[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"radiculopathy-multiple-sites\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:radiculopathy-multiple-sites":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100633807","the-selective-intraperineural-nerve-root-block-study-100633807",false,"NCT07531485","The Selective Intraperineural Nerve Root Block Study","Feasibility, Safety and Diagnostic Accuracy of Selective Intraperineural Nerve Root Block for Identifying Compressed Nerve Root in Lumbosacral Radicular Pain. A Prospective Cohort Study","SINRBS","Inclusion Criteria\n\n* Unilateral sciatica \\>1 month with activity\u002Fdaily life impairment.\n* Suspected L5\u002FS1 root compression at L4-5\u002FL5-S1 with unconfirmed pain correlation, including disc herniation (MSU 1-B\u002F1-A\u002F2-A), lateral recess\u002Fforaminal stenosis (Lee grade 2\u002F3), atypical sciatica, or imaging-exam inconsistency.\n* Candidates for single-segment, single-root lumbar decompression, electing surgery after informed consent.\n\nExclusion Criteria\n\n* No significant pre-SINRB\u002Fsurgery pain, or weakness\u002Fnumbness as primary symptom.\n* Unidentifiable responsible compressed nerve root (RCNR) per surgery.\n* Suspected compression of the same nerve root at more than one segment.\n* Pregnancy, active malignancy, or surgical contraindications.\n* Inability to cooperate with assessment due to comorbidities or dysfunction.","ALL","18 Years","90 Years",{"count":21,"type":22},80,"ESTIMATED","INTERVENTIONAL",[25],"NA","Before lumbosacral decompression surgery for radicular pain, selective nerve root block(SNRB) is a common procedure to identify the responsible compressed nerve root(RCNR) and predict surgical outcomes. However, the diagnostic accuracy of conventional SNRB is unsatisfactory, especially in terms of specificity. The main limitation is the uncontrolled distribution of anesthetics during injection: when anesthetics spread to surrounding soft tissues instead of acting directly on the RCNR, false-negative results may occur with persistent radicular pain; when anesthetics diffuse to two or more nerve roots including the RCNR, false-positive results may occur even if a normal nerve root is punctured, leading to misdiagnosis.\n\nThis study aims to evaluate the diagnostic accuracy of a novel three-dimensional computed tomography multiplanar volume reconstruction (3D-CT MPVR) guided selective intraperineural nerve root block(SINRB) for identifying the RCNR in patients with lumbosacral radicular pain. The investigators hypothesize that this technique will achieve higher diagnostic specificity and overall accuracy than conventional SNRB, by ensuring anesthetics are delivered directly to the target nerve root. This improvement will help clinicians make more accurate surgical plans, achieve better targeted decompression, and ultimately improve postoperative pain relief and functional recovery for patients.\n\nThe main research questions to be addressed in this study are:\n\n* What is the procedural success rate of SINRB?\n* Whether SINRB may cause clinically detectable nerve injury?\n* Whether sciatica is relieved after SINRB when only the responsible compressed nerve root is blocked?\n* Whether sciatica is relieved after SINRB when only a normal unaffected nerve root is blocked?\n\nParticipants will:\n\n* Undergo one or two SINRB procedures and a single-level lumbar decompression surgery\n* Get assessment of pain, mobility disorder and neurological function",[28,29,30,31,32],"Radiculopathy Lumbar","Radiculopathy Sacral","Radiculopathy Multiple Sites","Herniated Disc","Foraminal Stenosis",[34,35,36,37],"intraperineural","3D-CT MPVR","diagnostic selective nerve root block","lumbosacral radiculopathy","NOT_YET_RECRUITING","2026-04-11",{"date":41,"type":42},"2026-04-15","ACTUAL",{"date":44,"type":22},"2026-04-13",{"date":46,"type":22},"2027-01-01",{"name":48,"class":49},"Xi'an Honghui Hospital","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":80},"100548481","impact-of-direct-current-electrical-stimulation-on-treatment-of-lumbosacral-radiculopathy-100548481","NCT06421558","Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy","Impact of Direct Current Neuromuscular Electrical Stimulation on Physical Therapy Treatment of Lumbosacral Radiculopathy","Inclusion Criteria:\n\n* Must show evidence of lumbo-sacral radiculopathy as determined by EMG and straight leg raise test.\n* Must be able to attend weekly sessions for the 6-week period of the study (no extended travel)\n* Must be at least 18 years old.\n\nExclusion Criteria:\n\n* Currently pregnant\n* Cardiac pacemaker\n* Active or recent cancer\n* Active or recent blood clots\n* History of epilepsy\n* Open wounds\n* Spinal fusion surgery",{"count":59,"type":22},150,[25],"This study will compare two methods of electrical stimulation (alternating current and direct current) as an adjunctive therapy to treating lumbosacral radiculopathy. Both types of electrical stimulation have been used in clinical practice for physical therapy, however direct current stimulation is much less common and there is less known about its impact on physical therapy outcomes. The aim of this project is to show the efficacy of a novel device, the Neubie direct current device, compared to traditional TENS unit in clinical physical therapy treatment of radiculopathy. Outcomes measured will include: pain intensity, functional status, neurological status, electrophysiological changes and patient satisfaction.",[28,29,30],[64,65,66,67,68],"electrical stimulation","direct current","e-stim","neubie","emg","RECRUITING","2024-07-25",{"date":72,"type":42},"2024-07-29",{"date":74,"type":42},"2024-04-01",{"date":76,"type":22},"2025-08-01",{"name":78,"class":79},"NeuFit - Neurological Fitness and Education","INDUSTRY",16]