[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"radicular-low-back-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:radicular-low-back-pain":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100617049","r-rehab-pathway-versus-usual-care-after-lumbar-radicular-surgery-100617049",false,"NCT07313566","R³ Rehab Pathway Versus Usual Care After Lumbar Radicular Surgery","An Evidence-based Rehabilitation Pathway for Patients Undergoing Surgery for Lumbar Radicular Pain to Promote Return to Work: a Cluster Randomized Trial Comparison With Usual Care.","R³","Inclusion Criteria:\n\n* Radicular pain (for ≥ 6 weeks prior to screening), with a clear indication for lumbar spinal surgery ((micro)discectomy, decompression and\u002For fusion), in accordance with the KCE guidelines (when evidence-based multimodal management has not improved pain or function and radiological findings are consistent with clinical symptoms)\n* Employed (working or on sick leave for less than 1 year due to spinal pathology)\n* Age 18 - 65 years\n* Surgery is scheduled within a timeframe of five days to 2 months after the decision for surgery (4 months for fusion)\n* For lumbar fusion surgery, the fusion should be restricted to one or two levels\n* Able to provide written informed consent, implying that the participant is both physically and cognitively capable of understanding the study information and signing the consent form independently.\n\nExclusion Criteria:\n\nPatients are not eligible for the trial in case of any of the following criteria:\n\n* Lumbar surgery performed for malignant disease, spinal fracture, infectious spinal disease\n* Insufficient knowledge of Dutch or French language to receive education in the recruiting center and to complete the questionnaires (consistent with the language spoken in the recruiting centre)\n* Immediate surgery via emergency admission that precludes prehabilitation\n* Revision fusion surgery\n* Non-residency in Belgium","ALL","18 Years","65 Years",{"count":21,"type":22},480,"ESTIMATED","INTERVENTIONAL",[25],"NA","The R³ trial is a multicentre cluster randomized controlled trial evaluating an evidence-based, person-centred rehabilitation pathway for patients undergoing lumbar surgery for radicular pain. The pathway includes structured pre-, peri-, and postoperative rehabilitation, early postoperative mobilization, case management, early return-to-work (RTW) guidance, and patient empowerment. Clusters (hospitals) are randomized to implement the R³ pathway (intervention) or continue usual care (control). The primary aim is to determine whether the R³ pathway reduces time to return to work compared with usual care.",[28,29],"Lumbar Radiculopathy","Radicular Low Back Pain",[31,32,33,34,35,36],"Lumbar radiculopathy","Return to work","Case manager","Cluster RCT","Rehabilitation","radicular pain","RECRUITING","2026-04-28",{"date":40,"type":41},"2026-05-05","ACTUAL",{"date":43,"type":41},"2026-03-16",{"date":45,"type":22},"2028-05",{"name":47,"class":48},"Universitaire Ziekenhuizen KU Leuven","OTHER",16,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":80},"100621174","the-role-of-temporal-changes-in-pain-response-after-transforaminal-epidural-steroid-injection-on-treatment-success-100621174","NCT07367191","The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Pre-procedural Numeric Rating Scale (NRS) pain score of 4 or higher\n* Presence of segmental lumbar disc herniation demonstrated on magnetic resonance imaging (MRI) consistent with clinical findings\n* Undergoing fluoroscopy-guided transforaminal epidural steroid injection due to insufficient response to conservative treatments, as determined by the algology clinic\n\nExclusion Criteria:\n\n* Presence of spondylolisthesis, scoliosis, or lumbar spinal stenosis accompanying lumbar disc herniation\n* Presence of malignancy\n* History of lumbar spine surgery for disc herniation\n* Transforaminal epidural steroid injection within the previous 6 months\n* Requirement for repeat epidural steroid injection during the data collection or follow-up period\n* Inability to be contacted for follow-up assessments by telephone",{"count":57,"type":22},120,"OBSERVATIONAL","Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation. Although TFESI has been shown to provide significant pain relief in a substantial proportion of patients, the onset, duration, and temporal pattern of pain relief after the procedure vary considerably among individuals. The relationship between early pain response patterns and long-term treatment success remains poorly understood.\n\nThis prospective observational study aims to evaluate whether temporal changes in pain intensity following TFESI, particularly during the early post-procedural period, are associated with clinical treatment success at mid- and long-term follow-up. Pain intensity will be assessed using the Numeric Rating Scale (NRS) at predefined time points following the procedure, and treatment success will be defined as a ≥50% reduction in NRS score compared with baseline.",[61,28,29,62],"Lumbar Disc Herniation","Sciatica",[64,65,66,67,68,69],"TFESI","Temporal Pain Response","Numeric Rating Scale","NRS","Transforaminal Epidural Steroid Injection","Treatment Success","NOT_YET_RECRUITING","2026-01-16",{"date":73,"type":41},"2026-01-26",{"date":75,"type":22},"2026-02-15",{"date":77,"type":22},"2026-10-15",{"name":79,"class":48},"Marmara University",1]