[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"radiation-dose-reduction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:radiation-dose-reduction":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100608249","multicenter-pediatric-low-dose-ct-protocol-development-and-clinical-verification-100608249",false,"NCT07199101","Multicenter Pediatric Low-Dose CT Protocol: Development and Clinical Verification","Development of a Multicenter Low-Dose CT Protocol for Children Based on Low-Dose Simulation Technology and Verification by Clinical Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 0-17 years.\n* Pediatric patients for whom a CT examination is deemed necessary by an attending physician.\n\nExclusion Criteria:\n\n* Parents\u002Fguardians refuse to consent to low-dose CT examination.\n* Pediatric patients are in critical condition, with no time allocated for explanation of the randomized controlled trial (RCT) protocol.","ALL","0 Years","18 Years",{"count":20,"type":21},2650,"ESTIMATED","INTERVENTIONAL",[24],"NA","Children are sensitive to ionizing radiation, and there are significant regional variations in current pediatric CT radiation doses. Although there are studies on low-dose CT targeting single lesions, these studies require clear clinical indications and support from advanced equipment, making widespread promotion difficult. The establishment of low-dose CT protocols is mostly experience-based; when radiologists lack confidence in image quality, the credibility of diagnostic reports is compromised. Therefore, the development of low-dose protocols must meet the diagnostic confidence of most radiologists, enable clear visualization of key anatomical structures in clinical practice, and satisfy the requirements for disease diagnosis.\n\nThe purpose of this study is to establish a pediatric low-dose CT scanning protocol using Low-dose Simulation of CT (LDS) technology, and conduct a multicenter randomized controlled trial (RCT) in clinical settings to verify the clinical feasibility of this low-dose CT scanning protocol.",[27],"Radiation Dose Reduction",[29,30,31],"Tomography, X-ray computed","Child","radiation dose","NOT_YET_RECRUITING","2025-09-22",{"date":35,"type":36},"2025-09-30","ACTUAL",{"date":38,"type":21},"2026-01-01",{"date":40,"type":21},"2027-12-31",{"name":42,"class":43},"Beijing Children's Hospital","OTHER",20]