric disturbance that precludes complete co-operation.\n* Patients with a severe debilitating medical or surgical condition that may limit objective assessment after surgery.\n* Patients with any life threatening postoperative complication.\n* Postoperative confusion or delirium.\n* Patients with a history of recent drug or alcohol abuse which may render responses unreliable.\n* Incomplete QoR-15 questionnaires.",{"count":88,"type":21},"OBSERVATIONAL","This observational study aims to evaluate the validity, reliability and feasibility of the Setswana-translated version of the 15-item Quality of Recovery (QoR-15) questionnaire. The question it aims to answer is:\n\nDoes the Setswana translation of the QoR-15 serve as a valid, reliable and user friendly tool for assessing postoperative recovery in Setswana speaking patients undergoing orthopaedic surgery at a tertiary hospital in Gauteng, South Africa?\n\nThe participants will be asked to complete the Setswana-translated QoR-15 questionnaire both preoperatively and postoperatively.\n\nIn addition, they will be asked to rate their overall postoperative recovery using a visual analog scale (VAS).",[29,211],"Quality of Recovery From Anaesthesia",[213,214],"Setswana translated QoR-15","Quality of Recovery in patients undergoing orthopaedic surgery","2025-09-18",{"date":217,"type":41},"2025-09-26",{"date":219,"type":21},"2025-10-15",{"date":221,"type":21},"2025-12-30",{"name":223,"class":77},"Sefako Makgatho Health Sciences University",{"id":225,"slug":226,"hasResults":11,"nctId":227,"briefTitle":228,"officialTitle":229,"acronym":230,"eligibilityCriteria":231,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":232,"enrollmentInfo":233,"targetDuration":4,"studyType":22,"phases":235,"briefSummary":236,"conditions":237,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":240,"lastUpdatePostDateStruct":241,"startDateStruct":243,"completionDateStruct":245,"leadSponsor":247,"locationsCount":4},"100589640","intertransverse-process-block-for-quality-of-recovery-post-open-hepatectomy-100589640","NCT06957041","Intertransverse Process Block for Quality of Recovery Post-Open Hepatectomy","Effect of Intertransverse Process Block on the Quality of Recovery Post-Open Hepatectomy: A Pilot Non-Randomised Study of Intervention","ITPB QoR","Inclusion Criteria:\n\n\\- Adult patients aged 18-75 years of ASA I - III physical status classification undergoing open hepatectomy for benign or malignant liver lesion.\n\nExclusion Criteria:\n\n* Patient refusal\n* Patients who are unable to comprehend the QoR15 form\n* Local or systemic infection\n* Coagulopathy leading to absolute contraindication to regional anesthesia\n* Contraindication to local anaesthetics (LA) such as LA allergy","75 Years",{"count":234,"type":21},20,[24],"The study aims to assess the analgesic efficacy of the ITPB at the retro-SCTL space in patients undergoing major open hepatectomy surgery. This is assessed by:\n\nPrimary Objective:\n\nPrimary outcome measure:\n\n● Assessing the quality of recovery 15 (QoR15) score at 24 and 48 hours\n\nSecondary outcome measure:\n\n* Number of anaesthetic and hypoesthetic dermatomes on the ventral and dorsal aspect of the thorax on both the sides at 30 minutes of block completion and during the post anaesthetic room (PACU) discharge\n* Assessing the 24-hour area under the curve of postoperative pain numerical rating score (NRS, 0-10) at rest and deep breathing or upon use of triflow.\n* Assessing the amount of postoperative morphine (mg) equivalent consumption at 24 and 48 hours\n* Time to discharge from High dependency unit (HDU) or Intensive care unit (ICU)\n\nHypothesis:\n\nThe investigators hypothesize that the application of ITPB targeting the retro-SCTL space in patients undergoing open hepatectomy will improve overall quality of recovery and pain score.",[238,239,29],"Hepatectomy","Intertransverse Process Block","2025-04-25",{"date":242,"type":41},"2025-05-04",{"date":244,"type":21},"2025-05-01",{"date":246,"type":21},"2026-10-01",{"name":248,"class":77},"Chinese University of Hong Kong"]