[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"radical-cystectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:radical-cystectomy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,67,90],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100530700","early-phase-1-prophylactic-antibiotics-in-cystectomy-with-diversion-100530700",false,"NCT06190197","Prophylactic Antibiotics in Cystectomy With Diversion","Prophylactic Antibiotics in Radical Cystectomy With Urinary Diversion","Inclusion Criteria:\n\n* Presence of muscle invasive bladder cancer and planning to undergo radical cystectomy with either ileal conduit or neobladder diversion.\n* 18 years of age or older\n\nExclusion Criteria:\n\n* Currently receiving antimicrobials for active infection\n* Poor renal function with GFR \\\u003C 30 ml\u002Fmin\n* Allergy to nitrofurantoin and unable to take an alternative antibiotic (cephalexin, trimethoprim-sulfamethoxazole, or ciprofloxacin)\n* Pregnancy\n* Unable to provide Informed consent\n* Prior pelvic radiation","ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"EARLY_PHASE1","Using a randomized 2 arm design, this study is being conducted to test for non-inferiority of no prophylactic antibiotic therapy versus the prophylactic oral antibiotic, nitrofurantoin, through comparison of rates of postoperative urinary tract infections within the 90-day postoperative period in patients with muscle invasive bladder cancer who undergo radical cystectomy with urinary diversion.",[26,27,28,29],"Muscle-Invasive Bladder Carcinoma","Radical Cystectomy","Ileal Conduit","Neobladder Diversion","RECRUITING","2025-11-13",{"date":33,"type":34},"2025-11-17","ACTUAL",{"date":36,"type":34},"2024-05-13",{"date":38,"type":20},"2027-10-15",{"name":40,"class":41},"University of Minnesota","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":52,"studyType":53,"phases":4,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":4},"100347644","post-surgical-delirium-in-patients-undergoing-radical-cystectomy-100347644","NCT03806439","Post-surgical Delirium in Patients Undergoing Radical Cystectomy.","Inclusion Criteria:Adult patients undergoing radical cystectomy. -\n\nExclusion Criteria: Patient refusal.\n\n\\-","99 Years",{"count":51,"type":20},100,"12 Months","OBSERVATIONAL","Post-surgical delirium in patients undergoing radical cystectomy. Introduction Delirium occurs after major abdominal surgery may reach about 15% of the patients.(1)\n\nAim The aim of this study is to determine the incidence of delirium after radical cystectomy surgery and the associated risk factors in Alexandria University hospital.\n\nPatients and Methods After approval of local ethical committee and patient consent, the study will be done on patients undergoing radical cystectomy surgery in Alexandria University hospitals from January 5th 2019 till January 4th 2020. The 6-item Cognitive Impairment Test (6CIT) and SPMSQ questionnaire will be used. SPMSQ will be done preoperative and daily for 3 days postoperative, at day 7. Phone call for SPMSQ will be done 3, 6, 9 and 12 months after surgery.",[56,27],"Delirium","NOT_YET_RECRUITING","2025-03-31",{"date":60,"type":34},"2025-04-03",{"date":62,"type":20},"2028-11-25",{"date":64,"type":20},"2029-11-24",{"name":66,"class":41},"University of Alexandria",{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":79,"conditions":80,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":42},"100576327","outcomes-of-uretheroileal-suspension-technique-during-open-radical-cystectomy-100576327","NCT06783855","Outcomes of Uretheroileal Suspension Technique During Open Radical Cystectomy","Outcomes of Uretheroileal Suspension Technique During Open Radical Cystectomy and Ileal Neobladder: A Prospective Randomized Comparative Study","Inclusion Criteria:\n\n* Patient age \\>18 years.\n* Muscle-invasive bladder carcinoma (MIBC).\n* Non-muscle-invasive bladder carcinoma (NMIBC) fulfilling the following criteria:\n\n  1. \\- (recurrent disease that is unresponsive to other treatments\n  2. \\- high-grade tumors (T1, carcinoma in situ) refractory to intravesical therapy\n  3. -Multifocal or recurrent high-grade tumors despite intravesical therapy and the tumor progression from NMIBC to MIBC).\n\nExclusion Criteria:\n\n* NMIBC or benign disease.\n* Severe hepatic renal dysfunction.\n* Urethral involvement with bladder carcinoma.\n* Poor overall health status.\n* Severe renal dysfunction.","80 Years",{"count":76,"type":20},60,[78],"NA","The suspension technique is reported as the puboprostatic ligaments that attach the prostate to the symphysis pubis. After the ligating the complex, including both the dorsal vein complex and the puboprostatic ligaments, this complex was sharply divided anteriorly from the prostate with a safe distance (1-2 mm), and the urethra is defined and divided. After removing the prostate, the ileal pouch is reconstructed by completely everting the mucosa and sutured outward with a running 4-0 absorbable suture around the edge. The neck of the neobladder was narrowed to ≈1 cm, for convenient passage of a 20 F catheter. Anastomotic sutures of 3-0 absorbable polyglactin were placed at the 1, 3, 5, 6, 7, 9, 11 and 12 o'clock positions",[27],"2025-01-17",{"date":83,"type":34},"2025-01-22",{"date":85,"type":34},"2025-01-01",{"date":87,"type":20},"2027-01-01",{"name":89,"class":41},"Sohag University",{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":4,"eligibilityCriteria":96,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":97,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":99,"conditions":100,"keywords":116,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":42},"100529161","study-on-the-quality-of-life-and-pathological-state-in-patients-who-underwent-radical-cystectomy-100529161","NCT06170177","Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy","Bladder Archive: Observational Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy","Inclusion Criteria:\n\n* subjects underwent radical cystectomy\n* \\> 18 years old\n* Ability to read and sign the informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* Inability to read and sign the informed consent",{"count":98,"type":20},4000,"Observational study on the quality of life and pathological state of patients underwent radical cystectomy.",[26,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,27],"Muscle Invasive Bladder Urothelial Carcinoma","Bladder Cancer TNM Staging","Bladder Cancer Stage IIa","Bladder Cancer Stage IIb","Bladder Cancer Stage IV","Bladder Leiomyosarcoma","Bladder Cancer","Bladder Cancer Stage II","Bladder Cancer Stage IIIa","Bladder Cancer Stage IIIb","Bladder Cancer Stage IIIc","Bladder Urothelial Carcinoma","Progression, Disease","Urinary Diversion","Neobladder",[27],"2023-12-06",{"date":119,"type":34},"2023-12-14",{"date":121,"type":34},"2013-02-04",{"date":123,"type":20},"2063-02",{"name":125,"class":41},"IRCCS San Raffaele"]