[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"radicular-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:radicular-pain":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,51,85,114,155],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100635833","transcutaneous-auricular-vagus-nerve-stimulation-combined-with-cervical-epidural-injection-for-cervical-radiculopathy-100635833",false,"NCT07557823","Transcutaneous Auricular Vagus Nerve Stimulation Combined With Cervical Epidural Injection for Cervical Radiculopathy","Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Combined With Cervical Epidural Injection in the Treatment of Cervical Radiculopathy: A Randomized, Double-Blind, Sham-Controlled Trial.","Inclusion Criteria:\n\n1. Age between 18 and 85 years old.\n2. Body Mass Index (BMI) between 18 and 35 kg\u002Fm².\n3. American Society of Anesthesiologists (ASA) physical status I to III.\n4. Diagnosed with cervical radiculopathy, scheduled for selective cervical epidural injection.\n5. Estimated procedure duration ≤ 1 hour.\n6. Able to understand and provide written informed consent.\n\nExclusion Criteria:\n\n1. Arrhythmia requiring treatment, severe bradycardia, or postural orthostatic tachycardia syndrome.\n2. Neuromuscular disorders or auricular dermatitis.\n3. Cervical fracture, tumor, tuberculosis, or active infection confirmed by imaging.\n4. Contraindications to vagus nerve stimulation: carotid sinus hypersensitivity, bilateral carotid artery stenosis.\n5. Severe psychiatric disorder or history of substance abuse.","ALL","18 Years","85 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","This is a prospective, randomized, double-blinded, sham-controlled trial conducted to investigate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) combined with cervical epidural injection in the treatment of cervical radiculopathy. A total of 80 subjects will be enrolled and randomly assigned (1:1) to either the experimental group or the control group. The primary outcome measure is the proportion of subjects with a ≥50% reduction in the Numerical Rating Scale (NRS) pain score at discharge. Secondary outcomes include pain intensity, pain interference, psychological status, sleep quality, physical disability, and autonomic function measurements. Adverse events will be monitored throughout the study.",[27,28,29],"Cervical Radiculopathy","Cervical Spondylosis","Radicular Pain",[31,32,33,34,35,36,37],"taVNS","transcutaneous auricular vagus nerve stimulation","cervical epidural injection; cervical radiculopathy","pain","arm pain","pain management","neuromodulation","NOT_YET_RECRUITING","2026-04-26",{"date":41,"type":42},"2026-04-29","ACTUAL",{"date":44,"type":21},"2026-04-10",{"date":46,"type":21},"2027-03-31",{"name":48,"class":49},"Second Affiliated Hospital, School of Medicine, Zhejiang University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":4,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":50},"100614529","cgm-based-glycemic-analysis-after-esi-100614529","NCT07280780","CGM-Based Glycemic Analysis After ESI","Continuous Glucose Monitoring-Based Evaluation of Glycemic Fluctuations Following Epidural Steroid Injections: A Comparative Study by Diabetic Status","CGMSteroid","Inclusion Criteria:\n\n* Adults aged 20 to 60 years.\n* Patients scheduled for cervical or lumbar epidural steroid injection at the pain clinic.\n* Patients capable of understanding and using a Continuous Glucose Monitoring (CGM) device.\n\nExclusion Criteria:\n\n* Patients currently taking or administering steroid medications.\n* Patients with Type 1 Diabetes Mellitus.\n* Patients with Cushing's disease.\n* Patients who have received an epidural steroid injection within the last 3 months.\n* Patients with a known allergy to contrast media.\n* Patients taking anticoagulants or antiplatelet agents.\n* Patients unable to use a Continuous Glucose Monitoring (CGM) device.","20 Years","60 Years",{"count":62,"type":21},36,"OBSERVATIONAL","The goal of this clinical study is to learn how blood glucose levels change after an epidural steroid injection (ESI) with dexamethasone in adults. It will specifically compare the glycemic response between patients with type 2 diabetes and those without diabetes.\n\nThe main questions it aims to answer are:\n\nDoes the injection cause higher or longer-lasting blood glucose elevation in diabetic patients compared to non-diabetic patients? How do the mean glucose level and Time in Range (TIR) change after the injection in both groups?\n\nResearchers will compare a Type 2 Diabetes group to a Non-Diabetes group to see the differences in glycemic fluctuations using a continuous glucose monitoring (CGM) device.\n\nParticipants will:\n\n* Wear a small CGM sensor on their arm for about 15 days to monitor blood glucose levels continuously\n* Receive an epidural steroid injection containing 5 mg of dexamethasone on Day 3\n* Visit the clinic 3 times (Day 1, Day 3, and Day 15) for sensor attachment, the injection procedure, and data collection",[66,67,29,68,69],"Type 2 Diabetes (T2DM)","Hyperglycemia","Spinal Stenosis","Intervertebral Disc Herniation",[71,72,73,74,75],"epidural steroid injection","Continuous Glucose Monitoring","Dexamethasone","Glycemic Variability","Time in range","2026-04-07",{"date":78,"type":42},"2026-04-09",{"date":80,"type":21},"2026-04-20",{"date":82,"type":21},"2026-12-31",{"name":84,"class":49},"Korea University Anam Hospital",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":63,"phases":4,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":50},"100631040","patient-satisfaction-during-lomber-transforaminal-epidural-steroid-injection-the-role-of-sedation-anxiety-and-pain-100631040","NCT07495501","Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain","Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain: A Prospective Observational Study","Inclusion Criteria:\n\n* Adults aged 18 to 80 years\n* No prior history of any interventional pain procedure\n* Ability to read and write in Turkish and to complete the study questionnaires\n* Written informed consent provided.\n* Planned lumbar transforaminal epidural steroid injection for radicular pain\n\nExclusion Criteria:\n\n* Refusal to provide written informed consent.\n* Inability to complete the satisfaction questionnaires reliably due to lack of Turkish literacy, significant cognitive impairment or severe visual or hearing impairment\n* Presence of major comorbidities such as decompensated cardiac or respiratory failure, uncontrolled arrhythmia or angina, myocardial infarction or stroke within the past 3 months, advanced liver or kidney failure, uncontrolled obstructive sleep apnea associated with morbid obesity, or severe pulmonary hypertension.","80 Years",{"count":94,"type":21},120,"Transforaminal epidural steroid injection (TFESI) is a minimally invasive procedure commonly used for the management of lumbar radicular pain. It is intended to reduce inflammation around the affected nerve root, limit edema, and modulate nociceptive transmission, with the aim of relieving pain, improving physical function, and potentially reducing the need for surgery. Although TFESI may improve function and quality of life, treatment benefit is not uniform, and the degree of pain relief and patient satisfaction may differ across individuals.\n\nThis prospective observational study aims to evaluate postprocedural pain intensity and patient satisfaction in individuals undergoing lumbar TFESI and to identify clinical and demographic factors associated with satisfaction. Demographic and clinical characteristics, medical and surgical history, procedural pain scores, anxiety level, postprocedural pain scores, sedation status, fluoroscopy-related metrics, and intraprocedural events will be recorded. Patient satisfaction will be assessed 1 hour after the procedure using a Likert-based questionnaire, and operator satisfaction will also be documented.\n\nBy examining patient-reported outcomes together with procedural and clinical variables, this study seeks to provide a more standardized assessment of real-world TFESI outcomes and to support better patient selection and follow-up strategies.",[97,98,29],"Lumbar Disc Disease","Radiculopathy Lumbar",[100,101,102,103,104],"Patient satisfaction","Sedation","Anxiety","Epidural steroid injection","Pain intensity","2026-03-21",{"date":107,"type":42},"2026-03-27",{"date":109,"type":21},"2026-04-01",{"date":111,"type":21},"2026-09-15",{"name":113,"class":49},"Mersin University",{"id":115,"slug":116,"hasResults":11,"nctId":117,"briefTitle":118,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":22,"phases":124,"briefSummary":125,"conditions":126,"keywords":129,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":4},"100612081","contralateral-neural-tissue-mobilization-for-cervical-radiculopathy-100612081","NCT07248943","Contralateral Neural Tissue Mobilization for Cervical Radiculopathy","Contralateral Neural Tissue Mobilization for Cervical Radiculopathy: An Exploratory Study","NTM","Inclusion Criteria:\n\n* Age 18 years or older Presence of unilateral upper-extremity pain in a dermatomal distribution consistent with cervical radiculopathy (with or without neck pain)\n* Able to read and understand English\n* Willing and able to provide written informed consent\n* New patient to the clinic or established patient who meets inclusion criteria and has not previously received neural tissue mobilization as part of treatment\n\nExclusion Criteria:\n\n* Bilateral upper-extremity pain\n* Upper-extremity pain that is non-dermatomal in distribution\n* Presence of contraindications or precautions preventing use of the contralateral limb for neural tissue mobilization (e.g., injury, allodynia, recent surgery, postsurgical complications)\n* Not willing to participate in the study",{"count":123,"type":21},40,[24],"Cervical radiculopathy (CR) is a common form of peripheral neuropathic pain characterized by neck and upper extremity symptoms in a dermatomal distribution. Neural tissue mobilization (NTM) is an intervention shown to provide benefit for neuropathic pain presentations; however, some patients are unable to tolerate direct treatment of the symptomatic limb due to allodynia, hyperalgesia, or fear of movement. Early evidence from lower-extremity research suggests that contralateral NTM may produce therapeutic effects similar to ipsilateral treatment, but this approach has not been investigated in individuals with upper-extremity symptoms.\n\nThis exploratory case series aims to examine the immediate effects of contralateral NTM in adults presenting to outpatient physical therapy with CR. Participants will undergo pre- and post-treatment assessments of pain intensity, disability, fear-avoidance beliefs, pain distribution, and neurodynamic mechanosensitivity. Findings will provide preliminary evidence regarding whether contralateral NTM may serve as a viable treatment option when direct symptomatic limb treatment is not tolerated.",[27,127,128,29],"Pain","Neuropathic Pain",[27,128,130,131,29,132,133,134,135,136,137,138,139,140,141,142,143,144,145],"Peripheral Neuropathic Pain","Upper Extremity Pain","Cervical Spine Disorders","Nerve Root Compression","Neural Tissue Mobilization","Neurodynamic Mobilization","Neurodynamics","Contralateral Treatment","Median Nerve Mobilization","Upper Limb Neurodynamic Test (ULNT1a)","Physical Therapy","Musculoskeletal Pain","Pain Phenotyping","Manual Therapy","Rehabilitation","Mechanosensitivity","2025-11-18",{"date":148,"type":42},"2025-11-25",{"date":150,"type":21},"2025-12",{"date":152,"type":21},"2026-09",{"name":154,"class":49},"Evidence In Motion",{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":161,"eligibilityCriteria":162,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":163,"targetDuration":4,"studyType":63,"phases":4,"briefSummary":165,"conditions":166,"keywords":169,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":177,"lastUpdatePostDateStruct":178,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":184,"locationsCount":50},"100573544","reliability-of-mri-and-ultrasound-in-cervical-epidural-needle-depth-estimation-100573544","NCT06747663","Reliability of MRI and Ultrasound in Cervical Epidural Needle Depth Estimation","Reliability of MRI and Ultrasound in Predicting Needle Depth During Cervical Epidural Injections: a Methodological Observational Study","CERV-MRI-USG","Inclusion Criteria:\n\nAge ≥ 18 years, Diagnosed with chronic cervical pain, Referred for cervical epidural steroid injection, Patients capable of providing informed consent.\n\nExclusion Criteria:\n\nAge \\\u003C 18 years, Pregnancy or breastfeeding, History of coagulation disorders or use of anticoagulants, Severe systemic infections or local infections at the injection site, Known allergy to steroids or local anesthetics, Uncontrolled diabetes mellitus, Patients with spinal tumors or significant spinal deformities, Previous cervical spine surgery, Cognitive impairment preventing informed consent or follow-up participation.",{"count":164,"type":21},90,"This study aims to evaluate the reliability of magnetic resonance imaging (MRI) and ultrasound (USG) in predicting needle depth during cervical epidural injections, compared to fluoroscopy. The goal is to identify alternative imaging methods that reduce radiation exposure while maintaining procedural accuracy and patient safety.",[167,29,168],"Chronic Neck Pain","Cervical Epidural Injection",[170,171,172,173,174,175,176],"Cervical Epidural Steroid Injection","Needle Depth Estimation","Ultrasound Guidance","MRI Guidance","Fluoroscopy","Radiation Exposure","Chronic Pain Management","2024-12-18",{"date":179,"type":42},"2024-12-24",{"date":181,"type":21},"2025-01",{"date":183,"type":21},"2025-07",{"name":185,"class":49},"Damla Yürük"]