[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"race-related-stress\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:race-related-stress":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":27,"conditions":28,"keywords":33,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":5},"100491917","phase-1-acceptance-and-commitment-therapy-for-adolescents-and-young-adults-with-sickle-cell-disease-100491917",false,"NCT05685368","Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease","Using Acceptance and Commitment Therapy (ACT) to Promote Mental Health and Transition Readiness in Youth With Sickle Cell Disease: A Community-Based Participatory Action Research (CBPAR) Approach","ACT for SCD","Youth Participant Inclusion and Exclusion Criteria The inclusion criteria for study participation are Be an adolescent and\u002For young adult (age 14-21) who has Sickle Cell Disease Willing to enroll in the ACT group jointly provided by the Division of Adolescent and Young Adult Medicine\u002FDepartment of Hematology and Oncology Participants can be active, waitlisted, or new patients at CHLA Participants must be able to understand and speak English, as the therapy will only be delivered in English Participants must have an English-speaking parent\u002Fguardian Able to provide consent\u002Fassent An adolescent or young adult that is pregnant is eligible to participate if consent can be obtained Participants must be developmentally typical Have a stable internet connection (via computer, tablet, or phone) with access to a webcam and a private space to engage in a group therapy sessions; Must consent to audio and video recording of initial interview. Must agree to attend 6 weekly ACT group session Youth participants will be asked to become a member of the CAB. To become a CAB member, the youth participant must consent\u002Fassent to participation in the ACT intervention. If a CAB member, they must be willing to engage in CAB interviews and meetings.\n\nThe exclusion criteria are:\n\nPrisoners or youth in detention centers Unable to understand or speak English Does not have SCD Clients who are at significant risk for suicide and self-injury will be excluded due to the intense levels of support required to support these individuals which would interfere with study procedures.\n\nAdolescents with families that require frequent intervention from the Department of Children and Family Services, are currently experiencing psychosis, or have severe health concerns that will impact study participation or attendance will be excluded.","ALL","14 Years","21 Years",{"count":21,"type":22},66,"ESTIMATED","INTERVENTIONAL",[25,26],"PHASE1","PHASE2","The current study seeks to build on previous research that demonstrates the efficacy of Acceptance and Commitment Therapy in combating stigma by investigating the feasibility and acceptability of a protocol to support Black adolescents and young adults in coping with race related stress. The study will consist of a small, purposeful, non-randomized sample (N = 30) of clients enrolled into a 10-session Acceptance and Commitment Therapy group. The group will be offered as part of regular clinical care at the Division of Adolescent and Young Adult Medicine. Three consecutive groups will be run with approximately 8-10 participants in each group over the next year.",[29,30,31,32],"Race-related Stress","Depression, Anxiety","Quality of Life","Stress Reaction",[34,35,36,37,38,39,40],"Black","African American","Adolescents","Acceptance and Commitment Therapy","race-related stress","racial trauma","coping","RECRUITING","2026-04-30",{"date":44,"type":45},"2026-05-06","ACTUAL",{"date":47,"type":45},"2025-04-01",{"date":49,"type":22},"2029-06-30",{"name":51,"class":52},"Children's Hospital Los Angeles","OTHER"]